DE3482588D1 - Androstan-17beta-carbonsaeureester, ein prozess und zwischenprodukte fuer ihre herstellung, kompositionen und methode zur behandlung inflammatorischer zustaende. - Google Patents

Androstan-17beta-carbonsaeureester, ein prozess und zwischenprodukte fuer ihre herstellung, kompositionen und methode zur behandlung inflammatorischer zustaende.

Info

Publication number
DE3482588D1
DE3482588D1 DE8484850348T DE3482588T DE3482588D1 DE 3482588 D1 DE3482588 D1 DE 3482588D1 DE 8484850348 T DE8484850348 T DE 8484850348T DE 3482588 T DE3482588 T DE 3482588T DE 3482588 D1 DE3482588 D1 DE 3482588D1
Authority
DE
Germany
Prior art keywords
sub
hydrogen
compounds
inflammational
17beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8484850348T
Other languages
English (en)
Inventor
Ralph Lennart Brattsand
Bror Arne Thalen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Draco AB
Original Assignee
Draco AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Draco AB filed Critical Draco AB
Application granted granted Critical
Publication of DE3482588D1 publication Critical patent/DE3482588D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE8484850348T 1983-11-18 1984-11-09 Androstan-17beta-carbonsaeureester, ein prozess und zwischenprodukte fuer ihre herstellung, kompositionen und methode zur behandlung inflammatorischer zustaende. Expired - Lifetime DE3482588D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8306370A SE8306370D0 (sv) 1983-11-18 1983-11-18 Novel androstane-17beta-carboxylic acid esters, a process and intermediates for their preparation, compositions and method for the treatment of inflammatory conditions

Publications (1)

Publication Number Publication Date
DE3482588D1 true DE3482588D1 (de) 1990-08-02

Family

ID=20353384

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8484850348T Expired - Lifetime DE3482588D1 (de) 1983-11-18 1984-11-09 Androstan-17beta-carbonsaeureester, ein prozess und zwischenprodukte fuer ihre herstellung, kompositionen und methode zur behandlung inflammatorischer zustaende.

Country Status (6)

Country Link
US (1) US4820700A (de)
EP (1) EP0143764B1 (de)
JP (1) JPS60123496A (de)
AT (1) ATE54153T1 (de)
DE (1) DE3482588D1 (de)
SE (1) SE8306370D0 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8501693D0 (sv) * 1985-04-04 1985-04-04 Draco Ab Novel 16,17-acetalsubstituted androstane-17beta-carboxylic acid esters
SE8903914D0 (sv) 1989-11-22 1989-11-22 Draco Ab Oral composition for the treatment of inflammatory bowel diseases
US5643602A (en) * 1989-11-22 1997-07-01 Astra Aktiebolag Oral composition for the treatment of inflammatory bowel disease
HU221584B (hu) * 1993-01-08 2002-11-28 Aktiebolaget Astra Új vastagbél- (colon) vagy csípőbél- (ileum) specifikus, cukortartalmú szteroidszármazékok, ezeket tartalmazó gyógyszerkészítmények és előállításuk
US6166024A (en) * 1995-03-30 2000-12-26 Mayo Foundation For Medical Education And Research Use of topical azathioprine and thioguanine to treat colorectal adenomas
BR9612309A (pt) * 1995-12-29 1999-07-13 Glaxo Group Ltd Composto uso de um composto composição farmacêutica formulação farmacêutica de aerossol combinação e processos para o tratamento de um indivíduo humano ou animal com uma condição anti-inflamatória e/ou alérgica e para a preparação de um composto
CA2260584C (en) * 1998-02-04 2007-07-31 Charlotte-Mecklenburg Hospital D/B/A Carolinas Medical Center Androsterone derivatives for inhibiting dna binding of ap-1 and airway smooth muscle proliferation
JP2010540612A (ja) * 2007-10-04 2010-12-24 アストラゼネカ・アクチエボラーグ グルココルチコイド活性を有するステロイド［３，２−ｃ］ピラゾール化合物
WO2009082342A1 (en) * 2007-12-20 2009-07-02 Astrazeneca Ab Steroid derivatives acting as glucocorticosteroid receptor agonists
WO2009108118A1 (en) * 2008-02-27 2009-09-03 Astrazeneca Ab 16 alpha, 17 alpa-acetal glucocorticosteroidal derivatives and their use
UY32521A (es) * 2009-04-03 2010-10-29 Astrazeneca Ab Combinación para emplear en el tratamiento de enfermedades respiratorias
UY32523A (es) * 2009-04-03 2010-10-29 Astrazeneca Ab Compuestos que tienen actividad agonista del receptor de glucocorticosteroides
UY32525A (es) * 2009-04-03 2010-10-29 Astrazeneca Ab Compuestos que tienen actividad agonista del receptor de glucocorticosteroides
UY32520A (es) * 2009-04-03 2010-10-29 Astrazeneca Ab Compuestos que tienen actividad agonista del receptor de glucocorticoesteroides

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1438940A (en) * 1972-07-19 1976-06-09 Glaxo Lab Ltd 17beta-haloalkoxycarbonyl-17alpha-oxysteroids
CH628355A5 (de) * 1976-02-24 1982-02-26 Ciba Geigy Ag Verfahren zur herstellung neuer androstadien-17beta-carbonsaeuren und ihrer ester und salze.
CH614960A5 (de) * 1976-04-15 1979-12-28 Ciba Geigy Ag
CH634081A5 (en) * 1977-04-13 1983-01-14 Ciba Geigy Ag Process for the preparation of novel androstadiene-17beta-carboxylic acid esters
US4198336A (en) * 1978-04-05 1980-04-15 Syntex (U.S.A.) Inc. Chemical process for preparing androsta-4-ene 17α-carboxylic acids
US4198403A (en) * 1978-04-05 1980-04-15 Syntex (U.S.A.) Inc. 17 Beta-thiocarboxylic acid esters of 4-halo-3-oxoandrost-4-enes

Also Published As

Publication number Publication date
SE8306370D0 (sv) 1983-11-18
EP0143764A1 (de) 1985-06-05
JPS60123496A (ja) 1985-07-02
EP0143764B1 (de) 1990-06-27
US4820700A (en) 1989-04-11
JPH0533714B2 (de) 1993-05-20
ATE54153T1 (de) 1990-07-15

Similar Documents

Publication Publication Date Title
DE3482588D1 (de) Androstan-17beta-carbonsaeureester, ein prozess und zwischenprodukte fuer ihre herstellung, kompositionen und methode zur behandlung inflammatorischer zustaende.
FR2430412A1 (fr) Derives substitues de propanolamine utiles comme medicaments et procede de leur preparation
ZA911403B (en) Derivatives having a naphthalene structure,process for preparing these and pharmaceutical compositions containing them
ATE7897T1 (de) Phenol-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
FR2422637A1 (fr) Nouveaux derives de l'acide 2(4-thio-2-oxo-azetidin-1-yl)-3-methylene-butyrique et procede de preparation
ES479272A1 (es) Un procedimiento para la preparacion de esteres de acidos 17beta-tiocarboxilicos de 4-halo-3-oxoandrost-4-enos.
ATE37872T1 (de) Phenylinden-derivate, ihre salze, und verfahren zu ihrer herstellung.
ATE59387T1 (de) 1,3-dioxan-4-ylalkensaeure.
FR2366311A1 (fr) Procede pour la preparation de steroides polyhalogenes utiles comme medicaments
JPS6025984A (ja) ベンゾチアジアジン誘導体の製造方法
PH24369A (en) Novel 16,17-acetalsubstituted androstane-17b-carboxylic acid esters,pharmaceutical compositions containing said compounds and method of use thereof
DE2754742C2 (de) Verfahren zur Herstellung von substituierten Cephalosporansäureestern
ATE24002T1 (de) Dibenzoxepine, ihre herstellung, diese verbindungen enthaltende zusammensetzungen und ihre verwendung bei der behandlung von allergischen zustaenden.
SU1227628A1 (ru) Способ получени 1-ацетил-5-аминопиразолидинов
FR2566407B1 (fr) Nouveaux derives de l'isoxazoloquinoleine, procede de preparation, application a titre de medicaments, et compositions les renfermant
US3296302A (en) Trichlorovinylsulfenyl chloride and process for the production of trihalovinylsulfenyl chloride
KR880001067B1 (ko) 페닐알칸산 유도체의 제조방법
JPH02178282A (ja) ジアザビシクロアルカン誘導体
ATE15669T1 (de) Derivate der 3-amino-1-heteroaryloxy-propanolklasse, ihre verwendung in der therapie und ein verfahren zu ihrer herstellung.
JPS5610191A (en) Clavulanic acid derivative* its manufacture and composition
TH4052A (th) 16,17-แอเซแทลซับสทิทิวเทด แอนโครสเทน-17(อักษรเคมี)-คาร์บอนซิลิค แอซิด เอสเทอร์ ชนิดใหม่
JPS5618942A (en) Novel terephthalic acid and its preparation
DE3576688D1 (de) Tetrahydropyran-2-yl-alkenyltriazole, diese enthaltende fungizide, verfahren zur herstellung der triazolverbindungen und zwischenprodukte fuer die herstellung.
ES8300338A1 (es) Un procedimiento para la preparacion de derivados de acido fosfinico y fosfonico.
SE8102877L (sv) Nya 16-amino-prostaglandinderivat jemte sett for deras framstellning

Legal Events

Date Code Title Description
8364 No opposition during term of opposition