SE8207092L - Forfarande for framstellning av optiskt aktiva penemer - Google Patents

Forfarande for framstellning av optiskt aktiva penemer

Info

Publication number: SE8207092L
Authority: SE; Sweden
Prior art keywords: procedure; optically active; unsubstituted; hydrogen; formula
Prior art date: 1981-12-11

Application number

SE8207092A

Other languages

English (en)

Other versions

SE458684B (sv

SE8207092D0 (sv

Inventor

M Alpegiani

C Battistini

A Bedeschi

G Franceschi

M Foglio

F Zarini

Original Assignee

Erba Farmitalia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-12-11

Filing date

1982-12-10

Publication date

1983-06-12

1982-12-10 Application filed by Erba Farmitalia filed Critical Erba Farmitalia

1982-12-10 Publication of SE8207092D0 publication Critical patent/SE8207092D0/sv

1983-06-12 Publication of SE8207092L publication Critical patent/SE8207092L/sv

1989-04-24 Publication of SE458684B publication Critical patent/SE458684B/sv

Links

238000000034 method Methods 0.000 title abstract 3
150000002961 penems Chemical class 0.000 title abstract 3
238000004519 manufacturing process Methods 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000006527 (C1-C5) alkyl group Chemical group 0.000 abstract 1
125000002252 acyl group Chemical group 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
239000003242 anti bacterial agent Substances 0.000 abstract 1
230000015572 biosynthetic process Effects 0.000 abstract 1
125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 abstract 1
125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
238000002360 preparation method Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
238000003786 synthesis reaction Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/568—Four-membered rings
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Biochemistry (AREA)
Molecular Biology (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
Communicable Diseases (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Plural Heterocyclic Compounds (AREA)

SE8207092A 1981-12-11 1982-12-10 Foerfarande foer framstaellning av azetidin-2-oner vilka anvaends som mellanprodukter foer framstaellning av penemer SE458684B (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB8137513		1981-12-11

Publications (3)

Publication Number	Publication Date
SE8207092D0 SE8207092D0 (sv)	1982-12-10
SE8207092L true SE8207092L (sv)	1983-06-12
SE458684B SE458684B (sv)	1989-04-24

Family

ID=10526562

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SE8207092A SE458684B (sv)	1981-12-11	1982-12-10	Foerfarande foer framstaellning av azetidin-2-oner vilka anvaends som mellanprodukter foer framstaellning av penemer

Country Status (21)

Country	Link
US (1)	US4508649A (sv)
JP (2)	JPS58126888A (sv)
AT (1)	AT379399B (sv)
AU (1)	AU556854B2 (sv)
BE (1)	BE895322A (sv)
CA (1)	CA1215705A (sv)
CH (1)	CH655504B (sv)
DE (1)	DE3245270C2 (sv)
DK (1)	DK160311C (sv)
FI (1)	FI76347C (sv)
FR (2)	FR2518098B1 (sv)
GB (1)	GB2111496B (sv)
GR (1)	GR77078B (sv)
HU (1)	HU187807B (sv)
IE (1)	IE54513B1 (sv)
IL (1)	IL67434A (sv)
IT (1)	IT1206106B (sv)
NL (2)	NL8204720A (sv)
SE (1)	SE458684B (sv)
SU (1)	SU1389680A3 (sv)
ZA (1)	ZA829063B (sv)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NO831160L (no) *	1982-04-08	1983-10-10	Erba Farmitalia	Fremstilling av substituerte penem-derivater
GB8300295D0 (en) *	1983-01-06	1983-02-09	Erba Farmitalia	Penem esters
GB8321677D0 (en) *	1983-08-11	1983-09-14	Erba Farmitalia	Preparation of penems
JPS62501556A (ja) *	1984-07-13	1987-06-25	メルシャン株式会社	新規２↓−オキソアゼチジン類、その製造方法および応用
GB8713515D0 (en) *	1987-06-10	1987-07-15	Erba Farmitalia	Methoxymethyl compounds
GB8818789D0 (en) *	1988-08-08	1988-09-07	Erba Carlo Spa	Crystalline(5r 6s)-2-carbamoyloxymethyl-6-((1r)-hydroxyethyl)-2-penem-carboxylic acid & pharmaceutical formulation
US5204460A (en) *	1988-11-29	1993-04-20	Takasago International Corporation	Ruthenium catalyzed process for preparing 4-acetoxyazetidinones
DE68920298T2 (de) *	1988-11-29	1995-07-27	Takasago Perfumery Co Ltd	Verfahren zur Herstellung von 4-Acetoxyazetidinonen.
EP0597401A3 (en) *	1992-11-11	1995-07-26	Takeda Chemical Industries Ltd	Preparation of penemes.
JP4512651B2 (ja) *	2008-06-18	2010-07-28	三井金属鉱業株式会社	車両用開閉体の開閉装置

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4348320A (en) *	1976-11-19	1982-09-07	Merck & Co., Inc.	Substituted azetidiones
EP0003960B1 (de) *	1978-02-02	1983-06-29	Ciba-Geigy Ag	6-Substituierte Thia-Azaverbindungen, ihre Herstellung und diese enthaltende pharmazeutische Präparate
AT365594B (de) *	1978-11-24	1982-01-25	Erba Farmitalia	Verfahren zur herstellung von neuen 7-oxo-4-thia1-aza-bicyclo-(3,2,0)heptanderivaten
EP0013067A1 (en) *	1978-12-22	1980-07-09	Beecham Group Plc	Bicyclic beta-lactam antibacterial agents, their use in pharmaceutical compositions, processes for their preparation and intermediates for use in such processes
GB2037277B (en) *	1978-12-22	1983-05-05	Beecham Group Ltd	-lactam antibacterial agents their use in pharmaceutical compositions processes for their preparation and intermediates for use in such processes
AT368506B (de) *	1979-02-24	1982-10-25	Erba Farmitalia	Verfahren zur herstellung von neuen penemcarbonsaeuren und deren salzen
US4269771A (en) *	1979-04-06	1981-05-26	Farmitalia Carlo Erba	Total synthesis of 7-oxo-4-thia-1-azabicyclo-[3,2,0]-heptane-2-carboxyl derivatives useful as β-lactamase inhibitors and antibacterial agents
JPS55153789A (en) *	1979-04-11	1980-11-29	Sankyo Co Ltd	Penem-3-carboxylic acid derivative and its preparation
US4482565A (en) *	1980-02-22	1984-11-13	Farmitalia Carlo Erba S.P.A.	β-Lactam-containing antibacterial agents and β-lactamase inhibitors
GB2079744A (en) *	1980-07-04	1982-01-27	Erba Farmitalia	6-Alkyl-2-functionalized penems

1982
- 1982-12-06 SU SU823522502A patent/SU1389680A3/ru active
- 1982-12-06 AU AU91156/82A patent/AU556854B2/en not_active Ceased
- 1982-12-06 AT AT0443582A patent/AT379399B/de not_active IP Right Cessation
- 1982-12-06 NL NL8204720A patent/NL8204720A/nl not_active Application Discontinuation
- 1982-12-06 US US06/447,187 patent/US4508649A/en not_active Expired - Lifetime
- 1982-12-07 FR FR8220490A patent/FR2518098B1/fr not_active Expired
- 1982-12-07 FI FI824192A patent/FI76347C/sv not_active IP Right Cessation
- 1982-12-07 CA CA000417133A patent/CA1215705A/en not_active Expired
- 1982-12-07 IL IL67434A patent/IL67434A/xx not_active IP Right Cessation
- 1982-12-07 DE DE3245270A patent/DE3245270C2/de not_active Expired - Lifetime
- 1982-12-08 GB GB08235059A patent/GB2111496B/en not_active Expired
- 1982-12-08 IE IE2917/82A patent/IE54513B1/en not_active IP Right Cessation
- 1982-12-08 CH CH714982A patent/CH655504B/de unknown
- 1982-12-09 ZA ZA829063A patent/ZA829063B/xx unknown
- 1982-12-09 IT IT8224650A patent/IT1206106B/it active
- 1982-12-09 JP JP57214750A patent/JPS58126888A/ja active Granted
- 1982-12-09 GR GR70033A patent/GR77078B/el unknown
- 1982-12-10 BE BE0/209711A patent/BE895322A/fr not_active IP Right Cessation
- 1982-12-10 SE SE8207092A patent/SE458684B/sv not_active IP Right Cessation
- 1982-12-10 DK DK551182A patent/DK160311C/da not_active IP Right Cessation
- 1982-12-10 HU HU823997A patent/HU187807B/hu not_active IP Right Cessation
1985
- 1985-06-17 FR FR8509167A patent/FR2567888B1/fr not_active Expired
- 1985-11-27 JP JP60265183A patent/JPS61178987A/ja active Granted
1986
- 1986-02-24 NL NL8600460A patent/NL8600460A/xx not_active Application Discontinuation

Also Published As

Publication number	Publication date
US4508649A (en)	1985-04-02
JPS61178987A (ja)	1986-08-11
DE3245270A1 (de)	1983-06-23
FR2567888A1 (fr)	1986-01-24
GB2111496A (en)	1983-07-06
IT8224650A0 (it)	1982-12-09
NL8204720A (nl)	1983-07-01
JPH0146516B2 (sv)	1989-10-09
FR2518098A1 (fr)	1983-06-17
BE895322A (fr)	1983-06-10
DE3245270C2 (de)	1997-05-15
SE458684B (sv)	1989-04-24
AT379399B (de)	1985-12-27
FR2567888B1 (fr)	1987-04-17
ZA829063B (en)	1983-09-28
AU9115682A (en)	1983-06-16
CH655504B (sv)	1986-04-30
FI76347B (fi)	1988-06-30
FI824192A0 (fi)	1982-12-07
IE822917L (en)	1983-06-11
GR77078B (sv)	1984-09-06
DK160311B (da)	1991-02-25
IL67434A0 (en)	1983-05-15
GB2111496B (en)	1985-05-09
HU187807B (en)	1986-02-28
JPH045033B2 (sv)	1992-01-30
ATA443582A (de)	1985-05-15
DK160311C (da)	1991-07-29
CA1215705A (en)	1986-12-23
AU556854B2 (en)	1986-11-20
SU1389680A3 (ru)	1988-04-15
NL8600460A (nl)	1986-06-02
FI824192L (fi)	1983-06-12
DK551182A (da)	1983-06-12
SE8207092D0 (sv)	1982-12-10
IL67434A (en)	1986-07-31
FI76347C (sv)	1988-10-10
FR2518098B1 (fr)	1986-02-21
JPS58126888A (ja)	1983-07-28
IT1206106B (it)	1989-04-14
IE54513B1 (en)	1989-11-08

Legal Events

Date

Code

Title

Description

1995-01-31

NAL

Patent in force

Ref document number: 8207092-1

Format of ref document f/p: F

2003-02-04

NUG

Patent has lapsed

Publication	Publication Date	Title
ATE33838T1 (de)	1988-05-15	Thiazolidinderivate, ihre herstellung und diese enthaltende zusammensetzungen.
DE3167757D1 (en)	1985-01-24	Dibenz(b,f)(1,4)oxazepine derivatives, process for preparing the same, and pharmaceutical compositions comprising the same
NO943093L (no)	1994-12-09	Fremgangsmåte for fremstilling av clavulansyre
CA2043071A1 (en)	1991-11-24	Heterocyclic compounds
HU906402D0 (en)	1991-04-29	Process for producing tricyclic carbapeneme derivatives an pharmaceutical preparatives containing these compounds as active substance
IE831203L (en)	1983-11-24	Penicillanic acid dioxide prodrug
ATE224T1 (de)	1981-10-15	1,2-dihydro-chinolin-2-on-derivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel.
SE8207092D0 (sv)	1982-12-10	Forfarande for framstellning av optiskt aktiva penemer
FI933903A0 (fi)	1993-09-07	Substituerade cyklohexanderivat, foerfarande foer framstaellning daerav och anvaendning av foereningar foer behandling av sjukdomar
DE69022294D1 (de)	1995-10-19	N-Heteroaryl-purin-6-amine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel.
DE69115526D1 (de)	1996-02-01	2,4-Pyrimidindionderivate und diese enthaltende Arzneimittel
ATE50448T1 (de)	1990-03-15	5-alkyl-1-phenyl-2-piperazinoalkylpyrazolin-3-o - verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel.
AU5157679A (en)	1980-04-17	Isatin derivatives
SE7703000L (sv)	1977-09-18	Forfarande for framstellning av karbostyrilderivat
AU574198B2 (en)	1988-06-30	Penem derivatives
AU658175B2 (en)	1995-04-06	Use of 2-iminothiazolidin-4-one derivatives as novel pharmaceutical active ingredients
ATE37368T1 (de)	1988-10-15	Benzothiazolon-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
ATE14120T1 (de)	1985-07-15	Sulfimine, deren salze und deren herstellung sowie diese verbindungen enthaltende arzneimittel.
CA2053705A1 (en)	1992-04-20	Piperazine derivatives
ATE5408T1 (de)	1983-12-15	Cephalosporine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel.
ATE24487T1 (de)	1987-01-15	Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
FI824479L (fi)	1983-06-29	Foerfarande och mellanprodukt foer framstaellning av farmakologiskt verksamma (1,2)-anellerade 1,4-bensodiazepinfoereningar
SE7910387L (sv)	1980-06-19	7alfa-metoxicefalosporinderivat och forfarande for framstellning derav
ATE81126T1 (de)	1992-10-15	Benzopyrrolidinon-derivate, verfahren zu ihrer herstellung und arzneimittel, die sie enthalten.
ECSP951498A (es)	1996-12-13	Nuevos derivados de pirrocarbazol case ran 4121/15