SE448232B - Fenyletanolaminderivat samt farmaceutisk komposition innehallande nemnda derivat sasom aktiv bestandsdel - Google Patents

Fenyletanolaminderivat samt farmaceutisk komposition innehallande nemnda derivat sasom aktiv bestandsdel

Info

Publication number
SE448232B
SE448232B SE7810613A SE7810613A SE448232B SE 448232 B SE448232 B SE 448232B SE 7810613 A SE7810613 A SE 7810613A SE 7810613 A SE7810613 A SE 7810613A SE 448232 B SE448232 B SE 448232B
Authority
SE
Sweden
Prior art keywords
hydroxy
ethyl
ppm
group
nmr
Prior art date
Application number
SE7810613A
Other languages
English (en)
Swedish (sv)
Other versions
SE7810613L (sv
Inventor
K Imai
K Niigata
T Fujikura
S Hashimoto
T Takenaka
Original Assignee
Yamanouchi Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP12203477A external-priority patent/JPS5473751A/ja
Priority claimed from JP12843677A external-priority patent/JPS5463048A/ja
Priority claimed from JP15535277A external-priority patent/JPS5495544A/ja
Priority claimed from JP7496478A external-priority patent/JPS552639A/ja
Application filed by Yamanouchi Pharma Co Ltd filed Critical Yamanouchi Pharma Co Ltd
Publication of SE7810613L publication Critical patent/SE7810613L/xx
Publication of SE448232B publication Critical patent/SE448232B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/64—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/34—Compounds containing oxirane rings with hydrocarbon radicals, substituted by sulphur, selenium or tellurium atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SE7810613A 1977-10-12 1978-10-11 Fenyletanolaminderivat samt farmaceutisk komposition innehallande nemnda derivat sasom aktiv bestandsdel SE448232B (sv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP12203477A JPS5473751A (en) 1977-10-12 1977-10-12 Phenyl ethanolamine derivatives and their preparation
JP12843677A JPS5463048A (en) 1977-10-26 1977-10-26 Novel phenyl ethanolamine derivatives and their preparation
JP15535277A JPS5495544A (en) 1977-12-23 1977-12-23 Phenylethanolamine derivative and its preparation
JP7496478A JPS552639A (en) 1978-06-21 1978-06-21 Phenylethanolamine derivative and its preparation

Publications (2)

Publication Number Publication Date
SE7810613L SE7810613L (sv) 1979-04-13
SE448232B true SE448232B (sv) 1987-02-02

Family

ID=27465764

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7810613A SE448232B (sv) 1977-10-12 1978-10-11 Fenyletanolaminderivat samt farmaceutisk komposition innehallande nemnda derivat sasom aktiv bestandsdel

Country Status (16)

Country Link
US (1) US4217305A (de)
AT (1) AT363457B (de)
AU (1) AU526715B2 (de)
CA (1) CA1147342A (de)
CH (1) CH639948A5 (de)
DE (1) DE2843016A1 (de)
DK (1) DK168484B1 (de)
ES (2) ES474149A1 (de)
FR (1) FR2405931A1 (de)
GB (1) GB2006772B (de)
GR (1) GR65337B (de)
IT (1) IT1160853B (de)
NO (1) NO147148C (de)
PT (1) PT68624A (de)
SE (1) SE448232B (de)
SU (2) SU982537A3 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55124742A (en) * 1979-03-20 1980-09-26 Kyowa Hakko Kogyo Co Ltd Novel aminoalcohol derivative
US4206125A (en) * 1979-05-04 1980-06-03 Richardson-Merrell Inc. 5-[2-[(2,3-Dihydro-1,4-benzodioxan-2-ylmethyl)amino]-1-hydroxyethyl]-2-hydroxybenzoic acid derivatives
DD202692A5 (de) * 1979-12-04 1983-09-28 Ciba Geigy Verfahren zur herstellung neuer derivate des 2-amino-aethanols
JPS56110665A (en) * 1980-02-08 1981-09-01 Yamanouchi Pharmaceut Co Ltd Sulfamoyl-substituted phenetylamine derivative and its preparation
US4558156A (en) * 1980-02-08 1985-12-10 Yamanouchi Pharmaceutical Co., Ltd. Sulfamoyl-substituted phenethylamine derivatives
US5391825A (en) * 1980-02-08 1995-02-21 Yamanouchi Pharmaceutical Co., Ltd. Sulfamoyl substituted phenethylamine intermediates
DE3128117A1 (de) * 1980-07-29 1982-03-11 Yamanouchi Pharmaceutical Co., Ltd., Tokyo Neue phenyl-aethylaminderivate, verfahren zu ihrer herstellung
CA1219865A (en) * 1982-05-14 1987-03-31 Leo Alig Aziridine phenethanolamine derivatives
PT78388B (en) * 1983-04-12 1986-09-15 Smithkline Beckman Corp Dopamine-beta-hydroxylase inhibitors
JPS6051106A (ja) * 1983-08-31 1985-03-22 Yamanouchi Pharmaceut Co Ltd 塩酸アモスラロ−ル持続性製剤
EP0162404B1 (de) * 1984-05-15 1988-08-24 Seitetsu Kagaku Co., Ltd. Verfahren zur Herstellung von 2-Alkyl-5-halobenzensulfonamiden
US4678855A (en) * 1985-10-09 1987-07-07 Merck & Co., Inc. Substituted benzenesulfonamides
JPS62114952A (ja) * 1985-11-13 1987-05-26 Yamanouchi Pharmaceut Co Ltd 置換フエネチルアミン誘導体の製造法
IE883400L (en) * 1987-11-13 1989-05-13 Fuisz Technologies Ltd Phenethanolamine derivatives
WO1993024121A1 (en) * 1992-05-22 1993-12-09 Senju Pharmaceutical Co., Ltd. Remedy for glaucoma
FR2737494B1 (fr) * 1995-08-04 1997-08-29 Synthelabo Derives de benzenesulfonamide, leur preparation et leur application en therapeutique
KR100395280B1 (ko) * 1996-01-10 2004-06-04 아사히 가세이 가부시키가이샤 신규한3환성화합물및그를함유하는의약조성물
EP1075486A1 (de) * 1998-05-06 2001-02-14 Duke University Verfahren zur behandlung von syndromen der niere und der unteren harnwege
FR2791675B1 (fr) * 1999-03-30 2001-05-04 Synthelabo Derives de n-[2-(4-aminophenyl) ethyl] -2,3-dihydro-1,4- benzodioxinne-2-methanamine, leur preparation et leur application en therapeutique
US6835853B2 (en) * 2001-10-31 2004-12-28 Synthon Bv Process for resolution of tamsulosin and compounds, compositions, and processes associated therewith
OA12905A (en) 2002-08-19 2006-10-13 Pfizer Prod Inc Combination therapy for hyperproliferative diseases.
KR20060021870A (ko) 2003-05-30 2006-03-08 랜박시 래보러터리스 리미티드 치환된 피롤 유도체와 ｈｍｇ―ｃｏ 억제제로서의 이의용도
KR100596373B1 (ko) 2003-12-09 2006-07-04 씨제이 주식회사 광학적으로 순수한 펜에틸 아민 유도체의 제조방법
ES2328384T3 (es) * 2004-11-23 2009-11-12 Warner-Lambert Company Llc Derivados del acido 7-(2h-pirazol-3-il)-3,5-dihidroxi-heptanoico como inhibidores de hmg co-a reductasa para el tratamiento de la lipidemia.
GT200600381A (es) 2005-08-25 2007-03-28 Compuestos organicos
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
WO2007054896A1 (en) 2005-11-08 2007-05-18 Ranbaxy Laboratories Limited Process for (3r, 5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
EP2026766A1 (de) 2006-05-17 2009-02-25 Synthon B.V. Tabletten-zusammensetzung mit verlängerter freisetzung von tamsulosin
US8404896B2 (en) 2006-12-01 2013-03-26 Bristol-Myers Squibb Company N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as CETP inhibitors for the treatment of atherosclerosis and cardiovascular diseases
US8465770B2 (en) * 2008-12-24 2013-06-18 Synthon Bv Low dose controlled release tablet
CN102050766B (zh) * 2009-11-03 2013-08-07 安徽省新星药物开发有限责任公司 一种盐酸氨磺洛尔的合成方法
JP2016516804A (ja) 2013-04-17 2016-06-09 ファイザー・インク 心血管疾患を治療するためのｎ−ピペリジン−３−イルベンズアミド誘導体
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
JOP20210193A1 (ar) 2019-01-18 2023-01-30 Astrazeneca Ab مثبطات pcsk9 وطرق استخدامها

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3701808A (en) * 1967-12-21 1972-10-31 Allen & Hanburys Ltd Phenylethanolamines
GB1266058A (de) 1969-07-08 1972-03-08
GB1321701A (en) 1969-10-01 1973-06-27 Continental Pharma Amino-alcohols their salts and process for prepairing the same
US3711545A (en) * 1971-02-23 1973-01-16 Smith Kline French Lab Alpha-aminoalkyl-4-hydroxy-3-sulfamoylaminobenzyl alcohols
DE2115926C3 (de) * 1971-04-01 1978-05-03 C.H. Boehringer Sohn, 6507 Ingelheim 1 -(4-Hydroxy-3-dimethylaminosuIfamidophenyI)-2-aminoäthanderivate, Verfahren zu ihrer Herstellung und diese enthaltende Mittel
US4034112A (en) * 1973-06-22 1977-07-05 Imperial Chemical Industries Limited Ethanolamine derivatives having β-adrenergic blocking activity
US3860647A (en) * 1973-08-20 1975-01-14 Smithkline Corp {60 -Aminomethyl-4-hydroxy-3-sulfamyl-benzyl alcohols and 4-hydroxy-3-sulfamyl phenethylamines
DK31578A (da) * 1977-02-03 1978-08-04 Allen & Hanburys Ltd Fremgangsmaade til fremstilling af benzenderivater
GB1593651A (en) * 1977-02-03 1981-07-22 Allen & Hanburys Ltd Amides

Also Published As

Publication number Publication date
CA1147342A (en) 1983-05-31
DK168484B1 (da) 1994-04-05
NO147148C (no) 1983-02-09
GR65337B (en) 1980-08-18
AU526715B2 (en) 1983-01-27
IT1160853B (it) 1987-03-11
PT68624A (en) 1978-11-01
NO783442L (no) 1979-04-18
NO147148B (no) 1982-11-01
SU932982A3 (ru) 1982-05-30
GB2006772B (en) 1982-02-03
US4217305A (en) 1980-08-12
ATA731778A (de) 1981-01-15
AT363457B (de) 1981-08-10
SU982537A3 (ru) 1982-12-15
ES474149A1 (es) 1979-10-16
AU4064278A (en) 1980-04-17
IT7869350A0 (it) 1978-10-11
DE2843016C2 (de) 1988-10-13
DE2843016A1 (de) 1979-04-26
FR2405931B1 (de) 1982-11-19
SE7810613L (sv) 1979-04-13
FR2405931A1 (fr) 1979-05-11
DK452178A (da) 1979-04-13
GB2006772A (en) 1979-05-10
CH639948A5 (de) 1983-12-15
ES481549A1 (es) 1980-04-01

Similar Documents

Publication Publication Date Title
SE448232B (sv) Fenyletanolaminderivat samt farmaceutisk komposition innehallande nemnda derivat sasom aktiv bestandsdel
US4034009A (en) 4-Ureido-2-acyl phenoxypropanolamine
DE60208355T2 (de) 2-amino-propanol derivate
US3261859A (en) Basically substituted phenyl acetonitrile compounds
FI85263C (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara polykarbocykliska aromatiska alkanolderivat och nya mellanprodukter.
EP0222475B1 (de) Sulfonylharnstoffe zur Tumorbekämpfung
EP0166615B1 (de) Benzensulfonamid-Derivate
DE2645710A1 (de) Phenoxy-amino-propanole und verfahren zu ihrer herstellung
EP0004532B1 (de) 1-Aryloxy-3-nitratoalkylamino-2-propanole, Verfahren zu ihrer Herstellung und ihre pharmazeutischen Zubereitungen
SE411897B (sv) Forfarande for framstellning av nya 1-aryloxi-2-hydroxi-3-alkinylaminopropaner
DD295353A5 (de) Verfahren zur herstellung von benzonitrilderivaten
US2964560A (en) Orally effective compounds for treating diabetes and a process of making same
CZ263692A3 (en) Thiadiazinones, process of their preparation and pharmaceutical compositions based thereon
FI62060B (fi) Foerfarande foer framstaellning av beta-blockerande substituerad 2-hydroxi-3-(2-acyl-4-ureido-fenoxi)-propylaminderivat
EP0113910B1 (de) Isocarbostyrilderivate, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitungen, die sie enthalten
JPS5950671B2 (ja) フェニルエタノ−ルアミン誘導体およびその製造法
US4110472A (en) Derivatives of 1-(disubstituted phenoxy)-3-amino-2-hydroxypropanes
EP0011747B1 (de) Aminopropanolderivate des 6-Hydroxy-2,3,4,5-tetrahydro-1H-1-benzazepin-2-ons, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
IL44003A (en) 1-(p-(alkylthioalkoxy)phenoxy)-3-(substituted amino)-2-propanols their preparation and pharmaceutical compositions containing them
KR820000508B1 (ko) 페닐에탄올 아민 유도체의 제조방법
US4101579A (en) Phenethanolamine ethers
KR820000521B1 (ko) 페닐에탄올아민 유도체의 제조 방법
EP0005192B1 (de) Alkylaminopropanolderivate von 3-Alkyl-5-(2-hydroxystyryl)-isoxazolen, Verfahren zu ihrer Herstellung und diese enthaltende therapeutische Mittel
KR820000522B1 (ko) 페닐에탄올아민 유도체의 제조방법
US4868315A (en) Novel aryloxycycloalkanolaminoalkylene aryl ketones

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 7810613-5

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 7810613-5

Format of ref document f/p: F