SE445219B - 1,4-dihydropyridinderivat, forfarande for framstellning derav samt farmaceutisk komposition - Google Patents

1,4-dihydropyridinderivat, forfarande for framstellning derav samt farmaceutisk komposition

Info

Publication number
SE445219B
SE445219B SE7910188A SE7910188A SE445219B SE 445219 B SE445219 B SE 445219B SE 7910188 A SE7910188 A SE 7910188A SE 7910188 A SE7910188 A SE 7910188A SE 445219 B SE445219 B SE 445219B
Authority
SE
Sweden
Prior art keywords
compound
formula
czhs
czus
meaning
Prior art date
Application number
SE7910188A
Other languages
English (en)
Swedish (sv)
Other versions
SE7910188L (sv
Inventor
P Neumann
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of SE7910188L publication Critical patent/SE7910188L/xx
Publication of SE445219B publication Critical patent/SE445219B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
SE7910188A 1978-12-18 1979-12-11 1,4-dihydropyridinderivat, forfarande for framstellning derav samt farmaceutisk komposition SE445219B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1283578A CH639659A5 (de) 1978-12-18 1978-12-18 Neue 1,4-dihydropyridinderivate, deren herstellung und verwendung.

Publications (2)

Publication Number Publication Date
SE7910188L SE7910188L (sv) 1980-06-19
SE445219B true SE445219B (sv) 1986-06-09

Family

ID=4386824

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7910188A SE445219B (sv) 1978-12-18 1979-12-11 1,4-dihydropyridinderivat, forfarande for framstellning derav samt farmaceutisk komposition

Country Status (18)

Country Link
JP (1) JPS5583783A (ja)
AU (1) AU536055B2 (ja)
BE (1) BE880591A (ja)
CH (1) CH639659A5 (ja)
CY (1) CY1321A (ja)
DE (1) DE2949491A1 (ja)
FR (1) FR2444681A1 (ja)
GB (2) GB2103203B (ja)
HK (1) HK16086A (ja)
IE (1) IE49496B1 (ja)
IT (1) IT1164097B (ja)
KE (1) KE3593A (ja)
MY (1) MY8500130A (ja)
NL (2) NL193066C (ja)
NZ (1) NZ192422A (ja)
SE (1) SE445219B (ja)
SG (1) SG97585G (ja)
ZA (1) ZA796842B (ja)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3022030A1 (de) * 1980-06-12 1981-12-17 Bayer Ag, 5090 Leverkusen 4-thiazol- bzw. 4-imidazol-substituierte, 1,4-dihydropyridine, verfahren zu deren herstellung sowie diese enthaltende arzneimittel
CH655658B (ja) * 1980-09-18 1986-05-15
DE3269219D1 (en) * 1981-11-17 1986-03-27 Fisons Plc Dihydropyridines, methods for their production and their formulation and use as pharmaceuticals
ZA83959B (en) * 1982-03-10 1984-09-26 Sandoz Ltd 1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
US4414213A (en) * 1982-03-22 1983-11-08 Mead Johnson & Company Dihydropyridyl cyclic imidate esters and their pharmaceutical use
IL68975A (en) * 1982-06-15 1987-01-30 Sandoz Ag 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydropyridine-3,5-dicarboxylic acid ester derivatives in optically active form,their preparation and pharmaceutical compositions containing them
FR2528431B1 (fr) * 1982-06-15 1986-01-10 Sandoz Sa Nouveaux derives de la 1,4-dihydropyridine, leur preparation et leur utilisation comme medicaments
JPS5978186A (ja) * 1982-10-27 1984-05-04 Yoshitomi Pharmaceut Ind Ltd 1,4−ジヒドロピリジン−3,5−ジカルボン酸エステル誘導体
US4794111A (en) * 1984-05-23 1988-12-27 Bayer Aktiengesellschaft Dihydropyridine preparations containing β-blockers
HU198844B (en) * 1984-06-14 1989-12-28 Sandoz Ag Process for producing new galenic pharmaceutical composition ensuring retarded release of active ingredient
US5260321A (en) * 1984-11-12 1993-11-09 Sandoz Ltd. Use of 1,4-dihydropyridine derivatives and combinations thereof with calcitonins
NL194822C (nl) * 1985-10-01 2003-04-03 Novartis Ag Preparaat voor orale toediening met geregelde afgifte en werkwijze voor de bereiding ervan.
DE3542794A1 (de) * 1985-12-04 1987-06-11 Bayer Ag Antihypertensives kombinationspraeparat
GB8626217D0 (en) * 1986-11-03 1986-12-03 Sandoz Ltd Pharmaceutical compositions
US4816263A (en) * 1987-10-02 1989-03-28 Alza Corporation Dosage form for treating cardiovascular diseases comprising isradipine
KR940003492B1 (ko) * 1988-10-27 1994-04-23 주식회사 유한양행 1,4-디하이드로피리딘유도체 및 그의 제조방법
DE4222770A1 (de) * 1992-07-10 1994-01-13 Bayer Ag Lichtaktivierbare 1-(2-Nitrobenzyl)-substituierte 1,4-Dihydropyridine
WO2003079972A2 (en) 2002-02-22 2003-10-02 New River Parmaceuticals Inc. Active agent delivery systems and methods for protecting and administering active agents
AU2003269482A1 (en) * 2003-09-10 2005-03-29 Shasun Chemicals And Drugs Limited Process for the manufacture of 2,1,3-benzoxadiazole-4-carboxaldehyde
CN103613584B (zh) * 2013-11-27 2016-04-27 沈阳药科大学 一种伊拉地平合成产物后处理的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670824C3 (de) * 1967-03-20 1978-08-03 Bayer Ag, 5090 Leverkusen 1,4-Dihydropyridin-33-dicarbonsäurealkylester
FR2320750A1 (fr) * 1975-08-12 1977-03-11 Hexachimie Dihydro-1,4 pyridines et leur application therapeutique
DE2616991A1 (de) * 1976-04-17 1977-10-27 Bayer Ag Heterocyclisch-substituierte schwefelhaltige dihydropyridine, mehrere verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
JPS5373327A (en) * 1976-12-13 1978-06-29 Matsushita Electric Ind Co Ltd Power source system
DK149855C (da) * 1977-06-20 1987-04-21 Sandoz Ag Analogifremgangsmaade til fremstilling af 1,4-dihydropyridinderivater

Also Published As

Publication number Publication date
DE2949491A1 (de) 1980-06-26
CH639659A5 (de) 1983-11-30
GB2037766B (en) 1983-02-16
CY1321A (en) 1986-06-27
ZA796842B (en) 1981-07-29
HK16086A (en) 1986-03-14
NL7909024A (nl) 1980-06-20
IT7951095A0 (it) 1979-12-14
JPH0369910B2 (ja) 1991-11-05
AU536055B2 (en) 1984-04-19
NZ192422A (en) 1982-09-14
NL193066C (nl) 1998-09-08
NL193066B (nl) 1998-05-06
GB2103203A (en) 1983-02-16
GB2103203B (en) 1983-06-08
NL990014I1 (nl) 1999-07-01
BE880591A (fr) 1980-06-13
GB2037766A (en) 1980-07-16
IE792445L (en) 1980-06-18
IE49496B1 (en) 1985-10-16
AU5389679A (en) 1980-06-26
SE7910188L (sv) 1980-06-19
DE2949491C2 (ja) 1988-10-27
FR2444681B1 (ja) 1982-10-29
JPS5583783A (en) 1980-06-24
MY8500130A (en) 1985-12-31
KE3593A (en) 1986-02-07
FR2444681A1 (fr) 1980-07-18
SG97585G (en) 1986-07-18
IT1164097B (it) 1987-04-08

Similar Documents

Publication Publication Date Title
SE445219B (sv) 1,4-dihydropyridinderivat, forfarande for framstellning derav samt farmaceutisk komposition
US4466972A (en) Benzoxadiazoles and benzothiadiazoles, their preparation and pharmaceutical compositions containing them
CS228506B2 (en) Method for the production of optical active ester of 1,4-dihydropyridincarboxyl acid
KR960009570B1 (ko) 이미다졸린 유도체 및 그의 제조방법
FI64938C (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara bensoxa- och bensotiadiazolyl-1,4-dihydropyridinderivat
IT9021075A1 (it) Derivati acidi benzoici sostituiti ad attivita' cardiovascolare
GB1563989A (en) Sulfonamides
CA1255660A (en) Tetrahydrothienopyridines, a process for their preparation and their use as medicaments
US4874773A (en) 3-Aminocarbonyl-1,4-dihydropyridine-5-carboxylic acid compounds, and pharmaceutical composition containing the same
McFarland et al. Novel anthelmintic agents. IV. Noncyclic amidines related to pyrantel
EP0856513A2 (de) Thalidomidanaloge Verbindungen aus der Klasse der Piperidin-2,6-Dione
CS200499B2 (en) Process for preparing isobutylestere of 2,6-dimethyl-3-methoxycarbonyl-4-/2-nitrophenyl/1,4-dihydropyridin-5-carboxylic acid
US4567271A (en) Benzoxadiazoles and benzothiadiazoles
JPS6289662A (ja) 1,4−ジヒドロピリジン誘導体
CH660190A5 (de) 1,4-dihydropyridin-derivate, verfahren zur ihrer herstellung und sie enthaltende pharmazeutische zubereitungen.
Walter et al. Derivatives of 3-piperidinol as central stimulants
US4500708A (en) Benzothiazine derivatives
JPS5885884A (ja) 4−(2,1,3−ベンゾキサジアゾル−4−イル)−1,4−ジヒドロピリダジン類およびそれを含む薬学的組成物
JPS6352031B2 (ja)
EP0280239B1 (en) 1,4-dihydropyridine derivatives, production and use thereof
IE49497B1 (en) 1,4-dihydropyridines,their preparation and pharmaceutical compositions containing them
EP0018134B1 (en) Dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions containing them
EP0301245A2 (de) 3-Sulfonyl-3,7-diazabicyclo-(3,3,1)nonan-Verbindungen sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
ATE66677T1 (de) Isomere von derivaten der dihydropyridin-3,5dicarboxyls|ureester, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen.
NL8105035A (nl) 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-pyridinederivaten, werkwijzen voor hun bereiding en van farmaceutische preparaten die ze bevatten.

Legal Events

Date Code Title Description
SPCF Application for supplementary protection certificate filed

Free format text: 7910188

NAL Patent in force

Ref document number: 7910188-7

Format of ref document f/p: F

SPCG Supplementary protection certificate granted

Free format text: 9490162, 900907, EXPIRES: 20040102

SPCG Supplementary protection certificate granted

Free format text: 9490162, 900907, EXPIRES: 20041211

NUG Patent has lapsed

Ref document number: 7910188-7

Format of ref document f/p: F