SE0100902D0 - Compounds - Google Patents
CompoundsInfo
- Publication number
- SE0100902D0 SE0100902D0 SE0100902A SE0100902A SE0100902D0 SE 0100902 D0 SE0100902 D0 SE 0100902D0 SE 0100902 A SE0100902 A SE 0100902A SE 0100902 A SE0100902 A SE 0100902A SE 0100902 D0 SE0100902 D0 SE 0100902D0
- Authority
- SE
- Sweden
- Prior art keywords
- compounds
- inhibitors
- mmp12
- useful
- formula
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
- C07D233/78—Radicals substituted by oxygen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Otolaryngology (AREA)
- Psychiatry (AREA)
- Ophthalmology & Optometry (AREA)
- Vascular Medicine (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Oncology (AREA)
- Gastroenterology & Hepatology (AREA)
Priority Applications (117)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0100902A SE0100902D0 (sv) | 2001-03-15 | 2001-03-15 | Compounds |
CZ20032502A CZ20032502A3 (cs) | 2001-03-15 | 2002-03-13 | Inhibitory metalloproteinasy |
DE60238794T DE60238794D1 (de) | 2001-03-15 | 2002-03-13 | Hydantoinderivate als MMP-Inhibitoren |
PL02364714A PL364714A1 (en) | 2001-03-15 | 2002-03-13 | Metalloproteinase inhibitors |
US10/471,808 US20040147573A1 (en) | 2001-03-15 | 2002-03-13 | Metalloproteinase inhibitors |
ES02704037T ES2352246T3 (es) | 2001-03-15 | 2002-03-13 | Inhibidores de metaloproteinasas. |
AT02704037T ATE484496T1 (de) | 2001-03-15 | 2002-03-13 | Metalloproteinaseinhibitoren |
HU0400206A HUP0400206A3 (en) | 2001-03-15 | 2002-03-13 | Imidazolidindion derivatives having metalloproteinase inhibitor effect a their use for preparation of pharmaceutical compositions and pharmaceutical compositions containing them |
RU2003127733/04A RU2285695C2 (ru) | 2001-03-15 | 2002-03-13 | Производные имидазолидин-2,4-диона, содержащие их фармацевтические композиции и их применение |
EEP200300449A EE200300449A (et) | 2001-03-15 | 2002-03-13 | Metalloproteinaasi inhibiitorid |
CZ20032500A CZ20032500A3 (cs) | 2001-03-15 | 2002-03-13 | Inhibitory metalloproteinasy |
EEP200300439A EE200300439A (et) | 2001-03-15 | 2002-03-13 | Metalloproteinaasi inhibiitorid |
CNA028100417A CN1509275A (zh) | 2001-03-15 | 2002-03-13 | 金属蛋白酶抑制剂 |
AU2002237632A AU2002237632B2 (en) | 2001-03-15 | 2002-03-13 | Metalloproteinase inhibitors |
NZ528140A NZ528140A (en) | 2001-03-15 | 2002-03-13 | Metalloproteinase inhibitors |
BR0207983-6A BR0207983A (pt) | 2001-03-15 | 2002-03-13 | Inibidores de metaloproteinase |
CNB028097882A CN1304377C (zh) | 2001-03-15 | 2002-03-13 | 金属蛋白酶抑制剂 |
RU2003127732/04A RU2003127732A (ru) | 2001-03-15 | 2002-03-13 | Ингибиторы металлопротеиназ |
MYPI20020910A MY136789A (en) | 2001-03-15 | 2002-03-13 | Metalloproteinase inhibitors |
IL15757002A IL157570A0 (en) | 2001-03-15 | 2002-03-13 | Metalloproteinase inhibitors |
MYPI20020904A MY136141A (en) | 2001-03-15 | 2002-03-13 | Novel hydantoin derivatives and pharmaceutical compositions useful as metalloproteinase inhibitors |
SK1092-2003A SK287834B6 (sk) | 2001-03-15 | 2002-03-13 | Metalloproteinase inhibitors |
DE60213216T DE60213216T2 (de) | 2001-03-15 | 2002-03-13 | Metalloproteinaseinhibitoren |
PCT/SE2002/000475 WO2002074750A1 (en) | 2001-03-15 | 2002-03-13 | Metalloproteinase inhibitors |
BR0208104-0A BR0208104A (pt) | 2001-03-15 | 2002-03-13 | Inibidores de metaloproteinase |
BR0208105-9A BR0208105A (pt) | 2001-03-15 | 2002-03-13 | Inibidores de metaloproteinase |
CNB02810093XA CN1269804C (zh) | 2001-03-15 | 2002-03-13 | 金属蛋白酶抑制剂 |
CN2006101061525A CN1962641B (zh) | 2001-03-15 | 2002-03-13 | 金属蛋白酶抑制剂 |
KR1020037011987A KR100886315B1 (ko) | 2001-03-15 | 2002-03-13 | 메탈로프로테이나제 억제제 |
BR0207984-4A BR0207984A (pt) | 2001-03-15 | 2002-03-13 | Inibidores de metaloproteinase |
MXPA03008177A MXPA03008177A (es) | 2001-03-15 | 2002-03-13 | Inhibidores de metaloproteinasa.. |
AU2002237626A AU2002237626B2 (en) | 2001-03-15 | 2002-03-13 | Metalloproteinase inhibitors |
NZ528106A NZ528106A (en) | 2001-03-15 | 2002-03-13 | Metalloproteinase inhibitors |
JP2002573776A JP2004527515A (ja) | 2001-03-15 | 2002-03-13 | メタロプロテイナーゼ阻害剤 |
SI200230386T SI1370556T1 (sl) | 2001-03-15 | 2002-03-13 | Metaloproteinazni inhibitorji |
EEP200300451A EE05364B1 (et) | 2001-03-15 | 2002-03-13 | Metalloproteinaasi inhibiitorid |
IL15765202A IL157652A0 (en) | 2001-03-15 | 2002-03-13 | Metalloproteinase inhibitors |
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