RU2006143081A - WATER-SOLUBLE MEDICINAL COMPOSITION AND METHOD FOR PRODUCING IT - Google Patents
WATER-SOLUBLE MEDICINAL COMPOSITION AND METHOD FOR PRODUCING IT Download PDFInfo
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- RU2006143081A RU2006143081A RU2006143081/15A RU2006143081A RU2006143081A RU 2006143081 A RU2006143081 A RU 2006143081A RU 2006143081/15 A RU2006143081/15 A RU 2006143081/15A RU 2006143081 A RU2006143081 A RU 2006143081A RU 2006143081 A RU2006143081 A RU 2006143081A
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- RU
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- water
- arabinogalactan
- drug substance
- soluble
- drug
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
1. Водорастворимая лекарственная композиция с повышенной фармакологической активностью, состоящая из малорастворимых в воде лекарственных субстанций в виде водорастворимых межмолекулярных комплексов с арабиногалактаном.2. Способ получения водорастворимой лекарственной композиции по п.1, включающий смешение комплексообразователя с исходной порошкообразной лекарственной субстанцией, отличающийся тем, что в качестве комплексообразователя используют арабиногалактан, смесь малорастворимой в воде лекарственной субстанции с арабиногалактаном подвергают механической обработке.3. Способ по п.2, отличающийся тем, что механическую обработку проводят путем ударно-истирающих воздействий.4. Способ по п.2, отличающийся тем, что малорастворимую в воде лекарственную субстанцию и арабиногалактан берут, преимущественно, в соотношении от 1:5 до 1:20 по весу, соответственно.5. Способ по п.2, отличающийся там, что смесь малорастворимой в воде лекарственной субстанции и арабиногалактана подвергают обработке путем ударно-истирающих механических воздействий до исчезновения кристаллической фазы лекарственной субстанции.1. A water-soluble drug composition with increased pharmacological activity, consisting of poorly water soluble drug substances in the form of water-soluble intermolecular complexes with arabinogalactan. 2. A method for producing a water-soluble drug composition according to claim 1, comprising mixing a complexing agent with an initial powdered drug substance, characterized in that arabinogalactan is used as a complexing agent, a mixture of a slightly soluble drug substance with arabinogalactan is subjected to mechanical treatment. The method according to claim 2, characterized in that the machining is carried out by impact-abrasion. The method according to claim 2, characterized in that the water-insoluble drug substance and arabinogalactan are taken, preferably, in a ratio of from 1: 5 to 1:20 by weight, respectively. The method according to claim 2, characterized in that the mixture of a slightly soluble in water drug substance and arabinogalactan is subjected to treatment by shock-abrasion mechanical effects until the crystalline phase of the drug substance disappears.
Claims (5)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2006143081/15A RU2337710C2 (en) | 2006-12-05 | 2006-12-05 | Water-soluble medicinal composition and method of production thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| RU2006143081/15A RU2337710C2 (en) | 2006-12-05 | 2006-12-05 | Water-soluble medicinal composition and method of production thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2006143081A true RU2006143081A (en) | 2008-06-20 |
| RU2337710C2 RU2337710C2 (en) | 2008-11-10 |
Family
ID=40230496
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2006143081/15A RU2337710C2 (en) | 2006-12-05 | 2006-12-05 | Water-soluble medicinal composition and method of production thereof |
Country Status (1)
| Country | Link |
|---|---|
| RU (1) | RU2337710C2 (en) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2451680C1 (en) | 2011-02-21 | 2012-05-27 | Общество С Ограниченной Ответственностью "Научно-Исследовательская Компания "Медбиофарм" | Clatrate complex of cyclodextrine or arabinogalactane with 9-phenyl-symm-octahydroselenoxantene, its production method (versions), pharmaceutical composition and medication |
| RU2477143C1 (en) * | 2011-10-26 | 2013-03-10 | Федеральное государственное автономное образовательное учреждение высшего профессионального образования "Северо-Восточный федеральный университет имени М.К. Аммосова" | Biologically active additive of actoprotective, adaptogenic action of herbal raw materials and method for preparing it |
| RU2568883C2 (en) * | 2013-03-28 | 2015-11-20 | Общество с ограниченной ответственностью "Вита эст про" | Gynostemma pentaphyllum composition with high pharmacological activity |
| RU2545797C1 (en) * | 2013-10-03 | 2015-04-10 | Федеральное государственное бюджетное учреждение науки Институт химии твердого тела и механохимии Сибирского отделения Российской академии наук (ИХТТМ СО РАН) | Albendazole-based composition with anti-opisthorchosis pharmacological activity |
| RU2541153C1 (en) * | 2013-12-04 | 2015-02-10 | Федеральное государственное бюджетное учреждение науки Институт химии твердого тела и механохимии Сибирского отделения Российской академии наук (ИХТТМ СО РАН) | Dipropionate betulin composition |
| RU2609734C2 (en) * | 2015-03-19 | 2017-02-02 | Федеральное бюджетное учреждение науки "Государственный научный центр вирусологии и биотехнологии "Вектор" (ФБУН ГНЦ ВБ "Вектор") | Pneumatic generator of liquid aerosol particles and aqueous solution of hydrophobic compounds of vegetal origin in form of aerosol of submicron particles, obtained using said generator |
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2006
- 2006-12-05 RU RU2006143081/15A patent/RU2337710C2/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| RU2337710C2 (en) | 2008-11-10 |
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| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | The patent is invalid due to non-payment of fees |
Effective date: 20191206 |