RU2006125434A - Пептиды, обладающие асе-ингибирующим действием - Google Patents
Пептиды, обладающие асе-ингибирующим действием Download PDFInfo
- Publication number
- RU2006125434A RU2006125434A RU2006125434/13A RU2006125434A RU2006125434A RU 2006125434 A RU2006125434 A RU 2006125434A RU 2006125434/13 A RU2006125434/13 A RU 2006125434/13A RU 2006125434 A RU2006125434 A RU 2006125434A RU 2006125434 A RU2006125434 A RU 2006125434A
- Authority
- RU
- Russia
- Prior art keywords
- food product
- tripeptide
- hrp
- angiotensin
- ace
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J3/00—Working-up of proteins for foodstuffs
- A23J3/30—Working-up of proteins for foodstuffs by hydrolysis
- A23J3/32—Working-up of proteins for foodstuffs by hydrolysis using chemical agents
- A23J3/34—Working-up of proteins for foodstuffs by hydrolysis using chemical agents using enzymes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/18—Peptides; Protein hydrolysates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/005—Enzyme inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nutrition Science (AREA)
- Epidemiology (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Peptides Or Proteins (AREA)
- Cosmetics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Claims (9)
1. Применение трипептида ХРР, в котором Х=С, М, S, Т или К, и/или его солей для получения ингибитора фермента, катализирующего превращение ангиотензина.
2. Применение по п.1, где Х=С, М, S или Т.
3. Применение по п.2, где Х=М, S или Т.
4. Применение по любому из пунктов 1-3, в котором ингибитор фермента, катализирующего превращение ангиотензина, является функциональным пищевым продуктом.
5. Пищевой продукт, пригодный для снижения кровяного давления у людей, содержащий 5 мг/г или более ХРР, где Х=С, М, S, Т, К, Р или А.
6. Пищевой продукт по п.5, содержащий 10 мг/г или более ХРР.
7. Пищевой продукт по п.5 или 6, где Х=С, М, S или Т.
8. Пищевой продукт по п.7, где Х=М, S или Т.
9. Способ приготовления пищевого продукта, содержащего ХРР, где Х=С, М, S, Т или К, включающий следующие стадии:
(а) ферментативный гидролиз субстрата, содержащего белок, имеющий последовательность ХРР, с получением гидролизованного белкового продукта;
(б) отделение гидролизованного белкового продукта от фракции, богатой трипептидом;
(в) сушка фракции со стадии (б) с получением порошка, богатого трипептидом ХРР;
(г) применение порошка со стадии (в) в качестве ингредиента в приготовлении пищевого продукта.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03079075 | 2003-12-15 | ||
| EP03079075.2 | 2003-12-15 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU2006125434A true RU2006125434A (ru) | 2008-01-27 |
Family
ID=34684562
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2006125434/13A RU2006125434A (ru) | 2003-12-15 | 2004-11-19 | Пептиды, обладающие асе-ингибирующим действием |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20070141120A1 (ru) |
| EP (1) | EP1694140B1 (ru) |
| JP (1) | JP2007513900A (ru) |
| CN (1) | CN1893838A (ru) |
| AT (1) | ATE438311T1 (ru) |
| AU (1) | AU2004298742B2 (ru) |
| BR (1) | BRPI0416712A (ru) |
| CA (1) | CA2547737A1 (ru) |
| DE (1) | DE602004022453D1 (ru) |
| RU (1) | RU2006125434A (ru) |
| WO (1) | WO2005058070A1 (ru) |
| ZA (1) | ZA200604248B (ru) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2006239559B2 (en) * | 2005-04-28 | 2010-09-02 | Dsm Ip Assets B.V. | Peptides having an ace inhibiting effect |
| WO2006114193A1 (en) * | 2005-04-28 | 2006-11-02 | Unilever N.V. | Peptides having an ace inhibiting effect |
| CN111087446B (zh) * | 2019-12-30 | 2021-07-20 | 中新国际联合研究院 | 一种抑制血管紧张素转换酶的十肽及其应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4585757A (en) * | 1984-07-27 | 1986-04-29 | Texas Tech University Health Sciences Center | Hypotensive active peptides |
| JPH0655758B2 (ja) * | 1984-08-24 | 1994-07-27 | 味の素株式会社 | アミノ酸誘導体 |
| BE1003298A3 (nl) * | 1990-01-12 | 1992-02-18 | Tessenderlo Chem Nv | Werkwijze voor het bereiden van een enzymatisch hydrolysaat. |
| JP2873327B2 (ja) * | 1998-01-23 | 1999-03-24 | 工業技術院長 | アンジオテンシン変換酵素阻害剤 |
| JP4633876B2 (ja) * | 1999-11-11 | 2011-02-16 | カルピス株式会社 | トリペプチドの製造方法 |
| WO2001068114A1 (en) * | 2000-03-10 | 2001-09-20 | Monsanto Company | Novel peptides with anti-hypertensive activity |
| EP1287159A4 (en) * | 2000-05-08 | 2005-02-09 | Davisco Foods Int Inc | ENZYMATIC TREATMENT OF MOLECEPROTEINS FOR THE PRODUCTION OF BLOOD PRESSURE PENDING PEPTIDES, RESULTING PRODUCTS FROM THEREOF AND TREATMENT OF BLOOD PRESSURE IN MAMMALS |
| JP2003267994A (ja) * | 2002-03-11 | 2003-09-25 | Suetsuna Yoko | 新規なペプチドおよびアンジオテンシン変換酵素阻害剤 |
-
2004
- 2004-11-19 RU RU2006125434/13A patent/RU2006125434A/ru not_active Application Discontinuation
- 2004-11-19 CN CNA2004800370893A patent/CN1893838A/zh active Pending
- 2004-11-19 EP EP04820397A patent/EP1694140B1/en not_active Not-in-force
- 2004-11-19 CA CA002547737A patent/CA2547737A1/en not_active Abandoned
- 2004-11-19 AU AU2004298742A patent/AU2004298742B2/en not_active Ceased
- 2004-11-19 AT AT04820397T patent/ATE438311T1/de not_active IP Right Cessation
- 2004-11-19 ZA ZA200604248A patent/ZA200604248B/en unknown
- 2004-11-19 JP JP2006543411A patent/JP2007513900A/ja active Pending
- 2004-11-19 DE DE602004022453T patent/DE602004022453D1/de active Active
- 2004-11-19 BR BRPI0416712-0A patent/BRPI0416712A/pt not_active Application Discontinuation
- 2004-11-19 WO PCT/EP2004/013223 patent/WO2005058070A1/en active Application Filing
- 2004-11-19 US US10/582,759 patent/US20070141120A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU2004298742B2 (en) | 2008-07-31 |
| WO2005058070A1 (en) | 2005-06-30 |
| EP1694140A1 (en) | 2006-08-30 |
| BRPI0416712A (pt) | 2007-01-16 |
| CA2547737A1 (en) | 2005-06-30 |
| AU2004298742A1 (en) | 2005-06-30 |
| JP2007513900A (ja) | 2007-05-31 |
| EP1694140B1 (en) | 2009-08-05 |
| DE602004022453D1 (de) | 2009-09-17 |
| US20070141120A1 (en) | 2007-06-21 |
| CN1893838A (zh) | 2007-01-10 |
| ATE438311T1 (de) | 2009-08-15 |
| ZA200604248B (en) | 2007-11-28 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FA93 | Acknowledgement of application withdrawn (no request for examination) |
Effective date: 20080226 |