RS63359B1 - Heterociklična jedinjenja kao inhibitori pi3k-gama - Google Patents
Heterociklična jedinjenja kao inhibitori pi3k-gamaInfo
- Publication number
- RS63359B1 RS63359B1 RS20220521A RSP20220521A RS63359B1 RS 63359 B1 RS63359 B1 RS 63359B1 RS 20220521 A RS20220521 A RS 20220521A RS P20220521 A RSP20220521 A RS P20220521A RS 63359 B1 RS63359 B1 RS 63359B1
- Authority
- RS
- Serbia
- Prior art keywords
- pi3k
- heterocyclic compounds
- gamma inhibitors
- gamma
- inhibitors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562252050P | 2015-11-06 | 2015-11-06 | |
PCT/US2016/060468 WO2017079519A1 (en) | 2015-11-06 | 2016-11-04 | Heterocyclic compounds as pi3k-gamma inhibitors |
EP16805238.9A EP3371190B1 (en) | 2015-11-06 | 2016-11-04 | Heterocyclic compounds as pi3k-gamma inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
RS63359B1 true RS63359B1 (sr) | 2022-07-29 |
Family
ID=57460598
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RS20220521A RS63359B1 (sr) | 2015-11-06 | 2016-11-04 | Heterociklična jedinjenja kao inhibitori pi3k-gama |
Country Status (17)
Country | Link |
---|---|
US (4) | US10065963B2 (sr) |
EP (2) | EP3371190B1 (sr) |
JP (1) | JP6854817B2 (sr) |
AR (1) | AR106595A1 (sr) |
DK (1) | DK3371190T3 (sr) |
ES (1) | ES2915550T3 (sr) |
HR (1) | HRP20220599T1 (sr) |
HU (1) | HUE059324T2 (sr) |
LT (1) | LT3371190T (sr) |
MA (1) | MA43169B1 (sr) |
MD (1) | MD3371190T2 (sr) |
PL (1) | PL3371190T3 (sr) |
PT (1) | PT3371190T (sr) |
RS (1) | RS63359B1 (sr) |
SI (1) | SI3371190T1 (sr) |
TW (2) | TWI744256B (sr) |
WO (1) | WO2017079519A1 (sr) |
Families Citing this family (21)
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US20180185368A1 (en) | 2014-11-06 | 2018-07-05 | Lysosomal Therapeutics Inc. | Substituted pyrrolo[1,2-a]pyrimidines and their use in the treatment of medical disorders |
US10570135B2 (en) | 2014-11-06 | 2020-02-25 | Lysosomal Therapeutics Inc. | Substituted pyrazolo[1,5-A]pyrimidines and their use in the treatment of medical disorders |
US20170333435A1 (en) | 2014-11-06 | 2017-11-23 | Lysosomal Therapeutics Inc. | Substituted imidazo[1,5-a]pyrimidines and their use in the treatment of medical disorders |
US9586949B2 (en) | 2015-02-09 | 2017-03-07 | Incyte Corporation | Aza-heteroaryl compounds as PI3K-gamma inhibitors |
ES2915550T3 (es) | 2015-11-06 | 2022-06-23 | Incyte Corp | Compuestos heterocíclicos como inhibidores de PI3K-gamma |
AR107293A1 (es) | 2016-01-05 | 2018-04-18 | Incyte Corp | COMPUESTOS DE PIRIDINA Y PIRIDIMINA COMO INHIBIDORES DE PI3K-g |
MX2018010192A (es) * | 2016-02-25 | 2019-01-31 | Asceneuron S A | Inhibidores de glucosidasa. |
MX2018012208A (es) | 2016-04-06 | 2019-03-28 | Lysosomal Therapeutics Inc | Compuestos a base de imidazo [1,5-a] pirimidinil carboxamida y su uso en el tratamiento de trastornos médicos. |
MX2018012207A (es) | 2016-04-06 | 2019-03-28 | Lysosomal Therapeutics Inc | Compuestos de pirrol[1,2-a]pirimidinil carboxamida y su uso en el tratamiento de trastornos médicos. |
KR20230104752A (ko) | 2016-04-06 | 2023-07-10 | 비알 - 알&디 인베스트먼츠, 에스.에이. | 피라졸로[1,5-a]피리미디닐 카르복스아미드 화합물및 의학적 장애의 치료에서의 그의 용도 |
EP3452455A4 (en) | 2016-05-05 | 2019-11-13 | Lysosomal Therapeutics Inc. | SUBSTITUTED IMDAZO [1,2-] PYRIDINES, SUBSTITUTED IMIDAZO [1,2-] PYRAZINES, RELATED COMPOUNDS AND THEIR USE IN THE TREATMENT OF ILLNESSES |
SG11201809693SA (en) | 2016-05-05 | 2018-11-29 | Lysosomal Therapeutics Inc | SUBSTITUTED IMIDAZO[1,2-b]PYRIDAZINES, SUBSTITUTED IMIDAZO[1,5-b]PYRIDAZINES, RELATED COMPOUNDS, AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS |
TW201803871A (zh) | 2016-06-24 | 2018-02-01 | 英塞特公司 | 作為PI3K-γ抑制劑之雜環化合物 |
LT3697789T (lt) | 2017-10-18 | 2021-12-10 | Incyte Corporation | Kondensuoti imidazolo dariniai, pakeisti tretinėmis hidroksigrupėmis, kaip pi3k-gama inhibitoriai |
TW201927777A (zh) * | 2017-12-19 | 2019-07-16 | 大陸商基石藥業(蘇州)有限公司 | Ido抑制劑 |
FI3847175T3 (fi) | 2018-09-05 | 2024-03-22 | Incyte Corp | Fosfoinositidi-3-kinaasin (pi3k) inhibiittorin kiteisiä muotoja |
SG11202110523XA (en) | 2019-03-26 | 2021-10-28 | Ventyx Biosciences Inc | Tyk2 pseudokinase ligands |
EP3953345B1 (en) * | 2019-04-11 | 2023-04-05 | Janssen Pharmaceutica NV | Pyridine rings containing derivatives as malt1 inhibitors |
US11464783B2 (en) | 2019-06-06 | 2022-10-11 | Aligos Therapeutics, Inc. | Heterocyclic compounds |
BR112022008821A2 (pt) * | 2019-11-08 | 2022-08-23 | Ventyx Biosciences Inc | Ligantes de pseudoquinase tyk2 |
CN116348453A (zh) * | 2021-04-25 | 2023-06-27 | 烨辉医药科技(上海)有限公司 | 杂芳族甲酰胺化合物及其用途 |
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2016
- 2016-11-04 ES ES16805238T patent/ES2915550T3/es active Active
- 2016-11-04 HR HRP20220599TT patent/HRP20220599T1/hr unknown
- 2016-11-04 EP EP16805238.9A patent/EP3371190B1/en active Active
- 2016-11-04 EP EP22162035.4A patent/EP4086259A1/en not_active Withdrawn
- 2016-11-04 HU HUE16805238A patent/HUE059324T2/hu unknown
- 2016-11-04 US US15/343,375 patent/US10065963B2/en active Active
- 2016-11-04 PT PT168052389T patent/PT3371190T/pt unknown
- 2016-11-04 LT LTEPPCT/US2016/060468T patent/LT3371190T/lt unknown
- 2016-11-04 PL PL16805238.9T patent/PL3371190T3/pl unknown
- 2016-11-04 JP JP2018523015A patent/JP6854817B2/ja active Active
- 2016-11-04 MD MDE20180887T patent/MD3371190T2/ro unknown
- 2016-11-04 TW TW105136055A patent/TWI744256B/zh active
- 2016-11-04 MA MA43169A patent/MA43169B1/fr unknown
- 2016-11-04 TW TW110136698A patent/TWI824309B/zh active
- 2016-11-04 WO PCT/US2016/060468 patent/WO2017079519A1/en active Application Filing
- 2016-11-04 SI SI201631549T patent/SI3371190T1/sl unknown
- 2016-11-04 AR ARP160103370A patent/AR106595A1/es unknown
- 2016-11-04 RS RS20220521A patent/RS63359B1/sr unknown
- 2016-11-04 DK DK16805238.9T patent/DK3371190T3/da active
-
2018
- 2018-07-25 US US16/045,358 patent/US10472368B2/en active Active
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2019
- 2019-10-01 US US16/589,523 patent/US11091491B2/en active Active
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2021
- 2021-06-24 US US17/356,984 patent/US11773102B2/en active Active
Also Published As
Publication number | Publication date |
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US10472368B2 (en) | 2019-11-12 |
DK3371190T3 (da) | 2022-05-23 |
LT3371190T (lt) | 2022-08-10 |
JP2018532760A (ja) | 2018-11-08 |
JP6854817B2 (ja) | 2021-04-07 |
EP4086259A1 (en) | 2022-11-09 |
TW202204362A (zh) | 2022-02-01 |
TW201726679A (zh) | 2017-08-01 |
MA43169A (fr) | 2018-09-12 |
US10065963B2 (en) | 2018-09-04 |
US20170129899A1 (en) | 2017-05-11 |
EP3371190A1 (en) | 2018-09-12 |
US11773102B2 (en) | 2023-10-03 |
MA43169B1 (fr) | 2022-05-31 |
PL3371190T3 (pl) | 2022-11-07 |
US20190062336A1 (en) | 2019-02-28 |
TWI744256B (zh) | 2021-11-01 |
TWI824309B (zh) | 2023-12-01 |
WO2017079519A1 (en) | 2017-05-11 |
AR106595A1 (es) | 2018-01-31 |
US20230009843A1 (en) | 2023-01-12 |
EP3371190B1 (en) | 2022-03-30 |
HRP20220599T1 (hr) | 2022-06-24 |
MD3371190T2 (ro) | 2022-09-30 |
HUE059324T2 (hu) | 2022-11-28 |
ES2915550T3 (es) | 2022-06-23 |
US11091491B2 (en) | 2021-08-17 |
PT3371190T (pt) | 2022-07-08 |
US20200031837A1 (en) | 2020-01-30 |
SI3371190T1 (sl) | 2022-08-31 |
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