PL366981A1 - Technologia ekspresji białek zawierających jednostkę będącą hybrydą izotypów przeciwciała - Google Patents

Technologia ekspresji białek zawierających jednostkę będącą hybrydą izotypów przeciwciała

Info

Publication number
PL366981A1
PL366981A1 PL02366981A PL36698102A PL366981A1 PL 366981 A1 PL366981 A1 PL 366981A1 PL 02366981 A PL02366981 A PL 02366981A PL 36698102 A PL36698102 A PL 36698102A PL 366981 A1 PL366981 A1 PL 366981A1
Authority
PL
Poland
Prior art keywords
proteins containing
antibody moiety
expression technology
isotype antibody
hybrid isotype
Prior art date
Application number
PL02366981A
Other languages
English (en)
Other versions
PL206701B1 (pl
Inventor
Stephen D. Gillies
Jeffrey Way
Kin-Ming Lo
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of PL366981A1 publication Critical patent/PL366981A1/pl
Publication of PL206701B1 publication Critical patent/PL206701B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/53—Hinge
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL366981A 2001-03-07 2002-03-07 Immunoglobulinowe białko fuzyjne, kodujący je kwas nukleinowy, replikujący wektor ekspresji zawierający taki kwas nukleinowy, eukariotyczna komórka gospodarza zawierająca taki wektor ekspresji oraz sposób zwiększania ekspresji takiego białka fuzyjnego PL206701B1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27409601P 2001-03-07 2001-03-07

Publications (2)

Publication Number Publication Date
PL366981A1 true PL366981A1 (pl) 2005-02-07
PL206701B1 PL206701B1 (pl) 2010-09-30

Family

ID=23046749

Family Applications (1)

Application Number Title Priority Date Filing Date
PL366981A PL206701B1 (pl) 2001-03-07 2002-03-07 Immunoglobulinowe białko fuzyjne, kodujący je kwas nukleinowy, replikujący wektor ekspresji zawierający taki kwas nukleinowy, eukariotyczna komórka gospodarza zawierająca taki wektor ekspresji oraz sposób zwiększania ekspresji takiego białka fuzyjnego

Country Status (17)

Country Link
US (2) US7148321B2 (pl)
EP (1) EP1366067B1 (pl)
JP (1) JP4234438B2 (pl)
KR (2) KR20090010127A (pl)
CN (1) CN1330664C (pl)
AU (1) AU2002248571B2 (pl)
BR (1) BR0207854A (pl)
CA (1) CA2440221C (pl)
DK (1) DK1366067T3 (pl)
ES (1) ES2393733T3 (pl)
HU (1) HUP0303428A2 (pl)
MX (1) MXPA03008031A (pl)
PL (1) PL206701B1 (pl)
PT (1) PT1366067E (pl)
RU (1) RU2003129528A (pl)
WO (1) WO2002072605A2 (pl)
ZA (1) ZA200307792B (pl)

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ZA200307792B (en) 2004-07-06
AU2002248571B2 (en) 2007-01-18
CA2440221A1 (en) 2002-09-19
EP1366067A4 (en) 2005-07-20
PL206701B1 (pl) 2010-09-30
PT1366067E (pt) 2012-11-29
KR20090010127A (ko) 2009-01-28
US20060263856A1 (en) 2006-11-23
US8066994B2 (en) 2011-11-29
RU2003129528A (ru) 2005-04-10
KR20030092015A (ko) 2003-12-03
CA2440221C (en) 2013-02-05
WO2002072605A3 (en) 2002-11-14
CN1509293A (zh) 2004-06-30
JP4234438B2 (ja) 2009-03-04
EP1366067B1 (en) 2012-09-26
DK1366067T3 (da) 2012-10-22
WO2002072605A2 (en) 2002-09-19
KR100900176B1 (ko) 2009-06-02
JP2004525630A (ja) 2004-08-26
US7148321B2 (en) 2006-12-12
CN1330664C (zh) 2007-08-08
US20030044423A1 (en) 2003-03-06
BR0207854A (pt) 2004-08-24
ES2393733T3 (es) 2012-12-27
MXPA03008031A (es) 2003-12-04
EP1366067A2 (en) 2003-12-03

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