US4844119A
(en)
*
|
1988-11-21 |
1989-07-04 |
Allied-Signal Inc. |
Integrated three-way and isolation solenoid valve
|
ATE311895T1
(de)
*
|
1992-05-26 |
2005-12-15 |
Immunex Corp |
Neue zytokine die cd30 binden
|
US6429290B1
(en)
|
1994-08-17 |
2002-08-06 |
The Rockefeller University |
OB polypeptides, modified forms and derivatives
|
US6309853B1
(en)
|
1994-08-17 |
2001-10-30 |
The Rockfeller University |
Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof
|
US6350730B1
(en)
|
1994-08-17 |
2002-02-26 |
The Rockefeller University |
OB polypeptides and modified forms as modulators of body weight
|
US6124448A
(en)
*
|
1994-08-17 |
2000-09-26 |
The Rockfeller University |
Nucleic acid primers and probes for the mammalian OB gene
|
US6471956B1
(en)
|
1994-08-17 |
2002-10-29 |
The Rockefeller University |
Ob polypeptides, modified forms and compositions thereto
|
US6048837A
(en)
*
|
1994-08-17 |
2000-04-11 |
The Rockefeller University |
OB polypeptides as modulators of body weight
|
US6001968A
(en)
|
1994-08-17 |
1999-12-14 |
The Rockefeller University |
OB polypeptides, modified forms and compositions
|
US6936439B2
(en)
*
|
1995-11-22 |
2005-08-30 |
Amgen Inc. |
OB fusion protein compositions and methods
|
US20030040467A1
(en)
*
|
1998-06-15 |
2003-02-27 |
Mary Ann Pelleymounter |
Ig/ob fusions and uses thereof.
|
US7070771B1
(en)
|
1996-12-09 |
2006-07-04 |
Regents Of The University Of California |
Methods of expressing chimeric mouse and human CD40 ligand in human CD40+ cells
|
CA2693296C
(en)
*
|
1997-12-08 |
2013-09-10 |
Merck Patent Gmbh |
Heterodimeric fusion proteins useful for targeted immune therapy and general immune stimulation
|
WO1999040187A1
(de)
*
|
1998-02-06 |
1999-08-12 |
Hinrich Abken |
Nukleinsäuren zur modulation zellulärer aktivierung
|
US20030105294A1
(en)
*
|
1998-02-25 |
2003-06-05 |
Stephen Gillies |
Enhancing the circulating half life of antibody-based fusion proteins
|
US7001999B1
(en)
*
|
1998-04-15 |
2006-02-21 |
Ludwig Institute For Cancer Research |
Tumor associated nucleic acids and uses therefor
|
AU3560399A
(en)
*
|
1998-04-15 |
1999-11-01 |
Ludwig Institute For Cancer Research |
Tumor associated nucleic acids and uses therefor
|
ATE329622T1
(de)
*
|
1998-04-15 |
2006-07-15 |
Lexigen Pharm Corp |
Steigerung der antikörper-zytokin- fusionsproteinmediierten immunantwort durch mitverabreichung mit einem angiogeneseinhibitor
|
US6245525B1
(en)
|
1998-07-27 |
2001-06-12 |
Ludwig Institute For Cancer Research |
Tumor associated nucleic acids and uses therefor
|
EP1124961B9
(en)
|
1998-10-23 |
2010-07-21 |
Kirin-Amgen Inc. |
Thrombopoietic compounds
|
US7304150B1
(en)
*
|
1998-10-23 |
2007-12-04 |
Amgen Inc. |
Methods and compositions for the prevention and treatment of anemia
|
US6660843B1
(en)
|
1998-10-23 |
2003-12-09 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
US7488590B2
(en)
|
1998-10-23 |
2009-02-10 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
CZ20014123A3
(cs)
*
|
1999-05-19 |
2002-06-12 |
Lexigen Pharmaceuticals Corp. |
Exprese a export interferonů-alfa jako Fc fúzních proteinů
|
SK782002A3
(en)
|
1999-07-21 |
2003-08-05 |
Lexigen Pharm Corp |
FC fusion proteins for enhancing the immunogenicity of protein and peptide antigens
|
CA2349406C
(en)
*
|
1999-09-03 |
2011-01-11 |
Amgen Inc. |
Compositions and methods for the prevention or treatment of cancer and bone loss associated with cancer
|
US20050202538A1
(en)
*
|
1999-11-12 |
2005-09-15 |
Merck Patent Gmbh |
Fc-erythropoietin fusion protein with improved pharmacokinetics
|
JP2003514552A
(ja)
|
1999-11-12 |
2003-04-22 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング |
改善された性質を有するエリトロポエチンの形態
|
US6808902B1
(en)
|
1999-11-12 |
2004-10-26 |
Amgen Inc. |
Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
|
JP2003520579A
(ja)
*
|
1999-12-08 |
2003-07-08 |
アムジェン インコーポレイテッド |
インターフェロン様分子およびその使用
|
JP5179689B2
(ja)
|
2000-02-11 |
2013-04-10 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング |
抗体ベース融合タンパク質の循環系内半減期の増強
|
AU2001255740B2
(en)
*
|
2000-04-25 |
2006-03-16 |
Immunex Corporation |
Method for treatment of tumors using photodynamic therapy
|
AU2001259432B2
(en)
*
|
2000-05-03 |
2005-04-21 |
Amgen Inc. |
Modified peptides, comprising an FC domain, as therapeutic agents
|
DK1294401T3
(da)
*
|
2000-06-29 |
2007-10-08 |
Merck Patent Gmbh |
Forbedring af antistof/cytokin-fusionsproteinmedierede immunresponser ved kombineret behandling med immuncytokin-optagelsesforberende midler
|
US6652854B2
(en)
|
2000-08-08 |
2003-11-25 |
Immunex Corporation |
Methods for treating autoimmune and chronic inflammatory conditions using antagonists of CD30 or CD30L
|
US9539348B2
(en)
*
|
2000-08-18 |
2017-01-10 |
East Carolina University |
Monoclonal antibody DS6, tumor-associated antigen CA6, and methods of use thereof
|
JP4744062B2
(ja)
*
|
2000-10-18 |
2011-08-10 |
アメリカ合衆国 |
生殖能力に不可欠なヒト遺伝子
|
US20040018194A1
(en)
*
|
2000-11-28 |
2004-01-29 |
Francisco Joseph A. |
Recombinant anti-CD30 antibodies and uses thereof
|
US7090843B1
(en)
|
2000-11-28 |
2006-08-15 |
Seattle Genetics, Inc. |
Recombinant anti-CD30 antibodies and uses thereof
|
US7348406B2
(en)
*
|
2001-01-16 |
2008-03-25 |
Serono Genetics Institute S.A. |
Metabolic gene polynucleotides and polypeptides and uses thereof
|
CA2440221C
(en)
*
|
2001-03-07 |
2013-02-05 |
Merck Patent Gesellschaft Mit Beschraenkter Haftung |
Expression technology for proteins containing a hybrid isotype antibody moiety
|
WO2002079415A2
(en)
*
|
2001-03-30 |
2002-10-10 |
Lexigen Pharmaceuticals Corp. |
Reducing the immunogenicity of fusion proteins
|
PL205352B1
(pl)
*
|
2001-05-03 |
2010-04-30 |
Merck Patent Gmbh |
Rekombinowane przeciwciało specyficzne dla nowotworu
|
CN1518459A
(zh)
*
|
2001-06-22 |
2004-08-04 |
��һ��������ҩ��ʽ���� |
嗜酸性粒细胞疾病的治疗剂
|
WO2003009863A1
(en)
*
|
2001-07-26 |
2003-02-06 |
Genset S.A. |
Agonists and antagonists of cofoxin for use in the treatment of metabolic disorders
|
US7270960B2
(en)
*
|
2001-08-29 |
2007-09-18 |
Pacific Northwest Research Institute |
Diagnosis of ovarian carcinomas
|
US7332474B2
(en)
|
2001-10-11 |
2008-02-19 |
Amgen Inc. |
Peptides and related compounds having thrombopoietic activity
|
US7521053B2
(en)
|
2001-10-11 |
2009-04-21 |
Amgen Inc. |
Angiopoietin-2 specific binding agents
|
US7138370B2
(en)
|
2001-10-11 |
2006-11-21 |
Amgen Inc. |
Specific binding agents of human angiopoietin-2
|
EP1454138B1
(en)
*
|
2001-12-04 |
2012-01-18 |
Merck Patent GmbH |
Immunocytokines with modulated selectivity
|
US7786282B2
(en)
|
2001-12-06 |
2010-08-31 |
The Regents Of The University Of California |
Nucleic acid molecules encoding TNF-α ligand polypeptides having a CD154 domain
|
WO2003059282A2
(en)
*
|
2002-01-09 |
2003-07-24 |
Medarex, Inc. |
Human monoclonal antibodies against cd30
|
US20040136992A1
(en)
|
2002-08-28 |
2004-07-15 |
Burton Paul B. J. |
Compositions and method for treating cardiovascular disease
|
RU2366664C2
(ru)
*
|
2002-12-17 |
2009-09-10 |
Мерк Патент Гмбх |
Гуманизированное антитело (н14.18) на основании антитела 14.18 мыши, связывающееся с gd2, и его слияние с il-2
|
WO2004100882A2
(en)
*
|
2003-05-06 |
2004-11-25 |
Syntonix Pharmaceuticals, Inc. |
Inhibition of drug binding to serum albumin
|
US7348004B2
(en)
|
2003-05-06 |
2008-03-25 |
Syntonix Pharmaceuticals, Inc. |
Immunoglobulin chimeric monomer-dimer hybrids
|
PT1624891E
(pt)
*
|
2003-05-06 |
2010-01-05 |
Syntonix Pharmaceuticals Inc |
Proteínas quiméricas de factor de coagulação-fc destinadas ao tratamento da hemofilia
|
TWI353991B
(en)
|
2003-05-06 |
2011-12-11 |
Syntonix Pharmaceuticals Inc |
Immunoglobulin chimeric monomer-dimer hybrids
|
US20050009110A1
(en)
*
|
2003-07-08 |
2005-01-13 |
Xiao-Jia Chang |
Methods of producing antibodies for diagnostics and therapeutics
|
US20050069521A1
(en)
*
|
2003-08-28 |
2005-03-31 |
Emd Lexigen Research Center Corp. |
Enhancing the circulating half-life of interleukin-2 proteins
|
EP1699822B1
(en)
|
2003-12-30 |
2008-04-23 |
MERCK PATENT GmbH |
Il-7 fusion proteins with antibody portions, their preparation and their use
|
KR20060124656A
(ko)
*
|
2003-12-31 |
2006-12-05 |
메르크 파텐트 게엠베하 |
개선된 약물동태를 가지는 Fc-에리스로포이에틴 융합단백질
|
WO2005066348A2
(en)
*
|
2004-01-05 |
2005-07-21 |
Emd Lexigen Research Center Corp. |
Interleukin-12 targeted to oncofoetal fibronectin
|
AU2005207960A1
(en)
*
|
2004-01-28 |
2005-08-11 |
Syntonix Pharmaceuticals, Inc. |
Heterodimeric follicle stimulating hormone-Fc (FSH-Fc) fusion proteins for the treatment of infertility
|
AU2004317159B2
(en)
|
2004-02-12 |
2010-12-23 |
The United States Of America, As Represented By Secretary, Department Of Health And Human Services |
Therapeutic administration of the scrambled anti-angiogenic peptide C16Y
|
EP1771205B1
(en)
|
2004-06-18 |
2016-10-26 |
Ambrx, Inc. |
Novel antigen-binding polypeptides and their uses
|
US7670595B2
(en)
*
|
2004-06-28 |
2010-03-02 |
Merck Patent Gmbh |
Fc-interferon-beta fusion proteins
|
US8143380B2
(en)
*
|
2004-07-08 |
2012-03-27 |
Amgen Inc. |
Therapeutic peptides
|
DK1773884T3
(da)
|
2004-08-03 |
2012-05-21 |
Innate Pharma |
Terapeutiske og diagnostiske fremgangsmåder og sammensætninger til targeting af 4ig-b7-h3 og dets tilsvarende nk-celle-receptor
|
DK1797127T3
(da)
|
2004-09-24 |
2017-10-02 |
Amgen Inc |
Modificerede Fc-molekyler
|
EP1802345A2
(en)
*
|
2004-10-01 |
2007-07-04 |
Medarex, Inc. |
Methods of treating cd30 positive lymphomas
|
KR20070085886A
(ko)
*
|
2004-12-09 |
2007-08-27 |
메르크 파텐트 게엠베하 |
감소된 면역원성의 il-7 변이체
|
MX2007009940A
(es)
|
2005-02-18 |
2007-10-10 |
Medarex Inc |
Anticuerpos monoclonales que carecen de residuos fucosilo contra cd30.
|
WO2006116246A2
(en)
*
|
2005-04-25 |
2006-11-02 |
Medarex, Inc. |
Method of treating cd30 positive lymphomas
|
JP2008544246A
(ja)
*
|
2005-06-17 |
2008-12-04 |
コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ |
正確な磁気バイオセンサー
|
US8008453B2
(en)
|
2005-08-12 |
2011-08-30 |
Amgen Inc. |
Modified Fc molecules
|
US20070104689A1
(en)
*
|
2005-09-27 |
2007-05-10 |
Merck Patent Gmbh |
Compositions and methods for treating tumors presenting survivin antigens
|
TW200722436A
(en)
*
|
2005-10-21 |
2007-06-16 |
Hoffmann La Roche |
A peptide-immunoglobulin-conjugate
|
EP1976883B1
(en)
*
|
2006-01-17 |
2012-10-03 |
Medarex, Inc. |
Monoclonal antibodies against cd30 lacking in fucosyl and xylosyl residues
|
EP1986677A2
(en)
*
|
2006-01-25 |
2008-11-05 |
Amgen Inc. |
Thrombopoietic compounds
|
JO3324B1
(ar)
|
2006-04-21 |
2019-03-13 |
Amgen Inc |
مركبات علاجية مجففة بالتبريد تتعلق بالعصارة الهضمية
|
US7981425B2
(en)
|
2006-06-19 |
2011-07-19 |
Amgen Inc. |
Thrombopoietic compounds
|
JO2913B1
(en)
|
2008-02-20 |
2015-09-15 |
امجين إنك, |
Antibodies directed towards angiopoietin-1 and angiopoietin-2 proteins and their uses
|
EA201171259A1
(ru)
*
|
2009-04-22 |
2012-05-30 |
Мерк Патент Гмбх |
Антительные гибридные белки с модифицированными сайтами связывания fcrn
|
US8871191B2
(en)
|
2009-08-14 |
2014-10-28 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Use of IL-15 preparations to treat lymphopenia
|
MY192639A
(en)
|
2010-07-09 |
2022-08-29 |
Bioverativ Therapeutics Inc |
Factor ix polypeptides and methods of use thereof
|
EP3508573A1
(en)
|
2010-07-09 |
2019-07-10 |
Bioverativ Therapeutics Inc. |
Systems for factor viii processing and methods thereof
|
AU2012286048A1
(en)
|
2011-07-18 |
2014-02-20 |
Arts Biologics A/S |
Long acting luteinizing hormone (LH) compound
|
US9605083B2
(en)
|
2011-08-16 |
2017-03-28 |
Emory University |
JAML specific binding agents, antibodies, and uses related thereto
|
EP3896759A1
(en)
|
2011-10-05 |
2021-10-20 |
OneD Material, Inc. |
Silicon nanostructure active materials for lithium ion batteries and processes, compositions, components, and devices related thereto
|
US9360414B2
(en)
*
|
2011-10-14 |
2016-06-07 |
University of Pittsburgh—of the Commonwealth System of Higher Education |
Light refraction imaging to measure liquid volume
|
EA029602B1
(ru)
|
2011-11-29 |
2018-04-30 |
Проклара Байосайенсиз, Инк. |
Применение белков р3 бактериофага в качестве агентов, связывающих амилоид
|
CA2864092C
(en)
*
|
2012-02-10 |
2021-06-29 |
Seattle Genetics, Inc. |
Detection and treatment of cd30+ cancers
|
EP3431492B1
(en)
*
|
2012-04-27 |
2020-12-23 |
Novo Nordisk A/S |
Human cd30 ligand antigen binding proteins
|
EP2846822A2
(en)
|
2012-05-11 |
2015-03-18 |
Prorec Bio AB |
Method for diagnosis and treatment of prolactin associated disorders
|
GB201216649D0
(en)
*
|
2012-09-18 |
2012-10-31 |
Univ Birmingham |
Agents and methods
|
EA033666B1
(ru)
|
2012-10-02 |
2019-11-14 |
Proclara Biosciences Inc |
Амилоидсвязывающие белки и их применение
|
CN103509121B
(zh)
|
2012-11-22 |
2015-01-28 |
苏州康宁杰瑞生物科技有限公司 |
一种fsh融合蛋白及其制备方法和用途
|
WO2014093698A1
(en)
|
2012-12-12 |
2014-06-19 |
The Methodist Hospital Research Institute |
Multi-aptamer-based, cell-specific, one-step tumor cell detection assays
|
AU2014228938B2
(en)
|
2013-03-15 |
2019-05-02 |
Bioverativ Therapeutics Inc. |
Factor IX polypeptide formulations
|
AU2014274253B2
(en)
|
2013-05-28 |
2018-06-14 |
Proclara Biosciences, Inc. |
Polypeptides comprising a modified bacteriophage g3p amino acid sequence with reduced immunogenicity
|
KR20170085132A
(ko)
|
2014-12-03 |
2017-07-21 |
프로클라라 바이오사이언시즈, 인크. |
글리코실화 신호가 결핍된 변형된 박테리오파지 g3p 아미노산 서열을 포함하는 폴리펩티드
|
WO2016196344A1
(en)
|
2015-05-30 |
2016-12-08 |
Molecular Templates, Inc. |
De-immunized, shiga toxin a subunit scaffolds and cell-targeting molecules comprising the same
|
EP3370771A4
(en)
|
2015-11-03 |
2019-06-19 |
Ambrx, Inc. |
ANTI-CD3-FOLATE CONJUGATES AND USES THEREOF
|
SG10201601719RA
(en)
|
2016-03-04 |
2017-10-30 |
Agency Science Tech & Res |
Anti-LAG-3 Antibodies
|
SG10201603721TA
(en)
|
2016-05-10 |
2017-12-28 |
Agency Science Tech & Res |
Anti-CTLA-4 Antibodies
|
IT201700084299A1
(it)
|
2017-07-24 |
2019-01-24 |
Univ Degli Studi Padova |
Peptidi derivati dal GAP24 per l’uso nel trattamento della forma X della neuropatia periferica di Charcot-Marie-Tooth
|
WO2020002565A1
(en)
*
|
2018-06-27 |
2020-01-02 |
Sabine Bauer |
Implants for recruiting and removing circulating tumor cells
|
AR124895A1
(es)
*
|
2021-02-17 |
2023-05-17 |
Prometheus Biosciences Inc |
Anticuerpos anti-cd30l y usos de estos
|
WO2023173084A1
(en)
|
2022-03-11 |
2023-09-14 |
University Of Rochester |
Cyclopeptibodies and uses thereof
|