PL3456717T3 - Pochodna 4,6-diaminochinolino-3-karbonitrylu jako modulator cot (cancer osaka thyroid) do leczenia choroby zapalnej - Google Patents
Pochodna 4,6-diaminochinolino-3-karbonitrylu jako modulator cot (cancer osaka thyroid) do leczenia choroby zapalnejInfo
- Publication number
- PL3456717T3 PL3456717T3 PL18186568T PL18186568T PL3456717T3 PL 3456717 T3 PL3456717 T3 PL 3456717T3 PL 18186568 T PL18186568 T PL 18186568T PL 18186568 T PL18186568 T PL 18186568T PL 3456717 T3 PL3456717 T3 PL 3456717T3
- Authority
- PL
- Poland
- Prior art keywords
- cot
- diamino
- quinoline
- modulator
- inflammatory disease
- Prior art date
Links
- WATPKLRWBYNCDK-UHFFFAOYSA-N 4,6-diaminoquinoline-3-carbonitrile Chemical class N1=CC(C#N)=C(N)C2=CC(N)=CC=C21 WATPKLRWBYNCDK-UHFFFAOYSA-N 0.000 title 1
- 206010028980 Neoplasm Diseases 0.000 title 1
- 201000011510 cancer Diseases 0.000 title 1
- 208000027866 inflammatory disease Diseases 0.000 title 1
- 210000001685 thyroid gland Anatomy 0.000 title 1
Classifications
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- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
- C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
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- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
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- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
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- Communicable Diseases (AREA)
- Urology & Nephrology (AREA)
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Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562189158P | 2015-07-06 | 2015-07-06 | |
US201562269060P | 2015-12-17 | 2015-12-17 | |
PCT/US2016/040520 WO2017007689A1 (en) | 2015-07-06 | 2016-06-30 | Cot modulators and methods of use thereof |
EP18186568.4A EP3456717B1 (en) | 2015-07-06 | 2016-06-30 | 4,6-diamino-quinoline-3-carbonitrile derivative as cancer osaka thyroid (cot) modulator for treating inflammatory disease |
EP16738976.6A EP3191470B1 (en) | 2015-07-06 | 2016-06-30 | Cot modulators and methods of use thereof |
Publications (1)
Publication Number | Publication Date |
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PL3456717T3 true PL3456717T3 (pl) | 2021-10-25 |
Family
ID=56411943
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL16738976T PL3191470T3 (pl) | 2015-07-06 | 2016-06-30 | Modulatory Cot i sposoby ich zastosowania |
PL18186568T PL3456717T3 (pl) | 2015-07-06 | 2016-06-30 | Pochodna 4,6-diaminochinolino-3-karbonitrylu jako modulator cot (cancer osaka thyroid) do leczenia choroby zapalnej |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PL16738976T PL3191470T3 (pl) | 2015-07-06 | 2016-06-30 | Modulatory Cot i sposoby ich zastosowania |
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US (7) | US20170008905A1 (pl) |
EP (3) | EP3456717B1 (pl) |
JP (6) | JP6430060B2 (pl) |
KR (5) | KR102073641B1 (pl) |
CN (3) | CN109879859B (pl) |
AU (5) | AU2016290820B2 (pl) |
BR (1) | BR102016015656B1 (pl) |
CA (1) | CA2971640C (pl) |
CL (1) | CL2017003356A1 (pl) |
CO (1) | CO2017013351A2 (pl) |
CR (1) | CR20170599A (pl) |
CU (1) | CU20170172A7 (pl) |
CY (1) | CY1121750T1 (pl) |
DK (1) | DK3191470T3 (pl) |
DO (1) | DOP2017000311A (pl) |
EA (1) | EA036788B1 (pl) |
EC (1) | ECSP17084635A (pl) |
ES (2) | ES2872076T3 (pl) |
HR (1) | HRP20190853T1 (pl) |
HU (1) | HUE043310T2 (pl) |
IL (4) | IL293770B2 (pl) |
LT (1) | LT3191470T (pl) |
MA (1) | MA39422B1 (pl) |
ME (1) | ME03425B (pl) |
MX (1) | MX370984B (pl) |
MY (1) | MY196173A (pl) |
NZ (2) | NZ750707A (pl) |
PE (1) | PE20180462A1 (pl) |
PH (2) | PH12018500031A1 (pl) |
PL (2) | PL3191470T3 (pl) |
PT (2) | PT3191470T (pl) |
RS (1) | RS58639B1 (pl) |
SA (1) | SA517381350B1 (pl) |
SG (1) | SG11201702041PA (pl) |
SI (2) | SI3456717T1 (pl) |
SV (1) | SV2017005605A (pl) |
TW (3) | TWI699361B (pl) |
UA (1) | UA123010C2 (pl) |
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