PL3190113T3 - Związki pirolopirymidynowe stosowane jako agonista TLR7 - Google Patents

Związki pirolopirymidynowe stosowane jako agonista TLR7

Info

Publication number
PL3190113T3
PL3190113T3 PL15831451T PL15831451T PL3190113T3 PL 3190113 T3 PL3190113 T3 PL 3190113T3 PL 15831451 T PL15831451 T PL 15831451T PL 15831451 T PL15831451 T PL 15831451T PL 3190113 T3 PL3190113 T3 PL 3190113T3
Authority
PL
Poland
Prior art keywords
compounds used
tlr7 agonist
pyrrolopyrimidine compounds
pyrrolopyrimidine
tlr7
Prior art date
Application number
PL15831451T
Other languages
English (en)
Inventor
Zhaozhong DING
Hao Wu
Fei Sun
Lifang Wu
Ling Yang
Original Assignee
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN201410405136.0A external-priority patent/CN105367576A/zh
Application filed by Chia Tai Tianqing Pharmaceutical Group Co., Ltd. filed Critical Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Publication of PL3190113T3 publication Critical patent/PL3190113T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
PL15831451T 2014-08-15 2015-08-14 Związki pirolopirymidynowe stosowane jako agonista TLR7 PL3190113T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CN201410405136.0A CN105367576A (zh) 2014-08-15 2014-08-15 作为tlr7激动剂的吡咯并嘧啶化合物
CN201510392499 2015-07-06
EP15831451.8A EP3190113B1 (en) 2014-08-15 2015-08-14 Pyrrolopyrimidine compounds used as tlr7 agonist
PCT/CN2015/086909 WO2016023511A1 (zh) 2014-08-15 2015-08-14 作为tlr7激动剂的吡咯并嘧啶化合物

Publications (1)

Publication Number Publication Date
PL3190113T3 true PL3190113T3 (pl) 2021-10-25

Family

ID=55303885

Family Applications (1)

Application Number Title Priority Date Filing Date
PL15831451T PL3190113T3 (pl) 2014-08-15 2015-08-14 Związki pirolopirymidynowe stosowane jako agonista TLR7

Country Status (26)

Country Link
US (2) US9962388B2 (pl)
EP (1) EP3190113B1 (pl)
JP (2) JP6328341B2 (pl)
KR (2) KR102215609B1 (pl)
CN (4) CN110938076B (pl)
AU (3) AU2015303558B2 (pl)
BR (1) BR112017002811B1 (pl)
CA (1) CA2958097C (pl)
CL (1) CL2017000379A1 (pl)
DK (1) DK3190113T3 (pl)
EA (1) EA032824B1 (pl)
ES (1) ES2875313T3 (pl)
HR (1) HRP20210927T1 (pl)
HU (1) HUE054672T2 (pl)
IL (2) IL250586B (pl)
LT (1) LT3190113T (pl)
MX (1) MX2017002028A (pl)
MY (1) MY190026A (pl)
PH (2) PH12017500281A1 (pl)
PL (1) PL3190113T3 (pl)
PT (1) PT3190113T (pl)
SG (2) SG10201809918RA (pl)
SI (1) SI3190113T1 (pl)
UA (1) UA117634C2 (pl)
WO (1) WO2016023511A1 (pl)
ZA (1) ZA201803736B (pl)

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