PL2928878T3 - Pochodne 5-fluoro-N -(pirydyn-2-ylo)pirydyno-2-aminy zawierające grupę sulfoksyiminową - Google Patents

Pochodne 5-fluoro-N -(pirydyn-2-ylo)pirydyno-2-aminy zawierające grupę sulfoksyiminową

Info

Publication number
PL2928878T3
PL2928878T3 PL13792885T PL13792885T PL2928878T3 PL 2928878 T3 PL2928878 T3 PL 2928878T3 PL 13792885 T PL13792885 T PL 13792885T PL 13792885 T PL13792885 T PL 13792885T PL 2928878 T3 PL2928878 T3 PL 2928878T3
Authority
PL
Poland
Prior art keywords
pyridin
fluoro
amine derivatives
derivatives containing
sulfoximine group
Prior art date
Application number
PL13792885T
Other languages
English (en)
Inventor
Ulrich Lücking
Niels Böhnke
Arne Scholz
Philip Lienau
Gerhard Siemeister
Ulf Bömer
Dirk Kosemund
Rolf Bohlmann
Ludwig Zorn
Original Assignee
Bayer Pharma Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharma Aktiengesellschaft filed Critical Bayer Pharma Aktiengesellschaft
Publication of PL2928878T3 publication Critical patent/PL2928878T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PL13792885T 2012-11-15 2013-11-12 Pochodne 5-fluoro-N -(pirydyn-2-ylo)pirydyno-2-aminy zawierające grupę sulfoksyiminową PL2928878T3 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP12192852 2012-11-15
EP13792885.9A EP2928878B1 (en) 2012-11-15 2013-11-12 5-fluoro-n-(pyridin-2-yl)pyridin-2-amine derivatives containing a sulfoximine group

Publications (1)

Publication Number Publication Date
PL2928878T3 true PL2928878T3 (pl) 2017-04-28

Family

ID=47148672

Family Applications (1)

Application Number Title Priority Date Filing Date
PL13792885T PL2928878T3 (pl) 2012-11-15 2013-11-12 Pochodne 5-fluoro-N -(pirydyn-2-ylo)pirydyno-2-aminy zawierające grupę sulfoksyiminową

Country Status (43)

Country Link
US (2) US9650340B2 (pl)
EP (1) EP2928878B1 (pl)
JP (1) JP6263193B2 (pl)
KR (1) KR102242871B1 (pl)
CN (1) CN105102444B (pl)
AP (1) AP3872A (pl)
AR (1) AR093505A1 (pl)
AU (1) AU2013346939B2 (pl)
BR (1) BR112015010707B1 (pl)
CA (1) CA2891358C (pl)
CL (1) CL2015001304A1 (pl)
CR (1) CR20150256A (pl)
CU (1) CU20150052A7 (pl)
CY (1) CY1118441T1 (pl)
DK (1) DK2928878T3 (pl)
DO (1) DOP2015000118A (pl)
EA (1) EA027226B1 (pl)
EC (1) ECSP15019323A (pl)
ES (1) ES2612978T3 (pl)
HK (1) HK1213255A1 (pl)
HR (1) HRP20161547T1 (pl)
HU (1) HUE032868T2 (pl)
IL (1) IL238322A (pl)
JO (1) JO3332B1 (pl)
LT (1) LT2928878T (pl)
MA (1) MA38090B1 (pl)
ME (1) ME02880B (pl)
MX (1) MX2015006169A (pl)
MY (1) MY170609A (pl)
NZ (1) NZ707084A (pl)
PE (1) PE20151071A1 (pl)
PH (1) PH12015501003B1 (pl)
PL (1) PL2928878T3 (pl)
PT (1) PT2928878T (pl)
RS (1) RS55580B1 (pl)
SG (1) SG11201503079PA (pl)
SI (1) SI2928878T1 (pl)
SV (1) SV2015004979A (pl)
TN (1) TN2015000185A1 (pl)
TW (1) TWI613193B (pl)
UA (1) UA115254C2 (pl)
UY (1) UY35141A (pl)
WO (1) WO2014076091A1 (pl)

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PL3601253T3 (pl) 2017-03-28 2022-01-17 Bayer Aktiengesellschaft Nowe hamujące ptefb związki makrocykliczne
CA3057891A1 (en) 2017-03-28 2018-10-04 Bayer Aktiengesellschaft Novel ptefb inhibiting macrocyclic compounds
JP7280286B2 (ja) 2018-02-13 2023-05-23 バイエル アクチェンゲゼルシャフト びまん性大細胞型ｂ細胞リンパ腫を治療するための５－フルオロ－４－（４－フルオロ－２－メトキシフェニル）－ｎ－｛４－［（ｓ－メチルスルホンイミドイル）メチル］ピリジン－２－イル｝ピリジン－２－アミンの使用
JP2023505850A (ja) 2019-12-09 2023-02-13 石薬集団中奇制薬技術（石家庄）有限公司 サイクリン依存性キナーゼ９阻害剤としての化合物及びその用途
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JP6371385B2 (ja) 2013-07-04 2018-08-08 バイエル ファーマ アクチエンゲゼルシャフト スルホキシイミン置換５−フルオロ−ｎ−（ピリジン−２−イル）ピリジン−２−アミン誘導体およびそのｃｄｋ９キナーゼ阻害薬としての使用
US9856242B2 (en) 2014-03-13 2018-01-02 Bayer Pharma Aktiengesellscaft 5-fluoro-N-(pyridin-2-yl)pyridin-2-amine derivatives containing a sulfone group

Also Published As

Publication number Publication date
EP2928878B1 (en) 2016-11-02
HUE032868T2 (en) 2017-11-28
CU20150052A7 (es) 2015-09-29
IL238322A (en) 2017-08-31
MX2015006169A (es) 2015-08-10
ES2612978T3 (es) 2017-05-19
CN105102444B (zh) 2017-08-01
TN2015000185A1 (en) 2016-10-03
PT2928878T (pt) 2017-02-08
US9877954B2 (en) 2018-01-30
AU2013346939A1 (en) 2015-05-14
WO2014076091A1 (en) 2014-05-22
UA115254C2 (uk) 2017-10-10
JP6263193B2 (ja) 2018-01-17
BR112015010707A8 (pt) 2019-10-01
CY1118441T1 (el) 2017-06-28
CA2891358A1 (en) 2014-05-22
LT2928878T (lt) 2016-11-25
US20150291528A1 (en) 2015-10-15
MA38090B1 (fr) 2018-09-28
KR102242871B1 (ko) 2021-04-20
ECSP15019323A (es) 2016-01-29
BR112015010707A2 (pt) 2017-07-11
CN105102444A (zh) 2015-11-25
PH12015501003A1 (en) 2015-07-27
AP2015008432A0 (en) 2015-05-31
JP2015537015A (ja) 2015-12-24
EA201590890A1 (ru) 2015-11-30
EA027226B1 (ru) 2017-07-31
NZ707084A (en) 2019-09-27
SI2928878T1 (sl) 2016-12-30
AP3872A (en) 2016-10-31
DOP2015000118A (es) 2015-06-15
PH12015501003B1 (en) 2015-07-27
CA2891358C (en) 2021-05-18
TWI613193B (zh) 2018-02-01
SG11201503079PA (en) 2015-06-29
CR20150256A (es) 2015-07-01
MY170609A (en) 2019-08-20
MA38090A1 (fr) 2018-02-28
SV2015004979A (es) 2017-01-30
AR093505A1 (es) 2015-06-10
BR112015010707B1 (pt) 2022-05-17
JO3332B1 (ar) 2019-03-13
PE20151071A1 (es) 2015-08-19
HRP20161547T1 (hr) 2016-12-30
DK2928878T3 (en) 2016-12-19
IL238322A0 (en) 2015-06-30
AU2013346939B2 (en) 2017-06-08
ME02880B (me) 2018-04-20
US9650340B2 (en) 2017-05-16
RS55580B1 (sr) 2017-06-30
KR20150084968A (ko) 2015-07-22
US20170202815A1 (en) 2017-07-20
UY35141A (es) 2014-06-30
CL2015001304A1 (es) 2015-07-17
HK1213255A1 (zh) 2016-06-30
EP2928878A1 (en) 2015-10-14
TW201420569A (zh) 2014-06-01

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