PE20240080A1 - Anticuerpos anti-hbv y metodos de uso - Google Patents

Anticuerpos anti-hbv y metodos de uso

Info

Publication number
PE20240080A1
PE20240080A1 PE2022002885A PE2022002885A PE20240080A1 PE 20240080 A1 PE20240080 A1 PE 20240080A1 PE 2022002885 A PE2022002885 A PE 2022002885A PE 2022002885 A PE2022002885 A PE 2022002885A PE 20240080 A1 PE20240080 A1 PE 20240080A1
Authority
PE
Peru
Prior art keywords
methods
hbv antibodies
antibodies
hbv
provides anti
Prior art date
Application number
PE2022002885A
Other languages
English (en)
Inventor
Maryline Bourgine
Maxime Beretta
Hugo Mouquet
Verena Hehle
Stanislas Pol
Helene Strick-Marchand
Malika Ait-Goughulte
Nadège Pelletier
Jens Fischer
Guy Georges
Tilman Schlothauer
Puijenbroek Erwin Van
Wouter Driessen
Original Assignee
Hoffmann La Roche
Pasteur Institut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche, Pasteur Institut filed Critical Hoffmann La Roche
Publication of PE20240080A1 publication Critical patent/PE20240080A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/082—Hepadnaviridae, e.g. hepatitis B virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Abstract

La invencion proporciona anticuerpos anti-S-HB y metodos para su uso
PE2022002885A 2020-06-08 2021-06-08 Anticuerpos anti-hbv y metodos de uso PE20240080A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20305612 2020-06-08
PCT/EP2021/065260 WO2021249990A2 (en) 2020-06-08 2021-06-08 Anti-hbv antibodies and methods of use

Publications (1)

Publication Number Publication Date
PE20240080A1 true PE20240080A1 (es) 2024-01-16

Family

ID=71614786

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2022002885A PE20240080A1 (es) 2020-06-08 2021-06-08 Anticuerpos anti-hbv y metodos de uso

Country Status (17)

Country Link
US (1) US20230340081A1 (es)
EP (1) EP4161644A2 (es)
JP (1) JP2023527918A (es)
KR (1) KR20230020975A (es)
CN (1) CN115697489A (es)
AR (1) AR122569A1 (es)
AU (1) AU2021288916A1 (es)
BR (1) BR112022024996A2 (es)
CA (1) CA3184495A1 (es)
CL (1) CL2022003288A1 (es)
CO (1) CO2022019225A2 (es)
CR (1) CR20220659A (es)
IL (1) IL298302A (es)
MX (1) MX2022015206A (es)
PE (1) PE20240080A1 (es)
TW (1) TW202204396A (es)
WO (1) WO2021249990A2 (es)

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Also Published As

Publication number Publication date
TW202204396A (zh) 2022-02-01
CL2022003288A1 (es) 2023-05-12
WO2021249990A3 (en) 2022-02-10
AU2021288916A1 (en) 2022-11-24
WO2021249990A2 (en) 2021-12-16
IL298302A (en) 2023-01-01
KR20230020975A (ko) 2023-02-13
JP2023527918A (ja) 2023-06-30
AR122569A1 (es) 2022-09-21
EP4161644A2 (en) 2023-04-12
CN115697489A (zh) 2023-02-03
MX2022015206A (es) 2023-01-05
CO2022019225A2 (es) 2023-03-17
CR20220659A (es) 2023-08-21
US20230340081A1 (en) 2023-10-26
BR112022024996A2 (pt) 2022-12-27
CA3184495A1 (en) 2021-12-16

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