CR20220659A - Anticuerpos anti-hbv y metodos de uso - Google Patents

Anticuerpos anti-hbv y metodos de uso

Info

Publication number
CR20220659A
CR20220659A CR20220659A CR20220659A CR20220659A CR 20220659 A CR20220659 A CR 20220659A CR 20220659 A CR20220659 A CR 20220659A CR 20220659 A CR20220659 A CR 20220659A CR 20220659 A CR20220659 A CR 20220659A
Authority
CR
Costa Rica
Prior art keywords
methods
hbv antibodies
antibodies
hbv
same
Prior art date
Application number
CR20220659A
Other languages
English (en)
Inventor
Guy Georges
Stanislas Pol
Hugo Mouquet
Jens Fischer
Maxime Beretta
Hélène Strick-Marchand
Malika Ait-Goughoulte
Wouter Driessen
Maryline Bourgine
Nadège Pelletier
Tilman Schlothauer
Puijenbroek Erwin Van
Verena Hehle
Original Assignee
Hoffmann La Roche
Pasteur Institut
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche, Pasteur Institut filed Critical Hoffmann La Roche
Publication of CR20220659A publication Critical patent/CR20220659A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/082Hepadnaviridae, e.g. hepatitis B virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/42Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52Constant or Fc region; Isotype
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Abstract

La invención proporciona anticuerpos anti-S-HB y métodos para su uso
CR20220659A 2020-06-08 2021-06-08 Anticuerpos anti-hbv y metodos de uso CR20220659A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP20305612 2020-06-08
PCT/EP2021/065260 WO2021249990A2 (en) 2020-06-08 2021-06-08 Anti-hbv antibodies and methods of use

Publications (1)

Publication Number Publication Date
CR20220659A true CR20220659A (es) 2023-08-21

Family

ID=71614786

Family Applications (1)

Application Number Title Priority Date Filing Date
CR20220659A CR20220659A (es) 2020-06-08 2021-06-08 Anticuerpos anti-hbv y metodos de uso

Country Status (17)

Country Link
US (1) US20230340081A1 (es)
EP (1) EP4161644A2 (es)
JP (1) JP2023527918A (es)
KR (1) KR20230020975A (es)
CN (1) CN115697489A (es)
AR (1) AR122569A1 (es)
AU (1) AU2021288916A1 (es)
BR (1) BR112022024996A2 (es)
CA (1) CA3184495A1 (es)
CL (1) CL2022003288A1 (es)
CO (1) CO2022019225A2 (es)
CR (1) CR20220659A (es)
IL (1) IL298302A (es)
MX (1) MX2022015206A (es)
PE (1) PE20240080A1 (es)
TW (1) TW202204396A (es)
WO (1) WO2021249990A2 (es)

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Also Published As

Publication number Publication date
US20230340081A1 (en) 2023-10-26
WO2021249990A3 (en) 2022-02-10
IL298302A (en) 2023-01-01
CA3184495A1 (en) 2021-12-16
TW202204396A (zh) 2022-02-01
KR20230020975A (ko) 2023-02-13
AU2021288916A1 (en) 2022-11-24
BR112022024996A2 (pt) 2022-12-27
JP2023527918A (ja) 2023-06-30
CN115697489A (zh) 2023-02-03
WO2021249990A2 (en) 2021-12-16
AR122569A1 (es) 2022-09-21
PE20240080A1 (es) 2024-01-16
CL2022003288A1 (es) 2023-05-12
EP4161644A2 (en) 2023-04-12
CO2022019225A2 (es) 2023-03-17
MX2022015206A (es) 2023-01-05

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