US3361306A
(en)
|
1966-03-31 |
1968-01-02 |
Merck & Co Inc |
Aerosol unit dispensing uniform amounts of a medically active ingredient
|
US3565070A
(en)
|
1969-02-28 |
1971-02-23 |
Riker Laboratories Inc |
Inhalation actuable aerosol dispenser
|
FR2224175B1
(es)
|
1973-04-04 |
1978-04-14 |
Isf Spa |
|
US4069819A
(en)
|
1973-04-13 |
1978-01-24 |
Societa Farmaceutici S.P.A. |
Inhalation device
|
IT1017153B
(it)
|
1974-07-15 |
1977-07-20 |
Isf Spa |
Apparecchio per inalazioni
|
SE438261B
(sv)
|
1981-07-08 |
1985-04-15 |
Draco Ab |
Anvendning i dosinhalator av ett perforerat membran
|
US4805811A
(en)
|
1985-03-29 |
1989-02-21 |
Aktiebolaget Draco |
Dosage device
|
SE448277B
(sv)
|
1985-04-12 |
1987-02-09 |
Draco Ab |
Indikeringsanordning vid en doseringsanordning for lekemedel
|
US4965288A
(en)
|
1988-02-25 |
1990-10-23 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
US4943593A
(en)
|
1988-02-25 |
1990-07-24 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
US5021456A
(en)
|
1988-02-25 |
1991-06-04 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
US5252608A
(en)
|
1988-02-25 |
1993-10-12 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
US5059714A
(en)
|
1988-02-25 |
1991-10-22 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
US5182297A
(en)
|
1988-02-25 |
1993-01-26 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
US5120764A
(en)
|
1988-11-01 |
1992-06-09 |
Merrell Dow Pharmaceuticals Inc. |
Inhibitors of lysyl oxidase
|
IT1228459B
(it)
|
1989-02-23 |
1991-06-19 |
Phidea S R L |
Inalatore con svuotamento regolare e completo della capsula.
|
US4955371A
(en)
|
1989-05-08 |
1990-09-11 |
Transtech Scientific, Inc. |
Disposable inhalation activated, aerosol device for pulmonary medicine
|
US4997854A
(en)
|
1989-08-25 |
1991-03-05 |
Trustees Of Boston University |
Anti-fibrotic agents and methods for inhibiting the activity of lysyl oxidase in-situ using adjacently positioned diamine analogue substrates
|
US20030125519A1
(en)
|
1990-08-27 |
2003-07-03 |
Peter Besmer |
Ligand for the c-kit receptor and methods of use thereof
|
US6319494B1
(en)
|
1990-12-14 |
2001-11-20 |
Cell Genesys, Inc. |
Chimeric chains for receptor-associated signal transduction pathways
|
DE4205148A1
(de)
|
1991-05-25 |
1993-01-21 |
Boehringer Mannheim Gmbh |
Monoklonale antikoerper gegen c-kit
|
ATE359842T1
(de)
|
1991-07-02 |
2007-05-15 |
Nektar Therapeutics |
Abgabevorrichtung für nebelförmige medikamente
|
IL104570A0
(en)
|
1992-03-18 |
1993-05-13 |
Yeda Res & Dev |
Chimeric genes and cells transformed therewith
|
US5261538A
(en)
|
1992-04-21 |
1993-11-16 |
Glaxo Inc. |
Aerosol testing method
|
US5785049A
(en)
|
1994-09-21 |
1998-07-28 |
Inhale Therapeutic Systems |
Method and apparatus for dispersion of dry powder medicaments
|
WO1994007498A1
(en)
*
|
1992-10-07 |
1994-04-14 |
Sumitomo Pharmaceuticals Company, Limited |
Pharmaceutical composition for inhibiting tumor necrosis factor production
|
US5388572A
(en)
|
1993-10-26 |
1995-02-14 |
Tenax Corporation (A Connecticut Corp.) |
Dry powder medicament inhalator having an inhalation-activated piston to aerosolize dose and deliver same
|
US5522385A
(en)
|
1994-09-27 |
1996-06-04 |
Aradigm Corporation |
Dynamic particle size control for aerosolized drug delivery
|
US5622163A
(en)
|
1994-11-29 |
1997-04-22 |
Iep Group, Inc. |
Counter for fluid dispensers
|
US5544647A
(en)
|
1994-11-29 |
1996-08-13 |
Iep Group, Inc. |
Metered dose inhalator
|
AU1583397A
(en)
|
1996-01-30 |
1997-08-22 |
Brigham And Women's Hospital |
Antibodies for modulating cd47-mediated neutrophil transmigration
|
CA2226962A1
(en)
|
1998-02-16 |
1999-08-16 |
Marie Sarfati |
Use of binding agents to cd47 and its ligands in the treatment or the prophylaxis of various inflammatory, autoimmune and allergic diseases and in the treatment of graft rejection
|
US6116234A
(en)
|
1999-02-01 |
2000-09-12 |
Iep Pharmaceutical Devices Inc. |
Metered dose inhaler agitator
|
EP1244707A1
(de)
|
1999-11-30 |
2002-10-02 |
Eberhard-Karls-Universität Tübingen Universitätsklinikum |
Antikörper gegen signal-regulator-proteine
|
US7658921B2
(en)
|
2000-12-12 |
2010-02-09 |
Medimmune, Llc |
Molecules with extended half-lives, compositions and uses thereof
|
US7282556B2
(en)
|
2001-05-15 |
2007-10-16 |
Emory University |
Polynucleotides and polypeptides relating to the modulation of SIRPα-CD47
|
FR2828206B1
(fr)
|
2001-08-03 |
2004-09-24 |
Centre Nat Rech Scient |
Utilisation d'inhibiteurs des lysyl oxydases pour la culture cellulaire et le genie tissulaire
|
US7317091B2
(en)
|
2002-03-01 |
2008-01-08 |
Xencor, Inc. |
Optimized Fc variants
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
US7662925B2
(en)
|
2002-03-01 |
2010-02-16 |
Xencor, Inc. |
Optimized Fc variants and methods for their generation
|
US7446190B2
(en)
|
2002-05-28 |
2008-11-04 |
Sloan-Kettering Institute For Cancer Research |
Nucleic acids encoding chimeric T cell receptors
|
US20090010920A1
(en)
|
2003-03-03 |
2009-01-08 |
Xencor, Inc. |
Fc Variants Having Decreased Affinity for FcyRIIb
|
US8388955B2
(en)
|
2003-03-03 |
2013-03-05 |
Xencor, Inc. |
Fc variants
|
EP1604665B1
(en)
|
2003-03-10 |
2011-05-11 |
Eisai R&D Management Co., Ltd. |
C-kit kinase inhibitor
|
WO2004096286A2
(en)
|
2003-04-25 |
2004-11-11 |
Gilead Sciences, Inc. |
Antiviral phosphonate analogs
|
AU2004268621C1
(en)
|
2003-08-29 |
2011-08-18 |
Exelixis, Inc. |
c-Kit modulators and methods of use
|
CN101133083A
(zh)
|
2003-11-11 |
2008-02-27 |
中外制药株式会社 |
人源化的抗cd47抗体
|
ES2605792T3
(es)
|
2004-05-13 |
2017-03-16 |
Icos Corporation |
Quinazolinona usada como inhibidor de la fosfatidilinositol 3-quinasa delta humana
|
WO2006009755A2
(en)
|
2004-06-17 |
2006-01-26 |
Plexxikon, Inc. |
Azaindoles modulating c-kit activity and uses therefor
|
DK2258376T3
(en)
|
2004-07-27 |
2019-04-15 |
Gilead Sciences Inc |
Phosphonate analogues of HIV inhibitor compounds
|
US7442716B2
(en)
|
2004-12-17 |
2008-10-28 |
Merck Frosst Canada Ltd. |
2-(phenyl or heterocyclic)-1H-phenantrho[9,10-d]imidazoles as mPGES-1 inhibitors
|
WO2006063466A1
(en)
|
2004-12-17 |
2006-06-22 |
Merck Frosst Canada Ltd. |
2-(phenyl or heterocyclic)-1h-phenantrho[9,10-d]imidazoles as mpges-1 inhibitors
|
US20090142345A1
(en)
|
2005-03-15 |
2009-06-04 |
Takeda Pharmaceutical Company Limited |
Prophylactic/therapeutic agent for cancer
|
AU2006247315A1
(en)
|
2005-05-18 |
2006-11-23 |
Wyeth |
4, 6-diamino-[1,7] naphthyridine-3-carbonitrile inhibitors of Tpl2 kinase and methods of making and using the same
|
EP1888529A2
(en)
|
2005-05-18 |
2008-02-20 |
Wyeth |
3-cyanoquinoline inhibitors of tpl2 kinase and methods of making and using the same
|
TWI404537B
(zh)
|
2005-08-19 |
2013-08-11 |
Array Biopharma Inc |
作為類鐸受體(toll-like receptor)調節劑之8-經取代苯并氮雜呯
|
TWI382019B
(zh)
|
2005-08-19 |
2013-01-11 |
Array Biopharma Inc |
作為類鐸受體(toll-like receptor)調節劑之胺基二氮雜呯
|
DK1931709T3
(en)
|
2005-10-03 |
2017-03-13 |
Xencor Inc |
FC VARIETIES WITH OPTIMIZED FC RECEPTOR BINDING PROPERTIES
|
KR100788161B1
(ko)
|
2006-01-06 |
2007-12-21 |
(주)아모레퍼시픽 |
벤즈이미다졸 아민 유도체 또는 아미노퀴놀린 유도체를 함유하는 피부 미백용 조성물
|
TW200740776A
(en)
|
2006-02-06 |
2007-11-01 |
Osi Pharm Inc |
N-phenylbenzotriazolyl c-kit inhibitors
|
JP5422204B2
(ja)
|
2006-03-30 |
2014-02-19 |
国立大学法人 千葉大学 |
DGKα阻害剤を含有する抗癌剤
|
TWI395754B
(zh)
|
2006-04-24 |
2013-05-11 |
Amgen Inc |
人類化之c-kit抗體
|
US20090192158A1
(en)
|
2006-05-02 |
2009-07-30 |
Stacia Kargman |
Methods for Treating or Preventing Neoplasias
|
JP2009537145A
(ja)
|
2006-05-15 |
2009-10-29 |
バイラル ロジック システムズ テクノロジー コーポレーション |
免疫学的疾患および障害を治療するためのcd47と関連した組成物および方法
|
DK2032156T3
(da)
|
2006-05-22 |
2013-02-18 |
Univ California |
Sammensætninger og fremgangsmåder til levering af oxygen
|
ITMI20061053A1
(it)
|
2006-05-30 |
2007-11-30 |
Manuli Rubber Ind Spa |
Raccordo per tubi flessibili per applicazioni oleodinamiche,industriali e aria condizionata,avente caratteristiche di tenuta migliorate.
|
US20090281115A1
(en)
|
2006-06-30 |
2009-11-12 |
Board of Regents, The University of Texas System, a Texas University |
Inhibitors of c-kit and uses thereof
|
WO2008011045A2
(en)
*
|
2006-07-18 |
2008-01-24 |
Cytovia, Inc. |
3-ARYL-6-ARYL-7H-[1,2,4]TRIAZOLO[3,4-b][1,3,4]THIADIAZINES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS AND THE USE THEREOF
|
NZ576279A
(en)
*
|
2006-10-19 |
2011-12-22 |
Signal Pharm Llc |
Heteroaryl compounds, compositions thereof, and use thereof as protein kinase inhibitors
|
DE102006058450A1
(de)
|
2006-12-12 |
2008-06-19 |
Eberhard-Karls-Universität Tübingen |
Zubereitungen zur Hemmung der Prostaglandin E2 Synthese
|
PT2170888E
(pt)
|
2007-06-29 |
2015-08-21 |
Gilead Sciences Inc |
Purina derivados e sua utilização como moduladores de recetor de tipo toll 7
|
AU2008310263B2
(en)
|
2007-10-11 |
2014-09-11 |
University Health Network |
Modulation of SIRPALPHA - CD47 interaction for increasing human hematopoietic stem cell engraftment and compounds therefor
|
TW200930368A
(en)
|
2007-11-15 |
2009-07-16 |
Astrazeneca Ab |
Bis-(sulfonylamino) derivatives in therapy
|
TW200930369A
(en)
|
2007-11-15 |
2009-07-16 |
Astrazeneca Ab |
Bis-(sulfonylamino) derivatives in therapy
|
CN101918365B
(zh)
|
2007-11-16 |
2013-10-09 |
吉联亚科学股份有限公司 |
人类免疫缺陷病毒复制的抑制剂
|
US20090163586A1
(en)
|
2007-12-20 |
2009-06-25 |
Astrazeneca Ab |
Bis-(Sulfonylamino) Derivatives in Therapy 205
|
WO2009103778A1
(en)
|
2008-02-19 |
2009-08-27 |
Novasaid Ab |
Compounds and methods
|
WO2009117987A2
(de)
|
2008-03-26 |
2009-10-01 |
Universität Tübingen |
Verwendung von boswelliasäuren und synthetischen boswelliasäurederivaten zur hemmung der mikrosomalen prostaglandin e2 synthase und des cathepsin g
|
US8324241B2
(en)
*
|
2008-04-11 |
2012-12-04 |
Bristol-Myers Squibb Company |
Triazolo compounds useful as DGAT1 inhibitors
|
WO2009130242A1
(en)
|
2008-04-23 |
2009-10-29 |
Novasaid Ab |
Low molecular weight derivatives and use thereof in treatment of prostaglandin e synthase related diseases
|
EP2119705A1
(en)
|
2008-05-14 |
2009-11-18 |
AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.p.A. |
3-Aminocarbozole compound, pharmaceutical composition containing it and preparation method therefor
|
DE102008027331A1
(de)
|
2008-06-07 |
2009-12-10 |
Friedrich-Alexander-Universität Erlangen-Nürnberg |
Verwendung von Indol-3-carbonsäureestern zur Hemmung der mikrosomalen Prostaglandin E2 Synthase
|
DE102008015432A1
(de)
|
2008-06-12 |
2009-12-17 |
Eberhard-Karls-Universität Tübingen |
Verwendung von Pirinixinsäure-Derivaten zur Hemmung der Prostaglandin E2 Synthese
|
US8242106B2
(en)
|
2008-08-01 |
2012-08-14 |
Ventirx Pharmaceuticals, Inc. |
Toll-like receptor agonist formulations and their use
|
WO2010019702A2
(en)
|
2008-08-12 |
2010-02-18 |
Oncomed Pharmaceuticals, Inc. |
Ddr1-binding agents and methods of use thereof
|
UY32138A
(es)
|
2008-09-25 |
2010-04-30 |
Boehringer Ingelheim Int |
Amidas sustituidas del ácido 2-(2,6-dicloro-fenilamino)-6-fluoro-1-metil-1h-bencimidazol-5-carboxílico y sus sales farmacéuticamente aceptables
|
US8450321B2
(en)
|
2008-12-08 |
2013-05-28 |
Gilead Connecticut, Inc. |
6-(1H-indazol-6-yl)-N-[4-(morpholin-4-yl)phenyl]imidazo-[1,2-A]pyrazin-8-amine, or a pharmaceutically acceptable salt thereof, as a SYK inhibitor
|
NZ612380A
(en)
|
2008-12-09 |
2015-01-30 |
Gilead Sciences Inc |
Modulators of toll-like receptors
|
BRPI0923442A2
(pt)
|
2008-12-19 |
2016-01-12 |
Novartis Ag |
polipeptídeos solúveis para uso em tratamento de distúrbio autoimunes e inflamatórios.
|
WO2010083253A2
(en)
|
2009-01-14 |
2010-07-22 |
Viral Logic Systems Technology Corp. |
Cd47 related compositions and methods for treating immunological diseases and disorders
|
UY32470A
(es)
|
2009-03-05 |
2010-10-29 |
Boehringer Ingelheim Int |
Derivados de 2-{2-cloro-5-[(sustituido) metil]fenilamino} -1-metil]fenilamino}-1-metilbencimidazol-5-carboxamidas-n-(sustituidas) y sus sales fisiológicamente aceptables, composiciones conteniéndolos y aplicaciones
|
US8673307B1
(en)
|
2009-03-09 |
2014-03-18 |
The Rockefeller University |
HIV-1 anti-core neutralizing antibodies that target a conformational epitope within the ALPHA5-helix of GP120
|
US8338441B2
(en)
|
2009-05-15 |
2012-12-25 |
Gilead Sciences, Inc. |
Inhibitors of human immunodeficiency virus replication
|
TWI625121B
(zh)
|
2009-07-13 |
2018-06-01 |
基利科學股份有限公司 |
調節細胞凋亡信號之激酶的抑制劑
|
EP2467377B1
(en)
|
2009-08-18 |
2016-12-28 |
Ventirx Pharmaceuticals, Inc. |
Substituted benzoazepines as toll-like receptor modulators
|
EP2467380B1
(en)
|
2009-08-18 |
2016-11-30 |
Ventirx Pharmaceuticals, Inc. |
Substituted benzoazepines as toll-like receptor modulators
|
WO2011023812A1
(en)
|
2009-08-27 |
2011-03-03 |
Novasaid Ab |
Microsomal prostaglandin e synthase-1 (mpges1) inhibitors
|
PL2491035T3
(pl)
|
2009-10-22 |
2018-01-31 |
Gilead Sciences Inc |
Pochodne puryny lub deazapuryny przydatne do leczenia (między innymi) infekcji wirusowych
|
JP5579862B2
(ja)
|
2009-10-23 |
2014-08-27 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
ミクロソームプロスタグランジンe2シンターゼ−1のインヒビター
|
KR20120107122A
(ko)
|
2009-12-22 |
2012-09-28 |
노파르티스 아게 |
치료법에서 사용하기 위한 4가 cd47―항체 불변 영역 융합 단백질
|
WO2011139637A1
(en)
|
2010-05-03 |
2011-11-10 |
Philadelphia Health & Education Corporation |
Small-molecule modulators of hiv-1 capsid stability and methods thereof
|
JP6166177B2
(ja)
|
2010-05-14 |
2017-07-19 |
ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー |
Cd47に対するヒト化及びキメラモノクローナル抗体
|
WO2011146862A1
(en)
|
2010-05-21 |
2011-11-24 |
Bellicum Pharmaceuticals, Inc. |
Methods for inducing selective apoptosis
|
ES2634490T3
(es)
|
2010-07-02 |
2017-09-28 |
Gilead Sciences, Inc. |
Derivados de ácido napht-2-ylacetico para tratar el sida
|
WO2012003498A1
(en)
|
2010-07-02 |
2012-01-05 |
Gilead Sciences, Inc. |
2 -quinolinyl- acetic acid derivatives as hiv antiviral compounds
|
US8759537B2
(en)
|
2010-08-20 |
2014-06-24 |
Boehringer Ingelheim International Gmbh |
3H-imidazo [4, 5-C] pyridine-6-carboxamides as anti-inflammatory agents
|
US8586604B2
(en)
|
2010-08-20 |
2013-11-19 |
Boehringer Ingelheim International Gmbh |
Inhibitors of the microsomal prostaglandin E2 synthase-1
|
CN104530238B
(zh)
|
2010-08-27 |
2019-11-26 |
吉利德生物制剂公司 |
基质金属蛋白酶9的抗体
|
CN103237549A
(zh)
|
2010-10-01 |
2013-08-07 |
帆德制药股份有限公司 |
过敏性疾病的治疗方法
|
RU2603467C2
(ru)
|
2010-10-01 |
2016-11-27 |
Вентиркс Фармасьютикалз, Инк. |
Терапевтическое применение агониста tlr и комбинированная терапия
|
PT3214091T
(pt)
|
2010-12-09 |
2019-01-11 |
Univ Pennsylvania |
Utilização de células t modificadas por recetor de antigénio quimérico para tratar o cancro
|
US8466186B2
(en)
|
2010-12-10 |
2013-06-18 |
Boehringer Ingelheim International Gmbh |
Compounds
|
US8674113B2
(en)
|
2010-12-10 |
2014-03-18 |
Boehringer Ingelheim International Gmbh |
Compounds
|
US9096532B2
(en)
|
2010-12-13 |
2015-08-04 |
The Regents Of The University Of California |
Pyrazole inhibitors of COX-2 and sEH
|
AR084174A1
(es)
|
2010-12-21 |
2013-04-24 |
Lilly Co Eli |
Compuestos de imidazol-2-benzamida utiles para el tratamiento de osteoartritis y una composicion farmaceutica
|
EP2663550B1
(en)
|
2011-01-12 |
2016-12-14 |
VentiRx Pharmaceuticals, Inc. |
Substituted benzoazepines as toll-like receptor modulators
|
US20140088085A1
(en)
|
2011-01-12 |
2014-03-27 |
Array Biopharma, Inc |
Substituted Benzoazepines As Toll-Like Receptor Modulators
|
WO2012110860A1
(en)
|
2011-02-17 |
2012-08-23 |
Glenmark Pharmaceuticals S.A. |
TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS
|
LT2694484T
(lt)
|
2011-04-08 |
2018-10-10 |
Janssen Sciences Ireland Uc |
Pirimidino dariniai, skirti virusinių infekcijų gydymui
|
PE20141066A1
(es)
|
2011-04-21 |
2014-09-05 |
Gilead Sciences Inc |
Compuestos de benzotiazol
|
WO2012154312A1
(en)
|
2011-05-09 |
2012-11-15 |
The United States Of America, As Represented By The Secretary, Department Of Health & Human Services |
Neutralizing antibodies to hiv-1 and their use
|
AR086044A1
(es)
|
2011-05-12 |
2013-11-13 |
Imclone Llc |
Anticuerpos que se unen especificamente a un dominio extracelular de c-kit y usos de los mismos
|
IL276182B
(en)
|
2011-05-17 |
2022-09-01 |
Univ Rockefeller |
Neutralizing antibodies against the human immunodeficiency virus and methods of using them
|
UA114476C2
(uk)
|
2011-05-18 |
2017-06-26 |
ЯНССЕН САЙЄНСІЗ АЙРЛЕНД ЮСі |
Хіназолінові похідні для лікування вірусних інфекцій та подальших захворювань
|
AR086254A1
(es)
|
2011-05-26 |
2013-11-27 |
Lilly Co Eli |
Derivados de imidazol utiles para el tratamiento de artritis
|
WO2012170250A1
(en)
|
2011-06-07 |
2012-12-13 |
Radiation Control Technologies, Inc. |
Morpholino oligonucleotides capable of inhibiting cd47-mediated cellular damage and uses thereof
|
JP6205354B2
(ja)
|
2011-07-06 |
2017-09-27 |
ギリアード サイエンシーズ, インコーポレイテッド |
Hivの処置のための化合物
|
CN102863512B
(zh)
|
2011-07-07 |
2016-04-20 |
上海泓博智源医药技术有限公司 |
抗病毒化合物
|
US9493549B2
(en)
|
2011-07-25 |
2016-11-15 |
The Rockefeller University |
Antibodies directed toward the HIV-1 GP120 CD4 binding site with increased potency and breadth
|
KR101778354B1
(ko)
|
2011-08-18 |
2017-09-13 |
니뽄 신야쿠 가부시키가이샤 |
헤테로환 유도체 및 의약
|
US9550835B2
(en)
|
2011-08-23 |
2017-01-24 |
Chugai Seiyaku Kabushiki Kaisha |
Anti-DDR1 antibody having anti-tumor activity
|
GB201115529D0
(en)
|
2011-09-08 |
2011-10-26 |
Imp Innovations Ltd |
Antibodies, uses and methods
|
US20140235643A1
(en)
|
2011-10-04 |
2014-08-21 |
Gilead Calistoga Llc |
Novel quinoxaline inhibitors of pi3k
|
US20140242095A1
(en)
|
2011-10-19 |
2014-08-28 |
University Health Network |
Antibodies and antibody fragments targeting sirp-alpha and their use in treating hematologic cancers
|
WO2013072825A1
(en)
|
2011-11-16 |
2013-05-23 |
Glenmark Pharmaceuticals S.A. |
Phtalazinone derivatives as mpegs -1 inhibitors
|
AU2012347453B2
(en)
|
2011-12-08 |
2017-11-23 |
The United States Of America, As Represented By The Secretary Department Of Health And Human Services |
Neutralizing antibodies to HIV-1 and their use
|
US9399645B2
(en)
|
2011-12-20 |
2016-07-26 |
Boehringer Ingelheim International Gmbh |
Inhibitors of HIV replication
|
EA037918B1
(ru)
|
2011-12-21 |
2021-06-07 |
Новира Терапьютикс, Инк. |
Противовирусные агенты против гепатита в
|
DK2804617T3
(da)
|
2012-01-17 |
2020-08-10 |
Univ Leland Stanford Junior |
Højaffine sirp-alpha-reagenser
|
UY34573A
(es)
|
2012-01-27 |
2013-06-28 |
Gilead Sciences Inc |
Inhibidor de la quinasa que regula la señal de la apoptosis
|
WO2013116562A1
(en)
|
2012-02-03 |
2013-08-08 |
Gilead Calistoga Llc |
Compositions and methods of treating a disease with (s)-4 amino-6-((1-(5-chloro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)ethyl)amino)pyrimidine-5-carbonitrile
|
EA034778B1
(ru)
|
2012-02-06 |
2020-03-19 |
Инхибркс, Инк. |
Антитела к cd47 и способы их применения
|
ES2716811T3
(es)
|
2012-02-08 |
2019-06-17 |
Janssen Sciences Ireland Unlimited Co |
Derivados piperidinopirimidínicos para el tratamiento de infecciones víricas
|
US9006257B2
(en)
|
2012-02-09 |
2015-04-14 |
Glenmark Pharmaceuticals S.A. |
Bicyclic compounds as mPGES-1 inhibitors
|
US20150044137A1
(en)
|
2012-03-23 |
2015-02-12 |
The United States of America, as represented by the Secretary, Dep. of Health Care Human Services |
Neutralizing antibodies to hiv-1 and their use
|
WO2013153535A1
(en)
|
2012-04-13 |
2013-10-17 |
Glenmark Pharmaceuticals S.A. |
TRICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS
|
ES2571479T3
(es)
|
2012-04-20 |
2016-05-25 |
Gilead Sciences Inc |
Derivados del ácido benzotiazol-6-il acético y su uso para tratar una infección por VIH
|
TWI568722B
(zh)
|
2012-06-15 |
2017-02-01 |
葛蘭馬克製藥公司 |
作爲mPGES-1抑制劑之***酮化合物
|
NZ703731A
(en)
|
2012-08-10 |
2018-03-23 |
Janssen Sciences Ireland Uc |
Alkylpyrimidine derivatives for the treatment of viral infections and further diseases
|
AU2013312477B2
(en)
|
2012-09-06 |
2018-05-31 |
Plexxikon Inc. |
Compounds and methods for kinase modulation, and indications therefor
|
PE20150776A1
(es)
|
2012-09-10 |
2015-05-21 |
Hoffmann La Roche |
6-aminoacido-heteroarildihidropirimidinas para el tratamiento y profilaxis de la infeccion del virus de la hepatitis b
|
TW201427995A
(zh)
|
2012-09-24 |
2014-07-16 |
Gilead Sciences Inc |
抗ddr1抗體
|
CN104837840B
(zh)
|
2012-10-10 |
2017-08-08 |
爱尔兰詹森科学公司 |
用于治疗病毒感染及其他疾病的吡咯并[3,2‑d]嘧啶衍生物
|
HUE051577T2
(hu)
|
2012-10-18 |
2021-03-01 |
Univ Rockefeller |
Széleskörû semlegesítést biztosító anti-HIV ellenanyagok
|
EP2911655A1
(en)
|
2012-10-24 |
2015-09-02 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Tpl2 kinase inhibitors for preventing or treating diabetes and for promoting -cell survival
|
EA035431B1
(ru)
|
2012-11-16 |
2020-06-15 |
Янссен Сайенсиз Айрлэнд Юси |
Гетероциклические замещенные производные 2-амино-хиназолина в качестве модуляторов tlr7 и/или tlr8 для лечения вирусных инфекций
|
RU2019118257A
(ru)
|
2012-12-03 |
2019-06-24 |
Новиммун С.А. |
Анти-cd47 антитела и способы их применения
|
WO2014089152A1
(en)
|
2012-12-04 |
2014-06-12 |
University Of Maryland, Baltimore |
Hiv-1 env-binding antibodies, fusion proteins, and methods of use
|
ES2786083T3
(es)
|
2012-12-12 |
2020-10-08 |
Arch Oncology Inc |
Anticuerpos terapéuticos CD47
|
SI2822954T1
(sl)
|
2012-12-21 |
2016-07-29 |
Gilead Sciences, Inc. |
Policiklične karbamoilpiridonske spojine in njihova farmacevtska uporaba
|
AU2013364068B2
(en)
|
2012-12-21 |
2016-10-20 |
Gilead Calistoga Llc |
Substituted pyrimidine aminoalkyl-quinazolones as phosphatidylinositol 3-kinase inhibitors
|
CA2895239C
(en)
|
2012-12-21 |
2020-10-27 |
Plexxikon Inc. |
Compounds and methods for kinase modulation, and indications therefor
|
ES2685568T3
(es)
|
2012-12-21 |
2018-10-10 |
Gilead Calistoga Llc |
Inhibidores de la isoquinolinona o quinazolinona fosfatidilinositol 3-quinasa
|
SG11201504982PA
(en)
|
2012-12-27 |
2015-07-30 |
Japan Tobacco Inc |
SUBSTITUTED SPIROPYRIDO[1,2-a]PYRAZINE DERIVATIVE AND MEDICINAL USE THEREOF AS HIV INTEGRASE INHIBITOR
|
CA2897018C
(en)
|
2013-01-07 |
2021-07-27 |
Omniox, Inc. |
Polymeric forms of h-nox proteins
|
AU2014220717B2
(en)
|
2013-02-21 |
2018-03-29 |
Janssen Sciences Ireland Uc |
2-aminopyrimidine derivatives for the treatment of viral infections
|
US8993771B2
(en)
|
2013-03-12 |
2015-03-31 |
Novira Therapeutics, Inc. |
Hepatitis B antiviral agents
|
WO2014167444A1
(en)
|
2013-04-08 |
2014-10-16 |
Glenmark Pharmaceuticals S.A. |
SUBSTITUTED BICYCLIC COMPOUNDS AS mPGES-1 INHIBITORS
|
EP3008053B1
(en)
|
2013-06-14 |
2018-03-21 |
Gilead Calistoga LLC |
Phosphatidylinositol 3-kinase inhibitors
|
PT3043865T
(pt)
|
2013-09-11 |
2021-01-14 |
Univ Claude Bernard Lyon |
Métodos e composições farmacêuticas para o tratamento da infeção por vírus da hepatite b
|
WO2015048462A1
(en)
|
2013-09-27 |
2015-04-02 |
Duke University |
Human monoclonal antibodies
|
US9751888B2
(en)
*
|
2013-10-04 |
2017-09-05 |
Infinity Pharmaceuticals, Inc. |
Heterocyclic compounds and uses thereof
|
WO2015059618A1
(en)
|
2013-10-22 |
2015-04-30 |
Glenmark Pharmaceuticals S.A. |
SUBSTITUTED PYRIMIDINE COMPOUNDS AS mPGES-1 INHIBITORS
|
US9290505B2
(en)
|
2013-12-23 |
2016-03-22 |
Gilead Sciences, Inc. |
Substituted imidazo[1,2-a]pyrazines as Syk inhibitors
|
WO2015103549A1
(en)
|
2014-01-03 |
2015-07-09 |
The United States Of America, As Represented By The Secretary Department Of Health And Human Services |
Neutralizing antibodies to hiv-1 env and their use
|
MX2016009828A
(es)
|
2014-01-30 |
2016-10-31 |
Hoffmann La Roche |
Nuevas dihidroquinolizinonas para el tratamiento y profilaxis de la infeccion por virus de la hepatitis b.
|
WO2015117008A2
(en)
|
2014-01-31 |
2015-08-06 |
The Rockefeller University |
Broadly neutralizing anti-hiv antibodies and epitope therefor
|
WO2015134536A1
(en)
|
2014-03-04 |
2015-09-11 |
Plexxikon Inc. |
Compounds and methods for kinase modulation, and indications therefor
|
RS58384B1
(sr)
|
2014-03-07 |
2019-04-30 |
Hoffmann La Roche |
Novi 6-fuzionisani heteroarildihidropirimidini za lečenje i profilaksu infekcije virusom hepatitisa b
|
US10081680B2
(en)
|
2014-03-11 |
2018-09-25 |
The Board Of Trustees Of The Leland Stanford Junior University |
Anti-SIRP-alpha antibodies and bispecific macrophage enhancing antibodies
|
CN106163521B
(zh)
|
2014-03-27 |
2021-02-09 |
艾科西斯有限责任公司 |
有效的可溶性环氧化物水解酶抑制剂
|
MX2016013158A
(es)
|
2014-04-10 |
2017-04-27 |
Seattle Children's Hospital (Dba Seattle Children's Res Institute) |
Productos de celulas t modificadas de genes de composicion definida.
|
MX368504B
(es)
|
2014-04-14 |
2019-10-04 |
Shanghai hengrui pharmaceutical co ltd |
Derivados de amidas y sales farmaceuticamente aceptables de los mismos, método de preparación de los mismos y aplicación médica de los mismos.
|
EP3143020B1
(en)
|
2014-05-13 |
2019-08-21 |
F. Hoffmann-La Roche AG |
Dihydroquinolizinones for the treatment and prophylaxis of hepatitis b virus infection
|
BR112016028814A2
(pt)
*
|
2014-06-13 |
2017-08-22 |
Gilead Sciences Inc |
?composição farmacêutica, métodos de tratamento de uma doença ou condição, de inibição de reações imunitárias ou crescimento excessivo ou destrutivo ou de proliferação de células cancerosas, kit, composto, um sal, um isômero, ou uma mistura farmaceuticamente aceitável do mesmo, e, uso de um composto, de um sal, de um isômero, ou de uma mistura farmaceuticamente aceitável do mesmo?
|
US10676521B2
(en)
|
2014-07-21 |
2020-06-09 |
The Rockefeller University |
Combination of broadly neutralizing HIV antibodies and viral inducers
|
WO2016012470A1
(en)
|
2014-07-25 |
2016-01-28 |
F. Hoffmann-La Roche Ag |
New amorphous and crystalline forms of (3s)-4-[[(4r)-4-(2-chloro-4-fluoro-phenyl)-5-methoxycarbonyl-2-thiazol-2-yl-1, 4-dihydropyrimidin-6-yl]methyl]morpholine-3-carboxylic acid
|
WO2016022971A1
(en)
|
2014-08-08 |
2016-02-11 |
The Board Of Trustees Of The Leland Stanford Junior University |
Sirp alpha-antibody fusion proteins
|
TWI702228B
(zh)
|
2014-08-08 |
2020-08-21 |
美商Alx腫瘤技術股份有限公司 |
信號調節蛋白α(signal-regulatory protein α, SIRP-α)變體構築物及其用途
|
KR101891933B1
(ko)
|
2014-08-14 |
2018-08-24 |
에프. 호프만-라 로슈 아게 |
B형 간염 바이러스 감염의 치료 또는 예방을 위한 신규한 피리다존 및 트라이아진온
|
LT3180363T
(lt)
|
2014-08-15 |
2019-11-25 |
Merck Patent Gmbh |
Sirp-alfa imunoglobulino sulieti baltymai
|
TWI805109B
(zh)
|
2014-08-28 |
2023-06-11 |
美商奇諾治療有限公司 |
對cd19具專一性之抗體及嵌合抗原受體
|
JO3474B1
(ar)
|
2014-08-29 |
2020-07-05 |
Amgen Inc |
مشتقات تيتراهيدرونافثالين التي تثبط بروتين mcl-1
|
JO3581B1
(ar)
|
2014-10-29 |
2020-07-05 |
Lilly Co Eli |
مركبات ميثيل-بيبيريدين جديدة مفيدة لتثبيط إنزيم سينثاز -1 بروستاجلاندين e2 ميكروسومي
|
TW201627299A
(zh)
|
2014-10-29 |
2016-08-01 |
美國禮來大藥廠 |
用於抑制微粒體***素e合成酶1之新穎羧酸化合物
|
US9637485B2
(en)
|
2014-11-03 |
2017-05-02 |
Hoffmann-La Roche Inc. |
6,7-dihydrobenzo[a]quinolizin-2-one derivatives for the treatment and prophylaxis of hepatitis B virus infection
|
SG11201704058TA
(en)
|
2014-11-18 |
2017-06-29 |
Janssen Pharmaceutica Nv |
Cd47 antibodies, methods, and uses
|
KR20170087514A
(ko)
|
2014-12-03 |
2017-07-28 |
주노 쎄러퓨티크스 인코퍼레이티드 |
입양 세포 치료를 위한 방법 및 조성물
|
WO2016090300A1
(en)
|
2014-12-05 |
2016-06-09 |
Genentech, Inc. |
Methods and compositions for treating cancer using pd-1 axis antagonists and hpk1 antagonists
|
EP3234144B1
(en)
|
2014-12-15 |
2020-08-26 |
Bellicum Pharmaceuticals, Inc. |
Methods for controlled elimination of therapeutic cells
|
US9676793B2
(en)
|
2014-12-23 |
2017-06-13 |
Hoffmann-Laroche Inc. |
Co-crystals of 5-amino-2-oxothiazolo[4,5-d]pyrimidin-3(2H)-yl-5-hydroxymethyl tetrahydrofuran-3-yl acetate and methods for preparing and using the same
|
WO2016102438A1
(en)
|
2014-12-23 |
2016-06-30 |
F. Hoffmann-La Roche Ag |
Process for the preparation of 4-phenyl-5-alkoxycarbonyl-2-thiazol-2-yl-1,4-dihydropyrimidine analogues
|
EP3240537B1
(en)
|
2014-12-30 |
2020-09-09 |
F. Hoffmann-La Roche AG |
Novel tetrahydropyridopyrimidines and tetrahydropyridopyridines for the treatment and prophylaxis of hepatitis b virus infection
|
US10870699B2
(en)
|
2014-12-30 |
2020-12-22 |
Celgene Corporation |
Anti-CD47 antibodies and uses thereof
|
CN107109497A
(zh)
|
2014-12-31 |
2017-08-29 |
豪夫迈·罗氏有限公司 |
通过实时PCR从细胞裂解物定量HBV cccDNA的高通量新方法
|
MA41338B1
(fr)
|
2015-01-16 |
2019-07-31 |
Hoffmann La Roche |
Composés de pyrazine pour le traitement de maladies infectieuses
|
WO2016120186A1
(en)
|
2015-01-27 |
2016-08-04 |
F. Hoffmann-La Roche Ag |
Recombinant hbv cccdna, the method to generate thereof and the use thereof
|
WO2016128335A1
(en)
|
2015-02-11 |
2016-08-18 |
F. Hoffmann-La Roche Ag |
Novel 2-oxo-6,7-dihydrobenzo[a]quinolizine-3-carboxylic acid derivatives for the treatment and prophylaxis of hepatitis b virus infection
|
AR103868A1
(es)
|
2015-03-04 |
2017-06-07 |
Sorrento Therapeutics Inc |
Anticuerpos anti-cd47 como agentes terapéuticos
|
CN107580499A
(zh)
|
2015-03-17 |
2018-01-12 |
欧姆尼奥克斯公司 |
通过蛋白质介导的o2递送调节肿瘤免疫性
|
WO2016149710A2
(en)
|
2015-03-19 |
2016-09-22 |
Duke University |
Hiv-1 neutralizing antibodies and uses thereof
|
PL3271389T3
(pl)
|
2015-03-20 |
2020-08-10 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizujące przeciwciała wiążące się z gp120 i ich stosowanie
|
WO2016179399A1
(en)
|
2015-05-06 |
2016-11-10 |
The Board Of Trustees Of The Leland Stanford Junior University |
High affinity cd47 analogs
|
US10259882B2
(en)
|
2015-05-07 |
2019-04-16 |
Agenus Inc. |
Anti-OX40 antibodies
|
CN104804093A
(zh)
|
2015-05-27 |
2015-07-29 |
江苏春申堂药业有限公司 |
一种针对cd47的单域抗体
|
JP6949728B2
(ja)
|
2015-05-29 |
2021-10-13 |
ジュノー セラピューティクス インコーポレイテッド |
遺伝子操作された細胞における阻害相互作用を調節するための組成物および方法
|
WO2016196975A1
(en)
|
2015-06-03 |
2016-12-08 |
The United States Of America, As Represented By The Secretary Department Of Health & Human Services |
Neutralizing antibodies to hiv-1 env and their use
|
US10618976B2
(en)
|
2015-06-16 |
2020-04-14 |
The Board Of Trustees Of The Leland Stanford Junior University |
SIRP-α agonist antibody
|
LT3322711T
(lt)
|
2015-06-25 |
2021-05-10 |
University Health Network |
Hpk1 inhibitoriai ir jų panaudojimo būdai
|
JP6898303B2
(ja)
|
2015-08-07 |
2021-07-07 |
エーエルエックス オンコロジー インコーポレイテッド |
Sirp−アルファドメインまたはそのバリアントを有する構築物
|
US10772962B2
(en)
*
|
2015-08-19 |
2020-09-15 |
Arvinas Operations, Inc. |
Compounds and methods for the targeted degradation of bromodomain-containing proteins
|
EP3350320A1
(en)
|
2015-09-17 |
2018-07-25 |
Novartis AG |
Car t cell therapies with enhanced efficacy
|
CN116425875A
(zh)
|
2015-09-18 |
2023-07-14 |
安驰肿瘤公司 |
治疗性cd47抗体
|
CN108290948B
(zh)
|
2015-09-21 |
2021-10-29 |
伊拉兹马斯大学医疗中心 |
抗-cd47抗体及使用方法
|
LT3371316T
(lt)
|
2015-11-04 |
2022-11-25 |
Hookipa Biotech Gmbh |
Vakcinos nuo hepatito b viruso
|
EP3383914A4
(en)
|
2015-12-02 |
2019-10-30 |
Agenus Inc. |
ANTI-OX40 ANTIBODIES AND METHODS OF USE
|
CA3007022A1
(en)
|
2015-12-02 |
2017-06-08 |
Agenus Inc. |
Anti-gitr antibodies and methods of use thereof
|
WO2017096221A1
(en)
|
2015-12-02 |
2017-06-08 |
The Rockefeller University |
Bispecific anti-hiv broadly neutralizing antibodies
|
US11447557B2
(en)
|
2015-12-02 |
2022-09-20 |
Agenus Inc. |
Antibodies and methods of use thereof
|
WO2017096276A1
(en)
|
2015-12-02 |
2017-06-08 |
Agenus Inc. |
Anti-gitr antibodies and methods of use thereof
|
CA3006963A1
(en)
|
2015-12-03 |
2017-06-08 |
Ludwig Institute For Cancer Research Ltd. |
Anti-ox40 antibodies and methods of use thereof
|
ES2952064T3
(es)
|
2015-12-16 |
2023-10-26 |
Walter & Eliza Hall Inst Medical Res |
Inhibición de la proteína SH2 inducida por citocinas en células NK
|
PT3402820T
(pt)
|
2016-01-11 |
2020-08-20 |
Forty Seven Inc |
Anticorpos monoclonais anti-cd47 quiméricos, de ratinho ou humanizados
|
CN107022027B
(zh)
|
2016-02-02 |
2022-03-08 |
中国疾病预防控制中心性病艾滋病预防控制中心 |
Hiv-1广谱中和抗体及其用途
|
CN107033241B
(zh)
|
2016-02-03 |
2022-03-08 |
中国疾病预防控制中心性病艾滋病预防控制中心 |
Hiv-1广谱中和抗体及其用途
|
WO2017147410A1
(en)
|
2016-02-25 |
2017-08-31 |
Amgen Inc. |
Compounds that inhibit mcl-1 protein
|
US10858338B2
(en)
|
2016-03-15 |
2020-12-08 |
The Regents Of The University Of California |
Inhibitors for soluble epoxide hydrolase (SEH) and fatty acid amide hydrolase (FAAH)
|
CN107286077B
(zh)
|
2016-04-01 |
2021-04-02 |
合肥中科普瑞昇生物医药科技有限公司 |
一种选择性的c-kit激酶抑制剂
|
CN109071664B
(zh)
|
2016-04-14 |
2023-02-21 |
Ose免疫疗法 |
新型抗-SIRPa抗体及其治疗应用
|
JP2019518742A
(ja)
|
2016-05-09 |
2019-07-04 |
セルジーン コーポレーションCelgene Corporation |
Cd47抗体およびその使用方法
|
EP3243522A1
(en)
|
2016-05-10 |
2017-11-15 |
Université Pierre et Marie Curie (Paris 6) |
Agonist agents of cd47 inducing programmed cell death and their use in the treatments of diseases associated with defects in programmed cell death
|
US20190135875A1
(en)
|
2016-05-18 |
2019-05-09 |
Hookipa Biotech Gmbh |
Tri-segmented pichinde viruses as vaccine vectors
|
CN112250670B
(zh)
|
2016-06-07 |
2021-06-08 |
北京加科思新药研发有限公司 |
可用作shp2抑制剂的新型杂环衍生物
|
CN106084052B
(zh)
|
2016-06-17 |
2019-12-27 |
长春金赛药业股份有限公司 |
抗cd47单克隆抗体及其应用
|
JP6776378B2
(ja)
|
2016-06-30 |
2020-10-28 |
ギリアード サイエンシーズ, インコーポレイテッド |
Cotモジュレーターとしての4,6−ジアミノキナゾリン類およびその使用方法
|
EP3493845A4
(en)
|
2016-08-03 |
2020-04-15 |
The Board of Trustees of the Leland Stanford Junior University |
INTERRUPTION OF FC RECEPTOR USE ON MACROPHAGES TO IMPROVE THE EFFECTIVENESS OF ANTI-SIRPALPHA ANTIBODY THERAPY
|
AR109595A1
(es)
|
2016-09-09 |
2018-12-26 |
Incyte Corp |
Compuestos de pirazolopirimidina y usos de estos como inhibidores de hpk1
|
US20180072718A1
(en)
|
2016-09-09 |
2018-03-15 |
Incyte Corporation |
Pyrazolopyridine compounds and uses thereof
|
US10280164B2
(en)
|
2016-09-09 |
2019-05-07 |
Incyte Corporation |
Pyrazolopyridone compounds and uses thereof
|
AU2017322427B2
(en)
|
2016-09-09 |
2021-12-23 |
Incyte Corporation |
Pyrazolopyridine derivatives as HPK1 modulators and uses thereof for the treatment of cancer
|
JOP20190009A1
(ar)
|
2016-09-21 |
2019-01-27 |
Alx Oncology Inc |
أجسام مضادة ضد بروتين ألفا منظم للإشارات وطرق استخدامها
|
GB2605540B
(en)
|
2016-10-18 |
2022-12-21 |
Univ Minnesota |
Tumor infiltrating lymphocytes and methods of therapy
|
CA2999058C
(en)
|
2016-10-20 |
2024-03-12 |
I-Mab |
Novel cd47 monoclonal antibodies and uses thereof
|
WO2018075960A1
(en)
|
2016-10-21 |
2018-04-26 |
Tioma Therapeutics, Inc. |
Therapeutic cd47 antibodies
|
EP3538557A4
(en)
|
2016-11-08 |
2020-11-18 |
Ablexis, LLC |
ANTI-CD47 ANTIBODIES
|
MA46770A
(fr)
|
2016-11-09 |
2019-09-18 |
Agenus Inc |
Anticorps anti-ox40, anticorps anti-gitr, et leurs procédés d'utilisation
|
TW201819413A
(zh)
|
2016-11-28 |
2018-06-01 |
大陸商江蘇恆瑞醫藥股份有限公司 |
Cd47抗體、其抗原結合片段及其醫藥用途
|
JP7025426B2
(ja)
|
2016-11-30 |
2022-02-24 |
アリアド ファーマシューティカルズ, インコーポレイテッド |
造血前駆体キナーゼ1(hpk1)阻害剤としてのアニリノピリミジンas
|
KR102650524B1
(ko)
|
2016-12-09 |
2024-03-26 |
알렉터 엘엘씨 |
항-sirp-알파 항체 및 그의 사용 방법
|
EA201991197A1
(ru)
|
2016-12-15 |
2020-01-13 |
Ариад Фармасьютикалз, Инк. |
БЕНЗИМИДАЗОЛЬНЫЕ СОЕДИНЕНИЯ В КАЧЕСТВЕ ИНГИБИТОРОВ c-Kit
|
CN110291086B
(zh)
|
2016-12-15 |
2023-08-11 |
阿瑞雅德制药公司 |
作为c-kit抑制剂的氨基噻唑化合物
|
KR102607101B1
(ko)
|
2017-01-26 |
2023-11-29 |
제트엘아이피 홀딩 리미티드 |
Cd47 항원 결합 유닛 및 그것의 사용
|
WO2018167147A1
(en)
|
2017-03-15 |
2018-09-20 |
F. Hoffmann-La Roche Ag |
Azaindoles as inhibitors of hpk1
|
CA3057582C
(en)
|
2017-03-23 |
2024-01-09 |
Jacobio Pharmaceuticals Co., Ltd. |
Novel heterocyclic derivatives useful as shp2 inhibitors
|
BR112019018093A2
(pt)
|
2017-03-30 |
2020-06-16 |
F. Hoffmann-La Roche Ag |
Compostos, composição, método de inibição de hpk1, métodos para melhorar uma resposta imune e para tratar um distúrbio e usos do composto
|
WO2018183964A1
(en)
|
2017-03-30 |
2018-10-04 |
Genentech, Inc. |
Isoquinolines as inhibitors of hpk1
|
JP6453507B2
(ja)
|
2017-03-30 |
2019-01-16 |
アムジエン・インコーポレーテツド |
Mcl−1タンパク質を阻害する化合物
|
JP7160833B2
(ja)
|
2017-04-13 |
2022-10-25 |
サイロパ ビー.ブイ. |
抗sirpアルファ抗体
|
JOP20180040A1
(ar)
|
2017-04-20 |
2019-01-30 |
Gilead Sciences Inc |
مثبطات pd-1/pd-l1
|
RU2771174C2
(ru)
|
2017-05-16 |
2022-04-28 |
Байондис Б. В. |
АНТИ-SIRPα АНТИТЕЛА
|
CN109096395B
(zh)
|
2017-06-20 |
2022-06-24 |
华兰生物工程股份有限公司 |
阻断型cd47纳米抗体及其用途
|
WO2019005883A1
(en)
|
2017-06-26 |
2019-01-03 |
University Of Virginia Patent Foundation |
COMPOSITIONS AND USES THEREOF
|
EP3658589B1
(en)
|
2017-07-26 |
2023-09-27 |
Forty Seven, Inc. |
Anti-sirp-alpha antibodies and related methods
|
JP7262440B2
(ja)
|
2017-08-02 |
2023-04-21 |
フェインズ セラピューティクス,インコーポレーテッド |
抗cd47抗体及びその使用
|
RU2020109544A
(ru)
|
2017-08-18 |
2021-09-20 |
Ультрахьюман Фор Лимитед |
Связывающие агенты
|
CN109422811A
(zh)
|
2017-08-29 |
2019-03-05 |
信达生物制药(苏州)有限公司 |
抗cd47抗体及其用途
|
CN108503708B
(zh)
|
2017-09-01 |
2021-07-30 |
北京智仁美博生物科技有限公司 |
抗人cd47抗体及其用途
|
CN109422726B
(zh)
|
2017-09-04 |
2022-10-28 |
华东理工大学 |
CD47/SIRPα的阻断剂及其应用
|
US11274102B2
(en)
|
2017-10-30 |
2022-03-15 |
Glaxosmithkline Intellectual Property Development Limited |
Compounds useful in HIV therapy
|
JP2021500926A
(ja)
|
2017-11-01 |
2021-01-14 |
ハミングバード・バイオサイエンス・ホールディングス・プライベート・リミテッド |
Cd47抗原結合分子
|
KR102436084B1
(ko)
|
2017-11-24 |
2022-08-25 |
주식회사 젬백스앤카엘 |
신규 펩티드 및 이를 포함한 조성물
|
AR113862A1
(es)
|
2017-12-01 |
2020-06-17 |
Seattle Genetics Inc |
Anticuerpos anti-cd47 y sus usos para tratar cáncer
|
CA3087841A1
(en)
|
2018-01-12 |
2019-07-18 |
Aurigene Discovery Technologies Limited |
1,2,4-oxadiazole compounds as inhibitors of cd47 signalling pathways
|
CA3089512A1
(en)
|
2018-01-24 |
2019-08-01 |
Nanjing Legend Biotech Co., Ltd. |
Anti-cd47 antibodies that do not cause significant red blood cell agglutination
|
GB201802201D0
(en)
|
2018-02-09 |
2018-03-28 |
Ultrahuman Five Ltd |
Binding agents
|
EP4227302A1
(en)
|
2018-02-13 |
2023-08-16 |
Gilead Sciences, Inc. |
Pd-1/pd-l1 inhibitors
|
CN110144009B
(zh)
|
2018-02-14 |
2020-01-21 |
上海洛启生物医药技术有限公司 |
Cd47单域抗体及其用途
|
CA3093468A1
(en)
|
2018-03-09 |
2019-09-12 |
Agenus Inc. |
Anti-cd73 antibodies and methods of use thereof
|
EA202091859A1
(ru)
|
2018-03-13 |
2021-02-04 |
Осе Иммьюнотерапьютикс |
Применение антител к sirpa v1 человека и способ получения антител к sirpa v1
|
WO2019179366A1
(en)
|
2018-03-20 |
2019-09-26 |
Wuxi Biologics (Shanghai) Co. Ltd. |
Novel anti-cd47 antibodies
|
WO2019183266A1
(en)
|
2018-03-21 |
2019-09-26 |
ALX Oncology Inc. |
Antibodies against signal-regulatory protein alpha and methods of use
|
GB201804860D0
(en)
|
2018-03-27 |
2018-05-09 |
Ultrahuman Two Ltd |
CD47 Binding agents
|
CN110305212A
(zh)
|
2018-03-27 |
2019-10-08 |
信达生物制药(苏州)有限公司 |
抗cd47抗体及其用途
|
CN110386984B
(zh)
|
2018-04-17 |
2022-04-22 |
杭州尚健生物技术有限公司 |
结合cd47蛋白的融合蛋白及其应用
|
CA3099342A1
(en)
|
2018-05-03 |
2019-11-07 |
Board Of Regents, The University Of Texas System |
Natural killer cells engineered to express chimeric antigen receptors with immune checkpoint blockade
|
JP6899975B2
(ja)
|
2018-05-14 |
2021-07-07 |
ギリアード サイエンシーズ, インコーポレイテッド |
Mcl−1阻害剤
|
CN110577597B
(zh)
|
2018-06-11 |
2021-10-22 |
康诺亚生物医药科技(成都)有限公司 |
一种阻断CD47和SIRPα相互作用的抗体
|
CN112566662A
(zh)
|
2018-06-15 |
2021-03-26 |
阿库鲁斯生物科学公司 |
针对cd47的阻断抗体及其使用方法
|
EA202190137A1
(ru)
|
2018-06-27 |
2021-05-17 |
Бристол-Маерс Сквибб Компани |
Нафтиридиноновые соединения для применения в качестве активаторов t-клеток
|
DK3814348T3
(da)
|
2018-06-27 |
2023-10-30 |
Bristol Myers Squibb Co |
Substituerede naphthyridinonforbindelser, der er anvendelige som t-celleaktivatorer
|
EP3817769A4
(en)
|
2018-07-05 |
2022-03-30 |
Trican Biotechnology Co., Ltd |
HUMAN ANTI-CD47 ANTIBODIES AND THEIR USES
|
CN112673023B
(zh)
|
2018-07-10 |
2023-09-12 |
国立大学法人神户大学 |
抗SIRPα抗体
|
PT3820572T
(pt)
|
2018-07-13 |
2023-11-10 |
Gilead Sciences Inc |
Inibidores pd-1/pd-l1
|
WO2020019135A1
(zh)
|
2018-07-23 |
2020-01-30 |
中国科学院微生物研究所 |
一种抗cd47抗体及其应用
|
US20210324075A1
(en)
|
2018-08-13 |
2021-10-21 |
Arch Oncology, Inc. |
Therapeutic cd47 antibodies
|
CN110872350B
(zh)
|
2018-08-31 |
2023-04-07 |
南京圣和药业股份有限公司 |
抗cd47抗体及其应用
|
TW202028237A
(zh)
|
2018-09-27 |
2020-08-01 |
美商西建公司 |
SIRPα結合蛋白及其使用方法
|
KR20200040407A
(ko)
|
2018-10-10 |
2020-04-20 |
주식회사 노벨티노빌리티 |
신규 항-c-KIT 항체
|
MX2021005047A
(es)
|
2018-10-31 |
2021-09-08 |
Gilead Sciences Inc |
Compuestos de 6-azabenzimidazol sustituidos como inhibidores de hpk1.
|
WO2020092528A1
(en)
|
2018-10-31 |
2020-05-07 |
Gilead Sciences, Inc. |
Substituted 6-azabenzimidazole compounds having hpk1 inhibitory activity
|
AR119821A1
(es)
|
2019-08-28 |
2022-01-12 |
Bristol Myers Squibb Co |
Compuestos de piridopirimidinonilo sustituidos útiles como activadores de células t
|
WO2021105117A1
(en)
|
2019-11-28 |
2021-06-03 |
Bayer Aktiengesellschaft |
Substituted aminoquinolones as dgkalpha inhibitors for immune activation
|
WO2021105115A1
(en)
|
2019-11-28 |
2021-06-03 |
Bayer Aktiengesellschaft |
Substituted aminoquinolones as dgkalpha inhibitors for immune activation
|
CN115210238A
(zh)
|
2019-11-28 |
2022-10-18 |
拜耳公司 |
作为用于免疫激活的DGKα抑制剂的取代的氨基喹诺酮类
|
WO2021127554A1
(en)
|
2019-12-19 |
2021-06-24 |
Bristol-Myers Squibb Company |
Combinations of dgk inhibitors and checkpoint antagonists
|
IL294270A
(en)
|
2019-12-23 |
2022-08-01 |
Bristol Myers Squibb Co |
Substituted piperazine derivatives are useful as t-cell activators
|
JP2023507847A
(ja)
|
2019-12-23 |
2023-02-27 |
ブリストル-マイヤーズ スクイブ カンパニー |
T細胞アクティベーターとして有用な置換キナゾリニル化合物
|
AR120823A1
(es)
|
2019-12-23 |
2022-03-23 |
Bristol Myers Squibb Co |
Compuestos bicíclicos sustituidos útiles como activadores de células t
|
CN114846015A
(zh)
|
2019-12-23 |
2022-08-02 |
百时美施贵宝公司 |
用作t细胞激活剂的经取代的杂芳基化合物
|
US20230061608A1
(en)
|
2019-12-23 |
2023-03-02 |
Bristol-Myers Squibb Company |
Substituted quinolinonyl piperazine compounds useful as t cell activators
|
AR120896A1
(es)
|
2019-12-25 |
2022-03-30 |
Astellas Pharma Inc |
COMPUESTO DE PIRIDAZINIL-TIAZOLCARBOXAMIDA COMO INHIBIDORES DE DGKz
|
WO2021214019A1
(en)
|
2020-04-24 |
2021-10-28 |
Bayer Aktiengesellschaft |
Substituted aminothiazoles as dgkzeta inhibitors for immune activation
|
WO2021258010A1
(en)
|
2020-06-19 |
2021-12-23 |
Gossamer Bio Services, Inc. |
Oxime compounds useful as t cell activators
|
AU2021400725A1
(en)
|
2020-12-16 |
2023-08-03 |
Gossamer Bio Services, Inc. |
Compounds useful as t cell activators
|
WO2022271684A1
(en)
|
2021-06-23 |
2022-12-29 |
Gilead Sciences, Inc. |
Diacylglyercol kinase modulating compounds
|
EP4359411A1
(en)
|
2021-06-23 |
2024-05-01 |
Gilead Sciences, Inc. |
Diacylglyercol kinase modulating compounds
|
IL309378A
(en)
|
2021-06-23 |
2024-02-01 |
Gilead Sciences Inc |
DIACYLGLYERCOL KINASE MODULATING COMPOUNDS
|
CN117396478A
(zh)
|
2021-06-23 |
2024-01-12 |
吉利德科学公司 |
二酰基甘油激酶调节化合物
|