PE20170938A1 - Suministro al sistema nervioso central de agentes terapeuticos - Google Patents

Suministro al sistema nervioso central de agentes terapeuticos

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Publication number
PE20170938A1
PE20170938A1 PE2017000503A PE2017000503A PE20170938A1 PE 20170938 A1 PE20170938 A1 PE 20170938A1 PE 2017000503 A PE2017000503 A PE 2017000503A PE 2017000503 A PE2017000503 A PE 2017000503A PE 20170938 A1 PE20170938 A1 PE 20170938A1
Authority
PE
Peru
Prior art keywords
supply
therapeutic agents
nervous system
central nervous
sulfatase
Prior art date
Application number
PE2017000503A
Other languages
English (en)
Inventor
Jing Pan
Jan Powell
Lawrence Charnas
Teresa Leah Wright
Richard Pfeifer
Zahra Shahrokh
Pericles Calias
Thomas Mccauley
Original Assignee
Shire Human Genetic Therapies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=45352777&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20170938(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Shire Human Genetic Therapies filed Critical Shire Human Genetic Therapies
Publication of PE20170938A1 publication Critical patent/PE20170938A1/es

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    • C12Y310/01001—N-Sulfoglucosamine sulfohydrolase (3.10.1.1)

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  • Health & Medical Sciences (AREA)
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Abstract

Se refiere a una composicion farmaceutica que comprende una enzima lisosomal a una concentracion de o mayor que 10mg/mL y un agente amortiguador, que comprende fosfato a una concentracion de hasta 50mM, donde la enzima lisosomal se selecciona de iduronato-2-sulfatasa recombinante (I2S), arilsulfatasa A (ASA), heparan N-sulfatasa (HNS), alfa-N-acetilglucosaminidasa (Naglu) y beta-galactosidasa (GLC). Dicha composicion es util en el tratamiento de trastornos de almacenamiento lisosomal
PE2017000503A 2010-06-25 2011-06-25 Suministro al sistema nervioso central de agentes terapeuticos PE20170938A1 (es)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US35885710P 2010-06-25 2010-06-25
US36078610P 2010-07-01 2010-07-01
US38786210P 2010-09-29 2010-09-29
US201161435710P 2011-01-24 2011-01-24
US201161442115P 2011-02-11 2011-02-11
US201161476210P 2011-04-15 2011-04-15
US201161495268P 2011-06-09 2011-06-09

Publications (1)

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PE20170938A1 true PE20170938A1 (es) 2017-07-13

Family

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Family Applications (8)

Application Number Title Priority Date Filing Date
PE2018000183A PE20180801A1 (es) 2010-06-25 2011-06-25 Composiciones y metodos para suministro al sistema nervioso central de iduronato-2-sulfatasa
PE2012002498A PE20130648A1 (es) 2010-06-25 2011-06-25 Tratamiento del sindrome de sanfilippo tipo b
PE2012002475A PE20130579A1 (es) 2010-06-25 2011-06-25 Composiciones y metodos para suministro al sistema nervioso central de iduronato-2-sulfatasa
PE2012002474A PE20130578A1 (es) 2010-06-25 2011-06-25 Composiciones y metodos para suministro al sistema nervioso central de heparan n-sulfatasa
PE2017001612A PE20180130A1 (es) 2010-06-25 2011-06-25 Composiciones y metodos para suministro al sistema nervioso central de arilsulfatasa a
PE2012002476A PE20130589A1 (es) 2010-06-25 2011-06-25 Composiciones y metodos para suministro al sistema nervioso central de arilsulfatasa a
PE2017000503A PE20170938A1 (es) 2010-06-25 2011-06-25 Suministro al sistema nervioso central de agentes terapeuticos
PE2012002479A PE20130637A1 (es) 2010-06-25 2011-06-25 Suministro al sistema nervioso central de agentes terapeuticos

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Application Number Title Priority Date Filing Date
PE2018000183A PE20180801A1 (es) 2010-06-25 2011-06-25 Composiciones y metodos para suministro al sistema nervioso central de iduronato-2-sulfatasa
PE2012002498A PE20130648A1 (es) 2010-06-25 2011-06-25 Tratamiento del sindrome de sanfilippo tipo b
PE2012002475A PE20130579A1 (es) 2010-06-25 2011-06-25 Composiciones y metodos para suministro al sistema nervioso central de iduronato-2-sulfatasa
PE2012002474A PE20130578A1 (es) 2010-06-25 2011-06-25 Composiciones y metodos para suministro al sistema nervioso central de heparan n-sulfatasa
PE2017001612A PE20180130A1 (es) 2010-06-25 2011-06-25 Composiciones y metodos para suministro al sistema nervioso central de arilsulfatasa a
PE2012002476A PE20130589A1 (es) 2010-06-25 2011-06-25 Composiciones y metodos para suministro al sistema nervioso central de arilsulfatasa a

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