PE20011027A1 - Uso de inhibidores acat para reducir la acumulacion de monocito macrofago y la expresion mmp en las lesiones ateroscleroticas - Google Patents
Uso de inhibidores acat para reducir la acumulacion de monocito macrofago y la expresion mmp en las lesiones ateroscleroticasInfo
- Publication number
- PE20011027A1 PE20011027A1 PE2000001173A PE0011732000A PE20011027A1 PE 20011027 A1 PE20011027 A1 PE 20011027A1 PE 2000001173 A PE2000001173 A PE 2000001173A PE 0011732000 A PE0011732000 A PE 0011732000A PE 20011027 A1 PE20011027 A1 PE 20011027A1
- Authority
- PE
- Peru
- Prior art keywords
- phenyl
- accumulation
- reduce
- macrophagus
- monocyt
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/18—Sulfonamides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Emergency Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16381499P | 1999-11-05 | 1999-11-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE20011027A1 true PE20011027A1 (es) | 2001-10-16 |
Family
ID=22591694
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE2000001173A PE20011027A1 (es) | 1999-11-05 | 2000-11-03 | Uso de inhibidores acat para reducir la acumulacion de monocito macrofago y la expresion mmp en las lesiones ateroscleroticas |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP1229907A1 (fr) |
| JP (1) | JP2003513909A (fr) |
| KR (1) | KR20020050257A (fr) |
| CN (1) | CN1414848A (fr) |
| AR (1) | AR026354A1 (fr) |
| AU (1) | AU1210401A (fr) |
| CA (1) | CA2382676A1 (fr) |
| CO (1) | CO5270017A1 (fr) |
| GT (1) | GT200000193A (fr) |
| HU (1) | HUP0203160A3 (fr) |
| IL (1) | IL149145A0 (fr) |
| PA (1) | PA8506101A1 (fr) |
| PE (1) | PE20011027A1 (fr) |
| PL (1) | PL355148A1 (fr) |
| SV (1) | SV2001000207A (fr) |
| TR (1) | TR200201204T2 (fr) |
| UY (1) | UY26427A1 (fr) |
| WO (1) | WO2001034127A1 (fr) |
| ZA (1) | ZA200201755B (fr) |
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2358734C2 (ru) | 2003-08-29 | 2009-06-20 | Кова Ко., Лтд. | Способ стабилизации бляшки с высоким содержанием липидов и способ профилактики ее разрушения |
| JP2007532617A (ja) * | 2004-04-15 | 2007-11-15 | アテラ バイオテクノロジーズ エービー | アテローム血栓症およびプラーク破壊を予防するためのアネキシンｖ |
| NZ608903A (en) | 2010-11-03 | 2014-06-27 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
| AU2012329045A1 (en) | 2011-10-26 | 2014-04-17 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
| US9708288B2 (en) | 2012-04-27 | 2017-07-18 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
| US9282739B2 (en) | 2012-04-27 | 2016-03-15 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
| US20130291227A1 (en) | 2012-04-27 | 2013-10-31 | Dow Agrosciences Llc | Pesticidal compositions and processes related thereto |
| CA2925873A1 (fr) | 2013-10-17 | 2015-04-23 | Dow Agrosciences Llc | Procedes de preparation de de composes pesticides |
| MX2016004942A (es) | 2013-10-17 | 2016-06-28 | Dow Agrosciences Llc | Procesos para la preparacion de compuestos plaguicidas. |
| US9029554B1 (en) | 2013-10-17 | 2015-05-12 | Dow Agrosciences Llc | Processes for the preparation of pesticidal compounds |
| BR112016007518A2 (pt) | 2013-10-17 | 2017-08-01 | Dow Agrosciences Llc | processos para a preparação de compostos pesticidas |
| JP6487426B2 (ja) | 2013-10-17 | 2019-03-20 | ダウ アグロサイエンシィズ エルエルシー | 有害生物防除化合物の調製法 |
| CN105636442B (zh) | 2013-10-17 | 2018-04-27 | 美国陶氏益农公司 | 制备杀虫化合物的方法 |
| EP3057428A4 (fr) | 2013-10-17 | 2017-05-17 | Dow AgroSciences LLC | Procédés de préparation de composés pesticides |
| CN105792652A (zh) | 2013-10-22 | 2016-07-20 | 美国陶氏益农公司 | 协同杀虫组合物和相关方法 |
| US9295260B2 (en) | 2013-10-22 | 2016-03-29 | Dow Agrosciences Llc | Pesticidal compositions and related methods |
| TW201517797A (zh) | 2013-10-22 | 2015-05-16 | Dow Agrosciences Llc | 協同性殺蟲組成物及相關方法（十一） |
| US9474276B2 (en) | 2013-10-22 | 2016-10-25 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
| US9801383B2 (en) | 2013-10-22 | 2017-10-31 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
| WO2015061140A1 (fr) | 2013-10-22 | 2015-04-30 | Dow Agrosciences Llc | Compositions pesticides synergiques et méthodes associées |
| JP2016535739A (ja) | 2013-10-22 | 2016-11-17 | ダウ アグロサイエンシィズ エルエルシー | 農薬組成物および関連する方法 |
| MX2016005317A (es) | 2013-10-22 | 2016-08-12 | Dow Agrosciences Llc | Composiciones pesticidas y metodos relacionados. |
| RU2016119368A (ru) | 2013-10-22 | 2017-11-28 | ДАУ АГРОСАЙЕНСИЗ ЭлЭлСи | Синергетические пестицидные композиции и связанные с ними способы |
| NZ719754A (en) | 2013-10-22 | 2017-06-30 | Dow Agrosciences Llc | Synergistic pesticidal compositions and related methods |
| AR098096A1 (es) | 2013-10-22 | 2016-05-04 | Dow Agrosciences Llc | Composiciones plaguicidas sinérgicas y métodos relacionados |
| JP2016535024A (ja) | 2013-10-22 | 2016-11-10 | ダウ アグロサイエンシィズ エルエルシー | 相乗的有害生物防除組成物および関連する方法 |
| NZ719688A (en) | 2013-10-22 | 2017-06-30 | Dow Agrosciences Llc | Pesticidal compositions and related methods |
| KR20160074582A (ko) | 2013-10-22 | 2016-06-28 | 다우 아그로사이언시즈 엘엘씨 | 상승작용적 살충 조성물 및 관련 방법 |
| WO2015061163A1 (fr) | 2013-10-22 | 2015-04-30 | Dow Agrosciences Llc | Compositions pesticides et procédés associés |
| JP2016538266A (ja) | 2013-10-22 | 2016-12-08 | ダウ アグロサイエンシィズ エルエルシー | 相乗的有害生物防除組成物および関連する方法 |
| MX2016005323A (es) | 2013-10-22 | 2016-08-12 | Dow Agrosciences Llc | Composiciones pesticidas y metodos relacionados. |
| KR20170038785A (ko) | 2014-07-31 | 2017-04-07 | 다우 아그로사이언시즈 엘엘씨 | 3-(3-클로로-1h-피라졸-1-일)피리딘의 제조 방법 |
| BR112017000565A2 (pt) | 2014-07-31 | 2017-11-07 | Dow Agrosciences Llc | processo para a preparação de 3-(3-cloro-1h-pirazol-1-il)piridina |
| JP2017523168A (ja) | 2014-07-31 | 2017-08-17 | ダウ アグロサイエンシィズ エルエルシー | ３−（３−クロロ−１ｈ−ピラゾール−１−イル）ピリジンの製造方法 |
| WO2016028328A1 (fr) | 2014-08-19 | 2016-02-25 | Dow Agrosciences Llc | Procédé de préparation de 3-(3-chloro-1h-pyrazol-1-yl)pyridine |
| US9085552B1 (en) | 2014-09-12 | 2015-07-21 | Dow Agrosciences Llc | Process for the preparation of 3-(3-chloro-1H-pyrazol-1-yl)pyridine |
| EP3209671B8 (fr) * | 2014-10-21 | 2019-07-31 | Council of Scientific and Industrial Research | Esters de phosphonate d'alkylidène en tant qu'inducteurs de p-glycoprotéine |
| PE20190656A1 (es) * | 2016-07-29 | 2019-05-08 | Lupin Ltd | Compuestos de tiazolo-piridina sustituida como inhibidores de malt1 |
| WO2018093966A1 (fr) | 2016-11-16 | 2018-05-24 | Purdue Research Foundation | Compositions et procédés de régulation du poids corporel et des syndromes métaboliques |
| US10233155B2 (en) | 2016-12-29 | 2019-03-19 | Dow Agrosciences Llc | Processes for the preparation of pesticide compounds |
| CN110139853B (zh) | 2016-12-29 | 2023-06-16 | 美国陶氏益农公司 | 用于制备杀有害生物化合物的方法 |
| AU2018354777A1 (en) | 2017-10-27 | 2020-04-16 | Bayer Aktiengesellschaft | Novel Pyrazolo-pyrrolo-pyrimidine-dione derivatives as P2X3 inhibitors |
| WO2020113094A1 (fr) | 2018-11-30 | 2020-06-04 | Nuvation Bio Inc. | Composés pyrrole et pyrazole et leurs procédés d'utilisation |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU654688B2 (en) * | 1990-10-30 | 1994-11-17 | Warner-Lambert Company | Oxysulfonyl carbamates |
| IL109431A (en) * | 1993-05-14 | 2001-01-11 | Warner Lambert Co | Pharmaceutical compositions containing n-acyl sulfamic acid esters (or thioesters), n-acyl sulfonamides, and n-sulfonyl carbamic acid esters (or thioesters), for regulating plasma cholesterol concentration, and certain such novel compounds |
| IT1270976B (it) * | 1993-08-06 | 1997-05-26 | Pierrel Spa | Composti inibitpri di acil enzima-a-colesterolo-o-acil transferasi ad attivita' terapeutica, loro uso e composizioni farmaceutiche che li contengono |
| JPH11510184A (ja) * | 1995-08-04 | 1999-09-07 | ワーナー−ランバート・コンパニー | リポ蛋白レベルを低下させるための医薬の製造用スルファミン酸誘導体、アシルスルホンアミドまたはスルホニルカルバメートの使用 |
| CN1217656C (zh) * | 1995-11-02 | 2005-09-07 | 沃尼尔·朗伯公司 | 用于调节脂浓度的方法和药物组合物 |
| IL140982A0 (en) * | 1998-07-21 | 2002-02-10 | Warner Lambert Co | Coadministration of acat and mmp inhibitors for the treatment of atherosclerotic lesions |
-
2000
- 2000-10-17 CN CN00812939A patent/CN1414848A/zh active Pending
- 2000-10-17 TR TR2002/01204T patent/TR200201204T2/xx unknown
- 2000-10-17 HU HU0203160A patent/HUP0203160A3/hu unknown
- 2000-10-17 PL PL00355148A patent/PL355148A1/xx not_active Application Discontinuation
- 2000-10-17 EP EP00973608A patent/EP1229907A1/fr not_active Withdrawn
- 2000-10-17 IL IL14914500A patent/IL149145A0/xx unknown
- 2000-10-17 KR KR1020027005801A patent/KR20020050257A/ko not_active Application Discontinuation
- 2000-10-17 CA CA002382676A patent/CA2382676A1/fr not_active Abandoned
- 2000-10-17 JP JP2001536127A patent/JP2003513909A/ja active Pending
- 2000-10-17 AU AU12104/01A patent/AU1210401A/en not_active Abandoned
- 2000-10-17 WO PCT/US2000/028705 patent/WO2001034127A1/fr not_active Application Discontinuation
- 2000-10-25 SV SV2000000207A patent/SV2001000207A/es unknown
- 2000-11-01 PA PA20008506101A patent/PA8506101A1/es unknown
- 2000-11-03 PE PE2000001173A patent/PE20011027A1/es not_active Application Discontinuation
- 2000-11-03 UY UY26427A patent/UY26427A1/es not_active Application Discontinuation
- 2000-11-03 AR ARP000105803A patent/AR026354A1/es unknown
- 2000-11-03 CO CO00083934A patent/CO5270017A1/es not_active Application Discontinuation
- 2000-11-03 GT GT200000193A patent/GT200000193A/es unknown
-
2002
- 2002-03-01 ZA ZA200201755A patent/ZA200201755B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20020050257A (ko) | 2002-06-26 |
| PA8506101A1 (es) | 2002-10-28 |
| ZA200201755B (en) | 2003-08-27 |
| PL355148A1 (en) | 2004-04-05 |
| GT200000193A (es) | 2002-04-27 |
| WO2001034127A1 (fr) | 2001-05-17 |
| AR026354A1 (es) | 2003-02-05 |
| CO5270017A1 (es) | 2003-04-30 |
| HUP0203160A2 (hu) | 2003-01-28 |
| AU1210401A (en) | 2001-06-06 |
| IL149145A0 (en) | 2002-11-10 |
| HUP0203160A3 (en) | 2006-02-28 |
| CA2382676A1 (fr) | 2001-05-17 |
| SV2001000207A (es) | 2001-10-16 |
| CN1414848A (zh) | 2003-04-30 |
| UY26427A1 (es) | 2000-12-29 |
| TR200201204T2 (tr) | 2002-08-21 |
| JP2003513909A (ja) | 2003-04-15 |
| EP1229907A1 (fr) | 2002-08-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC | Refusal |