IT1270976B - Composti inibitpri di acil enzima-a-colesterolo-o-acil transferasi ad attivita' terapeutica, loro uso e composizioni farmaceutiche che li contengono - Google Patents
Composti inibitpri di acil enzima-a-colesterolo-o-acil transferasi ad attivita' terapeutica, loro uso e composizioni farmaceutiche che li contengonoInfo
- Publication number
- IT1270976B IT1270976B ITMI931806A ITMI931806A IT1270976B IT 1270976 B IT1270976 B IT 1270976B IT MI931806 A ITMI931806 A IT MI931806A IT MI931806 A ITMI931806 A IT MI931806A IT 1270976 B IT1270976 B IT 1270976B
- Authority
- IT
- Italy
- Prior art keywords
- acyl
- cholesterol
- contain
- pharmaceutical compositions
- therapeutic activities
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI931806A IT1270976B (it) | 1993-08-06 | 1993-08-06 | Composti inibitpri di acil enzima-a-colesterolo-o-acil transferasi ad attivita' terapeutica, loro uso e composizioni farmaceutiche che li contengono |
JP6204436A JPH07149733A (ja) | 1993-08-06 | 1994-08-05 | 治療活性を有するアシル酵素−a−コレステロール−o−アシル−トランスフエラーゼの阻害剤化合物、その利用及びそれを含む製薬学的組成物 |
GB9415873A GB2280675A (en) | 1993-08-06 | 1994-08-05 | ACAT-inhibiting imidazoles |
DE4428025A DE4428025A1 (de) | 1993-08-06 | 1994-08-08 | Inhibitoren der Acyl-Enzym-A-Cholesterin-O-Acyl-Transferase mit therapeutischer Wirksamkeit, ihre Verwendung und sie enthaltende pharmazeutische Zusammensetzungen |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI931806A IT1270976B (it) | 1993-08-06 | 1993-08-06 | Composti inibitpri di acil enzima-a-colesterolo-o-acil transferasi ad attivita' terapeutica, loro uso e composizioni farmaceutiche che li contengono |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI931806A0 ITMI931806A0 (it) | 1993-08-06 |
ITMI931806A1 ITMI931806A1 (it) | 1995-02-06 |
IT1270976B true IT1270976B (it) | 1997-05-26 |
Family
ID=11366803
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI931806A IT1270976B (it) | 1993-08-06 | 1993-08-06 | Composti inibitpri di acil enzima-a-colesterolo-o-acil transferasi ad attivita' terapeutica, loro uso e composizioni farmaceutiche che li contengono |
Country Status (4)
Country | Link |
---|---|
JP (1) | JPH07149733A (it) |
DE (1) | DE4428025A1 (it) |
GB (1) | GB2280675A (it) |
IT (1) | IT1270976B (it) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1414848A (zh) * | 1999-11-05 | 2003-04-30 | 沃尼尔·朗伯公司 | Acat抑制剂对斑块破裂的预防 |
RU2358734C2 (ru) * | 2003-08-29 | 2009-06-20 | Кова Ко., Лтд. | Способ стабилизации бляшки с высоким содержанием липидов и способ профилактики ее разрушения |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1248528B (it) * | 1991-06-21 | 1995-01-19 | Pierrel Spa | Derivati di eteri e tioeteri (etero) aromatici aventi attivita` antiiperlipidemica, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono. |
-
1993
- 1993-08-06 IT ITMI931806A patent/IT1270976B/it active IP Right Grant
-
1994
- 1994-08-05 JP JP6204436A patent/JPH07149733A/ja active Pending
- 1994-08-05 GB GB9415873A patent/GB2280675A/en not_active Withdrawn
- 1994-08-08 DE DE4428025A patent/DE4428025A1/de not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
ITMI931806A0 (it) | 1993-08-06 |
GB2280675A (en) | 1995-02-08 |
DE4428025A1 (de) | 1995-02-09 |
JPH07149733A (ja) | 1995-06-13 |
GB9415873D0 (en) | 1994-09-28 |
ITMI931806A1 (it) | 1995-02-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19960830 |