PE20010982A1 - Composicion estable para dosis oral de liberacion extendida - Google Patents
Composicion estable para dosis oral de liberacion extendidaInfo
- Publication number
- PE20010982A1 PE20010982A1 PE2000001371A PE0013712000A PE20010982A1 PE 20010982 A1 PE20010982 A1 PE 20010982A1 PE 2000001371 A PE2000001371 A PE 2000001371A PE 0013712000 A PE0013712000 A PE 0013712000A PE 20010982 A1 PE20010982 A1 PE 20010982A1
- Authority
- PE
- Peru
- Prior art keywords
- nucleum
- hours
- film
- plasma
- water
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/14—Decongestants or antiallergics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Toxicology (AREA)
- Otolaryngology (AREA)
- Immunology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Toys (AREA)
- Cosmetics (AREA)
Abstract
SE REFIERE A UNA COMPOSICION DE DOSIS ORAL SOLIDA DE LIBERACION EXTENDIDA REVESTIDA CON UNA PELICULA QUE COMPRENDE a)NUCLEO MATRIZ QUE COMPRENDE 1)DESCONGESTIVO COMO PSEUDOEFEDRINA PARA PRODUCIR UNA CONCENTRACION EN PLASMA MAXIMO GEOMETRICA DE 345 ng/ml A 365 ng/ml DE 7,60 HORAS A 8,40 HORAS; 2)MATRIZ POLIMERICA; 3)SAL BASICA INSOLUBLE EN AGUA (CALCIO, MAGNESIO, ALUMINIO), 4)AGLUTINANTE; 5)LUBRICANTE; 6)DESLIZANTE; b)UN SEGUNDO REVESTIMIENTO DE PELICULA QUE COMPRENDE: 1)DESLORATADINA PARA PRODUCIR UNA CONCENTRACION EN PLASMA MAXIMO GEOMETRICA DE 2,10ng/ml A 2,45ng/ml DE 4 HORAS A 4,5 HORAS Y PRODUCIR UNA CONCENTRACION EN PLASMA MAXIMO GEOMETRICA DE 3-HIDROXIDESLORATADINA DE 0,75 ng/ml EN 5,50 HORAS; 2)ESTER COPOLIMERICO NEUTRO O CATIONICO FORMADOR DE PELICULA QUE SE DILATA EN AGUA; 3)LUBRICANTE; 4)MODIFICADOR DE PELICULA SOLUBLE EN AGUA; 5)AGENTE ANTIESPUMA; c)PRIMER REVESTIMIENTO ENTRE EL REVESTIMIENTO DE PELICULA Y EL NUCLEO QUE PROVEE LA LIBERACION DE DESLORATADINA DESDE EL SEGUNDO REVESTIMIENTO DE PELICULA Y UNA LIBERACION EXTENDIDA DEL DESCONGESTIVO NASAL DESDE EL NUCLEO QUE COMPRENDE 1)ESTER COPOLIMERICO NEUTRO O CATIONICO FORMADOR DE PELICULA QUE SE DILATA EN AGUA; 2)LUBRICANTE; 3)MODIFICADOR DE PELICULA SOLUBLE EN AGUA; 4)AGENTE ANTIESPUMA; LA COMPOSICION SE CARACTERIZA POR CONTENER MENOS DE 2% DE PRODUCTOS DE DESCOMPOSICION DE DESLORATADINA COMO N-FORMILDESLORATADINA
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17283699P | 1999-12-20 | 1999-12-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20010982A1 true PE20010982A1 (es) | 2001-09-28 |
Family
ID=22629437
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2000001371A PE20010982A1 (es) | 1999-12-20 | 2000-12-20 | Composicion estable para dosis oral de liberacion extendida |
Country Status (38)
Country | Link |
---|---|
US (2) | US6979463B2 (es) |
EP (2) | EP1112738B1 (es) |
JP (3) | JP5042403B2 (es) |
KR (2) | KR100936572B1 (es) |
CN (3) | CN101081224B (es) |
AR (1) | AR027033A1 (es) |
AT (1) | ATE463240T1 (es) |
AU (4) | AU2277101A (es) |
BR (1) | BR0006403A (es) |
CA (1) | CA2329217C (es) |
CO (1) | CO5251435A1 (es) |
CY (1) | CY1110693T1 (es) |
CZ (1) | CZ302860B6 (es) |
DE (1) | DE60044117D1 (es) |
DK (1) | DK1112738T3 (es) |
EC (1) | ECSP003836A (es) |
EG (1) | EG23759A (es) |
ES (1) | ES2341751T3 (es) |
HK (1) | HK1034453A1 (es) |
HU (1) | HUP0004988A3 (es) |
ID (1) | ID28675A (es) |
IL (1) | IL140450A (es) |
MX (1) | MXPA00013037A (es) |
MY (1) | MY130773A (es) |
NO (1) | NO331645B1 (es) |
NZ (1) | NZ509028A (es) |
PE (1) | PE20010982A1 (es) |
PL (1) | PL211573B1 (es) |
PT (1) | PT1112738E (es) |
RU (2) | RU2303440C2 (es) |
SA (2) | SA06270069B1 (es) |
SG (1) | SG109438A1 (es) |
SI (1) | SI1112738T1 (es) |
SK (1) | SK287684B6 (es) |
TR (1) | TR200003787A3 (es) |
TW (1) | TWI225414B (es) |
WO (1) | WO2001045668A2 (es) |
ZA (1) | ZA200007715B (es) |
Families Citing this family (38)
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WO2001045676A2 (en) | 1999-12-20 | 2001-06-28 | Schering Corporation | Extended release oral dosage composition |
SK287684B6 (sk) | 1999-12-20 | 2011-06-06 | Schering Corporation | Pevná orálna farmaceutická dávková forma s predĺženým uvoľňovaním |
US7405223B2 (en) | 2000-02-03 | 2008-07-29 | Schering Corporation | Treating allergic and inflammatory conditions |
US20030070584A1 (en) | 2001-05-15 | 2003-04-17 | Cynthia Gulian | Dip coating compositions containing cellulose ethers |
BR0210534A (pt) * | 2001-06-20 | 2004-06-22 | Schering Corp | Anti-histaminas para o tratamento de congestão nasal e obstrução nasal |
US8309118B2 (en) | 2001-09-28 | 2012-11-13 | Mcneil-Ppc, Inc. | Film forming compositions containing sucralose |
NZ535455A (en) * | 2002-02-21 | 2009-08-28 | Biovail Lab Int Srl | Controlled release dosage forms |
US8323692B2 (en) | 2002-02-21 | 2012-12-04 | Valeant International Bermuda | Controlled release dosage forms |
PT1507531E (pt) * | 2003-03-12 | 2007-03-30 | Teva Pharma | Composições farmacêuticas estáveis de desloratadina |
US20050013863A1 (en) | 2003-07-18 | 2005-01-20 | Depomed, Inc., A Corporation Of The State Of California | Dual drug dosage forms with improved separation of drugs |
JP4999329B2 (ja) * | 2003-12-01 | 2012-08-15 | 武田薬品工業株式会社 | 固形製剤の印刷前処理方法 |
CA2585122A1 (en) * | 2004-10-25 | 2006-05-04 | Schering Corporation | M1 and/or m3 receptor antagonists in combination with other actives for treating respiratory disorders |
US20060252830A1 (en) * | 2005-05-06 | 2006-11-09 | Brandon Stephen F | Method for the treatment of magnesium and potassium deficiencies |
US20060252831A1 (en) * | 2005-05-06 | 2006-11-09 | Christopher Offen | Method for the treatment of magnesium and potassium deficiencies |
US20070014855A1 (en) * | 2005-07-12 | 2007-01-18 | Rahul Gawande S | Stable desloratadine compositions |
US20070036859A1 (en) * | 2005-08-11 | 2007-02-15 | Perry Ronald L | Sustained release antihistamine and decongestant composition |
US7827042B2 (en) | 2005-11-30 | 2010-11-02 | The Invention Science Fund I, Inc | Methods and systems related to transmission of nutraceutical associated information |
US7927787B2 (en) | 2006-06-28 | 2011-04-19 | The Invention Science Fund I, Llc | Methods and systems for analysis of nutraceutical associated components |
US10296720B2 (en) | 2005-11-30 | 2019-05-21 | Gearbox Llc | Computational systems and methods related to nutraceuticals |
US8297028B2 (en) | 2006-06-14 | 2012-10-30 | The Invention Science Fund I, Llc | Individualized pharmaceutical selection and packaging |
US8000981B2 (en) | 2005-11-30 | 2011-08-16 | The Invention Science Fund I, Llc | Methods and systems related to receiving nutraceutical associated information |
US8068991B2 (en) | 2005-11-30 | 2011-11-29 | The Invention Science Fund I, Llc | Systems and methods for transmitting pathogen related information and responding |
US7974856B2 (en) | 2005-11-30 | 2011-07-05 | The Invention Science Fund I, Llc | Computational systems and methods related to nutraceuticals |
US8340944B2 (en) | 2005-11-30 | 2012-12-25 | The Invention Science Fund I, Llc | Computational and/or control systems and methods related to nutraceutical agent selection and dosing |
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AR061166A1 (es) * | 2006-06-01 | 2008-08-06 | Schering Corp | Composiciones farmaceuticas para la liberacion sostenida de fenilferina |
PL2034970T3 (pl) * | 2006-06-01 | 2012-12-31 | Msd Consumer Care Inc | Preparat farmaceutyczny o przedłużonym uwalnianiu zawierający fenylefrynę |
NZ573174A (en) * | 2006-06-01 | 2012-01-12 | Msd Consumer Care Inc | Sustained release pharmaceutical dosage form containing phenylephrine |
RU2008151945A (ru) * | 2006-06-01 | 2010-07-20 | Шеринг Корпорейшн (US) | Лекарственные формы с пульсирующим высвобождением и фармацевтические композиции фенилэфрина |
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-
2000
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- 2000-12-19 AU AU22771/01A patent/AU2277101A/en not_active Abandoned
- 2000-12-19 WO PCT/US2000/034412 patent/WO2001045668A2/en active Application Filing
- 2000-12-20 SI SI200031059T patent/SI1112738T1/sl unknown
- 2000-12-20 CN CN2006100944812A patent/CN101081224B/zh not_active Expired - Fee Related
- 2000-12-20 CN CNB001373005A patent/CN1211079C/zh not_active Expired - Fee Related
- 2000-12-20 ES ES00311445T patent/ES2341751T3/es not_active Expired - Lifetime
- 2000-12-20 KR KR1020000079045A patent/KR100936572B1/ko not_active IP Right Cessation
- 2000-12-20 PE PE2000001371A patent/PE20010982A1/es not_active Application Discontinuation
- 2000-12-20 MX MXPA00013037A patent/MXPA00013037A/es active IP Right Grant
- 2000-12-20 MY MYPI20005989A patent/MY130773A/en unknown
- 2000-12-20 NO NO20006504A patent/NO331645B1/no not_active IP Right Cessation
- 2000-12-20 CN CNA2005100713014A patent/CN1679569A/zh active Pending
- 2000-12-20 DK DK00311445.1T patent/DK1112738T3/da active
- 2000-12-20 PL PL344715A patent/PL211573B1/pl not_active IP Right Cessation
- 2000-12-20 EG EG20001571A patent/EG23759A/xx active
- 2000-12-20 JP JP2000387828A patent/JP5042403B2/ja not_active Expired - Fee Related
- 2000-12-20 CO CO00096727A patent/CO5251435A1/es active IP Right Grant
- 2000-12-20 CA CA002329217A patent/CA2329217C/en not_active Expired - Fee Related
- 2000-12-20 AR ARP000106790A patent/AR027033A1/es not_active Application Discontinuation
- 2000-12-20 TW TW089127375A patent/TWI225414B/zh not_active IP Right Cessation
- 2000-12-20 EC EC2000003836A patent/ECSP003836A/es unknown
- 2000-12-20 NZ NZ509028A patent/NZ509028A/xx not_active IP Right Cessation
- 2000-12-20 AU AU72443/00A patent/AU781924B2/en not_active Ceased
- 2000-12-20 DE DE60044117T patent/DE60044117D1/de not_active Expired - Lifetime
- 2000-12-20 HU HU0004988A patent/HUP0004988A3/hu unknown
- 2000-12-20 EP EP00311445A patent/EP1112738B1/en not_active Expired - Lifetime
- 2000-12-20 SG SG200007531A patent/SG109438A1/en unknown
- 2000-12-20 IL IL140450A patent/IL140450A/en not_active IP Right Cessation
- 2000-12-20 AT AT00311445T patent/ATE463240T1/de active
- 2000-12-20 CZ CZ20004812A patent/CZ302860B6/cs not_active IP Right Cessation
- 2000-12-20 PT PT00311445T patent/PT1112738E/pt unknown
- 2000-12-20 BR BR0006403-3A patent/BR0006403A/pt not_active Application Discontinuation
- 2000-12-20 RU RU2000131898/15A patent/RU2303440C2/ru not_active IP Right Cessation
- 2000-12-20 TR TR2000/03787A patent/TR200003787A3/tr unknown
- 2000-12-20 ID IDP20001115A patent/ID28675A/id unknown
- 2000-12-20 EP EP10159005A patent/EP2196195A3/en not_active Withdrawn
- 2000-12-20 ZA ZA200007715A patent/ZA200007715B/xx unknown
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2001
- 2001-02-25 SA SA06270069A patent/SA06270069B1/ar unknown
- 2001-02-25 SA SA01210741A patent/SA01210741B1/ar unknown
- 2001-07-19 HK HK01105066.7A patent/HK1034453A1/xx not_active IP Right Cessation
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2002
- 2002-06-19 US US10/175,460 patent/US6979463B2/en not_active Expired - Lifetime
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2005
- 2005-08-22 AU AU2005203771A patent/AU2005203771A1/en not_active Abandoned
- 2005-10-06 US US11/244,743 patent/US7820199B2/en not_active Expired - Fee Related
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2007
- 2007-02-02 RU RU2007104095/15A patent/RU2423106C9/ru not_active IP Right Cessation
- 2007-12-14 JP JP2007324054A patent/JP2008081510A/ja active Pending
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2009
- 2009-02-06 AU AU2009200460A patent/AU2009200460B2/en not_active Ceased
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2010
- 2010-06-07 CY CY20101100503T patent/CY1110693T1/el unknown
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2011
- 2011-02-23 KR KR1020110016213A patent/KR101234940B1/ko not_active IP Right Cessation
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2012
- 2012-08-17 JP JP2012181028A patent/JP2012224642A/ja not_active Withdrawn
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