PE20000346A1 - Administracion de un agente activo en aerosol - Google Patents
Administracion de un agente activo en aerosolInfo
- Publication number
- PE20000346A1 PE20000346A1 PE1999000202A PE00020299A PE20000346A1 PE 20000346 A1 PE20000346 A1 PE 20000346A1 PE 1999000202 A PE1999000202 A PE 1999000202A PE 00020299 A PE00020299 A PE 00020299A PE 20000346 A1 PE20000346 A1 PE 20000346A1
- Authority
- PE
- Peru
- Prior art keywords
- hormone
- bormeron
- active agent
- refers
- interferon
- Prior art date
Links
- 239000013543 active substance Substances 0.000 title abstract 3
- 239000000443 aerosol Substances 0.000 title abstract 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
- 102100022712 Alpha-1-antitrypsin Human genes 0.000 abstract 1
- VOVIALXJUBGFJZ-KWVAZRHASA-N Budesonide Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@@H]2[C@@H]1[C@@H]1C[C@H]3OC(CCC)O[C@@]3(C(=O)CO)[C@@]1(C)C[C@@H]2O VOVIALXJUBGFJZ-KWVAZRHASA-N 0.000 abstract 1
- 102000055006 Calcitonin Human genes 0.000 abstract 1
- 108060001064 Calcitonin Proteins 0.000 abstract 1
- PMATZTZNYRCHOR-CGLBZJNRSA-N Cyclosporin A Chemical compound CC[C@@H]1NC(=O)[C@H]([C@H](O)[C@H](C)C\C=C\C)N(C)C(=O)[C@H](C(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](CC(C)C)N(C)C(=O)[C@@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](CC(C)C)N(C)C(=O)CN(C)C1=O PMATZTZNYRCHOR-CGLBZJNRSA-N 0.000 abstract 1
- 229930105110 Cyclosporin A Natural products 0.000 abstract 1
- 108010036949 Cyclosporine Proteins 0.000 abstract 1
- 102000038461 Growth Hormone-Releasing Hormone Human genes 0.000 abstract 1
- 239000000095 Growth Hormone-Releasing Hormone Substances 0.000 abstract 1
- 102000002265 Human Growth Hormone Human genes 0.000 abstract 1
- 108010000521 Human Growth Hormone Proteins 0.000 abstract 1
- 239000000854 Human Growth Hormone Substances 0.000 abstract 1
- 102000004877 Insulin Human genes 0.000 abstract 1
- 108090001061 Insulin Proteins 0.000 abstract 1
- 102000006992 Interferon-alpha Human genes 0.000 abstract 1
- 108010047761 Interferon-alpha Proteins 0.000 abstract 1
- 102000014150 Interferons Human genes 0.000 abstract 1
- 108010050904 Interferons Proteins 0.000 abstract 1
- 102000009151 Luteinizing Hormone Human genes 0.000 abstract 1
- 108010073521 Luteinizing Hormone Proteins 0.000 abstract 1
- 102000003982 Parathyroid hormone Human genes 0.000 abstract 1
- 108090000445 Parathyroid hormone Proteins 0.000 abstract 1
- 101710142969 Somatoliberin Proteins 0.000 abstract 1
- 102000005157 Somatostatin Human genes 0.000 abstract 1
- 108010056088 Somatostatin Proteins 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 108010050122 alpha 1-Antitrypsin Proteins 0.000 abstract 1
- 229940024142 alpha 1-antitrypsin Drugs 0.000 abstract 1
- 229960004436 budesonide Drugs 0.000 abstract 1
- 229960004015 calcitonin Drugs 0.000 abstract 1
- BBBFJLBPOGFECG-VJVYQDLKSA-N calcitonin Chemical compound N([C@H](C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC=1C=CC(O)=CC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N1[C@@H](CCC1)C(N)=O)C(C)C)C(=O)[C@@H]1CSSC[C@H](N)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)O)C(=O)N1 BBBFJLBPOGFECG-VJVYQDLKSA-N 0.000 abstract 1
- 229960001265 ciclosporin Drugs 0.000 abstract 1
- 229930182912 cyclosporin Natural products 0.000 abstract 1
- 229960004222 factor ix Drugs 0.000 abstract 1
- 229960000301 factor viii Drugs 0.000 abstract 1
- 230000003325 follicular Effects 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 230000003434 inspiratory effect Effects 0.000 abstract 1
- 229940125396 insulin Drugs 0.000 abstract 1
- 229940079322 interferon Drugs 0.000 abstract 1
- 239000003055 low molecular weight heparin Substances 0.000 abstract 1
- 229940127215 low-molecular weight heparin Drugs 0.000 abstract 1
- 229940040129 luteinizing hormone Drugs 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000000199 parathyroid hormone Substances 0.000 abstract 1
- 229960001319 parathyroid hormone Drugs 0.000 abstract 1
- 230000000241 respiratory effect Effects 0.000 abstract 1
- NHXLMOGPVYXJNR-ATOGVRKGSA-N somatostatin Chemical compound C([C@H]1C(=O)N[C@H](C(N[C@@H](CO)C(=O)N[C@@H](CSSC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C=CC=CC=2)C(=O)N[C@@H](CC=2C3=CC=CC=C3NC=2)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(=O)N1)[C@@H](C)O)NC(=O)CNC(=O)[C@H](C)N)C(O)=O)=O)[C@H](O)C)C1=CC=CC=C1 NHXLMOGPVYXJNR-ATOGVRKGSA-N 0.000 abstract 1
- 229960000553 somatostatin Drugs 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0001—Details of inhalators; Constructional features thereof
- A61M15/002—Details of inhalators; Constructional features thereof with air flow regulating means
Abstract
SE REFIERE A UNA COMPOSICION EN AEROSOL CON UN INDICE DE FLUJO INSPIRATORIO INFERIOR A 17 LITROS POR MINUTO QUE COMPRENDE UN AGENTE ACTIVO EN FORMA DE POLVO SECO, NEBULIZACION, SOLUCION, SUSPENSION, QUE OPCIONALMENTE ESTA MEZCLADO CON UN IMPELENTE. EL AGENTE ACTIVO PUEDE SER CICLOSPORINA, HORMONA PARATIROIDEA, HORMONA FOLICULO ESTIMULANTE, ANTITRIPSINA ALFA-1, BUDESONIDA, HORMONA DEL CRECIMIENTO HUMANO, HORMONA LIBERADORA DE LA HORMONA DEL CRECIMIENTO, INTERFERON ALFA, INTERFERON BETA, FACTOR ESTIMULANTE DE COLONIAS DEL CRECIMIENTO, HORMONA LIBERADORA DE LA HORMONA LUTEINIZANTE, CALCITONINA, HEPARINA DE BAJO PESO MOLECULAR, SOMATOSTATINA, ANTICUERPO DEL VIRUS SINCITIAL RESPIRATORIO, ERITROPOYETINA, FACTOR VIII, FACTOR IX, CEREDASA, CEREZIMA, INSULINA. TAMBIEN SE REFIERE A UN DISPOSITIVO QUE PRESENTA UN REGULADOR DE FLUJO CON ABERTURAS DE 0,5 mm A 0,9 mm DE DIAMETRO EN EL CUAL EL REGULADOR DE FLUJO CONSISTE EN UNA VALVULA
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7821498P | 1998-03-16 | 1998-03-16 | |
US7821298P | 1998-03-16 | 1998-03-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20000346A1 true PE20000346A1 (es) | 2000-04-12 |
Family
ID=26760240
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE1999000202A PE20000346A1 (es) | 1998-03-16 | 1999-03-15 | Administracion de un agente activo en aerosol |
Country Status (42)
Country | Link |
---|---|
US (2) | US6655379B2 (es) |
EP (1) | EP1066074A1 (es) |
JP (1) | JP4195191B2 (es) |
KR (1) | KR100620338B1 (es) |
CN (1) | CN1292714B (es) |
AP (1) | AP1342A (es) |
AR (1) | AR018161A1 (es) |
AU (1) | AU750539B2 (es) |
BG (1) | BG65091B1 (es) |
BR (1) | BR9908771A (es) |
CA (1) | CA2322045C (es) |
CO (1) | CO5060522A1 (es) |
DZ (1) | DZ2744A1 (es) |
EA (1) | EA003196B1 (es) |
EE (1) | EE200000546A (es) |
GE (1) | GEP20043260B (es) |
HN (1) | HN1999000028A (es) |
HR (2) | HRP990081A2 (es) |
HU (1) | HUP0100848A3 (es) |
ID (1) | ID26237A (es) |
IL (1) | IL138153A0 (es) |
IS (1) | IS5595A (es) |
LT (1) | LT4818B (es) |
LV (1) | LV12586B (es) |
MA (1) | MA26033A1 (es) |
MY (1) | MY131803A (es) |
NO (1) | NO20004627L (es) |
NZ (1) | NZ506289A (es) |
OA (1) | OA11529A (es) |
PA (1) | PA8468901A1 (es) |
PE (1) | PE20000346A1 (es) |
PL (1) | PL343276A1 (es) |
RO (1) | RO121834B1 (es) |
SA (1) | SA99200198B1 (es) |
SI (1) | SI20413A (es) |
SK (1) | SK13632000A3 (es) |
TN (1) | TNSN99038A1 (es) |
TR (1) | TR200002692T2 (es) |
TW (1) | TWI228998B (es) |
UY (1) | UY25432A1 (es) |
WO (1) | WO1999047196A1 (es) |
YU (1) | YU56600A (es) |
Families Citing this family (127)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6290991B1 (en) | 1994-12-02 | 2001-09-18 | Quandrant Holdings Cambridge Limited | Solid dose delivery vehicle and methods of making same |
US6309671B1 (en) * | 1995-04-14 | 2001-10-30 | Inhale Therapeutic Systems | Stable glassy state powder formulations |
US20060165606A1 (en) | 1997-09-29 | 2006-07-27 | Nektar Therapeutics | Pulmonary delivery particles comprising water insoluble or crystalline active agents |
US6565885B1 (en) | 1997-09-29 | 2003-05-20 | Inhale Therapeutic Systems, Inc. | Methods of spray drying pharmaceutical compositions |
GB9807232D0 (en) * | 1998-04-03 | 1998-06-03 | Univ Cardiff | Aerosol composition |
UA73924C2 (en) * | 1998-10-09 | 2005-10-17 | Nektar Therapeutics | Device for delivering active agent formulation to lungs of human patient |
GB2353222B (en) * | 1999-06-23 | 2001-09-19 | Cambridge Consultants | Inhalers |
US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
US6606992B1 (en) | 1999-06-30 | 2003-08-19 | Nektar Therapeutics | Systems and methods for aerosolizing pharmaceutical formulations |
US7305986B1 (en) | 1999-07-23 | 2007-12-11 | Mannkind Corporation | Unit dose capsules for use in a dry powder inhaler |
US7464706B2 (en) | 1999-07-23 | 2008-12-16 | Mannkind Corporation | Unit dose cartridge and dry powder inhaler |
JP4711520B2 (ja) * | 2000-03-21 | 2011-06-29 | 日本ケミカルリサーチ株式会社 | 生理活性ペプチド含有粉末 |
PE20011227A1 (es) * | 2000-04-17 | 2002-01-07 | Chiesi Farma Spa | Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros |
MXPA02001323A (es) | 2000-05-10 | 2004-07-16 | Alliance Pharma | Microgranulos con base fosfolipida para la liberacion de farmaco. |
US7871598B1 (en) | 2000-05-10 | 2011-01-18 | Novartis Ag | Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use |
US8404217B2 (en) | 2000-05-10 | 2013-03-26 | Novartis Ag | Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use |
US7744855B2 (en) | 2000-06-27 | 2010-06-29 | Vectura Limited | Method of making particles for use in a pharmaceutical composition |
US6339107B1 (en) | 2000-08-02 | 2002-01-15 | Syntex (U.S.A.) Llc | Methods for treatment of Emphysema using 13-cis retinoic acid |
EP1935869A1 (en) | 2000-10-02 | 2008-06-25 | F. Hoffmann-La Roche Ag | Retinoids for the treatment of emphysema |
US7049283B2 (en) | 2000-12-06 | 2006-05-23 | Novartis Ag | Pharmaceutical compositions for the oral delivery of pharmacologically active agents |
US6782887B2 (en) * | 2001-01-12 | 2004-08-31 | Becton, Dickinson And Company | Medicament respiratory delivery device and cartridge |
ES2431634T3 (es) | 2001-06-20 | 2013-11-27 | Novartis Ag | Dispositivo de administración de aerosol |
GB2380946A (en) * | 2001-08-31 | 2003-04-23 | Medic Aid Ltd | Nebuliser arrangement |
ATE508735T1 (de) | 2001-12-19 | 2011-05-15 | Novartis Ag | Pulmonale verabreichung von aminoglykosiden |
ES2425392T3 (es) | 2002-03-20 | 2013-10-15 | Mannkind Corporation | Cartucho para un aparato de inhalación |
JP4422794B2 (ja) | 2002-03-22 | 2010-02-24 | クリニカル・デザインズ・リミテッド | 投与装置及びその製作方法 |
UA80123C2 (en) * | 2002-04-09 | 2007-08-27 | Boehringer Ingelheim Pharma | Inhalation kit comprising inhalable powder of tiotropium |
AU2003303036A1 (en) * | 2002-12-13 | 2004-07-09 | Pfizer Products Inc. | Method of decreasing hepatic glucose output in diabetic patients |
US20050236296A1 (en) * | 2002-12-30 | 2005-10-27 | Nektar Therapeutics (Formerly Inhale Therapeutic Systems, Inc.) | Carry case for aerosolization apparatus |
GB0304000D0 (en) | 2003-02-21 | 2003-03-26 | Clinical Designs Ltd | Dispenser |
US7559325B2 (en) * | 2003-04-09 | 2009-07-14 | Novartis Pharma Ag | Aerosolization apparatus with air inlet shield |
ES2770035T3 (es) | 2003-04-11 | 2020-06-30 | Ptc Therapeutics Inc | Compuesto de ácido 1,2,4-oxadiazol benzoico y su uso para la supresión sin sentido y el tratamiento de enfermedades |
GB0313604D0 (en) * | 2003-06-12 | 2003-07-16 | Britannia Pharmaceuticals Ltd | Delivery device for powdered medicament |
US7318925B2 (en) * | 2003-08-08 | 2008-01-15 | Amgen Fremont, Inc. | Methods of use for antibodies against parathyroid hormone |
WO2005016111A2 (en) | 2003-08-08 | 2005-02-24 | Abgenix, Inc. | Antibodies directed to parathyroid hormone (pth) and uses thereof |
EP1692128A1 (en) | 2003-11-19 | 2006-08-23 | Signal Pharmaceuticals LLC | Indazole compounds and methods of use thereof as protein kinase inhibitors |
GB0327112D0 (en) | 2003-11-21 | 2003-12-24 | Clincial Designs Ltd | Dispenser and reservoir |
GB0328859D0 (en) | 2003-12-12 | 2004-01-14 | Clinical Designs Ltd | Dispenser and counter |
WO2005065756A2 (en) | 2003-12-30 | 2005-07-21 | Oriel Therapeutics, Inc. | Dry powder nebulizers and associated methods of dispensing dry powders |
ATE486064T1 (de) | 2004-08-20 | 2010-11-15 | Mannkind Corp | Katalyse der diketopiperazinsynthese |
PL1791542T3 (pl) | 2004-08-23 | 2015-11-30 | Mannkind Corp | Sole diketopiperazyny do dostarczania leków |
AU2005282065B2 (en) * | 2004-09-10 | 2013-02-07 | Pharmaorigin Aps | Methods for treating local tracheal, bronchial or alveolar bleeding or hemoptysis |
GB0425518D0 (en) | 2004-11-19 | 2004-12-22 | Clinical Designs Ltd | Substance source |
US7827983B2 (en) * | 2004-12-20 | 2010-11-09 | Hewlett-Packard Development Company, L.P. | Method for making a pharmaceutically active ingredient abuse-prevention device |
GB0428204D0 (en) * | 2004-12-23 | 2005-01-26 | Clinical Designs Ltd | Medicament container |
US20160345631A1 (en) | 2005-07-19 | 2016-12-01 | James Monsees | Portable devices for generating an inhalable vapor |
US9675109B2 (en) | 2005-07-19 | 2017-06-13 | J. T. International Sa | Method and system for vaporization of a substance |
CA2615718A1 (en) | 2005-07-22 | 2007-02-01 | Amgen Inc. | Aniline sulfonamide derivatives and their uses |
GB0518400D0 (en) | 2005-09-09 | 2005-10-19 | Clinical Designs Ltd | Dispenser |
AU2006290870B2 (en) | 2005-09-14 | 2013-02-28 | Mannkind Corporation | Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces |
CA2641872A1 (en) * | 2006-02-09 | 2007-08-16 | Kamada Ltd. | Alpha-i antitrypsin for treating exacerbation episodes of pulmonary diseases |
EP2497484A3 (en) | 2006-02-22 | 2012-11-07 | MannKind Corporation | A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent |
US7659287B2 (en) | 2006-06-08 | 2010-02-09 | Amgen Inc. | Benzamide derivatives and uses related thereto |
TW200808695A (en) | 2006-06-08 | 2008-02-16 | Amgen Inc | Benzamide derivatives and uses related thereto |
AU2007275301A1 (en) | 2006-07-20 | 2008-01-24 | Amgen Inc. | Substituted azole aromatic heterocycles as inhibitors of 11-beta-HSD-1 |
CA2673586A1 (en) | 2006-12-26 | 2008-07-24 | Amgen Inc. | N-cyclohexyl benzamides and benzeneacetamides as inhibitors of 11-beta-hydroxysteroid dehydrogenases |
US8991402B2 (en) | 2007-12-18 | 2015-03-31 | Pax Labs, Inc. | Aerosol devices and methods for inhaling a substance and uses thereof |
US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
DK2570147T3 (da) | 2008-06-13 | 2018-01-29 | Mannkind Corp | Tørpulverinhalator og system til lægemiddelindgivelse |
KR101628410B1 (ko) | 2008-06-20 | 2016-06-08 | 맨카인드 코포레이션 | 흡입 활동에 관한 실시간 프로파일링을 위한 대화형 장치 및 방법 |
TWI532497B (zh) | 2008-08-11 | 2016-05-11 | 曼凱公司 | 超快起作用胰島素之用途 |
US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
GB0904040D0 (en) | 2009-03-10 | 2009-04-22 | Euro Celtique Sa | Counter |
GB0904059D0 (en) | 2009-03-10 | 2009-04-22 | Euro Celtique Sa | Counter |
CA2754595C (en) | 2009-03-11 | 2017-06-27 | Mannkind Corporation | Apparatus, system and method for measuring resistance of an inhaler |
US8734845B2 (en) | 2009-06-12 | 2014-05-27 | Mannkind Corporation | Diketopiperazine microparticles with defined specific surface areas |
CA2778698A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
US9084864B1 (en) | 2010-03-04 | 2015-07-21 | Barthel LLC | Adaptor for breathing tube and method |
US8974771B2 (en) * | 2010-03-09 | 2015-03-10 | Penn-Century, Inc. | Apparatus and method for aerosol delivery to the lungs or other locations of the body |
RU2531455C2 (ru) | 2010-06-21 | 2014-10-20 | Маннкайнд Корпорейшн | Системы и способы доставки сухих порошковых лекарств |
EP2608829A4 (en) | 2010-08-23 | 2015-11-18 | Darren Rubin | SYSTEMS AND METHODS FOR AEROSOL SUPPLY WITH AIRFLOW REGULATION |
US9757528B2 (en) | 2010-08-23 | 2017-09-12 | Darren Rubin | Nebulizer having different negative pressure threshold settings |
MY180552A (en) | 2011-04-01 | 2020-12-02 | Mannkind Corp | Blister package for pharmaceutical cartridges |
WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
IL291500B2 (en) | 2011-08-16 | 2024-03-01 | Juul Labs Inc | Low temperature electronic evaporation device and methods |
WO2013063160A1 (en) | 2011-10-24 | 2013-05-02 | Mannkind Corporation | Methods and compositions for treating pain |
MY166314A (en) | 2011-12-30 | 2018-06-25 | Grifols Sa | Alpha1-proteinase inhibitor for delaying the onset or progression of pulmonary exacerbations |
FR2985909B1 (fr) * | 2012-01-20 | 2014-08-08 | Diffusion Tech Francaise Sarl | Dispositif de nebulisation pour aerosols medicaux |
WO2013151727A1 (en) * | 2012-04-03 | 2013-10-10 | Smith Medical Asd, Inc. | Heparin-bulking agent compositions and methods thereof |
CA2878457C (en) | 2012-07-12 | 2021-01-19 | Mannkind Corporation | Dry powder drug delivery systems and methods |
US10517530B2 (en) | 2012-08-28 | 2019-12-31 | Juul Labs, Inc. | Methods and devices for delivering and monitoring of tobacco, nicotine, or other substances |
WO2014066856A1 (en) | 2012-10-26 | 2014-05-01 | Mannkind Corporation | Inhalable influenza vaccine compositions and methods |
US10034988B2 (en) | 2012-11-28 | 2018-07-31 | Fontem Holdings I B.V. | Methods and devices for compound delivery |
US10279934B2 (en) | 2013-03-15 | 2019-05-07 | Juul Labs, Inc. | Fillable vaporizer cartridge and method of filling |
US10653180B2 (en) | 2013-06-14 | 2020-05-19 | Juul Labs, Inc. | Multiple heating elements with separate vaporizable materials in an electric vaporization device |
BR112015023168B1 (pt) | 2013-03-15 | 2021-08-10 | Mannkind Corporation | Composição de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina cristalina, método de produção de partículas de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina e uso de uma composição de dicetopiperazina cristalina |
KR20230013165A (ko) | 2013-05-06 | 2023-01-26 | 쥴 랩스, 인크. | 에어로졸 장치를 위한 니코틴 염 제제 및 그 방법 |
CN114848614A (zh) | 2013-07-18 | 2022-08-05 | 曼金德公司 | 热稳定性干粉药物组合物和方法 |
CA2920488C (en) | 2013-08-05 | 2022-04-26 | Mannkind Corporation | Insufflation apparatus and methods |
US10194693B2 (en) | 2013-09-20 | 2019-02-05 | Fontem Holdings 1 B.V. | Aerosol generating device |
CA2932464C (en) | 2013-12-05 | 2023-01-03 | Pax Labs, Inc. | Nicotine liquid formulations for aerosol devices and methods thereof |
USD842536S1 (en) | 2016-07-28 | 2019-03-05 | Juul Labs, Inc. | Vaporizer cartridge |
US10058129B2 (en) | 2013-12-23 | 2018-08-28 | Juul Labs, Inc. | Vaporization device systems and methods |
US10076139B2 (en) | 2013-12-23 | 2018-09-18 | Juul Labs, Inc. | Vaporizer apparatus |
USD825102S1 (en) | 2016-07-28 | 2018-08-07 | Juul Labs, Inc. | Vaporizer device with cartridge |
US10159282B2 (en) | 2013-12-23 | 2018-12-25 | Juul Labs, Inc. | Cartridge for use with a vaporizer device |
US20160366947A1 (en) | 2013-12-23 | 2016-12-22 | James Monsees | Vaporizer apparatus |
FI3491948T4 (fi) | 2013-12-23 | 2024-05-06 | Juul Labs International Inc | Höyrystyslaitejärjestelmiä |
US9549573B2 (en) | 2013-12-23 | 2017-01-24 | Pax Labs, Inc. | Vaporization device systems and methods |
US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
AU2015254999B2 (en) | 2014-04-28 | 2019-08-01 | Philip Morris Products S.A. | Flavoured nicotine powder inhaler |
EP3136894B1 (en) * | 2014-04-28 | 2019-07-31 | Philip Morris Products S.A. | Nicotine powder inhaler |
US11478021B2 (en) | 2014-05-16 | 2022-10-25 | Juul Labs, Inc. | Systems and methods for aerosolizing a vaporizable material |
US10857313B2 (en) * | 2014-07-01 | 2020-12-08 | Aerami Therapeutics, Inc. | Liquid nebulization systems and methods |
US11273271B2 (en) | 2014-07-01 | 2022-03-15 | Aerami Therapeutics, Inc. | Aerosolization system with flow restrictor and feedback device |
US10471222B2 (en) * | 2014-07-01 | 2019-11-12 | Dance Biopharm Inc. | Aerosolization system with flow restrictor and feedback device |
US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
AU2015338717B2 (en) | 2014-10-31 | 2018-12-20 | Glaxosmithkline Intellectual Property Development Limited | Powder formulation |
EP3821735A1 (en) | 2014-12-05 | 2021-05-19 | Juul Labs, Inc. | Calibrated dose control |
WO2017112452A1 (en) * | 2015-12-21 | 2017-06-29 | 3M Innovative Properties Company | Flow governor assemblies for use in medicinal inhalers |
WO2017112748A1 (en) | 2015-12-21 | 2017-06-29 | 3M Innovative Properties Company | Flow govenors for use in medicinal inhalers |
EP3413960B1 (en) | 2016-02-11 | 2021-03-31 | Juul Labs, Inc. | Fillable vaporizer cartridge and method of filling |
SG11201806801VA (en) | 2016-02-11 | 2018-09-27 | Juul Labs Inc | Securely attaching cartridges for vaporizer devices |
US10506829B2 (en) | 2016-02-26 | 2019-12-17 | Freelander Innovations USA, LLC | System and method for a vaporizer |
US10405582B2 (en) | 2016-03-10 | 2019-09-10 | Pax Labs, Inc. | Vaporization device with lip sensing |
USD849996S1 (en) | 2016-06-16 | 2019-05-28 | Pax Labs, Inc. | Vaporizer cartridge |
USD848057S1 (en) | 2016-06-23 | 2019-05-07 | Pax Labs, Inc. | Lid for a vaporizer |
USD851830S1 (en) | 2016-06-23 | 2019-06-18 | Pax Labs, Inc. | Combined vaporizer tamp and pick tool |
USD836541S1 (en) | 2016-06-23 | 2018-12-25 | Pax Labs, Inc. | Charging device |
US11660403B2 (en) | 2016-09-22 | 2023-05-30 | Juul Labs, Inc. | Leak-resistant vaporizer device |
WO2018132867A1 (en) * | 2017-01-18 | 2018-07-26 | Medical Developments International Limited | Inhaler device for inhalable liquids |
USD887632S1 (en) | 2017-09-14 | 2020-06-16 | Pax Labs, Inc. | Vaporizer cartridge |
EP3723790B1 (en) | 2017-12-12 | 2024-03-13 | Kamada Ltd | Methods of inducing immune tolerance and reducing anti-drug antibody response |
WO2019200274A1 (en) | 2018-04-12 | 2019-10-17 | MatRx Therapeutics Corporation | Compositions and methods for treating elastic fiber breakdown |
CN113384781B (zh) * | 2020-03-11 | 2024-03-29 | 李彤 | 一种egcg雾化*** |
CN114712336B (zh) * | 2020-12-22 | 2023-11-07 | 黄嘉若 | 一种用于肺部给药的水性气溶胶、制备方法和用途 |
US20220233471A1 (en) * | 2021-01-15 | 2022-07-28 | Aquestive Therapeutics, Inc. | Prodrug compositions and methods of treatment |
Family Cites Families (125)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US393869A (en) * | 1888-12-04 | Inhaler | ||
US957548A (en) * | 1909-12-27 | 1910-05-10 | Walter S Doane | Inhaler. |
US2586215A (en) | 1947-10-17 | 1952-02-19 | Hickok Mfg Co Inc | Necktie holder |
US2587215A (en) * | 1949-04-27 | 1952-02-26 | Frank P Priestly | Inhalator |
US2788784A (en) * | 1955-08-23 | 1957-04-16 | Herbert M Birch | Means for administering medication orally into the respiratory organs |
US3788310A (en) * | 1970-03-25 | 1974-01-29 | Westinghouse Electric Corp | Flow control apparatus |
GB1392945A (en) | 1972-08-23 | 1975-05-07 | Fisons Ltd | Inhalation device |
US4036919A (en) * | 1974-06-26 | 1977-07-19 | Inhalation Therapy Equipment, Inc. | Nebulizer-humidifier system |
US3991304A (en) * | 1975-05-19 | 1976-11-09 | Hillsman Dean | Respiratory biofeedback and performance evaluation system |
US4086918A (en) | 1976-02-11 | 1978-05-02 | Chesebrough-Pond's Inc. | Inhalation device |
US4170228A (en) | 1976-11-05 | 1979-10-09 | C. R. Bard, Inc. | Variable flow incentive spirometer |
US4106503A (en) | 1977-03-11 | 1978-08-15 | Richard R. Rosenthal | Metering system for stimulating bronchial spasm |
GB1598053A (en) | 1978-01-31 | 1981-09-16 | Fisons Ltd | Pocket inhaler |
US4274404A (en) * | 1979-04-13 | 1981-06-23 | American Safety Flight Systems, Inc. | Oxygen supply system controlled by user exhalation |
IT1116047B (it) | 1979-04-27 | 1986-02-10 | Sigma Tau Ind Farmaceuti | Dispositivo per la rapida inalazione di farmaci in polvere da parte di persone sofferenti di asma |
US4284083A (en) | 1979-05-29 | 1981-08-18 | Lester Victor E | Inhalation incentive device |
US4259951A (en) | 1979-07-30 | 1981-04-07 | Chesebrough-Pond's Inc. | Dual valve for respiratory device |
DE3023648A1 (de) | 1980-06-24 | 1982-01-21 | Jaeger, Erich, 8700 Würzburg | Einrichtung zur untersuchung der atemwege auf reizstoff-ueberempfindlichkeit |
US4391283A (en) | 1981-03-24 | 1983-07-05 | Whitman Medical Corporation | Incentive spirometer |
US4366947A (en) * | 1981-05-20 | 1983-01-04 | Amp Corporation | Calibrated gas-metering apparatus |
US4484577A (en) * | 1981-07-23 | 1984-11-27 | Key Pharmaceuticals, Inc. | Drug delivery method and inhalation device therefor |
US4442856A (en) * | 1981-08-18 | 1984-04-17 | Puritan-Bennett | Oxygen regulator and alarm system for an anesthesia machine |
US4533137A (en) | 1982-01-19 | 1985-08-06 | Healthscan Inc. | Pulmonary training method |
US4444202A (en) | 1982-03-31 | 1984-04-24 | Howard Rubin | Breathing exerciser |
CA1224992A (en) | 1982-10-08 | 1987-08-04 | Robert E. Newell | Device for administering medicament to patients |
US4778054A (en) | 1982-10-08 | 1988-10-18 | Glaxo Group Limited | Pack for administering medicaments to patients |
US4495944A (en) | 1983-02-07 | 1985-01-29 | Trutek Research, Inc. | Inhalation therapy apparatus |
US5743398A (en) * | 1984-05-22 | 1998-04-28 | Southpac Trust International, Inc. | Floral wrapper utilizing a breathable packaging material |
NZ209900A (en) | 1984-10-16 | 1989-08-29 | Univ Auckland | Automatic inhaler |
US4592348A (en) | 1984-12-17 | 1986-06-03 | Waters Iv William C | Aerosol inhaler |
FI88112C (fi) | 1985-07-30 | 1993-04-13 | Glaxo Group Ltd | Anordning foer administrering av laekemedel till patienter |
SE453566B (sv) | 1986-03-07 | 1988-02-15 | Draco Ab | Anordning vid pulverinhalatorer |
US4926852B1 (en) * | 1986-06-23 | 1995-05-23 | Univ Johns Hopkins | Medication delivery system phase one |
ES2051371T3 (es) | 1988-10-04 | 1994-06-16 | Univ Johns Hopkins | Inhalador de aerosoles. |
US5033655A (en) | 1989-02-15 | 1991-07-23 | Liquid Molding Systems Inc. | Dispensing package for fluid products and the like |
US4991745A (en) | 1989-04-25 | 1991-02-12 | Liquid Molding Systems, Inc. | Dispensing valve with trampoline-like construction |
WO1990013327A1 (en) | 1989-04-28 | 1990-11-15 | Riker Laboratories, Inc. | Dry powder inhalation device |
US4955371A (en) | 1989-05-08 | 1990-09-11 | Transtech Scientific, Inc. | Disposable inhalation activated, aerosol device for pulmonary medicine |
US5201308A (en) | 1990-02-14 | 1993-04-13 | Newhouse Michael T | Powder inhaler |
US5042467A (en) | 1990-03-28 | 1991-08-27 | Trudell Medical | Medication inhaler with fitting having a sonic signalling device |
DE4027391A1 (de) | 1990-08-30 | 1992-03-12 | Boehringer Ingelheim Kg | Treibgasfreies inhalationsgeraet |
DE4029183A1 (de) | 1990-09-14 | 1992-03-19 | Dieter Kuhn | Durchflussregler |
GB9021433D0 (en) | 1990-10-02 | 1990-11-14 | Atomic Energy Authority Uk | Power inhaler |
FR2667509B1 (fr) | 1990-10-04 | 1995-08-25 | Valois | Inhalateur a poudre, dispositif de conditionnement de microdoses de poudre sous forme de bandes adaptees a etre utilisees dans un inhalateur a poudre, et procede de fabrication de ces bandes. |
US5042472A (en) | 1990-10-15 | 1991-08-27 | Merck & Co., Inc. | Powder inhaler device |
GB9024760D0 (en) | 1990-11-14 | 1991-01-02 | Riker Laboratories Inc | Inhalation device and medicament carrier |
US5040527A (en) | 1990-12-18 | 1991-08-20 | Healthscan Products Inc. | Metered dose inhalation unit with slide means |
US5392768A (en) * | 1991-03-05 | 1995-02-28 | Aradigm | Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval |
AU651882B2 (en) | 1991-05-14 | 1994-08-04 | Visiomed Group Limited | Aerosol inhalation device |
US6055980A (en) | 1991-05-20 | 2000-05-02 | Dura Pharmaceuticals, Inc. | Dry powder inhaler |
ES2141108T3 (es) | 1991-07-02 | 2000-03-16 | Inhale Inc | Metodo y dispositivo para proporcionar medicamentos en aerosol. |
US5337740A (en) | 1991-08-01 | 1994-08-16 | New England Pharmaceuticals, Inc. | Inhalation devices |
US5161524A (en) | 1991-08-02 | 1992-11-10 | Glaxo Inc. | Dosage inhalator with air flow velocity regulating means |
US6119688A (en) | 1991-08-26 | 2000-09-19 | 3M Innovative Properties Company | Powder dispenser |
US5167506A (en) | 1991-10-24 | 1992-12-01 | Minnesota Mining And Manufacturing Company | Inhalation device training system |
US5396884A (en) * | 1991-11-15 | 1995-03-14 | Cimco, Inc. | High flow rate humidifier with baffle plates |
US5213236A (en) | 1991-12-06 | 1993-05-25 | Liquid Molding Systems, Inc. | Dispensing valve for packaging |
US5409144A (en) | 1991-12-06 | 1995-04-25 | Liquid Molding Systems Inc. | Dispensing valve for packaging |
DE4211475A1 (de) | 1991-12-14 | 1993-06-17 | Asta Medica Ag | Pulverinhalator |
US5320094A (en) | 1992-01-10 | 1994-06-14 | The Johns Hopkins University | Method of administering insulin |
EP0558879B1 (en) | 1992-03-04 | 1997-05-14 | Astra Aktiebolag | Disposable inhaler |
US5639441A (en) * | 1992-03-06 | 1997-06-17 | Board Of Regents Of University Of Colorado | Methods for fine particle formation |
US5785049A (en) | 1994-09-21 | 1998-07-28 | Inhale Therapeutic Systems | Method and apparatus for dispersion of dry powder medicaments |
US5284133A (en) | 1992-07-23 | 1994-02-08 | Armstrong Pharmaceuticals, Inc. | Inhalation device with a dose-timer, an actuator mechanism, and patient compliance monitoring means |
US5333106A (en) | 1992-10-09 | 1994-07-26 | Circadian, Inc. | Apparatus and visual display method for training in the power use of aerosol pharmaceutical inhalers |
DE4239402A1 (de) | 1992-11-24 | 1994-05-26 | Bayer Ag | Pulverinhalator |
US5888477A (en) * | 1993-01-29 | 1999-03-30 | Aradigm Corporation | Use of monomeric insulin as a means for improving the bioavailability of inhaled insulin |
US5672581A (en) | 1993-01-29 | 1997-09-30 | Aradigm Corporation | Method of administration of insulin |
US5507277A (en) * | 1993-01-29 | 1996-04-16 | Aradigm Corporation | Lockout device for controlled release of drug from patient-activateddispenser |
AU6167894A (en) | 1993-01-29 | 1994-08-15 | Miris Medical Corporation | Intrapulmonary delivery of hormones |
US5743250A (en) | 1993-01-29 | 1998-04-28 | Aradigm Corporation | Insulin delivery enhanced by coached breathing |
US5364838A (en) | 1993-01-29 | 1994-11-15 | Miris Medical Corporation | Method of administration of insulin |
US5873358A (en) | 1993-01-29 | 1999-02-23 | Aradigm Corporation | Method of maintaining a diabetic patient's blood glucose level in a desired range |
US5558085A (en) | 1993-01-29 | 1996-09-24 | Aradigm Corporation | Intrapulmonary delivery of peptide drugs |
FR2701399B1 (fr) | 1993-02-16 | 1995-03-31 | Valois | Dispositif portatif de pulvérisation à actionnement déclenché par l'inhalation. |
US5437271A (en) | 1993-04-06 | 1995-08-01 | Minnesota Mining And Manufacturing Company | Deagglomerators for dry powder inhalers |
US5349947A (en) * | 1993-07-15 | 1994-09-27 | Newhouse Michael T | Dry powder inhaler and process that explosively discharges a dose of powder and gas from a soft plastic pillow |
DK0714314T3 (da) | 1993-08-18 | 1999-06-23 | Fisons Plc | Inhalator med åndedrætsregulering |
US5655520A (en) | 1993-08-23 | 1997-08-12 | Howe; Harvey James | Flexible valve for administering constant flow rates of medicine from a nebulizer |
GB9326574D0 (en) | 1993-12-31 | 1994-03-02 | King S College London | Dry power inhalers |
US6102036A (en) | 1994-04-12 | 2000-08-15 | Smoke-Stop | Breath activated inhaler |
US5483954A (en) | 1994-06-10 | 1996-01-16 | Mecikalski; Mark B. | Inhaler and medicated package |
US5509404A (en) * | 1994-07-11 | 1996-04-23 | Aradigm Corporation | Intrapulmonary drug delivery within therapeutically relevant inspiratory flow/volume values |
US5653223A (en) | 1994-09-08 | 1997-08-05 | Pruitt; Michael D. | Accurately controlled portable nebulizer |
AU697676B2 (en) | 1994-09-21 | 1998-10-15 | Nektar Therapeutics | Apparatus and methods for dispersing dry powder medicaments |
US5993421A (en) * | 1994-12-02 | 1999-11-30 | Science Incorporated | Medicament dispenser |
US5552380A (en) * | 1994-12-15 | 1996-09-03 | International Flavors & Fragrances Inc. | Perfume uses of phenyl alkanol derivatives |
SE9404439D0 (sv) | 1994-12-21 | 1994-12-21 | Astra Ab | Inhalation device |
US5522380A (en) | 1995-01-18 | 1996-06-04 | Dwork; Paul | Metered dose medication adaptor with improved incentive spirometer |
US5568910A (en) * | 1995-03-02 | 1996-10-29 | Delmarva Laboratories, Inc. | Anesthesia machine |
US5513630A (en) | 1995-03-08 | 1996-05-07 | Century; Theodore J. | Powder dispenser |
CA2216443A1 (en) * | 1995-03-31 | 1996-10-03 | Aradigm Corporation | Intrapulmonary delivery of hematopoietic drug |
US5586550A (en) | 1995-08-31 | 1996-12-24 | Fluid Propulsion Technologies, Inc. | Apparatus and methods for the delivery of therapeutic liquids to the respiratory system |
US5921237A (en) | 1995-04-24 | 1999-07-13 | Dura Pharmaceuticals, Inc. | Dry powder inhaler |
US5622166A (en) | 1995-04-24 | 1997-04-22 | Dura Pharmaceuticals, Inc. | Dry powder inhaler delivery system |
US5654007A (en) | 1995-06-07 | 1997-08-05 | Inhale Therapeutic Systems | Methods and system for processing dispersible fine powders |
US5826571A (en) | 1995-06-08 | 1998-10-27 | Innovative Devices, Llc | Device for use with metered dose inhalers (MDIS) |
GB9513218D0 (en) | 1995-06-29 | 1995-09-06 | Fisons Plc | Inhalation device and method |
DE19523516C1 (de) | 1995-06-30 | 1996-10-31 | Asta Medica Ag | Inhalator zum Verabreichen von Medikamenten aus Blisterpackungen |
US5692496A (en) | 1995-08-02 | 1997-12-02 | Innovative Devices, Llc | Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament |
US5988163A (en) | 1995-08-02 | 1999-11-23 | Innovative Devices | Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of delivery of medicament |
US5823183A (en) | 1995-08-02 | 1998-10-20 | Innovative Devices | Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament |
US5603315A (en) * | 1995-08-14 | 1997-02-18 | Reliable Engineering | Multiple mode oxygen delivery system |
SE9503344D0 (sv) * | 1995-09-27 | 1995-09-27 | Astra Ab | Inhalation device |
CN1213974A (zh) | 1996-01-03 | 1999-04-14 | 葛兰素集团有限公司 | 吸入器具 |
US5699789A (en) | 1996-03-11 | 1997-12-23 | Hendricks; Mark R. | Dry powder inhaler |
DE19613185A1 (de) | 1996-04-02 | 1997-10-09 | Pfeiffer Erich Gmbh & Co Kg | Dosiereinrichtung für strömungsfähige Medien wie Pulver/Luft-Dispersionen |
US5875776A (en) | 1996-04-09 | 1999-03-02 | Vivorx Pharmaceuticals, Inc. | Dry powder inhaler |
GB2312848B (en) | 1996-04-26 | 1999-11-17 | Bespak Plc | Controlled flow inhalers |
US5839430A (en) * | 1996-04-26 | 1998-11-24 | Cama; Joseph | Combination inhaler and peak flow rate meter |
US5826633A (en) | 1996-04-26 | 1998-10-27 | Inhale Therapeutic Systems | Powder filling systems, apparatus and methods |
CA2252814A1 (en) | 1996-04-29 | 1997-11-06 | Dura Pharmaceuticals, Inc. | Methods of dry powder inhalation |
AUPN973596A0 (en) * | 1996-05-08 | 1996-05-30 | Resmed Limited | Control of delivery pressure in cpap treatment or assisted respiration |
US5813401A (en) | 1996-10-15 | 1998-09-29 | Radcliff; Janet H. | Nebulizer automatic control valve |
SE9700422D0 (sv) | 1997-02-07 | 1997-02-07 | Astra Ab | Single dose inhaler II |
US6006747A (en) | 1997-03-20 | 1999-12-28 | Dura Pharmaceuticals, Inc. | Dry powder inhaler |
US6131571A (en) * | 1997-04-30 | 2000-10-17 | University Of Florida | Ventilation apparatus and anesthesia delivery system |
DE69829969T2 (de) * | 1997-07-25 | 2006-03-09 | Minnesota Innovative Technologies & Instruments Corp. (Miti), Lino Lakes | Steuervorrichtung zum zuführen von zusätzlichem atmungssauerstoff |
CA2212430A1 (en) | 1997-08-07 | 1999-02-07 | George Volgyesi | Inhalation device |
US5855202A (en) | 1997-10-08 | 1999-01-05 | Andrade; Joseph R. | Aerosol holding chamber for a metered-dose inhaler |
US6067984A (en) * | 1997-10-14 | 2000-05-30 | Piper; Samuel David | Pulmonary modulator apparatus |
US6032667A (en) * | 1997-10-30 | 2000-03-07 | Instrumentarium Corporation | Variable orifice pulse valve |
US6116238A (en) | 1997-12-02 | 2000-09-12 | Dura Pharmaceuticals, Inc. | Dry powder inhaler |
US6076523A (en) * | 1998-01-15 | 2000-06-20 | Nellcor Puritan Bennett | Oxygen blending in a piston ventilator |
US6142146A (en) | 1998-06-12 | 2000-11-07 | Microdose Technologies, Inc. | Inhalation device |
-
1999
- 1999-03-11 SI SI9920017A patent/SI20413A/sl not_active IP Right Cessation
- 1999-03-11 EA EA200000823A patent/EA003196B1/ru not_active IP Right Cessation
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- 1999-03-11 HU HU0100848A patent/HUP0100848A3/hu unknown
- 1999-03-11 SK SK1363-2000A patent/SK13632000A3/sk unknown
- 1999-03-11 RO ROA200000909A patent/RO121834B1/ro unknown
- 1999-03-11 EE EEP200000546A patent/EE200000546A/xx unknown
- 1999-03-11 AU AU29803/99A patent/AU750539B2/en not_active Ceased
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- 1999-03-11 US US09/266,720 patent/US6655379B2/en not_active Expired - Lifetime
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- 1999-03-11 ID IDW20001760A patent/ID26237A/id unknown
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- 1999-03-11 EP EP99911071A patent/EP1066074A1/en not_active Withdrawn
- 1999-03-15 TN TNTNSN99038A patent/TNSN99038A1/fr unknown
- 1999-03-15 TW TW088103965A patent/TWI228998B/zh not_active IP Right Cessation
- 1999-03-15 PE PE1999000202A patent/PE20000346A1/es not_active Application Discontinuation
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- 1999-03-15 DZ DZ990045A patent/DZ2744A1/xx active
- 1999-03-15 MA MA25495A patent/MA26033A1/fr unknown
- 1999-03-15 UY UY25432A patent/UY25432A1/es not_active Application Discontinuation
- 1999-03-15 AR ARP990101116A patent/AR018161A1/es unknown
- 1999-03-16 PA PA19998468901A patent/PA8468901A1/es unknown
- 1999-03-16 CO CO99016181A patent/CO5060522A1/es unknown
- 1999-03-16 HN HN1999000028A patent/HN1999000028A/es unknown
- 1999-03-16 HR HR60/078,214A patent/HRP990081A2/hr not_active Application Discontinuation
- 1999-05-31 SA SA99200198A patent/SA99200198B1/ar unknown
-
2000
- 2000-08-22 IS IS5595A patent/IS5595A/is unknown
- 2000-08-28 BG BG104720A patent/BG65091B1/bg unknown
- 2000-09-15 NO NO20004627A patent/NO20004627L/no not_active Application Discontinuation
- 2000-09-15 HR HR20000608A patent/HRP20000608A2/hr not_active Application Discontinuation
- 2000-09-22 LV LVP-00-129A patent/LV12586B/en unknown
-
2003
- 2003-07-25 US US10/627,591 patent/US20050090798A1/en not_active Abandoned
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