IL138153A0 - Methods and devices for delivering aerosolized active agents - Google Patents

Methods and devices for delivering aerosolized active agents

Info

Publication number
IL138153A0
IL138153A0 IL13815399A IL13815399A IL138153A0 IL 138153 A0 IL138153 A0 IL 138153A0 IL 13815399 A IL13815399 A IL 13815399A IL 13815399 A IL13815399 A IL 13815399A IL 138153 A0 IL138153 A0 IL 138153A0
Authority
IL
Israel
Prior art keywords
methods
devices
active agents
aerosolized active
delivering aerosolized
Prior art date
Application number
IL13815399A
Other languages
English (en)
Original Assignee
Inhale Therapeutic Syst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inhale Therapeutic Syst filed Critical Inhale Therapeutic Syst
Publication of IL138153A0 publication Critical patent/IL138153A0/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00Inhalators
    • A61M15/0001Details of inhalators; Constructional features thereof
    • A61M15/002Details of inhalators; Constructional features thereof with air flow regulating means
IL13815399A 1998-03-16 1999-03-11 Methods and devices for delivering aerosolized active agents IL138153A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7821498P 1998-03-16 1998-03-16
US7821298P 1998-03-16 1998-03-16
PCT/US1999/004654 WO1999047196A1 (en) 1998-03-16 1999-03-11 Aerosolized active agent delivery

Publications (1)

Publication Number Publication Date
IL138153A0 true IL138153A0 (en) 2001-10-31

Family

ID=26760240

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13815399A IL138153A0 (en) 1998-03-16 1999-03-11 Methods and devices for delivering aerosolized active agents

Country Status (42)

Country Link
US (2) US6655379B2 (xx)
EP (1) EP1066074A1 (xx)
JP (1) JP4195191B2 (xx)
KR (1) KR100620338B1 (xx)
CN (1) CN1292714B (xx)
AP (1) AP1342A (xx)
AR (1) AR018161A1 (xx)
AU (1) AU750539B2 (xx)
BG (1) BG65091B1 (xx)
BR (1) BR9908771A (xx)
CA (1) CA2322045C (xx)
CO (1) CO5060522A1 (xx)
DZ (1) DZ2744A1 (xx)
EA (1) EA003196B1 (xx)
EE (1) EE200000546A (xx)
GE (1) GEP20043260B (xx)
HN (1) HN1999000028A (xx)
HR (2) HRP990081A2 (xx)
HU (1) HUP0100848A3 (xx)
ID (1) ID26237A (xx)
IL (1) IL138153A0 (xx)
IS (1) IS5595A (xx)
LT (1) LT4818B (xx)
LV (1) LV12586B (xx)
MA (1) MA26033A1 (xx)
MY (1) MY131803A (xx)
NO (1) NO20004627L (xx)
NZ (1) NZ506289A (xx)
OA (1) OA11529A (xx)
PA (1) PA8468901A1 (xx)
PE (1) PE20000346A1 (xx)
PL (1) PL343276A1 (xx)
RO (1) RO121834B1 (xx)
SA (1) SA99200198B1 (xx)
SI (1) SI20413A (xx)
SK (1) SK13632000A3 (xx)
TN (1) TNSN99038A1 (xx)
TR (1) TR200002692T2 (xx)
TW (1) TWI228998B (xx)
UY (1) UY25432A1 (xx)
WO (1) WO1999047196A1 (xx)
YU (1) YU56600A (xx)

Families Citing this family (127)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
US6309671B1 (en) * 1995-04-14 2001-10-30 Inhale Therapeutic Systems Stable glassy state powder formulations
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
GB9807232D0 (en) * 1998-04-03 1998-06-03 Univ Cardiff Aerosol composition
UA73924C2 (en) * 1998-10-09 2005-10-17 Nektar Therapeutics Device for delivering active agent formulation to lungs of human patient
GB2353222B (en) * 1999-06-23 2001-09-19 Cambridge Consultants Inhalers
US9006175B2 (en) 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
US6606992B1 (en) 1999-06-30 2003-08-19 Nektar Therapeutics Systems and methods for aerosolizing pharmaceutical formulations
US7305986B1 (en) 1999-07-23 2007-12-11 Mannkind Corporation Unit dose capsules for use in a dry powder inhaler
US7464706B2 (en) 1999-07-23 2008-12-16 Mannkind Corporation Unit dose cartridge and dry powder inhaler
JP4711520B2 (ja) * 2000-03-21 2011-06-29 日本ケミカルリサーチ株式会社 生理活性ペプチド含有粉末
PE20011227A1 (es) * 2000-04-17 2002-01-07 Chiesi Farma Spa Formulaciones farmaceuticas para inhaladores de polvo seco en la forma de aglomerados duros
MXPA02001323A (es) 2000-05-10 2004-07-16 Alliance Pharma Microgranulos con base fosfolipida para la liberacion de farmaco.
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
US7744855B2 (en) 2000-06-27 2010-06-29 Vectura Limited Method of making particles for use in a pharmaceutical composition
US6339107B1 (en) 2000-08-02 2002-01-15 Syntex (U.S.A.) Llc Methods for treatment of Emphysema using 13-cis retinoic acid
EP1935869A1 (en) 2000-10-02 2008-06-25 F. Hoffmann-La Roche Ag Retinoids for the treatment of emphysema
US7049283B2 (en) 2000-12-06 2006-05-23 Novartis Ag Pharmaceutical compositions for the oral delivery of pharmacologically active agents
US6782887B2 (en) * 2001-01-12 2004-08-31 Becton, Dickinson And Company Medicament respiratory delivery device and cartridge
ES2431634T3 (es) 2001-06-20 2013-11-27 Novartis Ag Dispositivo de administración de aerosol
GB2380946A (en) * 2001-08-31 2003-04-23 Medic Aid Ltd Nebuliser arrangement
ATE508735T1 (de) 2001-12-19 2011-05-15 Novartis Ag Pulmonale verabreichung von aminoglykosiden
ES2425392T3 (es) 2002-03-20 2013-10-15 Mannkind Corporation Cartucho para un aparato de inhalación
JP4422794B2 (ja) 2002-03-22 2010-02-24 クリニカル・デザインズ・リミテッド 投与装置及びその製作方法
UA80123C2 (en) * 2002-04-09 2007-08-27 Boehringer Ingelheim Pharma Inhalation kit comprising inhalable powder of tiotropium
AU2003303036A1 (en) * 2002-12-13 2004-07-09 Pfizer Products Inc. Method of decreasing hepatic glucose output in diabetic patients
US20050236296A1 (en) * 2002-12-30 2005-10-27 Nektar Therapeutics (Formerly Inhale Therapeutic Systems, Inc.) Carry case for aerosolization apparatus
GB0304000D0 (en) 2003-02-21 2003-03-26 Clinical Designs Ltd Dispenser
US7559325B2 (en) * 2003-04-09 2009-07-14 Novartis Pharma Ag Aerosolization apparatus with air inlet shield
ES2770035T3 (es) 2003-04-11 2020-06-30 Ptc Therapeutics Inc Compuesto de ácido 1,2,4-oxadiazol benzoico y su uso para la supresión sin sentido y el tratamiento de enfermedades
GB0313604D0 (en) * 2003-06-12 2003-07-16 Britannia Pharmaceuticals Ltd Delivery device for powdered medicament
US7318925B2 (en) * 2003-08-08 2008-01-15 Amgen Fremont, Inc. Methods of use for antibodies against parathyroid hormone
WO2005016111A2 (en) 2003-08-08 2005-02-24 Abgenix, Inc. Antibodies directed to parathyroid hormone (pth) and uses thereof
EP1692128A1 (en) 2003-11-19 2006-08-23 Signal Pharmaceuticals LLC Indazole compounds and methods of use thereof as protein kinase inhibitors
GB0327112D0 (en) 2003-11-21 2003-12-24 Clincial Designs Ltd Dispenser and reservoir
GB0328859D0 (en) 2003-12-12 2004-01-14 Clinical Designs Ltd Dispenser and counter
WO2005065756A2 (en) 2003-12-30 2005-07-21 Oriel Therapeutics, Inc. Dry powder nebulizers and associated methods of dispensing dry powders
ATE486064T1 (de) 2004-08-20 2010-11-15 Mannkind Corp Katalyse der diketopiperazinsynthese
PL1791542T3 (pl) 2004-08-23 2015-11-30 Mannkind Corp Sole diketopiperazyny do dostarczania leków
AU2005282065B2 (en) * 2004-09-10 2013-02-07 Pharmaorigin Aps Methods for treating local tracheal, bronchial or alveolar bleeding or hemoptysis
GB0425518D0 (en) 2004-11-19 2004-12-22 Clinical Designs Ltd Substance source
US7827983B2 (en) * 2004-12-20 2010-11-09 Hewlett-Packard Development Company, L.P. Method for making a pharmaceutically active ingredient abuse-prevention device
GB0428204D0 (en) * 2004-12-23 2005-01-26 Clinical Designs Ltd Medicament container
US20160345631A1 (en) 2005-07-19 2016-12-01 James Monsees Portable devices for generating an inhalable vapor
US9675109B2 (en) 2005-07-19 2017-06-13 J. T. International Sa Method and system for vaporization of a substance
CA2615718A1 (en) 2005-07-22 2007-02-01 Amgen Inc. Aniline sulfonamide derivatives and their uses
GB0518400D0 (en) 2005-09-09 2005-10-19 Clinical Designs Ltd Dispenser
AU2006290870B2 (en) 2005-09-14 2013-02-28 Mannkind Corporation Method of drug formulation based on increasing the affinity of active agents for crystalline microparticle surfaces
CA2641872A1 (en) * 2006-02-09 2007-08-16 Kamada Ltd. Alpha-i antitrypsin for treating exacerbation episodes of pulmonary diseases
EP2497484A3 (en) 2006-02-22 2012-11-07 MannKind Corporation A method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
US7659287B2 (en) 2006-06-08 2010-02-09 Amgen Inc. Benzamide derivatives and uses related thereto
TW200808695A (en) 2006-06-08 2008-02-16 Amgen Inc Benzamide derivatives and uses related thereto
AU2007275301A1 (en) 2006-07-20 2008-01-24 Amgen Inc. Substituted azole aromatic heterocycles as inhibitors of 11-beta-HSD-1
CA2673586A1 (en) 2006-12-26 2008-07-24 Amgen Inc. N-cyclohexyl benzamides and benzeneacetamides as inhibitors of 11-beta-hydroxysteroid dehydrogenases
US8991402B2 (en) 2007-12-18 2015-03-31 Pax Labs, Inc. Aerosol devices and methods for inhaling a substance and uses thereof
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
DK2570147T3 (da) 2008-06-13 2018-01-29 Mannkind Corp Tørpulverinhalator og system til lægemiddelindgivelse
KR101628410B1 (ko) 2008-06-20 2016-06-08 맨카인드 코포레이션 흡입 활동에 관한 실시간 프로파일링을 위한 대화형 장치 및 방법
TWI532497B (zh) 2008-08-11 2016-05-11 曼凱公司 超快起作用胰島素之用途
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
GB0904040D0 (en) 2009-03-10 2009-04-22 Euro Celtique Sa Counter
GB0904059D0 (en) 2009-03-10 2009-04-22 Euro Celtique Sa Counter
CA2754595C (en) 2009-03-11 2017-06-27 Mannkind Corporation Apparatus, system and method for measuring resistance of an inhaler
US8734845B2 (en) 2009-06-12 2014-05-27 Mannkind Corporation Diketopiperazine microparticles with defined specific surface areas
CA2778698A1 (en) 2009-11-03 2011-05-12 Mannkind Corporation An apparatus and method for simulating inhalation efforts
US9084864B1 (en) 2010-03-04 2015-07-21 Barthel LLC Adaptor for breathing tube and method
US8974771B2 (en) * 2010-03-09 2015-03-10 Penn-Century, Inc. Apparatus and method for aerosol delivery to the lungs or other locations of the body
RU2531455C2 (ru) 2010-06-21 2014-10-20 Маннкайнд Корпорейшн Системы и способы доставки сухих порошковых лекарств
EP2608829A4 (en) 2010-08-23 2015-11-18 Darren Rubin SYSTEMS AND METHODS FOR AEROSOL SUPPLY WITH AIRFLOW REGULATION
US9757528B2 (en) 2010-08-23 2017-09-12 Darren Rubin Nebulizer having different negative pressure threshold settings
MY180552A (en) 2011-04-01 2020-12-02 Mannkind Corp Blister package for pharmaceutical cartridges
WO2012174472A1 (en) 2011-06-17 2012-12-20 Mannkind Corporation High capacity diketopiperazine microparticles
IL291500B2 (en) 2011-08-16 2024-03-01 Juul Labs Inc Low temperature electronic evaporation device and methods
WO2013063160A1 (en) 2011-10-24 2013-05-02 Mannkind Corporation Methods and compositions for treating pain
MY166314A (en) 2011-12-30 2018-06-25 Grifols Sa Alpha1-proteinase inhibitor for delaying the onset or progression of pulmonary exacerbations
FR2985909B1 (fr) * 2012-01-20 2014-08-08 Diffusion Tech Francaise Sarl Dispositif de nebulisation pour aerosols medicaux
WO2013151727A1 (en) * 2012-04-03 2013-10-10 Smith Medical Asd, Inc. Heparin-bulking agent compositions and methods thereof
CA2878457C (en) 2012-07-12 2021-01-19 Mannkind Corporation Dry powder drug delivery systems and methods
US10517530B2 (en) 2012-08-28 2019-12-31 Juul Labs, Inc. Methods and devices for delivering and monitoring of tobacco, nicotine, or other substances
WO2014066856A1 (en) 2012-10-26 2014-05-01 Mannkind Corporation Inhalable influenza vaccine compositions and methods
US10034988B2 (en) 2012-11-28 2018-07-31 Fontem Holdings I B.V. Methods and devices for compound delivery
US10279934B2 (en) 2013-03-15 2019-05-07 Juul Labs, Inc. Fillable vaporizer cartridge and method of filling
US10653180B2 (en) 2013-06-14 2020-05-19 Juul Labs, Inc. Multiple heating elements with separate vaporizable materials in an electric vaporization device
BR112015023168B1 (pt) 2013-03-15 2021-08-10 Mannkind Corporation Composição de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina cristalina, método de produção de partículas de 3,6-bis(n-fumaril-4-aminobutil)-2,5-dicetopiperazina e uso de uma composição de dicetopiperazina cristalina
KR20230013165A (ko) 2013-05-06 2023-01-26 쥴 랩스, 인크. 에어로졸 장치를 위한 니코틴 염 제제 및 그 방법
CN114848614A (zh) 2013-07-18 2022-08-05 曼金德公司 热稳定性干粉药物组合物和方法
CA2920488C (en) 2013-08-05 2022-04-26 Mannkind Corporation Insufflation apparatus and methods
US10194693B2 (en) 2013-09-20 2019-02-05 Fontem Holdings 1 B.V. Aerosol generating device
CA2932464C (en) 2013-12-05 2023-01-03 Pax Labs, Inc. Nicotine liquid formulations for aerosol devices and methods thereof
USD842536S1 (en) 2016-07-28 2019-03-05 Juul Labs, Inc. Vaporizer cartridge
US10058129B2 (en) 2013-12-23 2018-08-28 Juul Labs, Inc. Vaporization device systems and methods
US10076139B2 (en) 2013-12-23 2018-09-18 Juul Labs, Inc. Vaporizer apparatus
USD825102S1 (en) 2016-07-28 2018-08-07 Juul Labs, Inc. Vaporizer device with cartridge
US10159282B2 (en) 2013-12-23 2018-12-25 Juul Labs, Inc. Cartridge for use with a vaporizer device
US20160366947A1 (en) 2013-12-23 2016-12-22 James Monsees Vaporizer apparatus
FI3491948T4 (fi) 2013-12-23 2024-05-06 Juul Labs International Inc Höyrystyslaitejärjestelmiä
US9549573B2 (en) 2013-12-23 2017-01-24 Pax Labs, Inc. Vaporization device systems and methods
US10307464B2 (en) 2014-03-28 2019-06-04 Mannkind Corporation Use of ultrarapid acting insulin
AU2015254999B2 (en) 2014-04-28 2019-08-01 Philip Morris Products S.A. Flavoured nicotine powder inhaler
EP3136894B1 (en) * 2014-04-28 2019-07-31 Philip Morris Products S.A. Nicotine powder inhaler
US11478021B2 (en) 2014-05-16 2022-10-25 Juul Labs, Inc. Systems and methods for aerosolizing a vaporizable material
US10857313B2 (en) * 2014-07-01 2020-12-08 Aerami Therapeutics, Inc. Liquid nebulization systems and methods
US11273271B2 (en) 2014-07-01 2022-03-15 Aerami Therapeutics, Inc. Aerosolization system with flow restrictor and feedback device
US10471222B2 (en) * 2014-07-01 2019-11-12 Dance Biopharm Inc. Aerosolization system with flow restrictor and feedback device
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
AU2015338717B2 (en) 2014-10-31 2018-12-20 Glaxosmithkline Intellectual Property Development Limited Powder formulation
EP3821735A1 (en) 2014-12-05 2021-05-19 Juul Labs, Inc. Calibrated dose control
WO2017112452A1 (en) * 2015-12-21 2017-06-29 3M Innovative Properties Company Flow governor assemblies for use in medicinal inhalers
WO2017112748A1 (en) 2015-12-21 2017-06-29 3M Innovative Properties Company Flow govenors for use in medicinal inhalers
EP3413960B1 (en) 2016-02-11 2021-03-31 Juul Labs, Inc. Fillable vaporizer cartridge and method of filling
SG11201806801VA (en) 2016-02-11 2018-09-27 Juul Labs Inc Securely attaching cartridges for vaporizer devices
US10506829B2 (en) 2016-02-26 2019-12-17 Freelander Innovations USA, LLC System and method for a vaporizer
US10405582B2 (en) 2016-03-10 2019-09-10 Pax Labs, Inc. Vaporization device with lip sensing
USD849996S1 (en) 2016-06-16 2019-05-28 Pax Labs, Inc. Vaporizer cartridge
USD848057S1 (en) 2016-06-23 2019-05-07 Pax Labs, Inc. Lid for a vaporizer
USD851830S1 (en) 2016-06-23 2019-06-18 Pax Labs, Inc. Combined vaporizer tamp and pick tool
USD836541S1 (en) 2016-06-23 2018-12-25 Pax Labs, Inc. Charging device
US11660403B2 (en) 2016-09-22 2023-05-30 Juul Labs, Inc. Leak-resistant vaporizer device
WO2018132867A1 (en) * 2017-01-18 2018-07-26 Medical Developments International Limited Inhaler device for inhalable liquids
USD887632S1 (en) 2017-09-14 2020-06-16 Pax Labs, Inc. Vaporizer cartridge
EP3723790B1 (en) 2017-12-12 2024-03-13 Kamada Ltd Methods of inducing immune tolerance and reducing anti-drug antibody response
WO2019200274A1 (en) 2018-04-12 2019-10-17 MatRx Therapeutics Corporation Compositions and methods for treating elastic fiber breakdown
CN113384781B (zh) * 2020-03-11 2024-03-29 李彤 一种egcg雾化***
CN114712336B (zh) * 2020-12-22 2023-11-07 黄嘉若 一种用于肺部给药的水性气溶胶、制备方法和用途
US20220233471A1 (en) * 2021-01-15 2022-07-28 Aquestive Therapeutics, Inc. Prodrug compositions and methods of treatment

Family Cites Families (125)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US393869A (en) * 1888-12-04 Inhaler
US957548A (en) * 1909-12-27 1910-05-10 Walter S Doane Inhaler.
US2586215A (en) 1947-10-17 1952-02-19 Hickok Mfg Co Inc Necktie holder
US2587215A (en) * 1949-04-27 1952-02-26 Frank P Priestly Inhalator
US2788784A (en) * 1955-08-23 1957-04-16 Herbert M Birch Means for administering medication orally into the respiratory organs
US3788310A (en) * 1970-03-25 1974-01-29 Westinghouse Electric Corp Flow control apparatus
GB1392945A (en) 1972-08-23 1975-05-07 Fisons Ltd Inhalation device
US4036919A (en) * 1974-06-26 1977-07-19 Inhalation Therapy Equipment, Inc. Nebulizer-humidifier system
US3991304A (en) * 1975-05-19 1976-11-09 Hillsman Dean Respiratory biofeedback and performance evaluation system
US4086918A (en) 1976-02-11 1978-05-02 Chesebrough-Pond's Inc. Inhalation device
US4170228A (en) 1976-11-05 1979-10-09 C. R. Bard, Inc. Variable flow incentive spirometer
US4106503A (en) 1977-03-11 1978-08-15 Richard R. Rosenthal Metering system for stimulating bronchial spasm
GB1598053A (en) 1978-01-31 1981-09-16 Fisons Ltd Pocket inhaler
US4274404A (en) * 1979-04-13 1981-06-23 American Safety Flight Systems, Inc. Oxygen supply system controlled by user exhalation
IT1116047B (it) 1979-04-27 1986-02-10 Sigma Tau Ind Farmaceuti Dispositivo per la rapida inalazione di farmaci in polvere da parte di persone sofferenti di asma
US4284083A (en) 1979-05-29 1981-08-18 Lester Victor E Inhalation incentive device
US4259951A (en) 1979-07-30 1981-04-07 Chesebrough-Pond's Inc. Dual valve for respiratory device
DE3023648A1 (de) 1980-06-24 1982-01-21 Jaeger, Erich, 8700 Würzburg Einrichtung zur untersuchung der atemwege auf reizstoff-ueberempfindlichkeit
US4391283A (en) 1981-03-24 1983-07-05 Whitman Medical Corporation Incentive spirometer
US4366947A (en) * 1981-05-20 1983-01-04 Amp Corporation Calibrated gas-metering apparatus
US4484577A (en) * 1981-07-23 1984-11-27 Key Pharmaceuticals, Inc. Drug delivery method and inhalation device therefor
US4442856A (en) * 1981-08-18 1984-04-17 Puritan-Bennett Oxygen regulator and alarm system for an anesthesia machine
US4533137A (en) 1982-01-19 1985-08-06 Healthscan Inc. Pulmonary training method
US4444202A (en) 1982-03-31 1984-04-24 Howard Rubin Breathing exerciser
CA1224992A (en) 1982-10-08 1987-08-04 Robert E. Newell Device for administering medicament to patients
US4778054A (en) 1982-10-08 1988-10-18 Glaxo Group Limited Pack for administering medicaments to patients
US4495944A (en) 1983-02-07 1985-01-29 Trutek Research, Inc. Inhalation therapy apparatus
US5743398A (en) * 1984-05-22 1998-04-28 Southpac Trust International, Inc. Floral wrapper utilizing a breathable packaging material
NZ209900A (en) 1984-10-16 1989-08-29 Univ Auckland Automatic inhaler
US4592348A (en) 1984-12-17 1986-06-03 Waters Iv William C Aerosol inhaler
FI88112C (fi) 1985-07-30 1993-04-13 Glaxo Group Ltd Anordning foer administrering av laekemedel till patienter
SE453566B (sv) 1986-03-07 1988-02-15 Draco Ab Anordning vid pulverinhalatorer
US4926852B1 (en) * 1986-06-23 1995-05-23 Univ Johns Hopkins Medication delivery system phase one
ES2051371T3 (es) 1988-10-04 1994-06-16 Univ Johns Hopkins Inhalador de aerosoles.
US5033655A (en) 1989-02-15 1991-07-23 Liquid Molding Systems Inc. Dispensing package for fluid products and the like
US4991745A (en) 1989-04-25 1991-02-12 Liquid Molding Systems, Inc. Dispensing valve with trampoline-like construction
WO1990013327A1 (en) 1989-04-28 1990-11-15 Riker Laboratories, Inc. Dry powder inhalation device
US4955371A (en) 1989-05-08 1990-09-11 Transtech Scientific, Inc. Disposable inhalation activated, aerosol device for pulmonary medicine
US5201308A (en) 1990-02-14 1993-04-13 Newhouse Michael T Powder inhaler
US5042467A (en) 1990-03-28 1991-08-27 Trudell Medical Medication inhaler with fitting having a sonic signalling device
DE4027391A1 (de) 1990-08-30 1992-03-12 Boehringer Ingelheim Kg Treibgasfreies inhalationsgeraet
DE4029183A1 (de) 1990-09-14 1992-03-19 Dieter Kuhn Durchflussregler
GB9021433D0 (en) 1990-10-02 1990-11-14 Atomic Energy Authority Uk Power inhaler
FR2667509B1 (fr) 1990-10-04 1995-08-25 Valois Inhalateur a poudre, dispositif de conditionnement de microdoses de poudre sous forme de bandes adaptees a etre utilisees dans un inhalateur a poudre, et procede de fabrication de ces bandes.
US5042472A (en) 1990-10-15 1991-08-27 Merck & Co., Inc. Powder inhaler device
GB9024760D0 (en) 1990-11-14 1991-01-02 Riker Laboratories Inc Inhalation device and medicament carrier
US5040527A (en) 1990-12-18 1991-08-20 Healthscan Products Inc. Metered dose inhalation unit with slide means
US5392768A (en) * 1991-03-05 1995-02-28 Aradigm Method and apparatus for releasing a controlled amount of aerosol medication over a selectable time interval
AU651882B2 (en) 1991-05-14 1994-08-04 Visiomed Group Limited Aerosol inhalation device
US6055980A (en) 1991-05-20 2000-05-02 Dura Pharmaceuticals, Inc. Dry powder inhaler
ES2141108T3 (es) 1991-07-02 2000-03-16 Inhale Inc Metodo y dispositivo para proporcionar medicamentos en aerosol.
US5337740A (en) 1991-08-01 1994-08-16 New England Pharmaceuticals, Inc. Inhalation devices
US5161524A (en) 1991-08-02 1992-11-10 Glaxo Inc. Dosage inhalator with air flow velocity regulating means
US6119688A (en) 1991-08-26 2000-09-19 3M Innovative Properties Company Powder dispenser
US5167506A (en) 1991-10-24 1992-12-01 Minnesota Mining And Manufacturing Company Inhalation device training system
US5396884A (en) * 1991-11-15 1995-03-14 Cimco, Inc. High flow rate humidifier with baffle plates
US5213236A (en) 1991-12-06 1993-05-25 Liquid Molding Systems, Inc. Dispensing valve for packaging
US5409144A (en) 1991-12-06 1995-04-25 Liquid Molding Systems Inc. Dispensing valve for packaging
DE4211475A1 (de) 1991-12-14 1993-06-17 Asta Medica Ag Pulverinhalator
US5320094A (en) 1992-01-10 1994-06-14 The Johns Hopkins University Method of administering insulin
EP0558879B1 (en) 1992-03-04 1997-05-14 Astra Aktiebolag Disposable inhaler
US5639441A (en) * 1992-03-06 1997-06-17 Board Of Regents Of University Of Colorado Methods for fine particle formation
US5785049A (en) 1994-09-21 1998-07-28 Inhale Therapeutic Systems Method and apparatus for dispersion of dry powder medicaments
US5284133A (en) 1992-07-23 1994-02-08 Armstrong Pharmaceuticals, Inc. Inhalation device with a dose-timer, an actuator mechanism, and patient compliance monitoring means
US5333106A (en) 1992-10-09 1994-07-26 Circadian, Inc. Apparatus and visual display method for training in the power use of aerosol pharmaceutical inhalers
DE4239402A1 (de) 1992-11-24 1994-05-26 Bayer Ag Pulverinhalator
US5888477A (en) * 1993-01-29 1999-03-30 Aradigm Corporation Use of monomeric insulin as a means for improving the bioavailability of inhaled insulin
US5672581A (en) 1993-01-29 1997-09-30 Aradigm Corporation Method of administration of insulin
US5507277A (en) * 1993-01-29 1996-04-16 Aradigm Corporation Lockout device for controlled release of drug from patient-activateddispenser
AU6167894A (en) 1993-01-29 1994-08-15 Miris Medical Corporation Intrapulmonary delivery of hormones
US5743250A (en) 1993-01-29 1998-04-28 Aradigm Corporation Insulin delivery enhanced by coached breathing
US5364838A (en) 1993-01-29 1994-11-15 Miris Medical Corporation Method of administration of insulin
US5873358A (en) 1993-01-29 1999-02-23 Aradigm Corporation Method of maintaining a diabetic patient's blood glucose level in a desired range
US5558085A (en) 1993-01-29 1996-09-24 Aradigm Corporation Intrapulmonary delivery of peptide drugs
FR2701399B1 (fr) 1993-02-16 1995-03-31 Valois Dispositif portatif de pulvérisation à actionnement déclenché par l'inhalation.
US5437271A (en) 1993-04-06 1995-08-01 Minnesota Mining And Manufacturing Company Deagglomerators for dry powder inhalers
US5349947A (en) * 1993-07-15 1994-09-27 Newhouse Michael T Dry powder inhaler and process that explosively discharges a dose of powder and gas from a soft plastic pillow
DK0714314T3 (da) 1993-08-18 1999-06-23 Fisons Plc Inhalator med åndedrætsregulering
US5655520A (en) 1993-08-23 1997-08-12 Howe; Harvey James Flexible valve for administering constant flow rates of medicine from a nebulizer
GB9326574D0 (en) 1993-12-31 1994-03-02 King S College London Dry power inhalers
US6102036A (en) 1994-04-12 2000-08-15 Smoke-Stop Breath activated inhaler
US5483954A (en) 1994-06-10 1996-01-16 Mecikalski; Mark B. Inhaler and medicated package
US5509404A (en) * 1994-07-11 1996-04-23 Aradigm Corporation Intrapulmonary drug delivery within therapeutically relevant inspiratory flow/volume values
US5653223A (en) 1994-09-08 1997-08-05 Pruitt; Michael D. Accurately controlled portable nebulizer
AU697676B2 (en) 1994-09-21 1998-10-15 Nektar Therapeutics Apparatus and methods for dispersing dry powder medicaments
US5993421A (en) * 1994-12-02 1999-11-30 Science Incorporated Medicament dispenser
US5552380A (en) * 1994-12-15 1996-09-03 International Flavors & Fragrances Inc. Perfume uses of phenyl alkanol derivatives
SE9404439D0 (sv) 1994-12-21 1994-12-21 Astra Ab Inhalation device
US5522380A (en) 1995-01-18 1996-06-04 Dwork; Paul Metered dose medication adaptor with improved incentive spirometer
US5568910A (en) * 1995-03-02 1996-10-29 Delmarva Laboratories, Inc. Anesthesia machine
US5513630A (en) 1995-03-08 1996-05-07 Century; Theodore J. Powder dispenser
CA2216443A1 (en) * 1995-03-31 1996-10-03 Aradigm Corporation Intrapulmonary delivery of hematopoietic drug
US5586550A (en) 1995-08-31 1996-12-24 Fluid Propulsion Technologies, Inc. Apparatus and methods for the delivery of therapeutic liquids to the respiratory system
US5921237A (en) 1995-04-24 1999-07-13 Dura Pharmaceuticals, Inc. Dry powder inhaler
US5622166A (en) 1995-04-24 1997-04-22 Dura Pharmaceuticals, Inc. Dry powder inhaler delivery system
US5654007A (en) 1995-06-07 1997-08-05 Inhale Therapeutic Systems Methods and system for processing dispersible fine powders
US5826571A (en) 1995-06-08 1998-10-27 Innovative Devices, Llc Device for use with metered dose inhalers (MDIS)
GB9513218D0 (en) 1995-06-29 1995-09-06 Fisons Plc Inhalation device and method
DE19523516C1 (de) 1995-06-30 1996-10-31 Asta Medica Ag Inhalator zum Verabreichen von Medikamenten aus Blisterpackungen
US5692496A (en) 1995-08-02 1997-12-02 Innovative Devices, Llc Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
US5988163A (en) 1995-08-02 1999-11-23 Innovative Devices Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of delivery of medicament
US5823183A (en) 1995-08-02 1998-10-20 Innovative Devices Dry powder medicament inhalator having an inhalation-activated flow diverting means for triggering delivery of medicament
US5603315A (en) * 1995-08-14 1997-02-18 Reliable Engineering Multiple mode oxygen delivery system
SE9503344D0 (sv) * 1995-09-27 1995-09-27 Astra Ab Inhalation device
CN1213974A (zh) 1996-01-03 1999-04-14 葛兰素集团有限公司 吸入器具
US5699789A (en) 1996-03-11 1997-12-23 Hendricks; Mark R. Dry powder inhaler
DE19613185A1 (de) 1996-04-02 1997-10-09 Pfeiffer Erich Gmbh & Co Kg Dosiereinrichtung für strömungsfähige Medien wie Pulver/Luft-Dispersionen
US5875776A (en) 1996-04-09 1999-03-02 Vivorx Pharmaceuticals, Inc. Dry powder inhaler
GB2312848B (en) 1996-04-26 1999-11-17 Bespak Plc Controlled flow inhalers
US5839430A (en) * 1996-04-26 1998-11-24 Cama; Joseph Combination inhaler and peak flow rate meter
US5826633A (en) 1996-04-26 1998-10-27 Inhale Therapeutic Systems Powder filling systems, apparatus and methods
CA2252814A1 (en) 1996-04-29 1997-11-06 Dura Pharmaceuticals, Inc. Methods of dry powder inhalation
AUPN973596A0 (en) * 1996-05-08 1996-05-30 Resmed Limited Control of delivery pressure in cpap treatment or assisted respiration
US5813401A (en) 1996-10-15 1998-09-29 Radcliff; Janet H. Nebulizer automatic control valve
SE9700422D0 (sv) 1997-02-07 1997-02-07 Astra Ab Single dose inhaler II
US6006747A (en) 1997-03-20 1999-12-28 Dura Pharmaceuticals, Inc. Dry powder inhaler
US6131571A (en) * 1997-04-30 2000-10-17 University Of Florida Ventilation apparatus and anesthesia delivery system
DE69829969T2 (de) * 1997-07-25 2006-03-09 Minnesota Innovative Technologies & Instruments Corp. (Miti), Lino Lakes Steuervorrichtung zum zuführen von zusätzlichem atmungssauerstoff
CA2212430A1 (en) 1997-08-07 1999-02-07 George Volgyesi Inhalation device
US5855202A (en) 1997-10-08 1999-01-05 Andrade; Joseph R. Aerosol holding chamber for a metered-dose inhaler
US6067984A (en) * 1997-10-14 2000-05-30 Piper; Samuel David Pulmonary modulator apparatus
US6032667A (en) * 1997-10-30 2000-03-07 Instrumentarium Corporation Variable orifice pulse valve
US6116238A (en) 1997-12-02 2000-09-12 Dura Pharmaceuticals, Inc. Dry powder inhaler
US6076523A (en) * 1998-01-15 2000-06-20 Nellcor Puritan Bennett Oxygen blending in a piston ventilator
US6142146A (en) 1998-06-12 2000-11-07 Microdose Technologies, Inc. Inhalation device

Also Published As

Publication number Publication date
US20050090798A1 (en) 2005-04-28
NO20004627L (no) 2000-10-11
DZ2744A1 (fr) 2004-12-28
JP4195191B2 (ja) 2008-12-10
PE20000346A1 (es) 2000-04-12
WO1999047196A1 (en) 1999-09-23
HRP20000608A2 (en) 2001-04-30
HUP0100848A1 (hu) 2001-06-28
HUP0100848A3 (en) 2005-04-28
EA003196B1 (ru) 2003-02-27
LV12586A (en) 2000-12-20
MA26033A1 (fr) 2004-04-01
LT2000095A (en) 2001-05-25
CO5060522A1 (es) 2001-07-30
EA200000823A1 (ru) 2001-02-26
CA2322045C (en) 2007-07-10
AP1342A (en) 2004-12-15
TR200002692T2 (tr) 2001-02-21
AR018161A1 (es) 2001-10-31
AU2980399A (en) 1999-10-11
EP1066074A1 (en) 2001-01-10
SI20413A (sl) 2001-06-30
CN1292714A (zh) 2001-04-25
BR9908771A (pt) 2000-12-12
NO20004627D0 (no) 2000-09-15
KR20010041924A (ko) 2001-05-25
YU56600A (sh) 2004-03-12
US20030183228A1 (en) 2003-10-02
HN1999000028A (es) 2001-06-19
AP2000001902A0 (en) 2000-09-30
HRP990081A2 (en) 2000-02-29
LT4818B (lt) 2001-07-25
CN1292714B (zh) 2012-08-01
JP2002506697A (ja) 2002-03-05
TWI228998B (en) 2005-03-11
RO121834B1 (ro) 2008-06-30
OA11529A (en) 2004-05-07
CA2322045A1 (en) 1999-09-23
US6655379B2 (en) 2003-12-02
BG104720A (en) 2001-04-30
IS5595A (is) 2000-08-22
TNSN99038A1 (fr) 2005-11-10
SA99200198B1 (ar) 2006-11-04
SK13632000A3 (sk) 2001-03-12
PL343276A1 (en) 2001-08-13
KR100620338B1 (ko) 2006-09-13
NZ506289A (en) 2004-12-24
GEP20043260B (en) 2004-06-25
EE200000546A (et) 2002-02-15
BG65091B1 (bg) 2007-02-28
AU750539B2 (en) 2002-07-18
PA8468901A1 (es) 2000-09-29
MY131803A (en) 2007-09-28
UY25432A1 (es) 1999-05-14
LV12586B (en) 2001-04-20
ID26237A (id) 2000-12-07

Similar Documents

Publication Publication Date Title
IL138153A0 (en) Methods and devices for delivering aerosolized active agents
HUP0104993A3 (en) Method and device for controlled delivery of active agents
HUP0103188A2 (hu) Vegyületek és készítmények hatóanyagok célbajuttatására
IL126318A0 (en) Compounds and compositions for delivering active agents
EP0979225A4 (en) CONNECTIONS AND PREPARATIONS FOR THE ADMINISTRATION OF ACTIVE AGENTS
HK1017995A1 (en) Compounds and compositions for delivering active agents.
EP1183068A4 (en) ENHANCED ACTIVE AGENT DELIVERY METHOD BY ELECTROPORATION
AP2001002366A0 (en) Systems and methods for aerosolizing pharmacetical formulations
HUP0100900A3 (en) Pharmaceutically active morpholinol and medicaments containing them
EP1246792A4 (en) COMPOUNDS AND COMPOSITIONS FOR ADMINISTERING ACTIVE INGREDIENTS
GB2365185A8 (en) Systems and methods for trading
IL211081A0 (en) Methods and devices for providing prolonged drug therapy
HUP0105057A3 (en) Dosing and delivering system
EP1123920A4 (en) HYDRAZINO-OXOACETAMIDE DERIVATIVES AND INSECTICIDES
HUP0200096A3 (en) Steroid sulfatase inhibitors and using the same
EP1075184A4 (en) ACTIVE VACCINATION COMPOSITIONS AND METHODS
GB9902812D0 (en) Composition for delivering pharmaceutically active agents
HUP9901162A3 (en) Compounds and compositions for delivering active agents
GB2329124B (en) Method of forming dose units of active agents
PT993831E (pt) Compostos e composições para administrar agentes activos
IL143011A0 (en) Compounds and compositions for delivering active agents
HK1037132A1 (en) Compound and composition for delivering active agents
HU9403836D0 (en) New active agents and pharmaceutical compositions for inhibiting malignus cell-proliferation
GB9814851D0 (en) Biologically and therapeautically active agents
ZA98805B (en) Active delivery device and related procedures

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees