PA8565401A1 - Metodo para preparar dispersiones solidas amorfas de farmacos secadas por pulverizacion utilizando inyectores a presion - Google Patents

Metodo para preparar dispersiones solidas amorfas de farmacos secadas por pulverizacion utilizando inyectores a presion

Info

Publication number
PA8565401A1
PA8565401A1 PA20038565401A PA8565401A PA8565401A1 PA 8565401 A1 PA8565401 A1 PA 8565401A1 PA 20038565401 A PA20038565401 A PA 20038565401A PA 8565401 A PA8565401 A PA 8565401A PA 8565401 A1 PA8565401 A1 PA 8565401A1
Authority
PA
Panama
Prior art keywords
amorphes
solid dispersions
spraying
preparing solid
pressure injectors
Prior art date
Application number
PA20038565401A
Other languages
English (en)
Inventor
Roderick Jack Ray
Daniel Elmont Dorby
Dana Marie Settell
Ronald Arthur Beyerinck
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27663274&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PA8565401(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of PA8565401A1 publication Critical patent/PA8565401A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

DISPERSIONES SOLIDAS AMORFAS HOMOGENEAS DE FARMACOS EN POLIMEROS MEJORADORES DE LA CONCENTRACION SE PREPARAN EN TAMANOS DE PARTICULA MAS GRANDES ADECUADOS CON MINIMO CONTENIDO DE FINOS, UTILIZANDO UN ATOMIZADOR Y CONDICIONES DE PROCEDIMIENTO CAPACES DE PRODUCIR GOTAS QUE TIENEN UN DIAMETRO MEDIO DE AL MENOS 50 MICRONES Y UN D10 DE AL MENOS 10 MICRONES.
PA20038565401A 2002-02-01 2003-02-03 Metodo para preparar dispersiones solidas amorfas de farmacos secadas por pulverizacion utilizando inyectores a presion PA8565401A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US35398602P 2002-02-01 2002-02-01

Publications (1)

Publication Number Publication Date
PA8565401A1 true PA8565401A1 (es) 2003-12-10

Family

ID=27663274

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20038565401A PA8565401A1 (es) 2002-02-01 2003-02-03 Metodo para preparar dispersiones solidas amorfas de farmacos secadas por pulverizacion utilizando inyectores a presion

Country Status (20)

Country Link
US (1) US7780988B2 (es)
EP (1) EP1469830A2 (es)
JP (1) JP2005523260A (es)
KR (1) KR100758045B1 (es)
CN (1) CN1787808A (es)
AR (1) AR038369A1 (es)
AU (1) AU2003239463B2 (es)
BR (1) BR0307515A (es)
CA (1) CA2474958A1 (es)
GT (1) GT200300024A (es)
MX (1) MXPA04007435A (es)
PA (1) PA8565401A1 (es)
PE (1) PE20030804A1 (es)
PL (1) PL371593A1 (es)
RS (1) RS67304A (es)
RU (1) RU2288703C2 (es)
TW (1) TW200404576A (es)
UY (1) UY27645A1 (es)
WO (1) WO2003063821A2 (es)
ZA (1) ZA200405971B (es)

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Also Published As

Publication number Publication date
US20030185893A1 (en) 2003-10-02
RU2004123639A (ru) 2005-04-20
GT200300024A (es) 2003-09-22
US7780988B2 (en) 2010-08-24
KR20040083491A (ko) 2004-10-02
PE20030804A1 (es) 2003-09-19
JP2005523260A (ja) 2005-08-04
WO2003063821A2 (en) 2003-08-07
WO2003063821A3 (en) 2003-11-13
RS67304A (en) 2006-10-27
ZA200405971B (en) 2006-05-31
UY27645A1 (es) 2003-09-30
RU2288703C2 (ru) 2006-12-10
AU2003239463B2 (en) 2007-10-18
KR100758045B1 (ko) 2007-09-11
BR0307515A (pt) 2004-12-07
PL371593A1 (en) 2005-06-27
MXPA04007435A (es) 2004-10-11
TW200404576A (en) 2004-04-01
AR038369A1 (es) 2005-01-12
CA2474958A1 (en) 2003-08-07
EP1469830A2 (en) 2004-10-27
CN1787808A (zh) 2006-06-14

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