UA41995C2 - Лікарська форма азитроміцину з контрольованим вивільненням ( варіанти ), спосіб її введення, спосіб її виготовлення і спосіб лікування інфекційних захворювань ссавців з її використанням ( варіанти ) - Google Patents

Лікарська форма азитроміцину з контрольованим вивільненням ( варіанти ), спосіб її введення, спосіб її виготовлення і спосіб лікування інфекційних захворювань ссавців з її використанням ( варіанти )

Info

Publication number
UA41995C2
UA41995C2 UA96114330A UA96114330A UA41995C2 UA 41995 C2 UA41995 C2 UA 41995C2 UA 96114330 A UA96114330 A UA 96114330A UA 96114330 A UA96114330 A UA 96114330A UA 41995 C2 UA41995 C2 UA 41995C2
Authority
UA
Ukraine
Prior art keywords
azithromycin
variants
dosage form
sustained release
release dosage
Prior art date
Application number
UA96114330A
Other languages
English (en)
Russian (ru)
Inventor
Уілльям Дж. Куратоло
Уильям Дж. Куратоло
Хілар Л. Фрідман
Хилар Л. Фридман
Річард В. Корсмейєр
Ричард В. Корсмейер
Мотт Стівен Р. Лє
Мотт Стивен Р. Ле
Original Assignee
Пфайзер Інк.
Пфайзер Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22900590&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA41995(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Пфайзер Інк., Пфайзер Инк. filed Critical Пфайзер Інк.
Publication of UA41995C2 publication Critical patent/UA41995C2/uk

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Detergent Compositions (AREA)

Abstract

Винахід відноситься до лікарської форми азитроміцину з контрольованим вивільненням. Лікарська форма з контрольованим вивільненням містить азитроміцин і фармацевтично прийнятний носій. Після проковтування лікарська форма вивільняє азитроміцин в шлунково-кишковий тракт ссавця з такою швидкістю, що загальна кількість вивільненого азитроміцину складає не більш ніж 4 мг азитроміцину на 1 кг ваги ссавця в перші 15 хв. після прийняття препарату, не більш ніж 10 мг азитроміцину на 1 кг ваги ссавця в першу годину після прийняття препарату, не більш ніж 20 мг азитроміцину на 1 кг ваги ссавця в перші 2 год. після прийняття препарату, не більш ніж 30 мг азитроміцину на 1 кг ваги ссавця в перші 4 год. після прийняття препарату, і не більш ніж 40 мг азитроміцину на 1 кг ваги ссавця в перші 6 год. після проковтування.
UA96114330A 1994-05-06 1995-04-13 Лікарська форма азитроміцину з контрольованим вивільненням ( варіанти ), спосіб її введення, спосіб її виготовлення і спосіб лікування інфекційних захворювань ссавців з її використанням ( варіанти ) UA41995C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23909494A 1994-05-06 1994-05-06
PCT/IB1995/000264 WO1995030422A1 (en) 1994-05-06 1995-04-13 Controlled-release dosage forms of azithromycin

Publications (1)

Publication Number Publication Date
UA41995C2 true UA41995C2 (uk) 2001-10-15

Family

ID=22900590

Family Applications (1)

Application Number Title Priority Date Filing Date
UA96114330A UA41995C2 (uk) 1994-05-06 1995-04-13 Лікарська форма азитроміцину з контрольованим вивільненням ( варіанти ), спосіб її введення, спосіб її виготовлення і спосіб лікування інфекційних захворювань ссавців з її використанням ( варіанти )

Country Status (42)

Country Link
US (2) US6068859A (uk)
EP (1) EP0758244B2 (uk)
JP (1) JP2977907B2 (uk)
KR (1) KR100232297B1 (uk)
CN (1) CN1096862C (uk)
AP (1) AP548A (uk)
AT (1) ATE209497T1 (uk)
AU (1) AU680356B2 (uk)
BG (1) BG63152B1 (uk)
BR (1) BR9501929A (uk)
CA (1) CA2189658C (uk)
CO (1) CO4290346A1 (uk)
CZ (1) CZ292360B6 (uk)
DE (1) DE69524214T3 (uk)
DK (1) DK0758244T4 (uk)
DZ (1) DZ1880A1 (uk)
ES (1) ES2163504T5 (uk)
FI (1) FI964452A0 (uk)
HR (1) HRP950277B1 (uk)
HU (1) HUT77530A (uk)
IL (3) IL113516A (uk)
IS (1) IS4282A (uk)
LV (1) LV11729B (uk)
MA (1) MA23537A1 (uk)
MX (1) MX9605419A (uk)
MY (1) MY113059A (uk)
NO (1) NO315453B1 (uk)
NZ (1) NZ283160A (uk)
OA (1) OA10320A (uk)
PE (1) PE4796A1 (uk)
PL (1) PL179910B1 (uk)
PT (1) PT758244E (uk)
RO (1) RO114740B1 (uk)
RU (1) RU2130311C1 (uk)
SI (1) SI9520049A (uk)
SK (1) SK282854B6 (uk)
TN (1) TNSN95051A1 (uk)
TW (1) TW420616B (uk)
UA (1) UA41995C2 (uk)
UY (1) UY23958A1 (uk)
WO (1) WO1995030422A1 (uk)
ZA (1) ZA953627B (uk)

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