PA8528401A1 - Derivados de quinolina y quinazolina - Google Patents

Derivados de quinolina y quinazolina

Info

Publication number
PA8528401A1
PA8528401A1 PA20018528401A PA8528401A PA8528401A1 PA 8528401 A1 PA8528401 A1 PA 8528401A1 PA 20018528401 A PA20018528401 A PA 20018528401A PA 8528401 A PA8528401 A PA 8528401A PA 8528401 A1 PA8528401 A1 PA 8528401A1
Authority
PA
Panama
Prior art keywords
quinazolina
quinolina
derivatives
pharmaceutical preparations
reivindication
Prior art date
Application number
PA20018528401A
Other languages
English (en)
Inventor
Volker Breu
Frank Dautzenberg
Philippe Guerry
Matthias Heinrich Nettekoven
Philippe Pflieger
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of PA8528401A1 publication Critical patent/PA8528401A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/78—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 2
    • C07D239/84—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Abstract

LOS COMPUESTOS DE FORMULA 1 ASI COMO LAS SALES UTILIZABLES FARMACEUTICAMENTE, SOLVATOS Y ESTERES DEL MISMO EN DONDE R1, R2, R3, R4, A1 Y A2 TIENEN EL SIGNIFICADO DADO EN LA REIVINDICACION 1, SE PUEDEN USAR EN FORMA DE PREPARACIONES FARMACEUTICAS PARA EL TRATAMIENTO O PREVENCION DE ARTRITIS, ENFERMEDADES CARDIOVASCULARES, DIABETES, INSUFICIENCIA RENAL, TRASTORNOS ALIMENTARIOS Y OBESIDAD.
PA20018528401A 2000-09-06 2001-09-04 Derivados de quinolina y quinazolina PA8528401A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00119262 2000-09-06

Publications (1)

Publication Number Publication Date
PA8528401A1 true PA8528401A1 (es) 2002-09-30

Family

ID=8169763

Family Applications (1)

Application Number Title Priority Date Filing Date
PA20018528401A PA8528401A1 (es) 2000-09-06 2001-09-04 Derivados de quinolina y quinazolina

Country Status (16)

Country Link
US (2) US6900226B2 (es)
EP (1) EP1318981A2 (es)
JP (1) JP2004508357A (es)
KR (1) KR100621272B1 (es)
CN (1) CN1274676C (es)
AR (1) AR030596A1 (es)
AU (2) AU2002210474B2 (es)
BR (1) BR0113710A (es)
CA (1) CA2420703A1 (es)
GT (1) GT200100183A (es)
MX (1) MXPA03001928A (es)
PA (1) PA8528401A1 (es)
PE (1) PE20020485A1 (es)
UY (1) UY26926A1 (es)
WO (1) WO2002020488A2 (es)
ZA (1) ZA200301719B (es)

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Also Published As

Publication number Publication date
CA2420703A1 (en) 2002-03-14
WO2002020488A2 (en) 2002-03-14
CN1444563A (zh) 2003-09-24
US20020052356A1 (en) 2002-05-02
KR100621272B1 (ko) 2006-09-13
US20050176698A1 (en) 2005-08-11
UY26926A1 (es) 2002-03-22
AR030596A1 (es) 2003-08-27
KR20030027110A (ko) 2003-04-03
ZA200301719B (en) 2004-06-22
GT200100183A (es) 2002-05-23
US7265125B2 (en) 2007-09-04
US6900226B2 (en) 2005-05-31
AU1047402A (en) 2002-03-22
AU2002210474B2 (en) 2006-11-02
PE20020485A1 (es) 2002-06-14
BR0113710A (pt) 2003-06-03
CN1274676C (zh) 2006-09-13
JP2004508357A (ja) 2004-03-18
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MXPA03001928A (es) 2003-06-19
WO2002020488A3 (en) 2002-05-16

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