OA12166A - Calcium dicarboxylate ethers, methods of making same, and treatment of vascular disease and diabetestherewith. - Google Patents

Calcium dicarboxylate ethers, methods of making same, and treatment of vascular disease and diabetestherewith. Download PDF

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Publication number
OA12166A
OA12166A OA1200200226A OA1200200226A OA12166A OA 12166 A OA12166 A OA 12166A OA 1200200226 A OA1200200226 A OA 1200200226A OA 1200200226 A OA1200200226 A OA 1200200226A OA 12166 A OA12166 A OA 12166A
Authority
OA
OAPI
Prior art keywords
sait
compound
carboxy
methyl
hexyloxy
Prior art date
Application number
OA1200200226A
Other languages
English (en)
Inventor
Howard Yoshihisa Ando
Donald Eugene Butler
Gary Jay Dozeman
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of OA12166A publication Critical patent/OA12166A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/125—Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235—Saturated compounds containing more than one carboxyl group
    • C07C59/305—Saturated compounds containing more than one carboxyl group containing ether groups, groups, groups, or groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
OA1200200226A 2000-01-25 2001-01-11 Calcium dicarboxylate ethers, methods of making same, and treatment of vascular disease and diabetestherewith. OA12166A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17782300P 2000-01-25 2000-01-25

Publications (1)

Publication Number Publication Date
OA12166A true OA12166A (en) 2003-11-07

Family

ID=22650106

Family Applications (1)

Application Number Title Priority Date Filing Date
OA1200200226A OA12166A (en) 2000-01-25 2001-01-11 Calcium dicarboxylate ethers, methods of making same, and treatment of vascular disease and diabetestherewith.

Country Status (39)

Country Link
EP (1) EP1259474B1 (sr)
JP (1) JP4750995B2 (sr)
KR (1) KR20020073182A (sr)
CN (1) CN1395555A (sr)
AP (1) AP2002002587A0 (sr)
AR (1) AR029436A1 (sr)
AT (1) ATE431326T1 (sr)
AU (1) AU2214001A (sr)
BG (1) BG106851A (sr)
BR (1) BR0107763A (sr)
CA (1) CA2397960C (sr)
CO (1) CO5261537A1 (sr)
CZ (1) CZ20022474A3 (sr)
DE (1) DE60138686D1 (sr)
DK (1) DK1259474T3 (sr)
DZ (1) DZ3239A1 (sr)
EA (1) EA004862B1 (sr)
EE (1) EE200200404A (sr)
ES (1) ES2324281T3 (sr)
GE (1) GEP20053428B (sr)
GT (1) GT200100015A (sr)
HN (1) HN2001000011A (sr)
HU (1) HUP0204422A3 (sr)
IL (1) IL150541A0 (sr)
IS (1) IS6442A (sr)
MA (1) MA26867A1 (sr)
MX (1) MXPA02007223A (sr)
NO (1) NO20023526L (sr)
NZ (1) NZ519550A (sr)
OA (1) OA12166A (sr)
PA (1) PA8510601A1 (sr)
PE (1) PE20011064A1 (sr)
PL (1) PL357076A1 (sr)
SK (1) SK10622002A3 (sr)
SV (1) SV2002000290A (sr)
TN (1) TNSN01013A1 (sr)
UY (1) UY26550A1 (sr)
WO (1) WO2001055078A1 (sr)
ZA (1) ZA200205880B (sr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1481962A1 (en) * 1997-12-12 2004-12-01 Warner-Lambert Company LLC New cholesterolemia-lowering carboxyalkylether compound
PL375742A1 (en) * 2002-08-22 2005-12-12 Warner-Lambert Company Llc Method of treating osteoarthritis
US7816405B2 (en) 2005-04-19 2010-10-19 Eisai R&D Management Co., Ltd. Calcium bis [(2S)-3-[3-[(2S)-3-(4-chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl ]-2-isopropoxypropionate] and intermediate thereof
EP1873141A4 (en) * 2005-04-19 2010-09-22 Eisai R&D Man Co Ltd CALCIUM-BIS [2S] -3- [3- (2S) -3- (4-CHLORO-2-CYANOPHENOXY) -2-FLUORO-PROPOXYPHENYL] -2-ISOPROPOXYPROPIONATE] AND INTERMEDIATE PRODUCTS THEREOF
AU2015346037A1 (en) * 2014-11-14 2017-07-06 Gemphire Therapeutics Inc. Processes and intermediates for preparing alpha,omega-dicarboxylic acid-terminated dialkane ethers
CN110996928A (zh) * 2017-04-18 2020-04-10 燿石治疗公司 吉卡宾、其药学上可接受的盐、其组合物和其使用方法
US20200253877A1 (en) * 2018-10-18 2020-08-13 Neurobo Pharmaceuticals, Inc. Gemcabene, pharmaceutically acceptable salts thereof, compositions thereof and methods of use therefor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648387A (en) 1995-03-24 1997-07-15 Warner-Lambert Company Carboxyalkylethers, formulations, and treatment of vascular diseases
NZ503982A (en) 1997-12-12 2002-03-28 Warner Lambert Co Statin-carboxyalkylether combinations useful for treating vascular disorders and diabetes mellitus

Also Published As

Publication number Publication date
PE20011064A1 (es) 2001-10-22
IS6442A (is) 2002-06-25
NO20023526L (no) 2002-08-27
SK10622002A3 (sk) 2003-07-01
ZA200205880B (en) 2003-07-23
CA2397960A1 (en) 2001-08-02
DE60138686D1 (de) 2009-06-25
MA26867A1 (fr) 2004-12-20
KR20020073182A (ko) 2002-09-19
EA200200641A1 (ru) 2002-12-26
AP2002002587A0 (en) 2002-09-30
MXPA02007223A (es) 2002-11-29
CA2397960C (en) 2008-09-09
JP2003520835A (ja) 2003-07-08
CN1395555A (zh) 2003-02-05
AU2214001A (en) 2001-08-07
EA004862B1 (ru) 2004-08-26
NO20023526D0 (no) 2002-07-24
PA8510601A1 (es) 2002-08-26
EP1259474A1 (en) 2002-11-27
HUP0204422A2 (en) 2003-05-28
EE200200404A (et) 2003-10-15
DZ3239A1 (fr) 2001-08-02
BG106851A (en) 2003-01-31
CZ20022474A3 (cs) 2003-06-18
WO2001055078A1 (en) 2001-08-02
GT200100015A (es) 2001-10-19
AR029436A1 (es) 2003-06-25
HUP0204422A3 (en) 2003-08-28
JP4750995B2 (ja) 2011-08-17
NZ519550A (en) 2003-11-28
ATE431326T1 (de) 2009-05-15
UY26550A1 (es) 2001-08-27
EP1259474B1 (en) 2009-05-13
ES2324281T3 (es) 2009-08-04
IL150541A0 (en) 2003-02-12
BR0107763A (pt) 2002-11-12
DK1259474T3 (da) 2009-07-20
CO5261537A1 (es) 2003-03-31
TNSN01013A1 (fr) 2005-11-10
SV2002000290A (es) 2002-07-16
PL357076A1 (en) 2004-07-12
GEP20053428B (en) 2005-01-25
HN2001000011A (es) 2001-06-13

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