TNSN01013A1 - Ether-dicarboxylates de calcium, procedes pour leur preparation et traitement de maladies vasculaires et du diabete avec ces composes - Google Patents

Ether-dicarboxylates de calcium, procedes pour leur preparation et traitement de maladies vasculaires et du diabete avec ces composes

Info

Publication number
TNSN01013A1
TNSN01013A1 TNTNSN01013A TNSN01013A TNSN01013A1 TN SN01013 A1 TNSN01013 A1 TN SN01013A1 TN TNSN01013 A TNTNSN01013 A TN TNSN01013A TN SN01013 A TNSN01013 A TN SN01013A TN SN01013 A1 TNSN01013 A1 TN SN01013A1
Authority
TN
Tunisia
Prior art keywords
preparation
treatment
dicarboxylates
diabetes
methods
Prior art date
Application number
TNTNSN01013A
Other languages
English (en)
Inventor
Yoshibisa Ando Howard
Eugene Butler Donald
Jay Dozeman Gary
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of TNSN01013A1 publication Critical patent/TNSN01013A1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/125Saturated compounds having only one carboxyl group and containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/235Saturated compounds containing more than one carboxyl group
    • C07C59/305Saturated compounds containing more than one carboxyl group containing ether groups, groups, groups, or groups
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/14Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

L’INVENTION CONCERNE DES PRODUITS DE SOLVATATION AVEC DES ALCOOLS ET L’EAU DU SEL MONOCALCIQUE D’ACIDE 6-(5- CARBOXY-5-METHYL-HEXYLOXY)-2,2-DIMETHYL-HEXANOIQUE, QUI SONT CRISTALLINS ET QUI REPONDENT A LA FORMULE : DANS LAQUELLE R1 REPRESENTE H OU UN GROUPE ALKYLE INFERIEUR ET X A UNE VALEUR DE 0 A 10. ELLE CONCERNE EGALEMENT UN PROCEDE POUR LEUR PREPARATION ET DES COMPOSITIONS LES CONTENANT. APPLICATION : UTILISATION DE CES COMPOSES ET COMPOSITIONS POUR LE TRAITEMENT DE LA DYSLIPIDEMIE.
TNTNSN01013A 2000-01-25 2001-01-24 Ether-dicarboxylates de calcium, procedes pour leur preparation et traitement de maladies vasculaires et du diabete avec ces composes TNSN01013A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17782300P 2000-01-25 2000-01-25

Publications (1)

Publication Number Publication Date
TNSN01013A1 true TNSN01013A1 (fr) 2005-11-10

Family

ID=22650106

Family Applications (1)

Application Number Title Priority Date Filing Date
TNTNSN01013A TNSN01013A1 (fr) 2000-01-25 2001-01-24 Ether-dicarboxylates de calcium, procedes pour leur preparation et traitement de maladies vasculaires et du diabete avec ces composes

Country Status (39)

Country Link
EP (1) EP1259474B1 (fr)
JP (1) JP4750995B2 (fr)
KR (1) KR20020073182A (fr)
CN (1) CN1395555A (fr)
AP (1) AP2002002587A0 (fr)
AR (1) AR029436A1 (fr)
AT (1) ATE431326T1 (fr)
AU (1) AU2214001A (fr)
BG (1) BG106851A (fr)
BR (1) BR0107763A (fr)
CA (1) CA2397960C (fr)
CO (1) CO5261537A1 (fr)
CZ (1) CZ20022474A3 (fr)
DE (1) DE60138686D1 (fr)
DK (1) DK1259474T3 (fr)
DZ (1) DZ3239A1 (fr)
EA (1) EA004862B1 (fr)
EE (1) EE200200404A (fr)
ES (1) ES2324281T3 (fr)
GE (1) GEP20053428B (fr)
GT (1) GT200100015A (fr)
HN (1) HN2001000011A (fr)
HU (1) HUP0204422A3 (fr)
IL (1) IL150541A0 (fr)
IS (1) IS6442A (fr)
MA (1) MA26867A1 (fr)
MX (1) MXPA02007223A (fr)
NO (1) NO20023526L (fr)
NZ (1) NZ519550A (fr)
OA (1) OA12166A (fr)
PA (1) PA8510601A1 (fr)
PE (1) PE20011064A1 (fr)
PL (1) PL357076A1 (fr)
SK (1) SK10622002A3 (fr)
SV (1) SV2002000290A (fr)
TN (1) TNSN01013A1 (fr)
UY (1) UY26550A1 (fr)
WO (1) WO2001055078A1 (fr)
ZA (1) ZA200205880B (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1481962A1 (fr) * 1997-12-12 2004-12-01 Warner-Lambert Company LLC Nouveau carboxyéthylether reduisant la cholesterolémie
PL375742A1 (en) * 2002-08-22 2005-12-12 Warner-Lambert Company Llc Method of treating osteoarthritis
US7816405B2 (en) 2005-04-19 2010-10-19 Eisai R&D Management Co., Ltd. Calcium bis [(2S)-3-[3-[(2S)-3-(4-chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl ]-2-isopropoxypropionate] and intermediate thereof
EP1873141A4 (fr) * 2005-04-19 2010-09-22 Eisai R&D Man Co Ltd Bis[(2s)-3-[3-](2s)-3-(4-chloro-2-cyanophenoxy)-2-fluoropropoxy]phenyl]-2-isopropoxypropionate]de calcium et intermediaire de celui-ci
AU2015346037A1 (en) * 2014-11-14 2017-07-06 Gemphire Therapeutics Inc. Processes and intermediates for preparing alpha,omega-dicarboxylic acid-terminated dialkane ethers
CN110996928A (zh) * 2017-04-18 2020-04-10 燿石治疗公司 吉卡宾、其药学上可接受的盐、其组合物和其使用方法
US20200253877A1 (en) * 2018-10-18 2020-08-13 Neurobo Pharmaceuticals, Inc. Gemcabene, pharmaceutically acceptable salts thereof, compositions thereof and methods of use therefor

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5648387A (en) 1995-03-24 1997-07-15 Warner-Lambert Company Carboxyalkylethers, formulations, and treatment of vascular diseases
NZ503982A (en) 1997-12-12 2002-03-28 Warner Lambert Co Statin-carboxyalkylether combinations useful for treating vascular disorders and diabetes mellitus

Also Published As

Publication number Publication date
PE20011064A1 (es) 2001-10-22
IS6442A (is) 2002-06-25
NO20023526L (no) 2002-08-27
SK10622002A3 (sk) 2003-07-01
ZA200205880B (en) 2003-07-23
OA12166A (en) 2003-11-07
CA2397960A1 (fr) 2001-08-02
DE60138686D1 (de) 2009-06-25
MA26867A1 (fr) 2004-12-20
KR20020073182A (ko) 2002-09-19
EA200200641A1 (ru) 2002-12-26
AP2002002587A0 (en) 2002-09-30
MXPA02007223A (es) 2002-11-29
CA2397960C (fr) 2008-09-09
JP2003520835A (ja) 2003-07-08
CN1395555A (zh) 2003-02-05
AU2214001A (en) 2001-08-07
EA004862B1 (ru) 2004-08-26
NO20023526D0 (no) 2002-07-24
PA8510601A1 (es) 2002-08-26
EP1259474A1 (fr) 2002-11-27
HUP0204422A2 (en) 2003-05-28
EE200200404A (et) 2003-10-15
DZ3239A1 (fr) 2001-08-02
BG106851A (en) 2003-01-31
CZ20022474A3 (cs) 2003-06-18
WO2001055078A1 (fr) 2001-08-02
GT200100015A (es) 2001-10-19
AR029436A1 (es) 2003-06-25
HUP0204422A3 (en) 2003-08-28
JP4750995B2 (ja) 2011-08-17
NZ519550A (en) 2003-11-28
ATE431326T1 (de) 2009-05-15
UY26550A1 (es) 2001-08-27
EP1259474B1 (fr) 2009-05-13
ES2324281T3 (es) 2009-08-04
IL150541A0 (en) 2003-02-12
BR0107763A (pt) 2002-11-12
DK1259474T3 (da) 2009-07-20
CO5261537A1 (es) 2003-03-31
SV2002000290A (es) 2002-07-16
PL357076A1 (en) 2004-07-12
GEP20053428B (en) 2005-01-25
HN2001000011A (es) 2001-06-13

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