NZ185909A - 1,5-dusubstituted hydantois (or 2-thiohydantoins)and pharmaxeutical compositions - Google Patents

1,5-dusubstituted hydantois (or 2-thiohydantoins)and pharmaxeutical compositions

Info

Publication number
NZ185909A
NZ185909A NZ185909A NZ18590977A NZ185909A NZ 185909 A NZ185909 A NZ 185909A NZ 185909 A NZ185909 A NZ 185909A NZ 18590977 A NZ18590977 A NZ 18590977A NZ 185909 A NZ185909 A NZ 185909A
Authority
NZ
New Zealand
Prior art keywords
pharmaxeutical
hydantois
dusubstituted
thiohydantoins
compositions
Prior art date
Application number
NZ185909A
Other languages
English (en)
Inventor
G Wootton
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB52955/76A external-priority patent/GB1598662A/en
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of NZ185909A publication Critical patent/NZ185909A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72Two oxygen atoms, e.g. hydantoin
    • C07D233/76Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C273/00Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C273/18Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
    • C07C273/1809Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety
    • C07C273/1818Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas with formation of the N-C(O)-N moiety from -N=C=O and XNR'R"
    • C07C273/1827X being H
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/86Oxygen and sulfur atoms, e.g. thiohydantoin

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NZ185909A 1976-12-18 1977-12-08 1,5-dusubstituted hydantois (or 2-thiohydantoins)and pharmaxeutical compositions NZ185909A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB52955/76A GB1598662A (en) 1976-12-18 1976-12-18 10,12-diazoprostaglandins
GB3036977 1977-07-20

Publications (1)

Publication Number Publication Date
NZ185909A true NZ185909A (en) 1980-11-14

Family

ID=26260409

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ185909A NZ185909A (en) 1976-12-18 1977-12-08 1,5-dusubstituted hydantois (or 2-thiohydantoins)and pharmaxeutical compositions

Country Status (15)

Country Link
JP (1) JPS5382779A (xx)
AT (1) AT368498B (xx)
AU (1) AU514523B2 (xx)
CH (1) CH639076A5 (xx)
DE (1) DE2755771A1 (xx)
DK (1) DK551777A (xx)
ES (1) ES465176A1 (xx)
FI (1) FI773812A (xx)
FR (1) FR2374309A1 (xx)
IL (1) IL53559A0 (xx)
NL (1) NL7713971A (xx)
NO (1) NO774348L (xx)
NZ (1) NZ185909A (xx)
PH (1) PH14398A (xx)
SE (1) SE7714373L (xx)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1602188A (en) 1977-12-01 1981-11-11 Wellcome Found Hydantoin derivatives
DK543178A (da) * 1977-12-01 1979-06-02 Wellcome Found Thiodydantoinderivater
EP0003410B1 (en) * 1978-01-23 1982-10-06 Beecham Group Plc Hydantoins and thiohydantoins, method for their preparation and pharmaceutical compositions containing them
EP0004723A1 (en) * 1978-03-30 1979-10-17 Beecham Group Plc Deoxyhydantoins, processes for their preparation and pharmaceutical compositions containing them
EP0006352A1 (en) * 1978-06-15 1980-01-09 Beecham Group Plc Hydantoins and thiohydantoins, process for their preparation and pharmaceutical compositions containing them
IL57504A0 (en) * 1978-06-15 1979-10-31 Beecham Group Ltd Prostagandin analogues,their preparation and pharmaceutical compositions containing
AU4778279A (en) * 1978-06-15 1979-12-20 Beecham Group Limited Prostaglandin analogues
US4294972A (en) * 1978-06-15 1981-10-13 Beecham Group Limited 1,2-Disubstituted oxo triazolidine
GB2050371A (en) * 1979-05-09 1981-01-07 Wellcome Found Optically active hydantoin derivatives and pharmaceutical formulations containing them

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2323193A1 (de) 1972-05-10 1973-11-22 Du Pont Pyrazolidinone
FR2258376A1 (en) 1974-01-21 1975-08-18 Aries Robert 10-Aza prostaglandins - for treatment of blood pressure and gastro-intestinal disorders and in prepn for confinement
GB1524818A (en) 1974-11-29 1978-09-13 Beecham Group Ltd 12-azaprostaglandins

Also Published As

Publication number Publication date
AT368498B (de) 1982-10-11
DE2755771A1 (de) 1978-06-29
JPS5382779A (en) 1978-07-21
NO774348L (no) 1978-06-20
ES465176A1 (es) 1979-01-01
ATA893777A (de) 1982-02-15
CH639076A5 (en) 1983-10-31
NL7713971A (nl) 1978-06-20
FR2374309B1 (xx) 1980-05-16
FI773812A (fi) 1978-06-19
IL53559A0 (en) 1978-03-10
AU3161377A (en) 1979-06-21
SE7714373L (sv) 1978-06-19
DK551777A (da) 1978-06-19
AU514523B2 (en) 1981-02-12
PH14398A (en) 1981-06-25
FR2374309A1 (fr) 1978-07-13

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