NO985300D0 - FremgangsmÕte for spalting av racemisk ketamin - Google Patents

FremgangsmÕte for spalting av racemisk ketamin

Info

Publication number
NO985300D0
NO985300D0 NO985300A NO985300A NO985300D0 NO 985300 D0 NO985300 D0 NO 985300D0 NO 985300 A NO985300 A NO 985300A NO 985300 A NO985300 A NO 985300A NO 985300 D0 NO985300 D0 NO 985300D0
Authority
NO
Norway
Prior art keywords
pct
cleavage
racemic ketamine
date nov
ketamine
Prior art date
Application number
NO985300A
Other languages
English (en)
Other versions
NO985300L (no
NO311565B1 (no
Inventor
Klaus Steiner
Stefan Gangkofner
Jean-Marie Grunenwald
Original Assignee
Uetikon Chemie Gmbh
Goedecke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uetikon Chemie Gmbh, Goedecke Ag filed Critical Uetikon Chemie Gmbh
Publication of NO985300L publication Critical patent/NO985300L/no
Publication of NO985300D0 publication Critical patent/NO985300D0/no
Publication of NO311565B1 publication Critical patent/NO311565B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/20Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C221/00Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pyrrole Compounds (AREA)
NO19985300A 1996-05-15 1998-11-13 Fremgangsmåte for spalting av racemisk ketamin NO311565B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19619665A DE19619665C2 (de) 1996-05-15 1996-05-15 Racemattrennung von Ketamin
PCT/EP1997/002360 WO1997043244A1 (de) 1996-05-15 1997-05-07 Racemattrennung von ketamin

Publications (3)

Publication Number Publication Date
NO985300L NO985300L (no) 1998-11-13
NO985300D0 true NO985300D0 (no) 1998-11-13
NO311565B1 NO311565B1 (no) 2001-12-10

Family

ID=7794445

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19985300A NO311565B1 (no) 1996-05-15 1998-11-13 Fremgangsmåte for spalting av racemisk ketamin

Country Status (20)

Country Link
US (1) US6040479A (no)
EP (1) EP0918744B1 (no)
JP (1) JP4151988B2 (no)
AT (1) ATE272606T1 (no)
AU (1) AU727528B2 (no)
CA (1) CA2253575C (no)
CZ (1) CZ293546B6 (no)
DE (2) DE19619665C2 (no)
DK (1) DK0918744T3 (no)
EE (1) EE03436B1 (no)
ES (1) ES2224247T3 (no)
HU (1) HU225773B1 (no)
IL (1) IL127026A (no)
NO (1) NO311565B1 (no)
PL (1) PL187625B1 (no)
PT (1) PT918744E (no)
SK (1) SK282699B6 (no)
TR (1) TR199802317T2 (no)
WO (1) WO1997043244A1 (no)
ZA (1) ZA974216B (no)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0002693B8 (pt) * 2000-06-19 2021-05-25 Cristalia Produtos Quim Farmaceuticos Ltda processo de obtenção dos enantiômeros da cetamina e seus sais farmaceuticamente aceitáveis
SG11201507347QA (en) 2013-03-15 2015-10-29 Janssen Pharmaceutica Nv Pharmaceutical composition of s-ketamine hydrochloride
EP3964203A1 (en) 2013-09-13 2022-03-09 National University Corporation Chiba University Application of r-ketamine and salt thereof as pharmaceuticals
US10098854B2 (en) 2014-08-13 2018-10-16 Janssen Pharmaceutica Nv Method for the treatment of depression
EP3725307A1 (en) 2014-09-15 2020-10-21 Janssen Pharmaceutica NV Val66met (snp rs6265) genotype specific dosing regimens and methods for the treatment of depression
US20160332962A1 (en) * 2015-05-13 2016-11-17 Janssen Pharmaceutica Nv (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine
CN110167541A (zh) 2016-10-27 2019-08-23 国立大学法人千叶大学 (s)-去甲***及其盐作为药物的应用
US20200009081A1 (en) 2017-09-13 2020-01-09 Janssen Pharmaceutica N.V. Delivery Of Esketamine For The Treatment Of Depression
TW201919595A (zh) 2017-09-27 2019-06-01 國立大學法人千葉大學 作為神經變性疾病或認知機能障礙之預防或治療劑之r-***及其衍生物
MX2020006650A (es) 2017-12-22 2020-11-06 Janssen Pharmaceuticals Inc Esketamina para el tratamiento de la depresión.
CN111936127A (zh) 2018-02-15 2020-11-13 国立大学法人千叶大学 炎症性疾病或骨病的预防或治疗剂及医药组合物
WO2019213551A1 (en) 2018-05-04 2019-11-07 Perception Neuroscience, Inc. Methods of treating substance abuse
JP7483630B2 (ja) 2018-12-27 2024-05-15 国立大学法人千葉大学 神経発達障害の予防または治療剤としてのr-ケタミンおよびその誘導体
MX2021010683A (es) 2019-03-05 2021-12-10 Janssen Pharmaceuticals Inc Esketamina para el tratamiento de la depresión.
US20220220062A1 (en) * 2019-04-16 2022-07-14 Janssen Pharmaceutica Nv Synthetic methods of preparing esketamine
CN112125816A (zh) * 2020-03-17 2020-12-25 国药集团工业有限公司 一种***、其衍生物或其盐的消旋化方法
CN112409195A (zh) * 2020-03-17 2021-02-26 国药集团工业有限公司 一种(s)-***盐酸盐的制备方法及其中间体、其晶型

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH535201A (de) * 1969-12-19 1973-03-31 Bristol Myers Co Verfahren zur Spaltung von racemischen 2-(o-Chlorphenyl)-2-methylaminocyclohexanon in die optisch-aktiven Isomeren

Also Published As

Publication number Publication date
EE03436B1 (et) 2001-06-15
EP0918744A1 (de) 1999-06-02
CZ293546B6 (cs) 2004-06-16
HU225773B1 (en) 2007-08-28
DK0918744T3 (da) 2004-12-06
JP2000510135A (ja) 2000-08-08
PT918744E (pt) 2004-10-29
TR199802317T2 (xx) 1999-02-22
NO985300L (no) 1998-11-13
NO311565B1 (no) 2001-12-10
DE19619665C2 (de) 2001-03-08
EE9800394A (et) 1999-06-15
DE19619665A1 (de) 1997-11-20
ES2224247T3 (es) 2005-03-01
AU2894397A (en) 1997-12-05
HUP9903085A3 (en) 2000-05-29
JP4151988B2 (ja) 2008-09-17
IL127026A (en) 2004-02-19
ATE272606T1 (de) 2004-08-15
SK152998A3 (en) 1999-07-12
ZA974216B (en) 1997-12-10
EP0918744B1 (de) 2004-08-04
CA2253575A1 (en) 1997-11-20
AU727528B2 (en) 2000-12-14
PL187625B1 (pl) 2004-08-31
WO1997043244A1 (de) 1997-11-20
US6040479A (en) 2000-03-21
PL329743A1 (en) 1999-04-12
IL127026A0 (en) 1999-09-22
DE59711834D1 (de) 2004-09-09
SK282699B6 (sk) 2002-11-06
CA2253575C (en) 2005-11-29
CZ355898A3 (cs) 1999-04-14
HUP9903085A1 (hu) 2000-04-28

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