NO982072L - Amidin- og isotioureaderivater som inhibitorer av nitrogenoksydsyntase - Google Patents

Amidin- og isotioureaderivater som inhibitorer av nitrogenoksydsyntase

Info

Publication number: NO982072L
Authority: NO; Norway
Prior art keywords: amidine; inhibitors; nitric oxide; oxide synthase; isothiourea derivatives
Prior art date: 1995-11-07

Application number

NO982072A

Other languages

English (en)

Norwegian (no)

Other versions

NO982072D0 (no

Inventor

James Macdonald

James Matz

William Shakespeare

Original Assignee

Astra Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-11-07

Filing date

1998-05-06

Publication date

1998-07-03

1996-01-25 Priority claimed from SE9600275A external-priority patent/SE9600275D0/xx

1996-09-11 Priority claimed from SE9603300A external-priority patent/SE9603300D0/xx

1996-09-11 Priority claimed from SE9603301A external-priority patent/SE9603301D0/xx

1998-05-06 Application filed by Astra Ab filed Critical Astra Ab

1998-05-06 Publication of NO982072D0 publication Critical patent/NO982072D0/no

1998-07-03 Publication of NO982072L publication Critical patent/NO982072L/no

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

NO982072A 1995-11-07 1998-05-06 Amidin- og isotioureaderivater som inhibitorer av nitrogenoksydsyntase NO982072L (no)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
US627695P	1995-11-07	1995-11-07
US625395P	1995-11-07	1995-11-07
SE9600275A SE9600275D0 (sv)	1996-01-25	1996-01-25	Compounds
SE9603300A SE9603300D0 (sv)	1996-09-11	1996-09-11	Compounds
SE9603301A SE9603301D0 (sv)	1996-09-11	1996-09-11	Compounds and compositions
PCT/SE1996/001425 WO1997017344A1 (en)	1995-11-07	1996-11-06	Amidine and isothiourea derivatives as inhibitors of nitric oxide synthase

Publications (2)

Publication Number	Publication Date
NO982072D0 NO982072D0 (no)	1998-05-06
NO982072L true NO982072L (no)	1998-07-03

Family

ID=27532790

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO982072A NO982072L (no)	1995-11-07	1998-05-06	Amidin- og isotioureaderivater som inhibitorer av nitrogenoksydsyntase

Country Status (24)

Country	Link
EP (1)	EP0861250B1 (ja)
JP (1)	JP2000500132A (ja)
KR (1)	KR19990067349A (ja)
AT (1)	ATE213241T1 (ja)
AU (1)	AU701329B2 (ja)
BR (1)	BR9611276A (ja)
CA (1)	CA2235301A1 (ja)
CZ (1)	CZ139298A3 (ja)
DE (1)	DE69619259T2 (ja)
DK (1)	DK0861250T3 (ja)
EE (1)	EE9800141A (ja)
ES (1)	ES2171743T3 (ja)
HU (1)	HUP9900142A3 (ja)
IL (1)	IL124296A0 (ja)
IS (1)	IS4725A (ja)
NO (1)	NO982072L (ja)
NZ (1)	NZ322227A (ja)
PL (1)	PL326554A1 (ja)
PT (1)	PT861250E (ja)
SI (1)	SI0861250T1 (ja)
SK (1)	SK61098A3 (ja)
TR (1)	TR199800813T2 (ja)
TW (1)	TW458978B (ja)
WO (1)	WO1997017344A1 (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1998016526A1 (en) *	1996-10-16	1998-04-23	Glaxo Group Limited	Tetrahydro-6h-pyrazino[1,2-b]isoquinoline 1,4-diones as apoprotein b-100 inhibitors
SE9701681D0 (sv)	1997-05-05	1997-05-05	Astra Ab	New compounds
SE9901901D0 (sv) *	1999-05-26	1999-05-26	Astra Ab	Compounds
US7384957B2 (en)	2001-12-19	2008-06-10	H. Lundbeck A/S	3,4-dihydro-1H-isoquinolin-2-yl-derivatives
US6608193B2 (en) *	2001-12-21	2003-08-19	The Procter & Gamble Company	Methods for synthesis of amino-tetrahydroisoquinoline ring compounds
ES2295672T3 (es) *	2002-08-07	2008-04-16	Neuraxon Inc.	Compuestos de aminobenzotiazol con actividad inhibitoria de la oxido nitrico sintasa (nos).
US8710045B2 (en)	2004-01-22	2014-04-29	The Trustees Of Columbia University In The City Of New York	Agents for preventing and treating disorders involving modulation of the ryanodine receptors
EP1910321A4 (en) *	2005-07-05	2010-09-01	Astrazeneca Ab	NEW COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF, INTERMEDIATE PRODUCTS, PHARMACEUTICAL COMPOSITIONS AND THEIR USE IN THE TREATMENT OF 5-HT6-MEDIATED ILLNESSES SUCH AS ALZHEIMER'S DISEASE, COGNITIVE ILLUSTRATIONS, SCHOISOPHRENIC ASSOCIATED COGNITIVE DISORDERS, OBESITAS AND PARKINSON DISEASE
US8247403B2 (en)	2007-03-07	2012-08-21	Takeda Pharmaceutical Company Limited	Benzoxazepine derivatives and use thereof
CA3045492C (en)	2016-12-23	2021-10-19	Daiichi Sankyo Company, Limited	Sulfonamide compounds having tnap inhibitory activity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU6286294A (en) *	1993-03-23	1994-10-11	Astra Aktiebolag	Guanidine derivatives useful in therapy
EP0713483B1 (en) *	1993-08-12	2003-01-15	AstraZeneca AB	Amidine derivatives with nitric oxide synthetase activities
EP0723438A1 (en) *	1993-10-04	1996-07-31	The Wellcome Foundation Limited	Substituted urea and isothiourea derivatives as no synthase inhibitors
TW397812B (en) *	1995-02-11	2000-07-11	Astra Ab	Bicyclic isothiourea derivatives useful in therapy

1996
- 1996-10-30 TW TW085113282A patent/TW458978B/zh active
- 1996-11-06 AU AU75927/96A patent/AU701329B2/en not_active Ceased
- 1996-11-06 ES ES96938584T patent/ES2171743T3/es not_active Expired - Lifetime
- 1996-11-06 BR BR9611276A patent/BR9611276A/pt not_active Application Discontinuation
- 1996-11-06 EE EE9800141A patent/EE9800141A/xx unknown
- 1996-11-06 KR KR1019980703356A patent/KR19990067349A/ko not_active Application Discontinuation
- 1996-11-06 IL IL12429696A patent/IL124296A0/xx unknown
- 1996-11-06 WO PCT/SE1996/001425 patent/WO1997017344A1/en not_active Application Discontinuation
- 1996-11-06 HU HU9900142A patent/HUP9900142A3/hu unknown
- 1996-11-06 JP JP9518124A patent/JP2000500132A/ja active Pending
- 1996-11-06 PT PT96938584T patent/PT861250E/pt unknown
- 1996-11-06 AT AT96938584T patent/ATE213241T1/de not_active IP Right Cessation
- 1996-11-06 DE DE69619259T patent/DE69619259T2/de not_active Expired - Fee Related
- 1996-11-06 EP EP96938584A patent/EP0861250B1/en not_active Expired - Lifetime
- 1996-11-06 DK DK96938584T patent/DK0861250T3/da active
- 1996-11-06 SK SK610-98A patent/SK61098A3/sk unknown
- 1996-11-06 SI SI9630451T patent/SI0861250T1/xx unknown
- 1996-11-06 TR TR1998/00813T patent/TR199800813T2/xx unknown
- 1996-11-06 CA CA002235301A patent/CA2235301A1/en not_active Abandoned
- 1996-11-06 CZ CZ981392A patent/CZ139298A3/cs unknown
- 1996-11-06 PL PL96326554A patent/PL326554A1/xx unknown
- 1996-11-06 NZ NZ322227A patent/NZ322227A/xx unknown
1998
- 1998-04-24 IS IS4725A patent/IS4725A/is unknown
- 1998-05-06 NO NO982072A patent/NO982072L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
CZ139298A3 (cs)	1998-09-16
AU7592796A (en)	1997-05-29
WO1997017344A1 (en)	1997-05-15
EP0861250A1 (en)	1998-09-02
SK61098A3 (en)	1999-01-11
HUP9900142A2 (hu)	1999-05-28
KR19990067349A (ko)	1999-08-16
SI0861250T1 (en)	2002-06-30
CA2235301A1 (en)	1997-05-15
NO982072D0 (no)	1998-05-06
PL326554A1 (en)	1998-09-28
JP2000500132A (ja)	2000-01-11
BR9611276A (pt)	1999-01-26
EE9800141A (et)	1998-10-15
IL124296A0 (en)	1998-12-06
ES2171743T3 (es)	2002-09-16
ATE213241T1 (de)	2002-02-15
HUP9900142A3 (en)	2001-08-28
DE69619259T2 (de)	2002-09-19
AU701329B2 (en)	1999-01-28
DE69619259D1 (de)	2002-03-21
TW458978B (en)	2001-10-11
NZ322227A (en)	1999-11-29
TR199800813T2 (xx)	1998-07-21
DK0861250T3 (da)	2002-04-29
MX9803453A (es)	1998-09-30
EP0861250B1 (en)	2002-02-13
IS4725A (is)	1998-04-24
PT861250E (pt)	2002-07-31

Legal Events

Date	Code	Title	Description
2003-04-14	FC2A	Withdrawal, rejection or dismissal of laid open patent application

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SE9803518D0 (sv)	1998-10-15	Novel compounds
NO982072L (no)	1998-07-03	Amidin- og isotioureaderivater som inhibitorer av nitrogenoksydsyntase
NO20004089L (no)	2000-10-16	Nye triazolo(4,5-d)pyrimidinforbindelser
SE9803773D0 (sv)	1998-11-05	Compounds
DK0634396T3 (da)	1999-07-05	Aminosyrederivater og deres anvendelse som enkeltfalinaseinhibitorer
NO20026081L (no)	2003-02-04	Nye forbindelser
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NO995404L (no)	2000-01-05	Forbindelser
SE0202461D0 (sv)	2002-08-14	Novel compounds
SE9904676D0 (sv)	1999-12-20	Novel compounds
SE9901901D0 (sv)	1999-05-26	Compounds
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