SE9701681D0 - New compounds - Google Patents

New compounds

Info

Publication number
SE9701681D0
SE9701681D0 SE9701681A SE9701681A SE9701681D0 SE 9701681 D0 SE9701681 D0 SE 9701681D0 SE 9701681 A SE9701681 A SE 9701681A SE 9701681 A SE9701681 A SE 9701681A SE 9701681 D0 SE9701681 D0 SE 9701681D0
Authority
SE
Sweden
Prior art keywords
new compounds
thienyl
compounds
racemates
therapy
Prior art date
Application number
SE9701681A
Other languages
English (en)
Inventor
James Macdonadld
James Matz
William Shakespeare
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9701681A priority Critical patent/SE9701681D0/sv
Publication of SE9701681D0 publication Critical patent/SE9701681D0/sv
Priority to ARP980101928A priority patent/AR012601A1/es
Priority to US09/068,945 priority patent/US6489322B1/en
Priority to AU74598/98A priority patent/AU734391B2/en
Priority to NZ500675A priority patent/NZ500675A/en
Priority to IL13267898A priority patent/IL132678A0/xx
Priority to HU0001873A priority patent/HUP0001873A3/hu
Priority to MXPA99009882A priority patent/MXPA99009882A/es
Priority to PCT/SE1998/000785 priority patent/WO1998050382A1/en
Priority to CA002288333A priority patent/CA2288333A1/en
Priority to BR9809218-9A priority patent/BR9809218A/pt
Priority to SK1405-99A priority patent/SK140599A3/sk
Priority to EP98921951A priority patent/EP0983268B1/en
Priority to AT98921951T priority patent/ATE221065T1/de
Priority to IDW991284A priority patent/ID22885A/id
Priority to TR1999/02720T priority patent/TR199902720T2/xx
Priority to DE69806750T priority patent/DE69806750T2/de
Priority to JP54796798A priority patent/JP2001523262A/ja
Priority to CN98804840A priority patent/CN1255131A/zh
Priority to PL98336853A priority patent/PL336853A1/xx
Priority to EEP199900474A priority patent/EE9900474A/xx
Priority to KR1019997010177A priority patent/KR20010012228A/ko
Priority to ZA983736A priority patent/ZA983736B/xx
Priority to IS5236A priority patent/IS5236A/is
Priority to NO995403A priority patent/NO995403L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
SE9701681A 1997-05-05 1997-05-05 New compounds SE9701681D0 (sv)

Priority Applications (25)

Application Number Priority Date Filing Date Title
SE9701681A SE9701681D0 (sv) 1997-05-05 1997-05-05 New compounds
ARP980101928A AR012601A1 (es) 1997-05-05 1998-04-24 Derivados de amidina, formulaciones farmaceuticas que los contiene, uso de dichos derivados en la preparacion de medicamentos y proceso para lapreparacion de dichos derivados
KR1019997010177A KR20010012228A (ko) 1997-05-05 1998-04-28 산화질소 신타아제 억제제로서의 아미딘 유도체
BR9809218-9A BR9809218A (pt) 1997-05-05 1998-04-28 Composto, formulação farmacêutica, processos para tratar, ou reduzir o risco de, uma doença ou condição humana, para tratar, ou reduzir o risco de, hipoxia, ou derrame ou isquemia ou condições neurodegenerativas, ou esquizofrenia ou dor ou enxaqueca, ou para a prevenção e reversão da tolerância aos opiatos e diazepinas, ou para o tratamento do vìcio de drogas, para tratar a doença de parkinson, para preparar um composto, e, uso do mesmo.
AT98921951T ATE221065T1 (de) 1997-05-05 1998-04-28 Amidinderivate als inhibitoren von no-synthase
NZ500675A NZ500675A (en) 1997-05-05 1998-04-28 N-(2,3,4,5-tetrahydro-1,4-benzoxazepin-7-yl)-carboximidamide derivatives as inhibitors of nitric oxide synthase
IL13267898A IL132678A0 (en) 1997-05-05 1998-04-28 Amidine derivatives as inhibitors of nitric oxide synthase
HU0001873A HUP0001873A3 (en) 1997-05-05 1998-04-28 Amidino-1,4-benzoxazepine derivatives, process for their preparation, their use and pharmaceutical compositions containing them
MXPA99009882A MXPA99009882A (es) 1997-05-05 1998-04-28 Derivados de amidina como inhibidores de la oxidonitrico sintasa.
PCT/SE1998/000785 WO1998050382A1 (en) 1997-05-05 1998-04-28 Amidine derivatives as inhibitors of nitric oxide synthase
CA002288333A CA2288333A1 (en) 1997-05-05 1998-04-28 Amidine derivatives as inhibitors of nitric oxide synthase
US09/068,945 US6489322B1 (en) 1997-05-05 1998-04-28 Amidine derivatives as inhibitors of nitric oxide synthase
SK1405-99A SK140599A3 (en) 1997-05-05 1998-04-28 Amidine derivatives as inhibitors of nitric oxide synthase
EP98921951A EP0983268B1 (en) 1997-05-05 1998-04-28 Amidine derivatives as inhibitors of nitric oxide synthase
AU74598/98A AU734391B2 (en) 1997-05-05 1998-04-28 Amidine derivatives as inhibitors of nitric oxide synthase
IDW991284A ID22885A (id) 1997-05-05 1998-04-28 Turunan amidina sebagai penghambat nitrik oksida sintase
TR1999/02720T TR199902720T2 (xx) 1997-05-05 1998-04-28 Nitrik oksit sentaz�n�n inhibit�rleri olarak amidin t�revleri.
DE69806750T DE69806750T2 (de) 1997-05-05 1998-04-28 Amidinderivate als inhibitoren von no-synthase
JP54796798A JP2001523262A (ja) 1997-05-05 1998-04-28 一酸化窒素シンターゼの阻害剤としてのアミジン誘導体
CN98804840A CN1255131A (zh) 1997-05-05 1998-04-28 作为氧化氮合酶抑制剂的脒衍生物
PL98336853A PL336853A1 (en) 1997-05-05 1998-04-28 Derivatives of amidine as inhibitors of nitrogen oxide synthase
EEP199900474A EE9900474A (et) 1997-05-05 1998-04-28 Amidiini derivaadid lämmastikoksiidi süntaasi inhibiitoritena
ZA983736A ZA983736B (en) 1997-05-05 1998-05-04 New compounds
IS5236A IS5236A (is) 1997-05-05 1999-11-01 Amidínafleiður sem hemlar gegn nituroxíðsyntasa
NO995403A NO995403L (no) 1997-05-05 1999-11-04 Amidinderivater som inhibitorer av nitrogenoksydsyntase

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9701681A SE9701681D0 (sv) 1997-05-05 1997-05-05 New compounds

Publications (1)

Publication Number Publication Date
SE9701681D0 true SE9701681D0 (sv) 1997-05-05

Family

ID=20406835

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9701681A SE9701681D0 (sv) 1997-05-05 1997-05-05 New compounds

Country Status (25)

Country Link
US (1) US6489322B1 (sv)
EP (1) EP0983268B1 (sv)
JP (1) JP2001523262A (sv)
KR (1) KR20010012228A (sv)
CN (1) CN1255131A (sv)
AR (1) AR012601A1 (sv)
AT (1) ATE221065T1 (sv)
AU (1) AU734391B2 (sv)
BR (1) BR9809218A (sv)
CA (1) CA2288333A1 (sv)
DE (1) DE69806750T2 (sv)
EE (1) EE9900474A (sv)
HU (1) HUP0001873A3 (sv)
ID (1) ID22885A (sv)
IL (1) IL132678A0 (sv)
IS (1) IS5236A (sv)
MX (1) MXPA99009882A (sv)
NO (1) NO995403L (sv)
NZ (1) NZ500675A (sv)
PL (1) PL336853A1 (sv)
SE (1) SE9701681D0 (sv)
SK (1) SK140599A3 (sv)
TR (1) TR199902720T2 (sv)
WO (1) WO1998050382A1 (sv)
ZA (1) ZA983736B (sv)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI243164B (en) * 2001-02-13 2005-11-11 Aventis Pharma Gmbh Acylated indanyl amines and their use as pharmaceuticals
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
EP1876654B1 (en) * 2005-04-26 2018-03-21 Kabushiki Kaisha Toshiba White led, and backlight and liquid crystal display device using the same
WO2007004959A1 (en) * 2005-07-05 2007-01-11 Astrazeneca Ab New compounds, process for their preparation, intermediates, pharmaceutical compositions and their use in the treatment of 5-ht6 mediated disorders such as alzheimer's disease, cognitive disorders, cognitive impairment associated with schizophrenia, obesity and parkinson's disease
MY148644A (en) 2005-07-18 2013-05-15 Orion Corp New pharmaceutical compounds
US8263587B2 (en) * 2006-11-02 2012-09-11 Piramal Healthcare Limited Benzoxazepine compounds, their preparation and use
JP5497429B2 (ja) 2007-03-07 2014-05-21 武田薬品工業株式会社 ベンゾオキサゼピン誘導体およびその用途
WO2008144483A2 (en) * 2007-05-18 2008-11-27 Armgo Pharma, Inc. Agents for treating disorders involving modulation of ryanodine receptors
CA2763099A1 (en) * 2009-05-22 2010-11-25 Exelixis, Inc. Benzoxazepines based p13k/mt0r inhibitors against proliferative diseases

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09501918A (ja) 1993-08-12 1997-02-25 アストラ・アクチエボラーグ 酸化窒素合成酵素活性を有するアミジン誘導体
AU7705694A (en) 1993-10-04 1995-05-01 Glaxo Wellcome House Substituted urea and isothiourea derivatives as no synthase inhibitors
RU2136661C1 (ru) 1993-10-21 1999-09-10 Джи Ди Сирл энд Ко. Амидинопроизводные, их применение и фармацевтическая композиция
WO1997006158A1 (en) 1995-08-10 1997-02-20 Astra Aktiebolag Bicyclic amidine derivatives useful in therapy
AU682768B2 (en) * 1994-05-07 1997-10-16 Astra Aktiebolag Bicyclic amidine derivatives as inhibitors of nitric oxide synthetase
TW397812B (en) 1995-02-11 2000-07-11 Astra Ab Bicyclic isothiourea derivatives useful in therapy
TW458978B (en) 1995-11-07 2001-10-11 Astra Ab Amidine and isothiourea derivatives as inhibitors of nitric oxide synthase

Also Published As

Publication number Publication date
NO995403D0 (no) 1999-11-04
DE69806750T2 (de) 2003-03-06
ID22885A (id) 1999-12-16
NZ500675A (en) 2001-05-25
CA2288333A1 (en) 1998-11-12
BR9809218A (pt) 2000-06-27
US6489322B1 (en) 2002-12-03
DE69806750D1 (de) 2002-08-29
IL132678A0 (en) 2001-03-19
EE9900474A (et) 2000-06-15
CN1255131A (zh) 2000-05-31
AU734391B2 (en) 2001-06-14
AU7459898A (en) 1998-11-27
TR199902720T2 (xx) 2000-02-21
PL336853A1 (en) 2000-07-17
SK140599A3 (en) 2000-06-12
IS5236A (is) 1999-11-01
KR20010012228A (ko) 2001-02-15
ZA983736B (en) 1998-11-05
ATE221065T1 (de) 2002-08-15
WO1998050382A1 (en) 1998-11-12
JP2001523262A (ja) 2001-11-20
HUP0001873A2 (hu) 2001-01-29
AR012601A1 (es) 2000-11-08
HUP0001873A3 (en) 2001-12-28
NO995403L (no) 2000-01-05
EP0983268B1 (en) 2002-07-24
MXPA99009882A (es) 2005-11-22
EP0983268A1 (en) 2000-03-08

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