NO940600L - Substituerte benzensulfonylurinstoffer og -tiourinstoffer, fremgangsmåter for fremstilling av dem og deres anvendelse som farmasöytika - Google Patents
Substituerte benzensulfonylurinstoffer og -tiourinstoffer, fremgangsmåter for fremstilling av dem og deres anvendelse som farmasöytikaInfo
- Publication number
- NO940600L NO940600L NO940600A NO940600A NO940600L NO 940600 L NO940600 L NO 940600L NO 940600 A NO940600 A NO 940600A NO 940600 A NO940600 A NO 940600A NO 940600 L NO940600 L NO 940600L
- Authority
- NO
- Norway
- Prior art keywords
- alkyl
- thioureas
- hal
- arrhythmias
- pharmaceuticals
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/45—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups at least one of the singly-bound nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom, e.g. N-acylaminosulfonamides
- C07C311/46—Y being a hydrogen or a carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C311/52—Y being a hetero atom
- C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
- C07C311/57—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
- C07C311/58—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/40—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of thiourea or isothiourea groups further bound to other hetero atoms
- C07C335/42—Sulfonylthioureas; Sulfonylisothioureas
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4305450 | 1993-02-23 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO940600D0 NO940600D0 (no) | 1994-02-22 |
| NO940600L true NO940600L (no) | 1994-08-24 |
| NO300173B1 NO300173B1 (no) | 1997-04-21 |
Family
ID=6481073
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO940600A NO300173B1 (no) | 1993-02-23 | 1994-02-22 | Substituerte benzensulfonylurinstoffer og -tiourinstoffer og deres anvendelse til fremstilling av farmasöytika, samt legemidler inneholdende disse |
Country Status (18)
| Country | Link |
|---|---|
| US (6) | US5574069A (no) |
| EP (1) | EP0612724B1 (no) |
| JP (1) | JP2778450B2 (no) |
| AT (1) | ATE146775T1 (no) |
| AU (1) | AU664940B2 (no) |
| CA (1) | CA2116165C (no) |
| CY (1) | CY2034A (no) |
| DE (1) | DE59401361D1 (no) |
| DK (1) | DK0612724T3 (no) |
| ES (1) | ES2098069T3 (no) |
| FI (1) | FI114152B (no) |
| GR (1) | GR3022550T3 (no) |
| HK (1) | HK1006166A1 (no) |
| HU (1) | HU219639B (no) |
| NO (1) | NO300173B1 (no) |
| NZ (1) | NZ250925A (no) |
| PL (2) | PL175795B1 (no) |
| TW (1) | TW429245B (no) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2098069T3 (es) | 1993-02-23 | 1997-04-16 | Hoechst Ag | Bencenosulfonil-ureas y -tioureas sustituidas, procedimiento para su preparacion y su utilizacion como agentes farmaceuticos. |
| DE19503136A1 (de) * | 1995-02-01 | 1996-08-08 | Hoechst Ag | Substituierte Thiophenylsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE19504379A1 (de) * | 1995-02-10 | 1996-08-14 | Hoechst Ag | Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung pharmazeutischer Präparate sowie sie enthaltende pharmazeutische Präparate |
| DE19505397A1 (de) * | 1995-02-17 | 1996-08-22 | Hoechst Ag | Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| HU226462B1 (en) * | 1995-02-17 | 2008-12-29 | Hoechst Ag | Substituted benzol-sulfonyl-ureas and -thioureas, process for producing them, pharmaceutical compositions containing them, and their use |
| ZA961314B (en) * | 1995-02-21 | 1996-08-27 | Hoechst Ag | Substituted benzenesulfonylureas and -thioreas processes for their preparation their use for the production of pharmaceutical preparations and medicaments containing them |
| DE19540995A1 (de) * | 1995-11-03 | 1997-05-07 | Hoechst Ag | Substituierte Sulfonimidamide, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| DE19542306A1 (de) * | 1995-11-14 | 1997-05-15 | Hoechst Ag | Sulfonylamino-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
| PL316439A1 (en) * | 1995-11-20 | 1997-05-26 | Hoechst Ag | Novel substituted derivatives of benzoyloguanidine, method of obtaining them, their application in production of pharmaceutic and diagnostic agents and pharmaceutic agent as such |
| DE19546736A1 (de) * | 1995-12-14 | 1997-06-19 | Hoechst Ag | Substituierte Chromanylsulfonyl(thio)harnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung pharmazeutischer Präparate |
| DE19647000A1 (de) * | 1996-11-14 | 1998-05-20 | Hoechst Ag | 3-Amido-chromanylsulfonyl(thio)harnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
| DE19832009A1 (de) * | 1998-07-16 | 2000-01-20 | Hoechst Marion Roussel De Gmbh | 2,5-Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharamazeutische Präparate |
| PL194986B1 (pl) * | 1998-09-10 | 2007-07-31 | Sanofi Aventis Deutschland | Środek farmaceutyczny i zastosowanie benzenosulfonylo(tio)moczników |
| DE19917233A1 (de) * | 1999-04-16 | 2000-10-19 | Aventis Pharma Gmbh | Kristalline Formen des Natriumsalzes des 5-Chlor-2-methoxy-N-(2-(4-methoxy-3-methylaminothiocarbonylaminosulfonyl-phenyl)-ethyl)- benzamids |
| DE19923086A1 (de) | 1999-05-20 | 2000-11-23 | Aventis Pharma Gmbh | Cinnamoylaminoalkyl-substituierte Benzolsulfonamidderivate, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
| JP3891934B2 (ja) | 2000-10-17 | 2007-03-14 | 旭化成ケミカルズ株式会社 | ポリイソシアネート組成物の製造方法 |
| DE10054482A1 (de) | 2000-11-03 | 2002-05-08 | Aventis Pharma Gmbh | Heteroarylacryloylaminoalkyl-substituierte Benzolsulfonamidderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
| DE10054481A1 (de) | 2000-11-03 | 2002-05-08 | Aventis Pharma Gmbh | Acylaminoalkyl-substituierte Benzolsulfonamidderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
| US8472428B2 (en) | 2001-02-27 | 2013-06-25 | Verizon Data Services Llc | Methods and systems for line management |
| DE10129704A1 (de) * | 2001-06-22 | 2003-01-02 | Aventis Pharma Gmbh | Verwendung von Benzolsulfonyl(thio)harnstoffen in der Behandlung des septischen Schocks |
| US6835853B2 (en) * | 2001-10-31 | 2004-12-28 | Synthon Bv | Process for resolution of tamsulosin and compounds, compositions, and processes associated therewith |
| DE102004061017A1 (de) * | 2004-12-18 | 2006-06-22 | Sanofi-Aventis Deutschland Gmbh | Piperidinsulfonylharnstoffe und -thioharnstoffe, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
| EP2026766A1 (en) | 2006-05-17 | 2009-02-25 | Synthon B.V. | Tablet composition with a prolonged release of tamsulosin |
| CA2651732C (en) | 2006-05-18 | 2014-10-14 | Mannkind Corporation | Intracellular kinase inhibitors |
| KR101608702B1 (ko) * | 2007-06-05 | 2016-04-04 | 사노피 | 디(헤테로)아릴사이클로헥산 유도체, 이들의 제조방법, 이들의 용도 및 이들을 포함하는 약제학적 조성물 |
| US8465770B2 (en) * | 2008-12-24 | 2013-06-18 | Synthon Bv | Low dose controlled release tablet |
| WO2010148177A2 (en) * | 2009-06-17 | 2010-12-23 | The Board Of Trustees Of The Leland Stanford Junior University | Compounds, compositions, methods of synthesis, and methods of treatment |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE243821C (no) * | ||||
| DE1185180B (de) * | 1963-10-19 | 1965-01-14 | Hoechst Ag | Verfahren zur Herstellung von Benzolsulfonylharnstoffen |
| DE1518874C3 (de) * | 1964-10-07 | 1975-03-13 | Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt | Benzolsulfonylharnstoffe und Verfahren zu ihrer Herstellung |
| DE1443919C3 (de) * | 1964-12-28 | 1973-11-29 | Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt | Benzolsulfonylharnstoffe, Ver fahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitun gen |
| NL128362C (no) * | 1965-03-16 | |||
| US3297696A (en) * | 1965-05-28 | 1967-01-10 | Sandoz Ag | 6-amino-8, 9-dihydro-13bh-isoquinolo-[2, 1-c] quinazolines and intermediates therefor |
| GB1122830A (en) * | 1965-10-09 | 1968-08-07 | Ferranti Ltd | Improvements relating to character transmission and reproduction systems |
| US3917690A (en) * | 1966-11-29 | 1975-11-04 | Hoechst Ag | Benzenesulfonyl ureas and process for their manufacture |
| DE1568648C3 (de) * | 1966-12-19 | 1975-03-27 | Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt | Benzolsulfonylharnstoffe, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate |
| US3517015A (en) * | 1969-03-10 | 1970-06-23 | Sandoz Ag | Tetrahydro-isoquino(2,1-d)(1,4)benzodiazepines |
| US3965173A (en) * | 1971-05-21 | 1976-06-22 | Chubb Francis L | Process for preparing p-(5-chloro-2-methoxy-benzamidoethyl)-benzene sulfonamide |
| DE2413514C3 (de) * | 1974-03-21 | 1982-03-04 | Hoechst Ag, 6000 Frankfurt | N-Acylaminoathylbenzolsulfonyl-N'-methylharnstoffe, Verfahren zu ihrer Herstellung und deren Verwendung |
| US3988968A (en) * | 1974-12-23 | 1976-11-02 | Miller Fluid Power Corporation | Stop tube for cylinder assemblies |
| DE2600513A1 (de) * | 1976-01-08 | 1977-07-28 | Hoechst Ag | Acylamino(alkyl)benzolderivate und verfahren zu ihrer herstellung |
| DE3011153A1 (de) * | 1980-03-22 | 1981-10-15 | Hoechst Ag, 6000 Frankfurt | Verwendung von n-(4- spitze klammer auf 2-(5-chlor-2-methoxy-benzamido)-aethylspitze klammer zu -benzolsulfonyl)-n'-methyl-harnstoff |
| US5215985A (en) * | 1990-07-20 | 1993-06-01 | E. R. Squibb & Sons, Inc. | Method for treating ischemic insult to neurons employing an ATP-sensitive potassium channel blocker |
| ES2098069T3 (es) * | 1993-02-23 | 1997-04-16 | Hoechst Ag | Bencenosulfonil-ureas y -tioureas sustituidas, procedimiento para su preparacion y su utilizacion como agentes farmaceuticos. |
-
1994
- 1994-02-16 ES ES94102321T patent/ES2098069T3/es not_active Expired - Lifetime
- 1994-02-16 DE DE59401361T patent/DE59401361D1/de not_active Expired - Lifetime
- 1994-02-16 DK DK94102321.0T patent/DK0612724T3/da active
- 1994-02-16 AT AT94102321T patent/ATE146775T1/de active
- 1994-02-16 EP EP94102321A patent/EP0612724B1/de not_active Expired - Lifetime
- 1994-02-21 AU AU55279/94A patent/AU664940B2/en not_active Expired
- 1994-02-21 NZ NZ250925A patent/NZ250925A/en not_active IP Right Cessation
- 1994-02-21 FI FI940810A patent/FI114152B/fi not_active IP Right Cessation
- 1994-02-22 NO NO940600A patent/NO300173B1/no not_active IP Right Cessation
- 1994-02-22 PL PL94302325A patent/PL175795B1/pl unknown
- 1994-02-22 JP JP6024119A patent/JP2778450B2/ja not_active Expired - Lifetime
- 1994-02-22 PL PL94326170A patent/PL179268B1/pl unknown
- 1994-02-22 CA CA002116165A patent/CA2116165C/en not_active Expired - Lifetime
- 1994-02-23 HU HU9400525A patent/HU219639B/hu unknown
- 1994-03-25 TW TW083102607A patent/TW429245B/zh not_active IP Right Cessation
-
1995
- 1995-02-23 US US08/393,027 patent/US5574069A/en not_active Expired - Lifetime
-
1996
- 1996-09-03 US US08/707,103 patent/US5698596A/en not_active Expired - Lifetime
- 1996-11-07 US US08/744,314 patent/US5776980A/en not_active Expired - Lifetime
-
1997
- 1997-02-12 GR GR970400240T patent/GR3022550T3/el unknown
-
1998
- 1998-02-20 CY CY203498A patent/CY2034A/xx unknown
- 1998-05-19 US US09/081,143 patent/US6090981A/en not_active Expired - Lifetime
- 1998-06-12 HK HK98105247A patent/HK1006166A1/xx not_active IP Right Cessation
-
2000
- 2000-01-24 US US09/490,078 patent/US6335467B1/en not_active Expired - Lifetime
-
2001
- 2001-11-29 US US09/995,782 patent/US6506937B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2778450B2 (ja) | 1998-07-23 |
| PL179268B1 (pl) | 2000-08-31 |
| US6090981A (en) | 2000-07-18 |
| EP0612724A1 (de) | 1994-08-31 |
| FI114152B (fi) | 2004-08-31 |
| PL175795B1 (pl) | 1999-02-26 |
| NO300173B1 (no) | 1997-04-21 |
| FI940810A0 (fi) | 1994-02-21 |
| CA2116165C (en) | 2006-02-21 |
| AU664940B2 (en) | 1995-12-07 |
| CA2116165A1 (en) | 1994-08-24 |
| ES2098069T3 (es) | 1997-04-16 |
| DE59401361D1 (de) | 1997-02-06 |
| NO940600D0 (no) | 1994-02-22 |
| NZ250925A (en) | 1995-09-26 |
| HK1006166A1 (en) | 1999-02-12 |
| ATE146775T1 (de) | 1997-01-15 |
| FI940810A (fi) | 1994-08-24 |
| DK0612724T3 (da) | 1997-06-16 |
| US5776980A (en) | 1998-07-07 |
| US5574069A (en) | 1996-11-12 |
| HU9400525D0 (en) | 1994-05-30 |
| AU5527994A (en) | 1994-09-01 |
| US6506937B2 (en) | 2003-01-14 |
| US5698596A (en) | 1997-12-16 |
| PL302325A1 (en) | 1994-09-05 |
| HUT71104A (en) | 1995-11-28 |
| HU219639B (hu) | 2001-06-28 |
| GR3022550T3 (en) | 1997-05-31 |
| US6335467B1 (en) | 2002-01-01 |
| EP0612724B1 (de) | 1996-12-27 |
| JPH07304728A (ja) | 1995-11-21 |
| CY2034A (en) | 1998-02-20 |
| US20020058838A1 (en) | 2002-05-16 |
| TW429245B (en) | 2001-04-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK1K | Patent expired |