NO970964L - Ortosubstituerte benzoylguanidiner, fremgangsmåter for deres fremstilling, deres anvendelse som medikament eller diagnostikum samt medikamenter inneholdende forbindelsene - Google Patents
Ortosubstituerte benzoylguanidiner, fremgangsmåter for deres fremstilling, deres anvendelse som medikament eller diagnostikum samt medikamenter inneholdende forbindelseneInfo
- Publication number
- NO970964L NO970964L NO970964A NO970964A NO970964L NO 970964 L NO970964 L NO 970964L NO 970964 A NO970964 A NO 970964A NO 970964 A NO970964 A NO 970964A NO 970964 L NO970964 L NO 970964L
- Authority
- NO
- Norway
- Prior art keywords
- atoms
- processes
- ortho
- diagnostic
- drug
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Det er beskrevet ortosubstituerte benzoylgumidiner med formel (I): hvta- Sl(l) til R(4) kan ha mange betydninger, og blant annet ha følgende betydning: R(l) betyr H, F, Cl, alkyl med 1, 2, 3 eller 4 C-atomer, alkoksy med 1, 2, 3 eller 4 C-atomer, cykloalkyl med 5 eller 6 C-atomer, cykloalkoksy med^ 5 eller 6 C-atomer eller Xa-CF3; hvor X betyr oksygen og a er 0 eller 1; R(Z) og R(3) kan være definert som R(l) og R(<) kan f.eks. bety iretyl. Blsse forljlndelsene er egnede sora antlaiTtmiske legemidler med kardlobeskyttende komponenter for Infarkt- jrofyloksc og Infarktbehandl Infi samt for behandling av nnglna pectoris. De Inhiberer også preventivt de paLofyslologlske prosessene ved opptreden av Ischemlsk Induserte skader, spesielt ved utløsningen av Ischemlsk induserte hjertearytmier.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19608162A DE19608162A1 (de) | 1996-03-04 | 1996-03-04 | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
Publications (2)
Publication Number | Publication Date |
---|---|
NO970964D0 NO970964D0 (no) | 1997-03-03 |
NO970964L true NO970964L (no) | 1997-09-05 |
Family
ID=7787088
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO970964A NO970964L (no) | 1996-03-04 | 1997-03-03 | Ortosubstituerte benzoylguanidiner, fremgangsmåter for deres fremstilling, deres anvendelse som medikament eller diagnostikum samt medikamenter inneholdende forbindelsene |
Country Status (22)
Country | Link |
---|---|
US (1) | US6153651A (no) |
EP (1) | EP0794171A3 (no) |
JP (1) | JPH09328462A (no) |
KR (1) | KR970065512A (no) |
CN (1) | CN1160041A (no) |
AR (1) | AR006052A1 (no) |
AU (1) | AU707403B2 (no) |
BR (1) | BR9701160A (no) |
CA (1) | CA2198979A1 (no) |
CZ (1) | CZ65397A3 (no) |
DE (1) | DE19608162A1 (no) |
HR (1) | HRP970126A2 (no) |
HU (1) | HUP9700543A3 (no) |
IL (1) | IL120359A0 (no) |
MY (1) | MY129959A (no) |
NO (1) | NO970964L (no) |
NZ (1) | NZ314326A (no) |
PL (1) | PL318416A1 (no) |
SK (1) | SK27597A3 (no) |
TR (1) | TR199700128A2 (no) |
TW (1) | TW386989B (no) |
ZA (1) | ZA971814B (no) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19624178A1 (de) * | 1996-06-18 | 1998-01-08 | Hoechst Ag | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL34667C (no) * | 1931-09-01 | |||
DE3929582A1 (de) * | 1989-09-06 | 1991-03-07 | Hoechst Ag | Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament |
TW250477B (no) * | 1992-12-15 | 1995-07-01 | Hoechst Ag | |
IL109570A0 (en) * | 1993-05-17 | 1994-08-26 | Fujisawa Pharmaceutical Co | Guanidine derivatives, pharmaceutical compositions containing the same and processes for the preparation thereof |
DE4318658A1 (de) * | 1993-06-04 | 1994-12-08 | Hoechst Ag | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
DE4318756A1 (de) * | 1993-06-05 | 1994-12-08 | Hoechst Ag | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
DE4325822A1 (de) * | 1993-07-31 | 1995-02-02 | Hoechst Ag | Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
DE4328869A1 (de) * | 1993-08-27 | 1995-03-02 | Hoechst Ag | Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
DE4404183A1 (de) * | 1994-02-10 | 1995-08-17 | Merck Patent Gmbh | 4-Amino-1-piperidylbenzoylguanidine |
DE4421495A1 (de) * | 1994-06-20 | 1995-12-21 | Merck Patent Gmbh | Heterocyclyloxy-benzoylguanidine |
DE4430861A1 (de) * | 1994-08-31 | 1996-03-07 | Merck Patent Gmbh | Heterocyclyl-benzoylguanidine |
-
1996
- 1996-03-04 DE DE19608162A patent/DE19608162A1/de not_active Withdrawn
-
1997
- 1997-02-11 PL PL97318416A patent/PL318416A1/xx unknown
- 1997-02-19 EP EP97102606A patent/EP0794171A3/de not_active Withdrawn
- 1997-02-27 TW TW086102368A patent/TW386989B/zh not_active IP Right Cessation
- 1997-02-28 AU AU14998/97A patent/AU707403B2/en not_active Ceased
- 1997-02-28 AR ARP970100821A patent/AR006052A1/es unknown
- 1997-02-28 SK SK275-97A patent/SK27597A3/sk unknown
- 1997-02-28 US US08/808,295 patent/US6153651A/en not_active Expired - Fee Related
- 1997-02-28 NZ NZ314326A patent/NZ314326A/en unknown
- 1997-02-28 CN CN97102832A patent/CN1160041A/zh active Pending
- 1997-03-03 BR BR9701160A patent/BR9701160A/pt active Search and Examination
- 1997-03-03 TR TR97/00128A patent/TR199700128A2/xx unknown
- 1997-03-03 ZA ZA9701814A patent/ZA971814B/xx unknown
- 1997-03-03 CA CA002198979A patent/CA2198979A1/en not_active Abandoned
- 1997-03-03 IL IL12035997A patent/IL120359A0/xx unknown
- 1997-03-03 CZ CZ97653A patent/CZ65397A3/cs unknown
- 1997-03-03 HR HR19608162.9A patent/HRP970126A2/xx not_active Application Discontinuation
- 1997-03-03 NO NO970964A patent/NO970964L/no not_active Application Discontinuation
- 1997-03-03 MY MYPI97000836A patent/MY129959A/en unknown
- 1997-03-03 JP JP9047478A patent/JPH09328462A/ja active Pending
- 1997-03-04 KR KR1019970006965A patent/KR970065512A/ko not_active Application Discontinuation
- 1997-03-04 HU HU9700543A patent/HUP9700543A3/hu unknown
Also Published As
Publication number | Publication date |
---|---|
AU707403B2 (en) | 1999-07-08 |
HRP970126A2 (en) | 1998-04-30 |
CZ65397A3 (cs) | 1998-05-13 |
US6153651A (en) | 2000-11-28 |
ZA971814B (en) | 1997-09-04 |
BR9701160A (pt) | 1998-12-15 |
SK27597A3 (en) | 1997-11-05 |
HUP9700543A2 (en) | 1997-12-29 |
TR199700128A2 (tr) | 1997-09-21 |
CA2198979A1 (en) | 1997-09-04 |
MY129959A (en) | 2007-05-31 |
IL120359A0 (en) | 1997-07-13 |
EP0794171A3 (de) | 1998-08-19 |
MX9701618A (es) | 1997-09-30 |
DE19608162A1 (de) | 1997-09-11 |
AR006052A1 (es) | 1999-07-21 |
TW386989B (en) | 2000-04-11 |
HUP9700543A3 (en) | 2000-03-28 |
PL318416A1 (en) | 1997-09-15 |
HU9700543D0 (en) | 1997-04-28 |
JPH09328462A (ja) | 1997-12-22 |
AU1499897A (en) | 1997-09-11 |
KR970065512A (ko) | 1997-10-13 |
NO970964D0 (no) | 1997-03-03 |
CN1160041A (zh) | 1997-09-24 |
EP0794171A2 (de) | 1997-09-10 |
NZ314326A (en) | 1997-11-24 |
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Legal Events
Date | Code | Title | Description |
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |