NO320952B1 - Fremgangsmate for virusfiltrering av en losning inneholdende minst ett makromolekyl - Google Patents
Fremgangsmate for virusfiltrering av en losning inneholdende minst ett makromolekyl Download PDFInfo
- Publication number
- NO320952B1 NO320952B1 NO19965523A NO965523A NO320952B1 NO 320952 B1 NO320952 B1 NO 320952B1 NO 19965523 A NO19965523 A NO 19965523A NO 965523 A NO965523 A NO 965523A NO 320952 B1 NO320952 B1 NO 320952B1
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- Norway
- Prior art keywords
- virus
- solution
- macromolecule
- protein
- filtration
- Prior art date
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/644—Coagulation factor IXa (3.4.21.22)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/36—Blood coagulation or fibrinolysis factors
- A61K38/37—Factors VIII
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/38—Albumins
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- A—HUMAN NECESSITIES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4717—Plasma globulins, lactoglobulin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/76—Albumins
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
- C07K14/8121—Serpins
- C07K14/8128—Antithrombin III
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/02—Recovery or purification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21022—Coagulation factor IXa (3.4.21.22)
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Toxicology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Water Supply & Treatment (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Glass Compositions (AREA)
- Devices For Conveying Motion By Means Of Endless Flexible Members (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9402254A SE502820C2 (sv) | 1994-06-23 | 1994-06-23 | Filtrering |
SE9500724A SE9500724D0 (sv) | 1994-06-23 | 1995-02-24 | Filtrering |
PCT/SE1995/000777 WO1996000237A1 (en) | 1994-06-23 | 1995-06-22 | Filtration |
Publications (3)
Publication Number | Publication Date |
---|---|
NO965523L NO965523L (no) | 1996-12-20 |
NO965523D0 NO965523D0 (no) | 1996-12-20 |
NO320952B1 true NO320952B1 (no) | 2006-02-20 |
Family
ID=26662085
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19965523A NO320952B1 (no) | 1994-06-23 | 1996-12-20 | Fremgangsmate for virusfiltrering av en losning inneholdende minst ett makromolekyl |
Country Status (16)
Country | Link |
---|---|
US (4) | US6486306B1 (ja) |
EP (1) | EP0796269B1 (ja) |
JP (1) | JP3676370B2 (ja) |
AT (1) | ATE212354T1 (ja) |
CA (1) | CA2192683C (ja) |
DE (2) | DE69525176T2 (ja) |
DK (1) | DK0796269T3 (ja) |
ES (1) | ES2105992T3 (ja) |
FI (1) | FI965145A0 (ja) |
GR (1) | GR970300038T1 (ja) |
MX (1) | MX9606639A (ja) |
NO (1) | NO320952B1 (ja) |
NZ (1) | NZ288789A (ja) |
PT (1) | PT796269E (ja) |
SE (1) | SE9500724D0 (ja) |
WO (1) | WO1996000237A1 (ja) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
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SE9500724D0 (sv) * | 1994-06-23 | 1995-02-24 | Pharmacia Ab | Filtrering |
SE9500778D0 (sv) * | 1995-03-03 | 1995-03-03 | Pharmacia Ab | Process for producing a protein |
SE9603068D0 (sv) * | 1996-08-23 | 1996-08-23 | Pharmacia & Upjohn Ab | Process for purifying a protein |
SE9603303D0 (sv) | 1996-09-11 | 1996-09-11 | Pharmacia & Upjohn Ab | Process for purifying a protein |
EP0860444A1 (en) * | 1997-02-24 | 1998-08-26 | Stichting Centraal Laboratorium van de Bloedtransfusiedienst van het Nederlandse Rode Kruis (CLB) | Method for removing viruses from a protein solution |
US6045588A (en) | 1997-04-29 | 2000-04-04 | Whirlpool Corporation | Non-aqueous washing apparatus and method |
US6096872A (en) * | 1997-10-14 | 2000-08-01 | Ortho Diagnostic Systems, Inc. | Viral clearance process |
FR2772381B1 (fr) * | 1997-12-15 | 2001-06-08 | Lab Francais Du Fractionnement | Procede de preparation par filtration d'une solution de facteur viii securisee viralement |
US6861001B2 (en) * | 1999-12-02 | 2005-03-01 | The General Hospital Corporation | Methods for removal, purification, and concentration of viruses, and methods of therapy based thereupon |
ATE555666T1 (de) | 2002-05-23 | 2012-05-15 | Ortho Clinical Diagnostics Inc | Einfang, konzentration und quantifizierung eines abnormalen prionproteins aus biologischen flüssigkeiten mittels tiefenfiltration |
PT1534404E (pt) | 2002-06-14 | 2007-03-30 | Centocor Inc | Utilização de um modificador de clatratos para promover a passagem de proteínas durante a nanofiltração |
JP2004099506A (ja) * | 2002-09-09 | 2004-04-02 | Mitsubishi Rayon Co Ltd | アミノ酸アミドの製造方法 |
ES2543978T3 (es) * | 2003-04-09 | 2015-08-26 | The Chemo-Sero-Therapeutic Research Institute | Proceso para la producción de una preparación de albúmina |
CN100398642C (zh) * | 2003-06-20 | 2008-07-02 | 迈克必斯生物***公司 | 病毒生产的改进 |
JP4558652B2 (ja) * | 2003-06-20 | 2010-10-06 | マイクロビクス・バイオシステムズ・インコーポレイテツド | ウイルス生産の改善 |
FR2861395B1 (fr) | 2003-10-23 | 2006-02-17 | Lab Francais Du Fractionnement | Facteur viii viralement securise a faible teneur en multimeres superieurs |
US7739891B2 (en) | 2003-10-31 | 2010-06-22 | Whirlpool Corporation | Fabric laundering apparatus adapted for using a select rinse fluid |
US7695524B2 (en) | 2003-10-31 | 2010-04-13 | Whirlpool Corporation | Non-aqueous washing machine and methods |
ES2926359T3 (es) | 2003-12-01 | 2022-10-25 | Novo Nordisk Healthcare Ag | Filtración de virus de composiciones líquidas del Factor VII |
CA2555412C (en) | 2004-02-23 | 2013-06-25 | Crucell Holland B.V. | Virus purification methods |
FR2866890B1 (fr) * | 2004-02-27 | 2008-04-04 | Lab Francais Du Fractionnement | Procede de purification d'albumine comprenant une etape de nanofiltration, solution et composition a usage therapeutique la contenant |
US7837741B2 (en) | 2004-04-29 | 2010-11-23 | Whirlpool Corporation | Dry cleaning method |
US7141171B2 (en) * | 2004-05-21 | 2006-11-28 | Wisconsin Alumni Research Foundation | Membrane cascade-based separation |
AU2005229674B2 (en) | 2004-11-18 | 2010-11-04 | Kedrion Melville Inc. | Low concentration solvent/detergent process of immuneglobulin with pre-treatment |
CA2602944C (en) | 2005-04-11 | 2015-08-11 | Crucell Holland B.V. | Virus purification using ultrafiltration |
US7966684B2 (en) | 2005-05-23 | 2011-06-28 | Whirlpool Corporation | Methods and apparatus to accelerate the drying of aqueous working fluids |
RU2468032C2 (ru) * | 2006-06-26 | 2012-11-27 | Омрикс Биофармасьютикалс Инк. | Способ очистки раствора тромбина от инфекционных частиц |
JP5579599B2 (ja) * | 2007-06-15 | 2014-08-27 | アムジエン・インコーポレーテツド | バイオリアクターにおいて使用する細胞培養培地の処理方法 |
KR100870423B1 (ko) * | 2007-06-27 | 2008-11-26 | 주식회사 하이닉스반도체 | 반도체메모리소자 |
US7989593B1 (en) | 2010-05-27 | 2011-08-02 | Bing Lou Wong | Method for the preparation of a high-temperature stable oxygen-carrier-containing pharmaceutical composition and the use thereof |
US7932356B1 (en) | 2010-06-23 | 2011-04-26 | Bing Lou Wong | Method for the preparation of a heat stable oxygen carrier-containing pharmaceutical composition |
US8048856B1 (en) | 2010-06-23 | 2011-11-01 | Billion King, Ltd. | Treatment methods using a heat stable oxygen carrier-containing pharmaceutical composition |
US8084581B1 (en) | 2011-04-29 | 2011-12-27 | Bing Lou Wong | Method for removing unmodified hemoglobin from cross-linked hemoglobin solutions including polymeric hemoglobin with a high temperature short time heat treatment apparatus |
US9359397B2 (en) | 2011-06-24 | 2016-06-07 | Asahi Kasei Medical Co., Ltd. | Method for manufacturing protein drug |
US20130052232A1 (en) | 2011-08-31 | 2013-02-28 | Bing Lou Wong | Method for the preparation of a heat stable oxygen carrier-containing composition facilating beta-beta cross-linking |
US9294158B2 (en) | 2012-08-07 | 2016-03-22 | Broadcom Corporation | Broadcast audio service |
NZ631126A (en) * | 2013-08-08 | 2018-06-29 | Csl Ltd | Contaminant removal method |
US10053296B2 (en) | 2016-09-19 | 2018-08-21 | Asgco Manufacturing, Inc. | Return idler trainer |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3870801A (en) | 1968-08-09 | 1975-03-11 | Lever Brothers Ltd | Fluid aqueous protein compositions and food products prepared therefrom |
US3919044A (en) | 1973-03-28 | 1975-11-11 | Armour Pharma | Processes for concentrating and purifying viruses and viral antigens |
US3874999A (en) | 1973-10-31 | 1975-04-01 | American Cyanamid Co | Process for the purification of virus vaccine |
CA1099576A (en) | 1978-03-23 | 1981-04-21 | Chester D. Myers | Improved process for isolation of proteins |
US4473494A (en) | 1983-05-04 | 1984-09-25 | The United States Of America As Represented By The Secretary Of The Army | Preparation of stroma-free, non-heme protein-free hemoglobin |
US4684723A (en) * | 1985-09-11 | 1987-08-04 | Miles Laboratories, Inc. | Method of separating proteins from aqueous solutions |
JPH0720986B2 (ja) | 1985-10-07 | 1995-03-08 | 日本ケミカルリサ−チ株式会社 | 生理活性物質の製造法 |
AU605901B2 (en) | 1987-09-11 | 1991-01-24 | Ares Trading S.A. | Purification process |
RU1781355C (ru) * | 1990-04-23 | 1992-12-15 | В.П.Широбоков, Л.Я.Палиенко, А.И.Евтушенко, Л.А Коптюх, Ю.В.Загороднюк и К.Д Стеценко | Фильтрующий материал |
US5017292A (en) | 1990-05-10 | 1991-05-21 | Millipore Corporation | Membrane, process and system for isolating virus from solution |
US5076933A (en) | 1990-06-29 | 1991-12-31 | Coulter Corporation | Process and apparatus for removal of dna and viruses |
US5221483A (en) * | 1990-06-29 | 1993-06-22 | Coulter Corporation | Process and apparatus for removal of DNA, viruses and endotoxins |
SE9301582D0 (sv) | 1993-05-07 | 1993-05-07 | Kabi Pharmacia Ab | Purification of plasma proteins |
SE9500724D0 (sv) * | 1994-06-23 | 1995-02-24 | Pharmacia Ab | Filtrering |
-
1995
- 1995-02-24 SE SE9500724A patent/SE9500724D0/xx unknown
- 1995-06-22 WO PCT/SE1995/000777 patent/WO1996000237A1/en active IP Right Grant
- 1995-06-22 JP JP50306296A patent/JP3676370B2/ja not_active Expired - Fee Related
- 1995-06-22 PT PT95923651T patent/PT796269E/pt unknown
- 1995-06-22 US US08/750,664 patent/US6486306B1/en not_active Expired - Fee Related
- 1995-06-22 ES ES95923651T patent/ES2105992T3/es not_active Expired - Lifetime
- 1995-06-22 NZ NZ288789A patent/NZ288789A/en not_active IP Right Cessation
- 1995-06-22 MX MX9606639A patent/MX9606639A/es not_active IP Right Cessation
- 1995-06-22 DK DK95923651T patent/DK0796269T3/da active
- 1995-06-22 CA CA002192683A patent/CA2192683C/en not_active Expired - Fee Related
- 1995-06-22 AT AT95923651T patent/ATE212354T1/de not_active IP Right Cessation
- 1995-06-22 DE DE69525176T patent/DE69525176T2/de not_active Revoked
- 1995-06-22 DE DE0796269T patent/DE796269T1/de active Pending
- 1995-06-22 EP EP95923651A patent/EP0796269B1/en not_active Revoked
-
1996
- 1996-12-20 NO NO19965523A patent/NO320952B1/no not_active IP Right Cessation
- 1996-12-20 FI FI965145A patent/FI965145A0/fi not_active Application Discontinuation
-
1997
- 1997-11-28 GR GR970300038T patent/GR970300038T1/el unknown
-
2000
- 2000-02-23 US US09/511,953 patent/US6399357B1/en not_active Expired - Fee Related
-
2002
- 2002-11-26 US US10/304,902 patent/US20030191292A1/en not_active Abandoned
-
2005
- 2005-02-23 US US11/064,770 patent/US20050203285A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
ES2105992T2 (es) | 1997-11-01 |
DK0796269T3 (da) | 2002-05-06 |
NZ288789A (en) | 1997-12-19 |
ES2105992T3 (es) | 2002-09-16 |
AU682274B2 (en) | 1997-09-25 |
DE69525176D1 (de) | 2002-03-14 |
ES2105992T1 (es) | 1997-11-01 |
DE69525176T2 (de) | 2002-06-27 |
MX9606639A (es) | 1997-03-29 |
NO965523L (no) | 1996-12-20 |
SE9500724D0 (sv) | 1995-02-24 |
DE796269T1 (de) | 1998-01-02 |
FI965145A (fi) | 1996-12-20 |
US20030191292A1 (en) | 2003-10-09 |
CA2192683A1 (en) | 1996-01-04 |
GR970300038T1 (en) | 1997-11-28 |
EP0796269B1 (en) | 2002-01-23 |
US6399357B1 (en) | 2002-06-04 |
WO1996000237A1 (en) | 1996-01-04 |
JPH10502074A (ja) | 1998-02-24 |
FI965145A0 (fi) | 1996-12-20 |
US6486306B1 (en) | 2002-11-26 |
PT796269E (pt) | 2002-06-28 |
US20050203285A1 (en) | 2005-09-15 |
CA2192683C (en) | 2005-07-05 |
ATE212354T1 (de) | 2002-02-15 |
NO965523D0 (no) | 1996-12-20 |
EP0796269A1 (en) | 1997-09-24 |
JP3676370B2 (ja) | 2005-07-27 |
AU2813295A (en) | 1996-01-19 |
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Legal Events
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MM1K | Lapsed by not paying the annual fees |