NO20085422L - Bindingsproteiner for hepatocyttvekstfaktor (HGF) - Google Patents

Bindingsproteiner for hepatocyttvekstfaktor (HGF)

Info

Publication number
NO20085422L
NO20085422L NO20085422A NO20085422A NO20085422L NO 20085422 L NO20085422 L NO 20085422L NO 20085422 A NO20085422 A NO 20085422A NO 20085422 A NO20085422 A NO 20085422A NO 20085422 L NO20085422 L NO 20085422L
Authority
NO
Norway
Prior art keywords
hgf
binding proteins
growth factor
hepatocyte growth
activity
Prior art date
Application number
NO20085422A
Other languages
English (en)
Inventor
May Han
S Kirk Wright
Jr William M Winston
Lyne Breault
Jie Lin
Bijan Etemad-Gilbertson
Christine Knuehl
Jeno Gyuris
Original Assignee
Aveo Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aveo Pharmaceuticals Inc filed Critical Aveo Pharmaceuticals Inc
Publication of NO20085422L publication Critical patent/NO20085422L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Abstract

Foreliggende oppfinnelse tilveiebringer en familie av bindingsproteiner som binder og nøytraliserer aktiviteten av hepatocyttvekstfaktor (HGF), fortrinnsvis human HGF. Bindingsproteinene kan anvendes som diagnostiske og/eller terapeutiske midler. Når det gjelder deres terapeutiske aktivitet, kan bindingsproteinene anvendes for behandling av visse HGF-responderende forstyrrelser, f. eks. visse HGF- responderende tumorer.
NO20085422A 2006-06-02 2008-12-30 Bindingsproteiner for hepatocyttvekstfaktor (HGF) NO20085422L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US81071406P 2006-06-02 2006-06-02
US86046106P 2006-11-21 2006-11-21
PCT/US2007/012950 WO2007143098A2 (en) 2006-06-02 2007-06-01 Hepatocyte growth factor (hgf) binding proteins

Publications (1)

Publication Number Publication Date
NO20085422L true NO20085422L (no) 2009-02-27

Family

ID=38802082

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20085422A NO20085422L (no) 2006-06-02 2008-12-30 Bindingsproteiner for hepatocyttvekstfaktor (HGF)

Country Status (16)

Country Link
US (5) US7659378B2 (no)
EP (2) EP2380908A1 (no)
JP (2) JP4560582B2 (no)
KR (1) KR101196184B1 (no)
AR (1) AR061170A1 (no)
AT (1) ATE533787T1 (no)
AU (1) AU2007254853B2 (no)
BR (1) BRPI0712223A2 (no)
CA (1) CA2654019A1 (no)
ES (1) ES2378097T3 (no)
HK (1) HK1129394A1 (no)
IL (2) IL195038A0 (no)
MX (1) MX2008015138A (no)
NO (1) NO20085422L (no)
NZ (1) NZ573819A (no)
WO (1) WO2007143098A2 (no)

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Also Published As

Publication number Publication date
WO2007143098A8 (en) 2009-01-08
WO2007143098A2 (en) 2007-12-13
AU2007254853A1 (en) 2007-12-13
MX2008015138A (es) 2009-01-28
US20080038257A1 (en) 2008-02-14
JP2010246565A (ja) 2010-11-04
JP2009539348A (ja) 2009-11-19
KR20090026315A (ko) 2009-03-12
US20110236377A1 (en) 2011-09-29
AU2007254853B2 (en) 2011-11-17
EP2380908A1 (en) 2011-10-26
AR061170A1 (es) 2008-08-06
EP2029627A2 (en) 2009-03-04
ES2378097T3 (es) 2012-04-04
JP4560582B2 (ja) 2010-10-13
US7659378B2 (en) 2010-02-09
EP2029627B1 (en) 2011-11-16
US8268315B2 (en) 2012-09-18
NZ573819A (en) 2011-09-30
AU2007254853A2 (en) 2009-02-12
US8575318B2 (en) 2013-11-05
KR101196184B1 (ko) 2012-11-01
HK1129394A1 (en) 2009-11-27
ATE533787T1 (de) 2011-12-15
CA2654019A1 (en) 2007-12-13
BRPI0712223A2 (pt) 2012-07-10
US20140178934A1 (en) 2014-06-26
JP5528246B2 (ja) 2014-06-25
IL219655A0 (en) 2012-06-28
IL195038A0 (en) 2011-08-01
US20130203970A1 (en) 2013-08-08
US7935502B2 (en) 2011-05-03
WO2007143098A3 (en) 2008-06-12
US20100173361A1 (en) 2010-07-08

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