NO20083378L - Syntese av glukagon-lignende peptid - Google Patents

Syntese av glukagon-lignende peptid

Info

Publication number
NO20083378L
NO20083378L NO20083378A NO20083378A NO20083378L NO 20083378 L NO20083378 L NO 20083378L NO 20083378 A NO20083378 A NO 20083378A NO 20083378 A NO20083378 A NO 20083378A NO 20083378 L NO20083378 L NO 20083378L
Authority
NO
Norway
Prior art keywords
peptide
glucagon
synthesis
devised
new method
Prior art date
Application number
NO20083378A
Other languages
English (en)
Norwegian (no)
Inventor
Matthieu Giraud
Oleg Werbitzky
Stephane Varray
Carsten Meininghaus
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Publication of NO20083378L publication Critical patent/NO20083378L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/10—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using coupling agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
NO20083378A 2006-02-08 2008-08-04 Syntese av glukagon-lignende peptid NO20083378L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06002537 2006-02-08
PCT/EP2007/000198 WO2007090496A1 (en) 2006-02-08 2007-01-11 Synthesis of glucagon-like peptide

Publications (1)

Publication Number Publication Date
NO20083378L true NO20083378L (no) 2008-10-31

Family

ID=37697824

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20083378A NO20083378L (no) 2006-02-08 2008-08-04 Syntese av glukagon-lignende peptid

Country Status (19)

Country Link
US (2) US8445433B2 (de)
EP (1) EP1987052B1 (de)
JP (1) JP5199126B2 (de)
KR (1) KR101297942B1 (de)
CN (1) CN101379075B (de)
AT (1) ATE507235T1 (de)
AU (1) AU2007214088B2 (de)
BR (1) BRPI0707599A2 (de)
CA (1) CA2641053A1 (de)
DE (1) DE602007014184D1 (de)
DK (1) DK1987052T3 (de)
ES (1) ES2364982T3 (de)
IL (1) IL193134A (de)
MX (1) MX2008010136A (de)
NO (1) NO20083378L (de)
PT (1) PT1987052E (de)
TW (1) TWI404724B (de)
WO (1) WO2007090496A1 (de)
ZA (1) ZA200806690B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2205624B1 (de) * 2007-10-27 2016-09-07 Corden Pharma Colorado, Inc. Synthese eines insulinotropen peptids mithilfe von feststoff- und flüssigphasenkombinationsverfahren
MX2010006044A (es) * 2007-12-11 2010-06-23 Hoffmann La Roche Sintesis de peptidos insulinotropicos utilizando una combinacion de tecnicas en fase solida y en solucion.
EP2424888A2 (de) * 2009-05-01 2012-03-07 F. Hoffmann-La Roche AG Synthese insulinotroper peptide unter anwendung von fest- und flüssigphasenkombinationsverfahren
CN102250235A (zh) * 2011-06-23 2011-11-23 成都圣诺科技发展有限公司 奈西立肽的制备方法
GB201310921D0 (en) 2013-06-19 2013-07-31 Chemical & Biopharmaceutical Lab Of Patras S A Peptide-resin conjugate and use thereof
JP2017502003A (ja) * 2013-12-13 2017-01-19 メディミューン リミテッド プロテアーゼ耐性ペプチド
CN104017064B (zh) * 2014-06-13 2016-08-24 杭州阿诺生物医药科技股份有限公司 一种制备特立帕肽的方法
GR20140100479A (el) 2014-09-23 2016-05-05 Novetide, Ltd., Συνθεση λιραγλουτιδης
CN104356221B (zh) * 2014-10-24 2018-06-26 杭州阿诺生物医药科技股份有限公司 一种制备培西加南的方法
JP6991196B2 (ja) * 2016-03-23 2022-02-03 バッヘン・ホールディング・アクチエンゲゼルシャフト グルカゴン様ペプチドを製造するための方法
WO2019069274A1 (en) 2017-10-04 2019-04-11 Chemical & Biopharmaceutical Laboratories Of Patras S.A. PROCESS FOR THE PREPARATION OF A GLUCAGON-LIKE PEPTIDE
WO2020127476A1 (en) 2018-12-19 2020-06-25 Krka, D.D., Novo Mesto Pharmaceutical composition comprising glp-1 analogue
WO2020190757A1 (en) 2019-03-15 2020-09-24 Novetide Ltd. Improved processes for the preparation of semaglutide
WO2021123228A1 (en) 2019-12-18 2021-06-24 Krka, D.D., Novo Mesto Pharmaceutical composition comprising glp-1 analogue
CN115260313B (zh) 2019-12-31 2023-07-18 北京质肽生物医药科技有限公司 Glp-1和gdf15的融合蛋白以及其缀合物
CN115925994B (zh) 2020-09-30 2023-09-22 北京质肽生物医药科技有限公司 多肽缀合物和使用方法
CN114249808A (zh) * 2021-12-27 2022-03-29 杭州诺泰澳赛诺医药技术开发有限公司 一种Cagrilintide的合成方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3421303A1 (de) 1984-06-08 1985-12-12 Hoechst Ag, 6230 Frankfurt Salze aus 3-hydroxy-4-oxo-3,4-dihydro-1,2,3-benzotriazin und amino-verbindungen
US5574008A (en) * 1994-08-30 1996-11-12 Eli Lilly And Company Biologically active fragments of glucagon-like insulinotropic peptide
US6268343B1 (en) * 1996-08-30 2001-07-31 Novo Nordisk A/S Derivatives of GLP-1 analogs
SI1180121T1 (en) * 1999-05-17 2004-04-30 Conjuchem, Inc. Long lasting insulinotropic peptides
HUP0204281A3 (en) 2000-01-27 2007-03-28 Lilly Co Eli Process for sulubilizing glucagon-like peptide 1 (glp-1) compounds
US6969702B2 (en) * 2002-11-20 2005-11-29 Neuronova Ab Compounds and methods for increasing neurogenesis
TW200526254A (en) * 2003-09-19 2005-08-16 Novo Nordisk As Novel GLP-1 derivatives
RU2007134155A (ru) * 2005-03-18 2009-04-27 Ново Нордиск А/С (DK) Glp-1 соединения с увеличенным временем полужизни

Also Published As

Publication number Publication date
CN101379075B (zh) 2013-05-15
TWI404724B (zh) 2013-08-11
AU2007214088B2 (en) 2012-03-22
BRPI0707599A2 (pt) 2011-05-10
IL193134A (en) 2014-06-30
EP1987052B1 (de) 2011-04-27
ATE507235T1 (de) 2011-05-15
PT1987052E (pt) 2011-07-25
KR101297942B1 (ko) 2013-08-19
JP2009525997A (ja) 2009-07-16
US9040480B2 (en) 2015-05-26
CA2641053A1 (en) 2007-08-16
ZA200806690B (en) 2009-07-29
US20130324699A1 (en) 2013-12-05
JP5199126B2 (ja) 2013-05-15
WO2007090496A1 (en) 2007-08-16
EP1987052A1 (de) 2008-11-05
US20090292106A1 (en) 2009-11-26
US8445433B2 (en) 2013-05-21
DE602007014184D1 (de) 2011-06-09
TW200745157A (en) 2007-12-16
IL193134A0 (en) 2009-02-11
ES2364982T3 (es) 2011-09-20
CN101379075A (zh) 2009-03-04
MX2008010136A (es) 2008-12-19
AU2007214088A1 (en) 2007-08-16
KR20080100448A (ko) 2008-11-18
DK1987052T3 (da) 2011-08-15

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