DK1737889T3 - Fremgangsmåde til fastfase-peptidsyntese - Google Patents

Fremgangsmåde til fastfase-peptidsyntese

Info

Publication number
DK1737889T3
DK1737889T3 DK05796944.6T DK05796944T DK1737889T3 DK 1737889 T3 DK1737889 T3 DK 1737889T3 DK 05796944 T DK05796944 T DK 05796944T DK 1737889 T3 DK1737889 T3 DK 1737889T3
Authority
DK
Denmark
Prior art keywords
solid
peptide synthesis
phase peptide
phase
devised
Prior art date
Application number
DK05796944.6T
Other languages
English (en)
Inventor
Anne-Sophie Droz
Jasmine Schnidrig
Nicole Studer
Oleg Werbitzky
Stephane Varray
Corinne Wenger
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Application granted granted Critical
Publication of DK1737889T3 publication Critical patent/DK1737889T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/815—Protease inhibitors from leeches, e.g. hirudin, eglin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/042—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK05796944.6T 2004-10-19 2005-10-19 Fremgangsmåde til fastfase-peptidsyntese DK1737889T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04024812 2004-10-19
PCT/EP2005/011226 WO2006045503A1 (en) 2004-10-19 2005-10-19 Method for solid phase peptide synthesis

Publications (1)

Publication Number Publication Date
DK1737889T3 true DK1737889T3 (da) 2011-01-03

Family

ID=35427609

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05796944.6T DK1737889T3 (da) 2004-10-19 2005-10-19 Fremgangsmåde til fastfase-peptidsyntese

Country Status (11)

Country Link
US (2) USRE46830E1 (da)
EP (1) EP1737889B1 (da)
JP (1) JP4903709B2 (da)
CN (2) CN102225966B (da)
AT (1) ATE480561T1 (da)
DE (1) DE602005023429D1 (da)
DK (1) DK1737889T3 (da)
ES (1) ES2352204T3 (da)
IL (1) IL182698A (da)
PT (1) PT1737889E (da)
WO (1) WO2006045503A1 (da)

Families Citing this family (17)

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EP1805204A2 (en) * 2005-09-14 2007-07-11 Novetide Ltd. Process for production of bivalirudin
EP2057183A2 (en) * 2007-03-01 2009-05-13 Novetide Ltd. High purity peptides
US7582727B1 (en) 2008-07-27 2009-09-01 The Medicinces Company Pharmaceutical formulations of bivalirudin and processes of making the same
US7598343B1 (en) 2008-07-27 2009-10-06 The Medicines Company Pharmaceutical formulations of bivalirudin and processes of making the same
KR20110056536A (ko) * 2008-09-03 2011-05-30 시노팜 타이완 리미티드 프람린티드의 제조 방법
JP5730781B2 (ja) * 2008-12-29 2015-06-10 ロンザ・ブレーヌ・エスエーＬｏｎｚａ Ｂｒａｉｎｅ Ｓａ ビバリルジンの製造方法
CN101475631B (zh) * 2009-01-08 2011-08-17 苏州中科天马肽工程中心有限公司 比伐卢定的液相合成方法
US20110160431A1 (en) 2009-04-06 2011-06-30 Novetide, Ltd. Production of peptides containing poly-gly sequences using fmoc chemistry
CN101555274B (zh) * 2009-05-15 2013-08-21 海南双成药业股份有限公司 一种多肽固相合成比法卢定粗品的制备方法
WO2013042129A1 (en) 2011-09-23 2013-03-28 Natco Pharma Limited Improved process for preparation of bivalirudin
US9388212B2 (en) * 2013-02-21 2016-07-12 Chemical & Biopharmaceutical Laboratories Of Patras S.A. Solid phase peptide synthesis via side chain attachment
JP6382488B2 (ja) * 2013-02-21 2018-08-29 ケミカル アンド バイオファーマシューティカル ラボラトリーズ オブ パトラ エス．エー． 側鎖結合を介する固相ペプチド合成
GB201310921D0 (en) 2013-06-19 2013-07-31 Chemical & Biopharmaceutical Lab Of Patras S A Peptide-resin conjugate and use thereof
JPWO2016047794A1 (ja) * 2014-09-26 2017-09-28 株式会社カネカ 疎水性ペプチドの製造法
CN108383905A (zh) * 2016-12-30 2018-08-10 江苏金斯瑞生物科技有限公司 一种比伐卢定的制备方法
CN112111001B (zh) * 2019-06-19 2021-10-29 翰宇药业（武汉）有限公司 胸腺肽Tα-1的合成方法
JP2020138975A (ja) * 2020-05-18 2020-09-03 ケミカル アンド バイオファーマシューティカル ラボラトリーズ オブ パトラ エス．エー． 側鎖結合を介する固相ペプチド合成

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WO2006045503A1 (en) 2006-05-04
ES2352204T3 (es) 2011-02-16
EP1737889B1 (en) 2010-09-08
DE602005023429D1 (de) 2010-10-21
IL182698A0 (en) 2007-09-20
CN101094867A (zh) 2007-12-26
JP4903709B2 (ja) 2012-03-28
CN102225966B (zh) 2012-12-26
US20080287648A1 (en) 2008-11-20
IL182698A (en) 2013-11-28
ATE480561T1 (de) 2010-09-15
JP2008517018A (ja) 2008-05-22
USRE46830E1 (en) 2018-05-08
CN102225966A (zh) 2011-10-26
US7939629B2 (en) 2011-05-10
PT1737889E (pt) 2010-12-13
EP1737889A1 (en) 2007-01-03

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