NO20081818L - Arylsulfonylkromaner som 5-HT6-inhibitorer - indolylmaleimidderivater som protein kinaseinhibitorer - Google Patents
Arylsulfonylkromaner som 5-HT6-inhibitorer - indolylmaleimidderivater som protein kinaseinhibitorerInfo
- Publication number
- NO20081818L NO20081818L NO20081818A NO20081818A NO20081818L NO 20081818 L NO20081818 L NO 20081818L NO 20081818 A NO20081818 A NO 20081818A NO 20081818 A NO20081818 A NO 20081818A NO 20081818 L NO20081818 L NO 20081818L
- Authority
- NO
- Norway
- Prior art keywords
- inhibitors
- chromones
- arylsulfonyl
- protein kinase
- indolylmaleimide derivatives
- Prior art date
Links
- -1 Arylsulfonyl Chromones Chemical class 0.000 title 1
- 229940045988 antineoplastic drug protein kinase inhibitors Drugs 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 239000003909 protein kinase inhibitor Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 108091005435 5-HT6 receptors Proteins 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Abstract
Forbindelser med formel I: I hvor m, n, p, X, Ar, R1, R2, R3, R4 og R5 er som definert her. Det er beskrevet metoder for fremstilling av forbindelsene, samt anvendelsen av forbindelsene for behandling av 5-HT6-reseptor-medierte sykdommer. 1
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US73294005P | 2005-11-03 | 2005-11-03 | |
PCT/EP2006/067732 WO2007051735A1 (en) | 2005-11-03 | 2006-10-24 | Arylsulfonylchromans as 5-ht6 inhibitors indolylmaleimide derivatives as protein kinase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20081818L true NO20081818L (no) | 2008-06-19 |
Family
ID=37808173
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20081818A NO20081818L (no) | 2005-11-03 | 2008-04-15 | Arylsulfonylkromaner som 5-HT6-inhibitorer - indolylmaleimidderivater som protein kinaseinhibitorer |
Country Status (19)
Country | Link |
---|---|
US (1) | US7754759B2 (no) |
EP (1) | EP2027104B1 (no) |
JP (1) | JP2009514828A (no) |
KR (1) | KR100984897B1 (no) |
CN (1) | CN101300246A (no) |
AR (1) | AR056213A1 (no) |
AT (1) | ATE499355T1 (no) |
AU (1) | AU2006310612A1 (no) |
BR (1) | BRPI0618206A2 (no) |
CA (1) | CA2628173A1 (no) |
DE (1) | DE602006020351D1 (no) |
ES (1) | ES2359735T3 (no) |
IL (1) | IL190868A0 (no) |
NO (1) | NO20081818L (no) |
NZ (1) | NZ567285A (no) |
RU (1) | RU2008115032A (no) |
TW (1) | TWI327914B (no) |
WO (1) | WO2007051735A1 (no) |
ZA (1) | ZA200803422B (no) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8354548B2 (en) * | 2010-02-19 | 2013-01-15 | Bristol-Myers Squibb Company | Glycine chroman-6-sulfonamides for use as inhibitors of diacylglycerol lipase |
CN113200952B (zh) * | 2021-04-13 | 2023-03-10 | 江西师范大学 | 一种串联环化反应合成2-氨基-3,3-二氯代色满酮或2-氨基-3,3-二溴代色满酮的方法 |
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DE4102103A1 (de) | 1991-01-25 | 1992-08-20 | Bayer Ag | Substituierte benzoxazepine und benzthiazepine, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
US5817693A (en) * | 1991-11-05 | 1998-10-06 | Cousins; Russell Donovan | Endothelin receptor antagonists |
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US5374643A (en) * | 1992-09-11 | 1994-12-20 | E. R. Squibb & Sons, Inc. | Aryl urea (thiourea) and cyanoguanidine derivatives |
US5739135A (en) * | 1993-09-03 | 1998-04-14 | Bristol-Myers Squibb Company | Inhibitors of microsomal triglyceride transfer protein and method |
ATE183184T1 (de) | 1994-01-31 | 1999-08-15 | Pfizer | Neuroprotektive chroman verbindungen |
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US5663194A (en) * | 1995-07-25 | 1997-09-02 | Mewshaw; Richard E. | Chroman-2-ylmethylamino derivatives |
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TWI242011B (en) * | 1997-03-31 | 2005-10-21 | Eisai Co Ltd | 1,4-substituted cyclic amine derivatives |
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ES2144355B1 (es) | 1997-12-30 | 2001-01-01 | Ferrer Int | Compuestos derivados del cromeno. |
FR2778662B1 (fr) * | 1998-05-12 | 2000-06-16 | Adir | Nouveaux composes cycliques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
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ES2213407T3 (es) * | 1998-12-04 | 2004-08-16 | Takeda Chemical Industries, Ltd. | Derivados de benzofurano, procedimiento para su preparacion, y sus usos. |
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-
2006
- 2006-10-24 WO PCT/EP2006/067732 patent/WO2007051735A1/en active Application Filing
- 2006-10-24 EP EP06807516A patent/EP2027104B1/en active Active
- 2006-10-24 AT AT06807516T patent/ATE499355T1/de active
- 2006-10-24 RU RU2008115032/04A patent/RU2008115032A/ru not_active Application Discontinuation
- 2006-10-24 JP JP2008538331A patent/JP2009514828A/ja not_active Ceased
- 2006-10-24 AU AU2006310612A patent/AU2006310612A1/en not_active Abandoned
- 2006-10-24 CN CNA2006800410298A patent/CN101300246A/zh active Pending
- 2006-10-24 KR KR1020087013315A patent/KR100984897B1/ko not_active IP Right Cessation
- 2006-10-24 BR BRPI0618206-2A patent/BRPI0618206A2/pt not_active IP Right Cessation
- 2006-10-24 DE DE602006020351T patent/DE602006020351D1/de active Active
- 2006-10-24 CA CA002628173A patent/CA2628173A1/en not_active Abandoned
- 2006-10-24 ES ES06807516T patent/ES2359735T3/es active Active
- 2006-10-24 NZ NZ567285A patent/NZ567285A/en unknown
- 2006-10-31 TW TW095140241A patent/TWI327914B/zh active
- 2006-11-01 AR ARP060104782A patent/AR056213A1/es unknown
- 2006-11-03 US US11/592,685 patent/US7754759B2/en not_active Expired - Fee Related
-
2008
- 2008-04-14 IL IL190868A patent/IL190868A0/en unknown
- 2008-04-15 NO NO20081818A patent/NO20081818L/no not_active Application Discontinuation
- 2008-04-17 ZA ZA200803422A patent/ZA200803422B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
ES2359735T3 (es) | 2011-05-26 |
RU2008115032A (ru) | 2009-12-10 |
IL190868A0 (en) | 2008-11-03 |
ZA200803422B (en) | 2009-09-30 |
BRPI0618206A2 (pt) | 2011-08-23 |
US20070099908A1 (en) | 2007-05-03 |
TW200800163A (en) | 2008-01-01 |
TWI327914B (en) | 2010-08-01 |
KR20080074935A (ko) | 2008-08-13 |
ATE499355T1 (de) | 2011-03-15 |
DE602006020351D1 (en) | 2011-04-07 |
KR100984897B1 (ko) | 2010-10-01 |
NZ567285A (en) | 2010-06-25 |
CA2628173A1 (en) | 2007-05-10 |
US7754759B2 (en) | 2010-07-13 |
EP2027104A1 (en) | 2009-02-25 |
EP2027104B1 (en) | 2011-02-23 |
AR056213A1 (es) | 2007-09-26 |
AU2006310612A1 (en) | 2007-05-10 |
WO2007051735A1 (en) | 2007-05-10 |
JP2009514828A (ja) | 2009-04-09 |
CN101300246A (zh) | 2008-11-05 |
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