NO20073783L - Pyrrolidininhibitorer for IAP - Google Patents
Pyrrolidininhibitorer for IAPInfo
- Publication number
- NO20073783L NO20073783L NO20073783A NO20073783A NO20073783L NO 20073783 L NO20073783 L NO 20073783L NO 20073783 A NO20073783 A NO 20073783A NO 20073783 A NO20073783 A NO 20073783A NO 20073783 L NO20073783 L NO 20073783L
- Authority
- NO
- Norway
- Prior art keywords
- iap
- inhibitors
- pyrrolidine
- pyrrolidine inhibitors
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Abstract
Oppfinnelsen tilveiebringer nye inhibitorer av IAP, som er anvendbare som terapeutiske midler for behandling av kreft, hvor forbindelsene har den generelle formel (I): hvor A, Q, X1, X2, Y, R1, R2, R3, R4, R4' , R5, R6 og R6' er som beskrevet her.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63820204P | 2004-12-20 | 2004-12-20 | |
PCT/US2005/046161 WO2006069063A1 (en) | 2004-12-20 | 2005-12-19 | Pyrrolidine inhibitors of iap |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20073783L true NO20073783L (no) | 2007-09-19 |
NO339157B1 NO339157B1 (no) | 2016-11-14 |
Family
ID=36129810
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20073783A NO339157B1 (no) | 2004-12-20 | 2007-07-19 | Pyrrolidininhibitorer av IAP, og deres anvendelse i en fremgangsmåte for behandling av en sykdom eller tilstand assosiert med overekspresjon av en inhibitor av apoptose (IAP),spesielt av kreft, samt deres anvendelse ved fremstilling av et medikament. |
Country Status (19)
Country | Link |
---|---|
US (4) | US20060167066A1 (no) |
EP (1) | EP1836201B2 (no) |
JP (2) | JP5007235B2 (no) |
KR (2) | KR101278732B1 (no) |
CN (1) | CN101146803A (no) |
AT (1) | ATE477254T1 (no) |
AU (1) | AU2005319305B2 (no) |
CA (1) | CA2588921C (no) |
DE (1) | DE602005022936D1 (no) |
DK (1) | DK1836201T4 (no) |
EA (1) | EA019420B1 (no) |
ES (1) | ES2349110T5 (no) |
HK (1) | HK1109155A1 (no) |
IL (1) | IL183514A (no) |
MX (1) | MX2007007195A (no) |
NO (1) | NO339157B1 (no) |
NZ (1) | NZ589670A (no) |
WO (1) | WO2006069063A1 (no) |
ZA (1) | ZA200704910B (no) |
Families Citing this family (120)
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