NO20054897L - Farmasoytisk preparat inneholdende platinakompleks som aktiv substans og fremgangsmate for fremstilling derav - Google Patents
Farmasoytisk preparat inneholdende platinakompleks som aktiv substans og fremgangsmate for fremstilling deravInfo
- Publication number
- NO20054897L NO20054897L NO20054897A NO20054897A NO20054897L NO 20054897 L NO20054897 L NO 20054897L NO 20054897 A NO20054897 A NO 20054897A NO 20054897 A NO20054897 A NO 20054897A NO 20054897 L NO20054897 L NO 20054897L
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- platinum complex
- active substance
- pharmaceutically acceptable
- substance
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A61K31/282—Platinum compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2886—Dragees; Coated pills or tablets, e.g. with film or compression coating having two or more different drug-free coatings; Tablets of the type inert core-drug layer-inactive layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4891—Coated capsules; Multilayered drug free capsule shells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5015—Organic compounds, e.g. fats, sugars
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5052—Proteins, e.g. albumin
- A61K9/5057—Gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Det beskrives farmasøytiske preparater inneholdende platinakompleks med formel (I) som aktiv bestanddel, der A, A', B, B', X og X' har spesifikke betydninger, i blanding med minst en farmasøytisk akseptabel eksipient, der preparatet består av et granulat med partikler som er mindre enn 0,5 mm i størrelse, fremstilt ved våtgranulering av en blanding av platinakomplekset av tefravalent platina med formel (I) fiiktet med vann, minst ett nøyttalt sakkarid og minst ett nativt og/eller modifisert polysakkarid. Preparatet er inneholdt i en kapsel eUer en pose eUer er eventuelt presset tU tabletter mens overflaten av granulatet, kapselen eUer tablettene eventuelt er belagt med et sjikt av minst en farmasøytisk akseptabel substans som muhggjør enterosolvent oppløsning av den aktive substans kun i tarmene og/eller minst en farmasøytisk akseptabel substans som muliggjør konttollert fiigivning av den aktive substans. Det beskrives videre en fremgangsmåte for fremstilling av det farmasøytiske preparat.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CZ2003915A CZ296045B6 (cs) | 2003-03-31 | 2003-03-31 | Farmaceutická kompozice obsahující jako účinnou látku komplex čtyřmocné platiny a způsob její výroby |
CZ2004235A CZ2004235A3 (cs) | 2004-02-12 | 2004-02-12 | Farmaceutická kompozice obsahující jako účinnou látku platinový komplex a způsob výroby této kompozice |
PCT/CZ2004/000017 WO2004087126A1 (en) | 2003-03-31 | 2004-03-30 | Pharmaceutical composition containing platinum complex as active substance and method of manufacturing thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20054897L true NO20054897L (no) | 2005-10-24 |
Family
ID=33132424
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20054897A NO20054897L (no) | 2003-03-31 | 2005-10-24 | Farmasoytisk preparat inneholdende platinakompleks som aktiv substans og fremgangsmate for fremstilling derav |
Country Status (12)
Country | Link |
---|---|
US (1) | US20060063832A1 (no) |
EP (1) | EP1608358A1 (no) |
JP (1) | JP2006521300A (no) |
BR (1) | BRPI0408805A (no) |
CA (1) | CA2517120C (no) |
HR (1) | HRP20050902A2 (no) |
MX (1) | MXPA05010254A (no) |
NO (1) | NO20054897L (no) |
RS (1) | RS20050714A (no) |
RU (1) | RU2343913C2 (no) |
UA (1) | UA80872C2 (no) |
WO (1) | WO2004087126A1 (no) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002060446A1 (en) | 2001-01-29 | 2002-08-08 | Shionogi & Co., Ltd. | Medicinal preparation containing 5-methyl-1-phenyl-2-(1h)-pyridone as active ingredient |
CZ2004235A3 (cs) * | 2004-02-12 | 2005-08-17 | Pliva-Lachema A. S. | Farmaceutická kompozice obsahující jako účinnou látku platinový komplex a způsob výroby této kompozice |
CZ296459B6 (cs) * | 2004-09-14 | 2006-03-15 | Pliva-Lachema A. S. | Perorální farmaceutická kompozice pro cílený transport komplexu platiny do kolorektální oblasti, zpusob její prípravy a tato kompozice pro pouzití jako lécivo |
NZ591443A (en) * | 2005-09-22 | 2013-04-26 | Intermune Inc | Granule formation of pirfenidone and pharmaceutically acceptable excipients |
CZ300590B6 (cs) * | 2006-06-20 | 2009-06-24 | Pliva - Lachema A. S. | Farmaceutická kompozice pro injekcní podání |
EP2223683B1 (en) * | 2007-12-27 | 2014-06-18 | Taiho Pharmaceutical Co., Ltd. | Oral particulate antitumor preparation |
AU2010210593B2 (en) * | 2009-02-04 | 2015-09-03 | The Brigham And Women's Hospital, Inc. | Nanoscale platinum compounds and methods of use thereof |
MX2018006953A (es) | 2015-12-09 | 2019-05-16 | Univ Wien Med | Compuestos de platino funcionalizados con monomaleimida para la terapia del cancer. |
CA2937365C (en) | 2016-03-29 | 2018-09-18 | F. Hoffmann-La Roche Ag | Granulate formulation of 5-methyl-1-phenyl-2-(1h)-pyridone and method of making the same |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4302446A (en) * | 1979-10-02 | 1981-11-24 | Bristol-Myers Company | Pharmaceutical compositions |
JPS5970614A (ja) * | 1982-10-14 | 1984-04-21 | Asahi Chem Ind Co Ltd | 微量主薬系湿式固形製剤方法 |
US5240954A (en) * | 1985-06-25 | 1993-08-31 | Glaxo Group Limited | Medicaments |
US5256653A (en) * | 1987-02-19 | 1993-10-26 | Henkel Kommanditgesellschaft Auf Aktien | Pharmaceutical preparations containing platinum complexes/phosphonic acid liquid and processes for their use |
FI905018A0 (fi) * | 1989-10-17 | 1990-10-12 | Bristol Myers Squibb Co | I vatten och loesningsmedel loesliga axiala hydroxi-och mono- och dikarboxylsyraderivat med stor tumoeraktivitet. |
IT1241417B (it) * | 1990-03-06 | 1994-01-14 | Vectorpharma Int | Composizioni terapeutiche a rilascio controllato di farmaci supportatisu polimeri reticolati e rivestiti con film polimerici,e loro processodi preparazione |
IT1246382B (it) * | 1990-04-17 | 1994-11-18 | Eurand Int | Metodo per la cessione mirata e controllata di farmaci nell'intestino e particolarmente nel colon |
FR2729857B1 (fr) * | 1995-01-27 | 1997-04-04 | Rhone Poulenc Chimie | Compositions pharmaceutiques sous forme de comprimes a liberation prolongee a base de granules en polysaccharides de haut poids moleculaire |
JPH10265380A (ja) * | 1997-03-17 | 1998-10-06 | Bristol Myers Squibb Co | 抗ガン剤 |
CZ288912B6 (cs) * | 1998-05-27 | 2001-09-12 | Lachema, A. S. | Komplex platiny v oxidačním čísle IV, způsob přípravy tohoto komplexu, tento komplex jako léčivo a farmaceutická kompozice tento komplex obsahující |
KR100317473B1 (ko) * | 1999-05-11 | 2001-12-22 | 이계호 | 신규의 백금(iv)착제 및 그 제조방법 |
JP2001347153A (ja) * | 2000-06-12 | 2001-12-18 | Asahi Kasei Corp | 錠剤の製造方法 |
-
2004
- 2004-03-30 BR BRPI0408805-0A patent/BRPI0408805A/pt not_active IP Right Cessation
- 2004-03-30 JP JP2006504221A patent/JP2006521300A/ja active Pending
- 2004-03-30 US US10/549,296 patent/US20060063832A1/en not_active Abandoned
- 2004-03-30 CA CA2517120A patent/CA2517120C/en not_active Expired - Fee Related
- 2004-03-30 RS YUP-2005/0714A patent/RS20050714A/sr unknown
- 2004-03-30 UA UAA200510188A patent/UA80872C2/uk unknown
- 2004-03-30 WO PCT/CZ2004/000017 patent/WO2004087126A1/en active Application Filing
- 2004-03-30 RU RU2005133428/15A patent/RU2343913C2/ru not_active IP Right Cessation
- 2004-03-30 MX MXPA05010254A patent/MXPA05010254A/es unknown
- 2004-03-30 EP EP04724245A patent/EP1608358A1/en not_active Withdrawn
-
2005
- 2005-10-17 HR HR20050902A patent/HRP20050902A2/hr not_active Application Discontinuation
- 2005-10-24 NO NO20054897A patent/NO20054897L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
RU2343913C2 (ru) | 2009-01-20 |
MXPA05010254A (es) | 2006-02-22 |
US20060063832A1 (en) | 2006-03-23 |
HRP20050902A2 (en) | 2005-12-31 |
UA80872C2 (uk) | 2007-11-12 |
RS20050714A (sr) | 2008-04-04 |
RU2005133428A (ru) | 2006-05-10 |
BRPI0408805A (pt) | 2006-03-28 |
EP1608358A1 (en) | 2005-12-28 |
CA2517120A1 (en) | 2004-10-14 |
WO2004087126A1 (en) | 2004-10-14 |
CA2517120C (en) | 2012-09-18 |
AU2004226898A1 (en) | 2004-10-14 |
JP2006521300A (ja) | 2006-09-21 |
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Legal Events
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |