NO20015991L - Bicykliske polyaminosyre-metallkomplekser, fremgangsmåter for fremstilling av disse og deres anvendelse ved medisinsk avbildning - Google Patents

Bicykliske polyaminosyre-metallkomplekser, fremgangsmåter for fremstilling av disse og deres anvendelse ved medisinsk avbildning

Info

Publication number
NO20015991L
NO20015991L NO20015991A NO20015991A NO20015991L NO 20015991 L NO20015991 L NO 20015991L NO 20015991 A NO20015991 A NO 20015991A NO 20015991 A NO20015991 A NO 20015991A NO 20015991 L NO20015991 L NO 20015991L
Authority
NO
Norway
Prior art keywords
medical imaging
bicyclic
processes
preparation
metal complexes
Prior art date
Application number
NO20015991A
Other languages
English (en)
Other versions
NO321121B1 (no
NO20015991D0 (no
Inventor
Marc Port
Original Assignee
Guerbet Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Guerbet Sa filed Critical Guerbet Sa
Publication of NO20015991D0 publication Critical patent/NO20015991D0/no
Publication of NO20015991L publication Critical patent/NO20015991L/no
Publication of NO321121B1 publication Critical patent/NO321121B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polyamides (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
NO20015991A 1999-06-09 2001-12-07 Bicykliske polyaminosyre-metallkomplekser, fremgangsmater for fremstilling av disse og deres anvendelse ved medisinsk avbildning NO321121B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9907283A FR2794744B1 (fr) 1999-06-09 1999-06-09 Complexes metalliques de polyaminoacides bicycliques, leur procede de preparation et leur application en imagerie medicale
PCT/FR2000/001591 WO2000075141A1 (fr) 1999-06-09 2000-06-08 Complexes metalliques de polyaminoacides bicycliques, leur procede de preparation et leur application en imagerie medicale

Publications (3)

Publication Number Publication Date
NO20015991D0 NO20015991D0 (no) 2001-12-07
NO20015991L true NO20015991L (no) 2002-02-06
NO321121B1 NO321121B1 (no) 2006-03-20

Family

ID=9546571

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20015991A NO321121B1 (no) 1999-06-09 2001-12-07 Bicykliske polyaminosyre-metallkomplekser, fremgangsmater for fremstilling av disse og deres anvendelse ved medisinsk avbildning

Country Status (22)

Country Link
US (1) US6440956B1 (no)
EP (1) EP1183255B1 (no)
JP (1) JP4719391B2 (no)
KR (1) KR20020008218A (no)
CN (1) CN1196702C (no)
AT (1) ATE233762T1 (no)
AU (1) AU5540400A (no)
BR (1) BR0011436A (no)
CA (1) CA2376497C (no)
DE (1) DE60001564T2 (no)
DK (1) DK1183255T3 (no)
ES (1) ES2188556T3 (no)
FR (1) FR2794744B1 (no)
HU (1) HU227966B1 (no)
IL (2) IL146304A0 (no)
MX (1) MXPA01011439A (no)
NO (1) NO321121B1 (no)
PL (1) PL216974B1 (no)
PT (1) PT1183255E (no)
RU (1) RU2232763C2 (no)
TR (1) TR200103525T2 (no)
WO (1) WO2000075141A1 (no)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI20011706A1 (it) * 2001-08-03 2003-02-03 Bracco Imaging Spa Agenti di contrasto radiografici ionici e non ionici, utilizzabili per l'indagine diagnostica combinata tramite raggi-x e risonanza magnetic
US8518373B2 (en) 2001-08-03 2013-08-27 Bracco Imaging Spa Ionic and non-ionic radiographic contrast agents for use in combined X-ray and nuclear magnetic resonance diagnostics
FR2836916B1 (fr) * 2002-03-05 2004-06-11 Guerbet Sa Oligomeres de chelates de gadolinium, leur application comme produits de contraste en imagerie par resonance magnetique et leurs intermediaires de synthese
DE10307759B3 (de) * 2003-02-19 2004-11-18 Schering Ag Trimere makrocyclisch substituierte Benzolderivate, deren Herstellung und Verwendung als Kontrastmittel sowie diese enthaltende pharmazeutische Mittel
JP2004307356A (ja) * 2003-04-02 2004-11-04 Hamamatsu Kagaku Gijutsu Kenkyu Shinkokai 新規なデンドリマーおよび造影剤
FR2856689A1 (fr) * 2003-06-25 2004-12-31 Guerbet Sa Composes specifiques a forte relaxivite
FR2857967B1 (fr) * 2003-07-25 2015-04-24 Centre Nat Rech Scient Complexes de lanthanide, leur preparation et leurs utilisations
FR2867473B1 (fr) * 2004-03-12 2006-06-23 Guerbet Sa Compose de porphyrines et utilisation a haut champ en irm
CN1993357B (zh) 2004-07-02 2011-10-19 伯拉考成像股份公司 用于磁共振成像(mri)的含有具有多羟基化取代基的螯合部分的高弛豫造影剂
FR2875410B1 (fr) * 2004-09-23 2012-11-16 Guerbet Sa Composes de diagnostique pour le ciblage de recpteur a chimiokines
CN100355806C (zh) * 2005-03-04 2007-12-19 华东师范大学 端氨基嵌段聚氧乙烯改性的钆配合物及其合成方法
FR2883562B1 (fr) * 2005-03-24 2009-02-27 Guerbet Sa Chelates lipophiles et leur utilisation en imagerie
US8986650B2 (en) 2005-10-07 2015-03-24 Guerbet Complex folate-NOTA-Ga68
JP5368099B2 (ja) * 2005-10-07 2013-12-18 ゲルベ ガリウムと錯体形成することが可能なシグナル部分にカップリングされた、生物学的標的の認識のための部分を含んでなる化合物
FR2891830B1 (fr) * 2005-10-07 2011-06-24 Guerbet Sa Composes a chaines aminoalcools courtes et complexes metalliques pour l'imagerie medicale
FR2914304B1 (fr) * 2007-03-28 2012-11-16 Guerbet Sa Composes pour le diagnostic de maladies liees a l'expression de vcam.
FR2914303A1 (fr) * 2007-03-28 2008-10-03 Guerbet Sa Composes pour le diagnostic de l'apoptose.
DE102007058220A1 (de) 2007-12-03 2009-06-04 Bayer Schering Pharma Aktiengesellschaft Dimere macrocyclisch substituierte Benzolderivate
FR2942227B1 (fr) 2009-02-13 2011-04-15 Guerbet Sa Utilisation de tampons pour la complexation de radionucleides
IN2012DN02586A (no) * 2009-09-28 2015-08-28 Univ Kentucky Res Found
CA2909919C (fr) 2013-04-26 2022-07-12 Guerbet Formulation de produit de contraste et son procede de preparation associe
GB201610738D0 (en) * 2016-06-20 2016-08-03 Ge Healthcare As Chelate compounds
CA3044877A1 (en) 2016-11-28 2018-05-31 Bayer Pharma Aktiengesellschaft High relaxivity gadolinium chelate compounds for use in magnetic resonance imaging
ES2813077T3 (es) * 2016-12-21 2021-03-22 Ge Healthcare As Compuestos quelatos de manganeso basados en macrociclo de tetraazabiciclo adecuados como agentes de imagen de IRM
EP3728168B1 (en) * 2017-12-20 2022-03-30 General Electric Company Anionic chelate compounds
ES2841070T3 (es) 2018-08-06 2021-07-07 Bracco Imaging Spa Agentes de contraste basados en PCTA que comprenden gadolinio
JP7520007B2 (ja) 2018-11-23 2024-07-22 バイエル アクチェンゲゼルシャフト 造影剤の製剤およびその調製方法
FR3091873B1 (fr) 2019-01-17 2020-12-25 Guerbet Sa Complexe de gadolinium et d’un ligand chelateur derive de pcta diastereoisomeriquement enrichi et procede de preparation et de purification
US11370804B2 (en) 2019-01-17 2022-06-28 Guerbet Complex of gadolinium and a chelating ligand derived from a diastereoisomerically enriched PCTA and preparation and purification process
US11426470B2 (en) 2019-01-17 2022-08-30 Guerbet Complex of gadolinium and a chelating ligand derived of a diastereoisomerically enriched PCTA and synthesis method
FR3091872B1 (fr) * 2019-01-17 2020-12-25 Guerbet Sa Complexe de gadolinium et d’un ligand chelateur derive de pcta diastereoisomeriquement enrichi et procede de synthese
FI4143153T3 (fi) * 2020-07-16 2023-12-20 Guerbet Sa Menetelmä 2-bromiglutaarihapon diesterien synteesiä varten
CN115722276B (zh) * 2022-11-15 2024-06-18 江苏美亚科泽过滤技术有限公司 一种粒状多效吸附剂组合物及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4001655A1 (de) * 1990-01-18 1991-07-25 Schering Ag 6-ring enthaltende makrocyclische tetraaza-verbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
DE3825040A1 (de) * 1988-07-20 1990-01-25 Schering Ag, 13353 Berlin 5- oder 6-ring- enthaltende makrocyclische polyaza-verbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
FR2644785B1 (fr) * 1989-03-24 1991-07-05 Guerbet Sa Nouveaux ligands macrocycliques azotes, procede de preparation, complexes metalliques formes par ces ligands et composition de diagnostic les contenant
US5554748A (en) * 1989-04-07 1996-09-10 Nycomed Salutar, Inc. Adducts of macrocyclic chelants
HUT67602A (en) * 1991-12-10 1995-04-28 Dow Chemical Co Process for producing bicyclo-polyaza-macrocyclo-carboxylic acid complexes, their conjugates and contrast materials containing them
FR2736051B3 (fr) * 1995-06-29 1997-09-26 Guerbet Sa Complexes metalliques de polyaminoacides, leur procede de preparation et leur utilisation en imagerie diagnostique

Also Published As

Publication number Publication date
FR2794744A1 (fr) 2000-12-15
CA2376497C (fr) 2009-10-20
FR2794744B1 (fr) 2001-09-21
HUP0201468A3 (en) 2010-01-28
US6440956B1 (en) 2002-08-27
MXPA01011439A (es) 2002-06-04
NO321121B1 (no) 2006-03-20
IL146304A0 (en) 2002-07-25
CA2376497A1 (fr) 2000-12-14
CN1354751A (zh) 2002-06-19
JP2003501430A (ja) 2003-01-14
WO2000075141A1 (fr) 2000-12-14
EP1183255B1 (fr) 2003-03-05
NO20015991D0 (no) 2001-12-07
JP4719391B2 (ja) 2011-07-06
PL216974B1 (pl) 2014-05-30
RU2232763C2 (ru) 2004-07-20
DK1183255T3 (da) 2003-06-02
AU5540400A (en) 2000-12-28
TR200103525T2 (tr) 2002-05-21
HU227966B1 (en) 2012-07-30
PL352483A1 (en) 2003-08-25
DE60001564D1 (de) 2003-04-10
EP1183255A1 (fr) 2002-03-06
ATE233762T1 (de) 2003-03-15
DE60001564T2 (de) 2003-12-11
ES2188556T3 (es) 2003-07-01
HUP0201468A2 (en) 2002-08-28
KR20020008218A (ko) 2002-01-29
CN1196702C (zh) 2005-04-13
IL146304A (en) 2006-04-10
PT1183255E (pt) 2003-06-30
BR0011436A (pt) 2002-03-05

Similar Documents

Publication Publication Date Title
NO20015991L (no) Bicykliske polyaminosyre-metallkomplekser, fremgangsmåter for fremstilling av disse og deres anvendelse ved medisinsk avbildning
HUP0400231A3 (en) Methods and pharmaceutical compositions for immune deception, particularly useful in the treatment of cancer
HK1050860A1 (en) Nordihydroguaiaretic derivatives for use in treatment of tumors
MXPA03007140A (es) Derivados de carbolina.
PL370029A1 (en) 2-amino-4-heteroarylaminopyrimidine derivatives for use in the treatment of cancer
MY135766A (en) Quinolinones and naphthyridinones for treating inflammatory diseases
MY138239A (en) Nitrogen containing heterobicycles as factor xa inhibitors
JO2311B1 (en) Alkyl inhibitors Ariel phosphodiesterase-4
SG148031A1 (en) Use of cci-779 as an antineoplastic agent
ATE304358T1 (de) (s,s)-reboxetin zur behandlung von migränekopfschmerzen
WO2004089296A3 (en) Improved inhibitors for the soluble epoxide hydrolase
DE60216233D1 (en) Carbolinderivate
ZA200000523B (en) Process for the treatment of steel work gases.
MXPA03008582A (es) Agentes y metodos para tratamiento de cancer.
ZA200400313B (en) Use of BIBN4096 in combination with other antimigraine drugs for the treatment of migraine.
WO2002013874A8 (de) Verwendung von perfluoralkylhaltigen metallkomplexen als kontrastmittel im mr-imaging zur darstellung von plaques, tumoren und nekrosen
TR200103125T2 (tr) Otizmin iyileştirilmesinde kullanıma yönelik antikonvülsan türevleri.
HUP0204208A2 (hu) Pruritus kezelésére szolgáló külsőleges gyógyszerkészítmény
MXPA04000272A (es) Derivados de 4-aminociclohexanol sustituidos.
IL139144A0 (en) Mycobacterial inhibitors
WO2000069841A3 (en) Benzofuranylaminoalcohols
UA33359A (uk) Спосіб доступу до пухлин орбіти
DE60004819D1 (de) 10-formyltetrahydrofolate dehydrogenase als therapeutischen mittel
IL160412A0 (en) Methods and pharmaceutical compositions for immune deception, particularly in the treatment of cancer
UA32146A (uk) Спосіб оцінки ефективності лікування пародонтита

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees