NO160576C - Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive karboksylsyrederivater. - Google Patents

Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive karboksylsyrederivater.

Info

Publication number
NO160576C
NO160576C NO850154A NO850154A NO160576C NO 160576 C NO160576 C NO 160576C NO 850154 A NO850154 A NO 850154A NO 850154 A NO850154 A NO 850154A NO 160576 C NO160576 C NO 160576C
Authority
NO
Norway
Prior art keywords
preparation
carboxylic acid
acid derivatives
new therapeutic
therapeutic active
Prior art date
Application number
NO850154A
Other languages
English (en)
Other versions
NO850154L (no
NO160576B (no
Inventor
John Gerald Gleason
Carl David Perchonock
Original Assignee
Smithkline Beckman Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beckman Corp filed Critical Smithkline Beckman Corp
Publication of NO850154L publication Critical patent/NO850154L/no
Publication of NO160576B publication Critical patent/NO160576B/no
Publication of NO160576C publication Critical patent/NO160576C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/18Radicals substituted by singly bound hetero atoms other than halogen by sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/22Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/38Heterocyclic compounds having sulfur as a ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C321/00Thiols, sulfides, hydropolysulfides or polysulfides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/56Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/29Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
    • C07C45/298Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with manganese derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/44Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reduction and hydrolysis of nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/62Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/70Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
    • C07C45/71Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/52Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/542Alkylated benzaldehydes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/52Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/546Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings polycyclic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/52Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/548Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings having unsaturation outside the six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/52Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/55Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00Compounds having —CHO groups
    • C07C47/52Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/86Ketones containing a keto group bound to a six-membered aromatic ring containing —CHO groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO850154A 1984-01-19 1985-01-14 Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive karboksylsyrederivater. NO160576C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US57202184A 1984-01-19 1984-01-19
US63050084A 1984-07-13 1984-07-13

Publications (3)

Publication Number Publication Date
NO850154L NO850154L (no) 1985-07-22
NO160576B NO160576B (no) 1989-01-23
NO160576C true NO160576C (no) 1989-05-03

Family

ID=27075709

Family Applications (1)

Application Number Title Priority Date Filing Date
NO850154A NO160576C (no) 1984-01-19 1985-01-14 Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive karboksylsyrederivater.

Country Status (15)

Country Link
EP (1) EP0168902B1 (no)
KR (1) KR900000683B1 (no)
AU (1) AU571635B2 (no)
CA (1) CA1243035A (no)
DE (1) DE3560717D1 (no)
DK (1) DK21085A (no)
ES (1) ES8609230A1 (no)
FI (1) FI79698C (no)
GR (1) GR850106B (no)
HU (1) HU195638B (no)
IL (1) IL74068A (no)
NO (1) NO160576C (no)
NZ (1) NZ210839A (no)
PT (1) PT79835B (no)
ZW (1) ZW1085A1 (no)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1276937C (en) * 1985-04-19 1990-11-27 Smith Kline & French Canada Ltd. Leukotriene antagonists
US4871771A (en) * 1988-02-04 1989-10-03 Smithkline Beckman Corporation Leukotriene antagonists

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL277345A (no) * 1961-04-17 1900-01-01
FR2468362A1 (fr) * 1978-07-12 1981-05-08 Oreal Compositions cosmetiques a base de dithioethers pour le traitement de l'etat gras des cheveux et de la peau, nouveaux composes et leur procede d'obtention
US4269731A (en) * 1979-08-27 1981-05-26 Argus Chemical Corporation Antimony mercaptocarboxylic acid ester stabilizers for polyvinyl chloride resin compositions and process

Also Published As

Publication number Publication date
DK21085D0 (da) 1985-01-17
PT79835A (en) 1985-02-01
CA1243035A (en) 1988-10-11
HUT37748A (en) 1986-02-28
FI850226L (fi) 1985-07-20
DE3560717D1 (en) 1987-11-05
DK21085A (da) 1985-07-20
NO850154L (no) 1985-07-22
HU195638B (en) 1988-06-28
PT79835B (en) 1986-10-28
ES8609230A1 (es) 1986-07-16
GR850106B (no) 1985-05-16
KR850005407A (ko) 1985-08-26
FI79698C (fi) 1990-02-12
AU3777985A (en) 1985-08-01
EP0168902A1 (en) 1986-01-22
EP0168902B1 (en) 1987-09-30
FI850226A0 (fi) 1985-01-17
KR900000683B1 (ko) 1990-02-03
FI79698B (fi) 1989-10-31
IL74068A (en) 1988-08-31
ZW1085A1 (en) 1985-04-24
NZ210839A (en) 1987-10-30
AU571635B2 (en) 1988-04-21
NO160576B (no) 1989-01-23
ES539566A0 (es) 1986-07-16

Similar Documents

Publication Publication Date Title
NO162862C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktivt resinat av en substituert karboksylsyre.
NO170480C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive fenoksyeddiksyre-derivater
NO159089C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive glutarimidderivater.
NO167142C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive heterocykliske derivater.
NO864425D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive heterocyklyloksoftalazinyl-eddiksyre-derivater.
NO851949L (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive aminotetralinderivater.
NO871879D0 (no) Fremgangsmaate for fremstilling av nye, terapeutisk aktive heterocykliske forbindelser.
NO164097C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 2-(n-substituert-guanidino)-4-hetero-aryl-tiazol-derivater.
NO154426C (no) Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive trans-3-(4-okso-4h-kinazolin-3-yl)-2-propensyrederivater.
NO158534C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive fenoksyalkylkarboksylsyrederivater.
NO152005C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive karboksylsyrederivater
NO162155C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive vinylkarbonoksylsyrederivater.
NO165400C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive cefemforbindelser.
NO164897C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive oxazolidinonderivater.
NO165545C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive nye oksadiazolimidazo-benzodiazepinderivater.
NO168041C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive retinsyreestere av erytromycin.
NO165679C (no) Analogifremgangsmaate for fremstilling av nye, terapeutiskvirksomme androstan-17beta-karboksyl-syreestere.
NO164020C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive fenetanolaminderivater.
NO161313C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive fluorallylaminderivater.
NO891114L (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive arakidonsyre-derivater.
NO165635C (no) Analogifremgangsmaate for fremstilling av nye terapeutisk aktive kinolinderivater.
NO171108C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 3-desmetyl-mevalonsyrederivater
NO870482D0 (no) Fremgangsmaate ved fremstilling av nye karboksylsyreamider.
NO159590C (no) Analogifremgangsm te for fremstilling av terapeutisk aktive fenyleddiksyre-derivater.
NO164243C (no) Analogifremgangsmaate for fremstilling av nye terapeutisk aktive 16,17-acetalsubstituerte pregnan-21-oinsyrederivater