NO160576B - Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive karboksylsyrederivater. - Google Patents
Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive karboksylsyrederivater. Download PDFInfo
- Publication number
- NO160576B NO160576B NO850154A NO850154A NO160576B NO 160576 B NO160576 B NO 160576B NO 850154 A NO850154 A NO 850154A NO 850154 A NO850154 A NO 850154A NO 160576 B NO160576 B NO 160576B
- Authority
- NO
- Norway
- Prior art keywords
- pin
- land side
- preparation
- carboxylic acid
- acid derivatives
- Prior art date
Links
- 150000001732 carboxylic acid derivatives Chemical class 0.000 title 1
- 230000001225 therapeutic effect Effects 0.000 title 1
- 238000005096 rolling process Methods 0.000 claims description 3
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/18—Radicals substituted by singly bound hetero atoms other than halogen by sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/22—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of hydropolysulfides or polysulfides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
- C07C45/29—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups
- C07C45/298—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of hydroxy groups with manganese derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/44—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reduction and hydrolysis of nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/56—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/62—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by hydrogenation of carbon-to-carbon double or triple bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/70—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form
- C07C45/71—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction with functional groups containing oxygen only in singly bound form being hydroxy groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
- C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
- C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/542—Alkylated benzaldehydes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/546—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings polycyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/548—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings having unsaturation outside the six-membered aromatic rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/55—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing halogen
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C47/00—Compounds having —CHO groups
- C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
- C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/86—Ketones containing a keto group bound to a six-membered aromatic ring containing —CHO groups
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Description
Fullmektig: Siv. ing. Erik Bugge, Uranienborg terasse 19, Oslo
Plog med innstillbar veltefjel.
Denne oppfinnelse vedrører en plog med innstillbar veltefjel, nærmere bestemt av den art som er utstyrt med et stag som strekker seg mellom veltefjelens bakre del og landsiden og ved hjelp av hvilket veltefjelens stilling i forhold til landsiden kan varieres.
Hensikten med oppfinnelsen er å sikre en enkel og på-litelig innstilling av veltefjelen under pløyning slik at den øn-skede legging av plogfuren oppnås.
Plogen ifølge oppfinnelsen utmerker seg i det vesent-lige ved at staget er forbundet med veltefjelen eller landsiden ved hjelp av et festeorgan av i og for seg kjent art som har en sirkulær tapp som opptas i en sirkulær åpning i staget og er dreibar i forhold til veltefjelen respektiv landsiden om en med tappens senterlinje eksentrisk akse, således at ved dreining av festeorganet endres avstanden mellom stagets festepunkter hvorved den nevnte stilling av veltefjelen varieres.
Oppfinnelsen skal forklares nærmere ved hjelp av tegningen, hvor fig. 1 viser ploglegemet i perspektiv, og fig. 2 den ene ende av staget og eksenteren i større skala.
I fig. 1 betegnes plogåsen med 1 og ploglegemet med skjæret 2, landsiden 3 og veltefjelen 4. De sistnevnte er forbundet med et stag 5 som er festet til landsiden med en bolt 6. Ved den motsat-te ende er staget 5 forsynt med et rundt hull 6, som griper om en tapp 7 på et festeorgan 8. Dette har et hull 9, som er eksentrisk i forhold til tappen 7 før befestigelse i veltefjelen k ved hjelp av en bolt 10. Festeorganet 8 har en ribbe 11 for .dreining ved hjelp av et passende verktøy i forhold til bolten 10.
Det vil sees at dreining av festeorganet 8, således at tappens 7 sentrum flyttes utad, medfører at veltefjelen 4 trekkes nærmere landsiden 3, mens dreining av festeorganet i motsatt retning forskyver veltefjelens ytre del lengre bort fra landsiden 3. Her-ved fåes et forholdsvis vidstrakt område av innstillinger for veltef jelen 4, såfedes at dens stilling på en enkel måte kan tilpasses således at en ønsket legging av plogfuren kan erholdes.
Claims (1)
- i Plog utstyrt med et stag som strekker seg mellom veltef je-li lens CO bakre del og landsiden (3) og ved hjelp av hvilket veltefjelens (4) stilling i forhold til landsiden (3) kan varieres, kar a k' terisert ved at staget (5) er forbundet med veltef jelen (4) eller landsiden (3) ved hjelp av et festeorgan (8) av i og for seg kjent art som har en sirkulær tapp (7), som opptas i en sirkulær åpning (6) i. staget og er dreibar i forhold til veltef jelen respektiv landsiden om en med tappens senterlinje eksentrisk akse, således at ved dreining av festeorganet (8) endres avstanden mellom stagets (S) festepunkter hvorved den nevnte stilliig av veltef jelen varieres. ^...
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US57202184A | 1984-01-19 | 1984-01-19 | |
US63050084A | 1984-07-13 | 1984-07-13 |
Publications (3)
Publication Number | Publication Date |
---|---|
NO850154L NO850154L (no) | 1985-07-22 |
NO160576B true NO160576B (no) | 1989-01-23 |
NO160576C NO160576C (no) | 1989-05-03 |
Family
ID=27075709
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO850154A NO160576C (no) | 1984-01-19 | 1985-01-14 | Analogifremgangsmaate ved fremstilling av nye terapeutisk aktive karboksylsyrederivater. |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0168902B1 (no) |
KR (1) | KR900000683B1 (no) |
AU (1) | AU571635B2 (no) |
CA (1) | CA1243035A (no) |
DE (1) | DE3560717D1 (no) |
DK (1) | DK21085A (no) |
ES (1) | ES8609230A1 (no) |
FI (1) | FI79698C (no) |
GR (1) | GR850106B (no) |
HU (1) | HU195638B (no) |
IL (1) | IL74068A (no) |
NO (1) | NO160576C (no) |
NZ (1) | NZ210839A (no) |
PT (1) | PT79835B (no) |
ZW (1) | ZW1085A1 (no) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA1276937C (en) * | 1985-04-19 | 1990-11-27 | Smith Kline & French Canada Ltd. | Leukotriene antagonists |
US4871771A (en) * | 1988-02-04 | 1989-10-03 | Smithkline Beckman Corporation | Leukotriene antagonists |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL277345A (no) * | 1961-04-17 | 1900-01-01 | ||
FR2468362A1 (fr) * | 1978-07-12 | 1981-05-08 | Oreal | Compositions cosmetiques a base de dithioethers pour le traitement de l'etat gras des cheveux et de la peau, nouveaux composes et leur procede d'obtention |
US4269731A (en) * | 1979-08-27 | 1981-05-26 | Argus Chemical Corporation | Antimony mercaptocarboxylic acid ester stabilizers for polyvinyl chloride resin compositions and process |
-
1985
- 1985-01-14 CA CA000472021A patent/CA1243035A/en not_active Expired
- 1985-01-14 NO NO850154A patent/NO160576C/no unknown
- 1985-01-15 GR GR850106A patent/GR850106B/el unknown
- 1985-01-15 NZ NZ210839A patent/NZ210839A/en unknown
- 1985-01-15 ES ES539566A patent/ES8609230A1/es not_active Expired
- 1985-01-16 EP EP85300276A patent/EP0168902B1/en not_active Expired
- 1985-01-16 ZW ZW10/85A patent/ZW1085A1/xx unknown
- 1985-01-16 IL IL74068A patent/IL74068A/xx unknown
- 1985-01-16 DE DE8585300276T patent/DE3560717D1/de not_active Expired
- 1985-01-17 PT PT79835A patent/PT79835B/pt unknown
- 1985-01-17 FI FI850226A patent/FI79698C/fi not_active IP Right Cessation
- 1985-01-17 HU HU85199A patent/HU195638B/hu not_active IP Right Cessation
- 1985-01-17 DK DK21085A patent/DK21085A/da unknown
- 1985-01-18 AU AU37779/85A patent/AU571635B2/en not_active Ceased
- 1985-01-19 KR KR1019850000304A patent/KR900000683B1/ko not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
DK21085D0 (da) | 1985-01-17 |
NO160576C (no) | 1989-05-03 |
PT79835A (en) | 1985-02-01 |
CA1243035A (en) | 1988-10-11 |
HUT37748A (en) | 1986-02-28 |
FI850226L (fi) | 1985-07-20 |
DE3560717D1 (en) | 1987-11-05 |
DK21085A (da) | 1985-07-20 |
NO850154L (no) | 1985-07-22 |
HU195638B (en) | 1988-06-28 |
PT79835B (en) | 1986-10-28 |
ES8609230A1 (es) | 1986-07-16 |
GR850106B (no) | 1985-05-16 |
KR850005407A (ko) | 1985-08-26 |
FI79698C (fi) | 1990-02-12 |
AU3777985A (en) | 1985-08-01 |
EP0168902A1 (en) | 1986-01-22 |
EP0168902B1 (en) | 1987-09-30 |
FI850226A0 (fi) | 1985-01-17 |
KR900000683B1 (ko) | 1990-02-03 |
FI79698B (fi) | 1989-10-31 |
IL74068A (en) | 1988-08-31 |
ZW1085A1 (en) | 1985-04-24 |
NZ210839A (en) | 1987-10-30 |
AU571635B2 (en) | 1988-04-21 |
ES539566A0 (es) | 1986-07-16 |
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