NO891114L - Analogifremgangsmaate for fremstilling av terapeutisk aktive arakidonsyre-derivater. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive arakidonsyre-derivater.

Info

Publication number
NO891114L
NO891114L NO89891114A NO891114A NO891114L NO 891114 L NO891114 L NO 891114L NO 89891114 A NO89891114 A NO 89891114A NO 891114 A NO891114 A NO 891114A NO 891114 L NO891114 L NO 891114L
Authority
NO
Norway
Prior art keywords
preparation
acid derivatives
therapeutic active
analogy procedure
arakidonic
Prior art date
Application number
NO89891114A
Other languages
English (en)
Other versions
NO891114D0 (no
NO169648B (no
NO169648C (no
Inventor
Edward S Lazer
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of NO891114D0 publication Critical patent/NO891114D0/no
Publication of NO891114L publication Critical patent/NO891114L/no
Publication of NO169648B publication Critical patent/NO169648B/no
Publication of NO169648C publication Critical patent/NO169648C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/205Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing only six-membered aromatic rings as cyclic parts with unsaturation outside the rings
    • C07C39/21Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic, containing only six-membered aromatic rings as cyclic parts with unsaturation outside the rings with at least one hydroxy group on a non-condensed ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/24Halogenated derivatives
    • C07C39/373Halogenated derivatives with all hydroxy groups on non-condensed rings and with unsaturation outside the aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00Ethers; Compounds having groups, groups or groups
    • C07C43/02Ethers
    • C07C43/20Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/56Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds
    • C07C45/562Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with nitrogen as the only hetero atom
    • C07C45/565Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds from heterocyclic compounds with nitrogen as the only hetero atom by reaction with hexamethylene-tetramine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
NO891114A 1988-03-21 1989-03-15 Analogifremgangsmaate for fremstilling av terapeutisk aktive arakidonsyre-derivater NO169648C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US17051288A 1988-03-21 1988-03-21

Publications (4)

Publication Number Publication Date
NO891114D0 NO891114D0 (no) 1989-03-15
NO891114L true NO891114L (no) 1989-09-22
NO169648B NO169648B (no) 1992-04-13
NO169648C NO169648C (no) 1992-07-22

Family

ID=22620151

Family Applications (1)

Application Number Title Priority Date Filing Date
NO891114A NO169648C (no) 1988-03-21 1989-03-15 Analogifremgangsmaate for fremstilling av terapeutisk aktive arakidonsyre-derivater

Country Status (16)

Country Link
EP (1) EP0334119B1 (no)
JP (1) JPH024729A (no)
KR (1) KR890014514A (no)
AU (1) AU628324B2 (no)
DD (1) DD283602A5 (no)
DE (1) DE68907095T2 (no)
DK (1) DK134489A (no)
ES (1) ES2056983T3 (no)
FI (1) FI891295A (no)
HU (2) HU207858B (no)
IL (1) IL89666A0 (no)
NO (1) NO169648C (no)
NZ (1) NZ228410A (no)
PH (1) PH26928A (no)
PT (1) PT90066B (no)
ZA (1) ZA892086B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993016067A1 (en) * 1992-02-11 1993-08-19 Allergan, Inc. Heteroaryl substituted phenylethenyl compounds having retinoid-like biological activity
ES2089736T3 (es) * 1992-10-28 1996-10-01 Shionogi & Co Derivados de bencilideno.
ES2087019B1 (es) * 1994-02-08 1997-03-16 Bobel246 S L Uso de derivados de fenoles 2,4-disubstituidos como inhibidores de la 5-lipoxigenasa.
TW544448B (en) * 1997-07-11 2003-08-01 Novartis Ag Pyridine derivatives
US6376524B1 (en) * 2000-06-21 2002-04-23 Sunesis Pharmaceuticals, Inc. Triphenyl compounds as interleukin-4 antagonists
EP1368306B1 (en) 2001-01-18 2013-01-16 Welichem Biotech Inc. Novel 1,2-diphenylethene derivatives for treatment of immune diseases
JP4425628B2 (ja) 2001-07-23 2010-03-03 ジョンソン・アンド・ジョンソン・コンシューマー・カンパニーズ・インコーポレイテッド 細胞保護化合物、薬学的処方物および美容用処方物、ならびに方法
CA2551567C (en) * 2003-12-23 2014-04-29 Abraxis Bioscience, Inc. Propofol analogs, process for their preparation, and methods of use
WO2006078941A2 (en) * 2005-01-20 2006-07-27 Sirtris Pharmaceuticals, Inc. Novel sirtuin activating compounds and methods of use thereof
BR112020009158A2 (pt) 2017-11-10 2020-10-27 Dermavant Sciences GmbH processo para o preparo de um composto, composto e composição farmacêutica

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3188315A (en) * 1960-05-18 1965-06-08 Schering Corp Novel compounds for lowering blood cholesterol levels
FR1390978A (fr) * 1963-11-20 1965-03-05 Ind Chimique Sa Procédé de préparation de l'alpha-(thiényl-2) 4-hydroxystilbène et de quelques dérivés et produits obtenus
US4758586A (en) * 1985-02-01 1988-07-19 Usv Pharmaceutical Corp. Indolyl compounds and hyposensitivity use thereof
DE3602473A1 (de) * 1986-01-28 1987-07-30 Basf Ag Vinylphenolderivate, ihre herstellung und verwendung
US4743606A (en) * 1986-03-25 1988-05-10 Boehringer Ingelheim Pharmaceuticals, Inc. 3-[2-(3',5'-di-t-butyl-4'-hydroxyphenyl)ethenyl]pyridine having anti-inflammatory and anti-arthritic properties
US4851423A (en) * 1986-12-10 1989-07-25 Schering Corporation Pharmaceutically active compounds
CA1338645C (en) * 1987-01-06 1996-10-15 George R. Pettit Isolation, structural elucidation and synthesis of novel antineoplastic substances denominated "combretastatins"

Also Published As

Publication number Publication date
EP0334119A1 (en) 1989-09-27
PH26928A (en) 1992-12-03
DE68907095D1 (de) 1993-07-22
EP0334119B1 (en) 1993-06-16
NO891114D0 (no) 1989-03-15
HU207858B (en) 1993-06-28
NZ228410A (en) 1993-08-26
ES2056983T3 (es) 1994-10-16
PT90066B (pt) 1994-05-31
DK134489D0 (da) 1989-03-20
DD283602A5 (de) 1990-10-17
IL89666A0 (en) 1989-09-28
DE68907095T2 (de) 1994-01-05
FI891295A0 (fi) 1989-03-20
DK134489A (da) 1989-09-22
PT90066A (pt) 1989-11-10
FI891295A (fi) 1989-09-22
JPH024729A (ja) 1990-01-09
AU628324B2 (en) 1992-09-17
NO169648B (no) 1992-04-13
AU3151489A (en) 1989-09-21
NO169648C (no) 1992-07-22
ZA892086B (en) 1990-11-28
HU9201174D0 (en) 1992-07-28
KR890014514A (ko) 1989-10-24
HUT50093A (en) 1989-12-28

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