NO148375C - ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVITY 3-CHLORO-7-ALFA-AMINO-ACYLCEPHALOSPORINE - Google Patents

ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVITY 3-CHLORO-7-ALFA-AMINO-ACYLCEPHALOSPORINE

Info

Publication number: NO148375C
Authority: NO; Norway
Prior art keywords: acylcephalosporine; alfa; chloro; amino; preparation
Prior art date: 1973-02-23

Application number

NO740606A

Other languages

Norwegian (no)

Other versions

NO148375B (en

NO740606L (en

Inventor

Robert Raymond Chauvette

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1973-02-23

Filing date

1974-02-22

Publication date

1983-09-28

1974-02-22 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1974-08-26 Publication of NO740606L publication Critical patent/NO740606L/en

1983-06-20 Publication of NO148375B publication Critical patent/NO148375B/en

1983-09-28 Publication of NO148375C publication Critical patent/NO148375C/en

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/02—Preparation
- C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/59—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with hetero atoms directly attached in position 3
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

NO740606A 1973-02-23 1974-02-22 ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVITY 3-CHLORO-7-ALFA-AMINO-ACYLCEPHALOSPORINE NO148375C (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US33538173A	1973-02-23	1973-02-23

Publications (3)

Publication Number	Publication Date
NO740606L NO740606L (en)	1974-08-26
NO148375B NO148375B (en)	1983-06-20
NO148375C true NO148375C (en)	1983-09-28

Family

ID=23311540

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
NO740606A NO148375C (en)	1973-02-23	1974-02-22	ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVITY 3-CHLORO-7-ALFA-AMINO-ACYLCEPHALOSPORINE
NO792681A NO148377C (en)	1973-02-23	1979-08-16	3-CHLORO-7-ALFA-AMINO-ACYLCEPHALOSPORINE COMPOUNDS FOR USE AS INTERMEDIATES IN THE PREPARATION OF THERAPEUTICALLY EFFECTIVE CEPHALOSPORINE DERIVATIVES

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
NO792681A NO148377C (en)	1973-02-23	1979-08-16	3-CHLORO-7-ALFA-AMINO-ACYLCEPHALOSPORINE COMPOUNDS FOR USE AS INTERMEDIATES IN THE PREPARATION OF THERAPEUTICALLY EFFECTIVE CEPHALOSPORINE DERIVATIVES

Country Status (37)

Country	Link
JP (4)	JPS6139313B2 (en)
AR (1)	AR199510A1 (en)
AT (1)	AT333953B (en)
BE (1)	BE811495A (en)
BR (1)	BR7401384D0 (en)
CA (1)	CA1016537A (en)
CH (1)	CH593988A5 (en)
CS (1)	CS187409B2 (en)
CY (1)	CY1043A (en)
DD (1)	DD110278A5 (en)
DE (1)	DE2408698C2 (en)
DK (1)	DK153157C (en)
EG (1)	EG11104A (en)
ES (1)	ES423531A1 (en)
FI (1)	FI63035C (en)
FR (1)	FR2218877B1 (en)
GB (1)	GB1461323A (en)
GT (1)	GT197432133A (en)
HK (1)	HK20080A (en)
HU (1)	HU166849B (en)
IE (1)	IE39046B1 (en)
IL (1)	IL44262A (en)
IN (1)	IN139620B (en)
KE (1)	KE3027A (en)
MW (1)	MW674A1 (en)
MY (1)	MY8100024A (en)
NL (1)	NL179057C (en)
NO (2)	NO148375C (en)
OA (1)	OA04809A (en)
PH (1)	PH9616A (en)
PL (1)	PL88702B1 (en)
RO (1)	RO64663A (en)
SE (1)	SE411212B (en)
SU (1)	SU676166A3 (en)
YU (1)	YU36970B (en)
ZA (1)	ZA741191B (en)
ZM (1)	ZM3574A1 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AT342197B (en) *	1975-02-20	1978-03-28	Ciba Geigy Ag	NEW PROCESS FOR PRODUCING 3-CEPHEM CONNECTIONS
CH619233A5 (en) *	1975-07-31	1980-09-15	Ciba Geigy Ag
CH622802A5 (en) *	1975-08-20	1981-04-30	Ciba Geigy Ag
IE45158B1 (en) *	1976-08-16	1982-06-30	Lilly Co Eli	3-chloro-cephem synthesis
DE3508258A1 (en) *	1985-03-08	1986-09-18	Bayer Ag, 5090 Leverkusen	SS LACTAMANTIBIOTICS, METHOD FOR THE PRODUCTION AND THEIR USE AS AND IN MEDICINAL PRODUCTS
DE3509618A1 (en) *	1985-03-16	1986-09-18	Bayer Ag, 5090 Leverkusen	SS LACTAM ANTIBIOTICS, METHOD FOR THE PRODUCTION AND THEIR USE AS A MEDICINAL PRODUCT
JPS6436445U (en) *	1987-08-28	1989-03-06
DE3803169A1 (en)	1988-02-03	1989-08-17	Bayer Ag	SS LACTAM ANTIBIOTICS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS AND IN MEDICINAL PRODUCTS
ES2010075A6 (en) *	1989-01-10	1989-10-16	Antibioticos Sa	Process for the preparation of 3-chloro-cefem compounds.
JP2539459Y2 (en) *	1991-12-18	1997-06-25	三重ホーロー株式会社	Assembled garbage incinerator
IT1255458B (en) *	1992-05-11	1995-11-02	Col Marco Da	PROCEDURE FOR THE PREPARATION OF HALOGENATED BETA-LACTAMIC DERIVATIVES
ES2079327B1 (en)	1994-12-13	1996-08-01	Lilly Sa	PHARMACEUTICAL FORMULATIONS OF CEFACLOR.
CN101805357B (en) *	2010-04-28	2012-01-11	陶灵刚	Cefaclor compound and novel preparation method thereof
CN103588790A (en) *	2013-11-29	2014-02-19	中国科学院长春应用化学研究所	Preparation method of 7-amino-3-chloro-3-cephem-4-carboxylic acid-p-nitrobenzyl ester
CN106632400A (en) *	2016-12-16	2017-05-10	石家庄柏奇化工有限公司	Method for preparing 7-ACCA by removing 4-nitrobenzyl through catalytic hydrogenation of Pd-C

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3641021A (en) *	1969-04-18	1972-02-08	Lilly Co Eli	3 7-(ring-substituted) cephalosporin compounds
DE2265798C2 (en) *	1971-06-24	1985-09-26	Fujisawa Pharmaceutical Co., Ltd., Osaka	Process for the preparation of oxoazetidine derivatives
AR206201A1 (en) *	1972-06-29	1976-07-07	Ciba Geigy Ag	PROCEDURE FOR OBTAINING ACID COMPOUNDS 7BETA-AMINO-3-CEFEM-3-01-4-CARBOXILICO0-SUBSTITUIDOS

1974
- 1974-02-18 YU YU0399/74A patent/YU36970B/en unknown
- 1974-02-21 AT AT142574A patent/AT333953B/en not_active IP Right Cessation
- 1974-02-22 NO NO740606A patent/NO148375C/en unknown
- 1974-02-22 NL NLAANVRAGE7402489,A patent/NL179057C/en not_active IP Right Cessation
- 1974-02-22 SU SU742000614A patent/SU676166A3/en active
- 1974-02-22 DK DK095274A patent/DK153157C/en not_active IP Right Cessation
- 1974-02-22 ZM ZM35/74A patent/ZM3574A1/en unknown
- 1974-02-22 GT GT197432133A patent/GT197432133A/en unknown
- 1974-02-22 ES ES423531A patent/ES423531A1/en not_active Expired
- 1974-02-22 GB GB809774A patent/GB1461323A/en not_active Expired
- 1974-02-22 IL IL44262A patent/IL44262A/en unknown
- 1974-02-22 BE BE1005741A patent/BE811495A/en not_active IP Right Cessation
- 1974-02-22 IN IN381/CAL/74A patent/IN139620B/en unknown
- 1974-02-22 CA CA193,236A patent/CA1016537A/en not_active Expired
- 1974-02-22 ZA ZA00741191A patent/ZA741191B/en unknown
- 1974-02-22 AR AR252493A patent/AR199510A1/en active
- 1974-02-22 PH PH15540*UA patent/PH9616A/en unknown
- 1974-02-22 FI FI525/74A patent/FI63035C/en active
- 1974-02-22 DD DD176751A patent/DD110278A5/xx unknown
- 1974-02-22 BR BR1384/74A patent/BR7401384D0/en unknown
- 1974-02-22 SE SE7402413A patent/SE411212B/en not_active IP Right Cessation
- 1974-02-22 MW MW6/74*UA patent/MW674A1/en unknown
- 1974-02-22 DE DE2408698A patent/DE2408698C2/en not_active Expired
- 1974-02-22 HU HUEI528A patent/HU166849B/hu unknown
- 1974-02-22 CY CY1043A patent/CY1043A/en unknown
- 1974-02-22 FR FR7406153A patent/FR2218877B1/fr not_active Expired
- 1974-02-22 IE IE00356/74A patent/IE39046B1/en unknown
- 1974-02-23 RO RO7477796A patent/RO64663A/en unknown
- 1974-02-23 EG EG52/74A patent/EG11104A/en active
- 1974-02-23 PL PL1974169035A patent/PL88702B1/pl unknown
- 1974-02-23 JP JP49021870A patent/JPS6139313B2/ja not_active Expired
- 1974-02-23 OA OA55128A patent/OA04809A/en unknown
- 1974-02-25 CH CH265374A patent/CH593988A5/xx not_active IP Right Cessation
- 1974-02-25 CS CS741376A patent/CS187409B2/en unknown
1979
- 1979-08-16 NO NO792681A patent/NO148377C/en unknown
1980
- 1980-02-27 KE KE3027A patent/KE3027A/en unknown
- 1980-04-17 HK HK200/80A patent/HK20080A/en unknown
1981
- 1981-02-20 JP JP2532981A patent/JPS56138191A/en active Granted
- 1981-02-20 JP JP2532881A patent/JPS56138190A/en active Granted
- 1981-02-20 JP JP2533081A patent/JPS56138192A/en active Granted
- 1981-12-30 MY MY24/81A patent/MY8100024A/en unknown

Also Published As

Publication number	Publication date
HU166849B (en)	1975-06-28
NL7402489A (en)	1974-08-27
AU6591674A (en)	1975-08-28
SE411212B (en)	1979-12-10
MY8100024A (en)	1981-12-31
CH593988A5 (en)	1977-12-30
AR199510A1 (en)	1974-09-09
IL44262A (en)	1977-08-31
CY1043A (en)	1980-08-01
GT197432133A (en)	1975-08-16
JPS56138191A (en)	1981-10-28
SU676166A3 (en)	1979-07-25
IN139620B (en)	1976-07-10
MW674A1 (en)	1975-04-09
ES423531A1 (en)	1976-05-16
IE39046L (en)	1974-08-23
IL44262A0 (en)	1974-05-16
BE811495A (en)	1974-08-22
JPS49110689A (en)	1974-10-22
NO148375B (en)	1983-06-20
NL179057B (en)	1986-02-03
OA04809A (en)	1980-08-31
JPS6139313B2 (en)	1986-09-03
IE39046B1 (en)	1978-07-19
PH9616A (en)	1976-01-20
DE2408698A1 (en)	1974-09-05
YU36970B (en)	1984-08-31
KE3027A (en)	1980-03-14
FR2218877A1 (en)	1974-09-20
AT333953B (en)	1976-12-27
ATA142574A (en)	1976-04-15
NO740606L (en)	1974-08-26
RO64663A (en)	1979-02-15
PL88702B1 (en)	1976-09-30
YU39974A (en)	1982-06-18
NO148377B (en)	1983-06-20
ZM3574A1 (en)	1975-11-21
ZA741191B (en)	1975-10-29
JPS6140235B2 (en)	1986-09-08
DK153157B (en)	1988-06-20
JPS56138192A (en)	1981-10-28
DK153157C (en)	1988-10-31
FI63035B (en)	1982-12-31
HK20080A (en)	1980-04-25
NO792681L (en)	1974-08-26
FR2218877B1 (en)	1977-03-11
CS187409B2 (en)	1979-01-31
GB1461323A (en)	1977-01-13
BR7401384D0 (en)	1974-11-05
JPS56138190A (en)	1981-10-28
FI63035C (en)	1983-04-11
DE2408698C2 (en)	1983-11-10
DD110278A5 (en)	1974-12-12
NL179057C (en)	1986-07-01
EG11104A (en)	1976-12-31
JPS6140236B2 (en)	1986-09-08
NO148377C (en)	1983-09-28
JPS6140237B2 (en)	1986-09-08
CA1016537A (en)	1977-08-30

Publication	Publication Date	Title
NO145382C (en)	1982-03-10	ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 3-AMINO-INDAZOLCARBOXYLIC ACID DERIVATIVES.
NO145273C (en)	1982-02-17	N-FORMYL-ALFA-L-ASPARTYL-L-PHENYLALANINE FOR USING THE PREPARATION OF ALFA-L-ASPARTYL-L-PHENYLALANINAL COOLESTERS
NO143218C (en)	1981-01-02	ANALOGY PROCEDURE FOR THE PREPARATION OF NONAPEPTIDAMIDES WITH LH-RH ACTIVITY
NO143219C (en)	1981-01-07	ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE RELATIONS.
NO140854C (en)	1979-11-28	ANALOGICAL PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE NONAPEPTIDE AMIDES
NO145056C (en)	1982-01-04	(S) -1-ARYLOXY-2-PROPANOLE DERIVATIVES FOR THE PREPARATION OF THERAPEUTIC ACTIVE (S) -1-ARYLOXY-3-AMINO-2-PROPANOLE DERIVATIVES
NO149281C (en)	1984-03-21	ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE 7ALFA METHOXYPHALOSPORINE DERIVATIVES
NO141717C (en)	1980-04-30	ANALOGUE PROCEDURE FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE TRIAZOLOPYRIDAZINES
NO142174C (en)	1980-07-09	METHOD OF ANALOGUE FOR THE PREPARATION OF THERAPEUTIC ACTIVITY 1,1-DIARYL-1-OXADADZAZOL ALKYLAMINES
NO148375C (en)	1983-09-28	ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVITY 3-CHLORO-7-ALFA-AMINO-ACYLCEPHALOSPORINE
NO140597C (en)	1979-10-03	ANALOGICAL PROCEDURES FOR THE PREPARATION OF THERAPEUTIC ACTIVE 8-AZAPURIN-6-ON DERIVATIVES
NO144926C (en)	1981-12-09	ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE 1-BENZAZOLYLALKYL-4-SUBSTITUTED PIPERIDINES
NO142303C (en)	1980-07-30	ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY EFFECTIVE OKSAZOL DERIVATIVES
NO141850C (en)	1980-06-04	ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE PYRAZOLD DERIVATIVES.
NO137387C (en)	1978-02-22	ANALOGICAL PROCEDURE FOR THE PREPARATION OF 5-METHYLTIOPYRIMIDINES WITH THERAPEUTIC EFFECT
NO141755C (en)	1980-05-14	ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY EFFECTIVE DOTRIACONTAPEPTIDAMIDES
NO146596C (en)	1982-11-03	PROCEDURE FOR THE PREPARATION OF 6-DEOXYTE TRACYCLINES
NO143064C (en)	1980-12-10	ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE HYDROXYLYCYLXANTINES
SE417601B (en)	1981-03-30	PROCEDURE FOR THE PREPARATION OF AMIDINOCARBAMIDS
NO843825L (en)	1974-08-02	PROCEDURE FOR THE PREPARATION OF 6-DEOXYTHETRACYCLINE
NO141208C (en)	1980-01-30	ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVITY 2- (PHENOXYLKYLTIO) IMIDAZOLE COMPOUNDS
SE409716B (en)	1979-09-03	ANALOGICAL PROCEDURE FOR THE PREPARATION OF 11BETA-ALKYL-DELTAŸ4-ESTRENES
NO145383C (en)	1982-03-10	ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVE SUBSTITUTED INDOLS.
NO143499C (en)	1981-02-25	ANALOGUE PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE INHANDER DERIVATIVES
NO148376C (en)	1983-09-28	ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTIC ACTIVITY 7-ACYLAMINO-3-HALOGEN-CEPHALOSPORINE COMPOUNDS