FR2218877A1 - - Google Patents

Info

Publication number
FR2218877A1
FR2218877A1 FR7406153A FR7406153A FR2218877A1 FR 2218877 A1 FR2218877 A1 FR 2218877A1 FR 7406153 A FR7406153 A FR 7406153A FR 7406153 A FR7406153 A FR 7406153A FR 2218877 A1 FR2218877 A1 FR 2218877A1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7406153A
Other languages
French (fr)
Other versions
FR2218877B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of FR2218877A1 publication Critical patent/FR2218877A1/fr
Application granted granted Critical
Publication of FR2218877B1 publication Critical patent/FR2218877B1/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02Preparation
    • C07D501/04Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/59Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3 with hetero atoms directly attached in position 3
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FR7406153A 1973-02-23 1974-02-22 Expired FR2218877B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US33538173A 1973-02-23 1973-02-23

Publications (2)

Publication Number Publication Date
FR2218877A1 true FR2218877A1 (en) 1974-09-20
FR2218877B1 FR2218877B1 (en) 1977-03-11

Family

ID=23311540

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7406153A Expired FR2218877B1 (en) 1973-02-23 1974-02-22

Country Status (37)

Country Link
JP (4) JPS6139313B2 (en)
AR (1) AR199510A1 (en)
AT (1) AT333953B (en)
BE (1) BE811495A (en)
BR (1) BR7401384D0 (en)
CA (1) CA1016537A (en)
CH (1) CH593988A5 (en)
CS (1) CS187409B2 (en)
CY (1) CY1043A (en)
DD (1) DD110278A5 (en)
DE (1) DE2408698C2 (en)
DK (1) DK153157C (en)
EG (1) EG11104A (en)
ES (1) ES423531A1 (en)
FI (1) FI63035C (en)
FR (1) FR2218877B1 (en)
GB (1) GB1461323A (en)
GT (1) GT197432133A (en)
HK (1) HK20080A (en)
HU (1) HU166849B (en)
IE (1) IE39046B1 (en)
IL (1) IL44262A (en)
IN (1) IN139620B (en)
KE (1) KE3027A (en)
MW (1) MW674A1 (en)
MY (1) MY8100024A (en)
NL (1) NL179057C (en)
NO (2) NO148375C (en)
OA (1) OA04809A (en)
PH (1) PH9616A (en)
PL (1) PL88702B1 (en)
RO (1) RO64663A (en)
SE (1) SE411212B (en)
SU (1) SU676166A3 (en)
YU (1) YU36970B (en)
ZA (1) ZA741191B (en)
ZM (1) ZM3574A1 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0377958A2 (en) * 1989-01-10 1990-07-18 Antibioticos, S.A. Process for the preparation of 3-chloro-cefem compounds
EP0570058A2 (en) * 1992-05-11 1993-11-18 Biochimica Opos Spa Process for the preparation of halogenated beta-lactam compounds

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT342197B (en) * 1975-02-20 1978-03-28 Ciba Geigy Ag NEW PROCESS FOR PRODUCING 3-CEPHEM CONNECTIONS
CH619233A5 (en) * 1975-07-31 1980-09-15 Ciba Geigy Ag
CH622802A5 (en) * 1975-08-20 1981-04-30 Ciba Geigy Ag
IE45158B1 (en) * 1976-08-16 1982-06-30 Lilly Co Eli 3-chloro-cephem synthesis
DE3508258A1 (en) * 1985-03-08 1986-09-18 Bayer Ag, 5090 Leverkusen SS LACTAMANTIBIOTICS, METHOD FOR THE PRODUCTION AND THEIR USE AS AND IN MEDICINAL PRODUCTS
DE3509618A1 (en) * 1985-03-16 1986-09-18 Bayer Ag, 5090 Leverkusen SS LACTAM ANTIBIOTICS, METHOD FOR THE PRODUCTION AND THEIR USE AS A MEDICINAL PRODUCT
JPS6436445U (en) * 1987-08-28 1989-03-06
DE3803169A1 (en) 1988-02-03 1989-08-17 Bayer Ag SS LACTAM ANTIBIOTICS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS AND IN MEDICINAL PRODUCTS
JP2539459Y2 (en) * 1991-12-18 1997-06-25 三重ホーロー株式会社 Assembled garbage incinerator
ES2079327B1 (en) 1994-12-13 1996-08-01 Lilly Sa PHARMACEUTICAL FORMULATIONS OF CEFACLOR.
CN101805357B (en) * 2010-04-28 2012-01-11 陶灵刚 Cefaclor compound and novel preparation method thereof
CN103588790A (en) * 2013-11-29 2014-02-19 中国科学院长春应用化学研究所 Preparation method of 7-amino-3-chloro-3-cephem-4-carboxylic acid-p-nitrobenzyl ester
CN106632400A (en) * 2016-12-16 2017-05-10 石家庄柏奇化工有限公司 Method for preparing 7-ACCA by removing 4-nitrobenzyl through catalytic hydrogenation of Pd-C

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2143211A1 (en) * 1971-06-24 1973-02-02 Fujisawa Pharmaceutical Co

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds
AR206201A1 (en) * 1972-06-29 1976-07-07 Ciba Geigy Ag PROCEDURE FOR OBTAINING ACID COMPOUNDS 7BETA-AMINO-3-CEFEM-3-01-4-CARBOXILICO0-SUBSTITUIDOS

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2143211A1 (en) * 1971-06-24 1973-02-02 Fujisawa Pharmaceutical Co

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0377958A2 (en) * 1989-01-10 1990-07-18 Antibioticos, S.A. Process for the preparation of 3-chloro-cefem compounds
EP0377958A3 (en) * 1989-01-10 1992-01-08 Antibioticos, S.A. Process for the preparation of 3-chloro-cefem compounds
EP0570058A2 (en) * 1992-05-11 1993-11-18 Biochimica Opos Spa Process for the preparation of halogenated beta-lactam compounds
EP0570058A3 (en) * 1992-05-11 1994-03-23 Opos Biochimica Srl
US5532353A (en) * 1992-05-11 1996-07-02 Biochimica Opos Spa Process for the preparation of halogenated β-lactam compounds

Also Published As

Publication number Publication date
HU166849B (en) 1975-06-28
NL7402489A (en) 1974-08-27
AU6591674A (en) 1975-08-28
SE411212B (en) 1979-12-10
MY8100024A (en) 1981-12-31
CH593988A5 (en) 1977-12-30
AR199510A1 (en) 1974-09-09
IL44262A (en) 1977-08-31
CY1043A (en) 1980-08-01
GT197432133A (en) 1975-08-16
JPS56138191A (en) 1981-10-28
SU676166A3 (en) 1979-07-25
IN139620B (en) 1976-07-10
MW674A1 (en) 1975-04-09
ES423531A1 (en) 1976-05-16
IE39046L (en) 1974-08-23
IL44262A0 (en) 1974-05-16
BE811495A (en) 1974-08-22
JPS49110689A (en) 1974-10-22
NO148375B (en) 1983-06-20
NL179057B (en) 1986-02-03
OA04809A (en) 1980-08-31
JPS6139313B2 (en) 1986-09-03
IE39046B1 (en) 1978-07-19
PH9616A (en) 1976-01-20
DE2408698A1 (en) 1974-09-05
YU36970B (en) 1984-08-31
KE3027A (en) 1980-03-14
AT333953B (en) 1976-12-27
ATA142574A (en) 1976-04-15
NO740606L (en) 1974-08-26
RO64663A (en) 1979-02-15
PL88702B1 (en) 1976-09-30
YU39974A (en) 1982-06-18
NO148377B (en) 1983-06-20
NO148375C (en) 1983-09-28
ZM3574A1 (en) 1975-11-21
ZA741191B (en) 1975-10-29
JPS6140235B2 (en) 1986-09-08
DK153157B (en) 1988-06-20
JPS56138192A (en) 1981-10-28
DK153157C (en) 1988-10-31
FI63035B (en) 1982-12-31
HK20080A (en) 1980-04-25
NO792681L (en) 1974-08-26
FR2218877B1 (en) 1977-03-11
CS187409B2 (en) 1979-01-31
GB1461323A (en) 1977-01-13
BR7401384D0 (en) 1974-11-05
JPS56138190A (en) 1981-10-28
FI63035C (en) 1983-04-11
DE2408698C2 (en) 1983-11-10
DD110278A5 (en) 1974-12-12
NL179057C (en) 1986-07-01
EG11104A (en) 1976-12-31
JPS6140236B2 (en) 1986-09-08
NO148377C (en) 1983-09-28
JPS6140237B2 (en) 1986-09-08
CA1016537A (en) 1977-08-30

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Legal Events

Date Code Title Description
CC Supplementary protection certificate (spc) laid open to the public (law of 25 june 1990)

Free format text: 92C0052, 920323

CC Supplementary protection certificate (spc) laid open to the public (law of 25 june 1990)

Free format text: 92C0074, 920415

CB Supplementary protection certificate (spc) granted (law of 25 june 1990)

Free format text: 92C0074, 740722

CL Concession to grant licences