NL1005338C2 - Werkwijze voor de bereiding van een optisch actief fenylglycidylzuurderivaat. - Google Patents

Werkwijze voor de bereiding van een optisch actief fenylglycidylzuurderivaat. Download PDF

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Publication number
NL1005338C2
NL1005338C2 NL1005338A NL1005338A NL1005338C2 NL 1005338 C2 NL1005338 C2 NL 1005338C2 NL 1005338 A NL1005338 A NL 1005338A NL 1005338 A NL1005338 A NL 1005338A NL 1005338 C2 NL1005338 C2 NL 1005338C2
Authority
NL
Netherlands
Prior art keywords
formula
compound
optically active
derived
hetero
Prior art date
Application number
NL1005338A
Other languages
English (en)
Dutch (nl)
Inventor
Gerardus Karel Maria Verzijl
Bernardus Kaptein
Original Assignee
Dsm Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm Nv filed Critical Dsm Nv
Priority to NL1005338A priority Critical patent/NL1005338C2/nl
Priority to CA002228196A priority patent/CA2228196A1/en
Priority to DE69800900T priority patent/DE69800900D1/de
Priority to AT98200484T priority patent/ATE202094T1/de
Priority to EP98200484A priority patent/EP0860439B1/en
Priority to IL12339198A priority patent/IL123391A0/xx
Priority to JP10076391A priority patent/JPH10279572A/ja
Priority to CN98107076A priority patent/CN1197070A/zh
Priority to HU9800372A priority patent/HUP9800372A3/hu
Priority to US09/027,619 priority patent/US6025506A/en
Application granted granted Critical
Publication of NL1005338C2 publication Critical patent/NL1005338C2/nl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C219/00—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C219/24—Compounds containing amino and esterified hydroxy groups bound to the same carbon skeleton having esterified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04—One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08—One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
NL1005338A 1997-02-21 1997-02-21 Werkwijze voor de bereiding van een optisch actief fenylglycidylzuurderivaat. NL1005338C2 (nl)

Priority Applications (10)

Application Number Priority Date Filing Date Title
NL1005338A NL1005338C2 (nl) 1997-02-21 1997-02-21 Werkwijze voor de bereiding van een optisch actief fenylglycidylzuurderivaat.
CA002228196A CA2228196A1 (en) 1997-02-21 1998-01-29 Process for preparing an optically active phenylglycidyl acid derivative
AT98200484T ATE202094T1 (de) 1997-02-21 1998-02-16 Verfahren zur herstellung eines optisch aktiven phenylglycidylsäurederivates
EP98200484A EP0860439B1 (en) 1997-02-21 1998-02-16 Process for preparing an optically active phenylglycidyl acid derivative
DE69800900T DE69800900D1 (de) 1997-02-21 1998-02-16 Verfahren zur Herstellung eines optisch aktiven Phenylglycidylsäurederivates
IL12339198A IL123391A0 (en) 1997-02-21 1998-02-19 Process for preparing an optically active phenylglycidyl acid derivative
JP10076391A JPH10279572A (ja) 1997-02-21 1998-02-19 光学活性なフェニルグリシジル酸誘導体の製造法
CN98107076A CN1197070A (zh) 1997-02-21 1998-02-20 旋光苯基缩水甘油酸衍生物的制备方法
HU9800372A HUP9800372A3 (en) 1997-02-21 1998-02-20 Process for producing trans-phenyl-glycidyl-acid derivatives
US09/027,619 US6025506A (en) 1997-02-21 1998-02-23 Process for preparing an optically active phenylglycidyl acid derivative

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL1005338A NL1005338C2 (nl) 1997-02-21 1997-02-21 Werkwijze voor de bereiding van een optisch actief fenylglycidylzuurderivaat.
NL1005338 1997-02-21

Publications (1)

Publication Number Publication Date
NL1005338C2 true NL1005338C2 (nl) 1998-08-24

Family

ID=19764467

Family Applications (1)

Application Number Title Priority Date Filing Date
NL1005338A NL1005338C2 (nl) 1997-02-21 1997-02-21 Werkwijze voor de bereiding van een optisch actief fenylglycidylzuurderivaat.

Country Status (9)

Country Link
EP (1) EP0860439B1 (ja)
JP (1) JPH10279572A (ja)
CN (1) CN1197070A (ja)
AT (1) ATE202094T1 (ja)
CA (1) CA2228196A1 (ja)
DE (1) DE69800900D1 (ja)
HU (1) HUP9800372A3 (ja)
IL (1) IL123391A0 (ja)
NL (1) NL1005338C2 (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1302261B1 (it) * 1998-09-24 2000-09-05 Zambon Spa Processo per la risoluzione cinetica enzimatica di 3-fenilglicidatiper transesterificazione con amminoalcoli
US7060471B2 (en) * 2003-03-12 2006-06-13 Council Of Scientific & Industrial Research Stereoselective chemoenzymatic process for the preparation of optically enriched phenylglycidates as precursors of taxol side chain

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0342904A2 (en) * 1988-05-18 1989-11-23 MARION LABORATORIES, INC. (a Delaware corporation) 2-Hydroxy-3-(4-methoxyphenyl)-3-(2-aminophenylthio)propionic acid, 8'-phenylmenthyl ester, especially for diltiazem

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0342904A2 (en) * 1988-05-18 1989-11-23 MARION LABORATORIES, INC. (a Delaware corporation) 2-Hydroxy-3-(4-methoxyphenyl)-3-(2-aminophenylthio)propionic acid, 8'-phenylmenthyl ester, especially for diltiazem

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
A. SCHWARTZ ET AL.: "Enantioselective synthesis of calcium channel blockers of the diltiazem group", JOURNAL OF ORGANIC CHEMISTRY, vol. 57, no. 3, 1992, WASHINGTON DC, US, pages 851 - 6, XP002042991 *

Also Published As

Publication number Publication date
IL123391A0 (en) 1998-09-24
EP0860439B1 (en) 2001-06-13
HUP9800372A3 (en) 2001-02-28
CA2228196A1 (en) 1998-08-21
HU9800372D0 (en) 1998-04-28
DE69800900D1 (de) 2001-07-19
CN1197070A (zh) 1998-10-28
ATE202094T1 (de) 2001-06-15
HUP9800372A2 (hu) 1999-09-28
EP0860439A1 (en) 1998-08-26
JPH10279572A (ja) 1998-10-20

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