MXPA03004136A - Derivados de pirimidina y su uso como ligandos del receptor de neuropeptido y (npy). - Google Patents
Derivados de pirimidina y su uso como ligandos del receptor de neuropeptido y (npy).Info
- Publication number
- MXPA03004136A MXPA03004136A MXPA03004136A MXPA03004136A MXPA03004136A MX PA03004136 A MXPA03004136 A MX PA03004136A MX PA03004136 A MXPA03004136 A MX PA03004136A MX PA03004136 A MXPA03004136 A MX PA03004136A MX PA03004136 A MXPA03004136 A MX PA03004136A
- Authority
- MX
- Mexico
- Prior art keywords
- neuropeptide
- receptor ligands
- pyrimidine derivatives
- pyrimidine
- derivatives
- Prior art date
Links
- 108050002826 Neuropeptide Y Receptor Proteins 0.000 title 1
- 102000012301 Neuropeptide Y receptor Human genes 0.000 title 1
- 239000003446 ligand Substances 0.000 title 1
- 229940083082 pyrimidine derivative acting on arteriolar smooth muscle Drugs 0.000 title 1
- 150000003230 pyrimidines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00124610 | 2000-11-10 | ||
| PCT/EP2001/012818 WO2002038551A1 (en) | 2000-11-10 | 2001-11-06 | Pyrimidine derivatives and their use as neuropeptide y receptor ligands |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MXPA03004136A true MXPA03004136A (es) | 2003-08-19 |
Family
ID=8170342
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MXPA03004136A MXPA03004136A (es) | 2000-11-10 | 2001-11-06 | Derivados de pirimidina y su uso como ligandos del receptor de neuropeptido y (npy). |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6657060B2 (es) |
| EP (1) | EP1335906B1 (es) |
| JP (1) | JP2004524279A (es) |
| KR (1) | KR100611853B1 (es) |
| CN (1) | CN1473156A (es) |
| AR (1) | AR034700A1 (es) |
| AT (1) | ATE340784T1 (es) |
| AU (2) | AU2790502A (es) |
| BR (1) | BR0115045A (es) |
| CA (1) | CA2427350A1 (es) |
| DE (1) | DE60123458T2 (es) |
| DK (1) | DK1335906T3 (es) |
| ES (1) | ES2271100T3 (es) |
| MX (1) | MXPA03004136A (es) |
| PA (1) | PA8531701A1 (es) |
| PE (1) | PE20020603A1 (es) |
| PT (1) | PT1335906E (es) |
| UY (1) | UY27018A1 (es) |
| WO (1) | WO2002038551A1 (es) |
| ZA (1) | ZA200302970B (es) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003214110A1 (en) * | 2002-03-15 | 2003-09-29 | Ciba Specialty Chemicals Holding Inc. | 4-aminopyrimidines and their use for the antimicrobial treatment of surfaces |
| GB0428328D0 (en) | 2004-12-24 | 2005-02-02 | Astrazeneca Uk Ltd | Chemical process |
| US7768604B2 (en) * | 2005-09-20 | 2010-08-03 | Au Optronics Corporation | Transflective liquid crystal display with partially shifted reflectivity curve |
| JP2009523161A (ja) * | 2006-01-11 | 2009-06-18 | アストラゼネカ アクチボラグ | モルホリノピリミジン誘導体と療法におけるその使用 |
| KR101435231B1 (ko) | 2006-08-24 | 2014-10-02 | 아스트라제네카 아베 | 증식성 질환의 치료에 유용한 모르폴리노 피리미딘 유도체 |
| EP2057129A1 (en) * | 2006-08-24 | 2009-05-13 | AstraZeneca AB | Morpholino pyrimidine derivatives useful in the treatment of proliferative disorders |
| EP2074118A2 (en) * | 2007-07-09 | 2009-07-01 | AstraZeneca AB | Trisubstituted pyrimidine derivatives for the treatment of proliferative diseases |
| CN101809002B (zh) | 2007-07-09 | 2013-03-27 | 阿斯利康(瑞典)有限公司 | 用于与mtor激酶和/或pi3k相关的疾病中的吗啉代嘧啶衍生物 |
| KR20100042643A (ko) * | 2007-07-09 | 2010-04-26 | 아스트라제네카 아베 | 증식성 질환을 치료하기 위한 삼중치환된 피리미딘 유도체 |
| EP2178866A2 (en) * | 2007-07-09 | 2010-04-28 | AstraZeneca AB | Trisubstituted pyrimidine derivatives for the treatment of proliferative diseases |
| US20110166135A1 (en) * | 2008-09-10 | 2011-07-07 | Hiroshi Morimoto | Aromatic nitrogen-containing 6-membered ring compounds and their use |
| UY32351A (es) * | 2008-12-22 | 2010-07-30 | Astrazeneca Ab | Compuestos de pirimidinil indol para uso como inhibidores de atr |
| JP2011201873A (ja) * | 2010-03-03 | 2011-10-13 | Mitsubishi Tanabe Pharma Corp | 三置換ピリミジン化合物及びそのｐｄｅ１０阻害薬としての使用 |
| CN102858342B (zh) * | 2010-03-11 | 2014-12-10 | 塔加西普特公司 | 用于便秘的芳基乙烯基氮杂环烷烃化合物 |
| SA111320519B1 (ar) | 2010-06-11 | 2014-07-02 | Astrazeneca Ab | مركبات بيريميدينيل للاستخدام كمثبطات atr |
| WO2015039292A1 (zh) * | 2013-09-18 | 2015-03-26 | 华安医学股份有限公司 | 一种活化ampk的化合物及其用途 |
| CN112375042A (zh) * | 2020-10-27 | 2021-02-19 | 安徽医科大学 | 三甲氧基苯乙烯基六元环类和吡唑并嘧啶类化合物、制剂及其制备与应用 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH024345A (ja) * | 1988-06-15 | 1990-01-09 | Matsushita Electric Ind Co Ltd | 超音波変換装置 |
| JPH0720467B2 (ja) * | 1988-06-15 | 1995-03-08 | 松下電器産業株式会社 | 超音波診断装置 |
| US5728704A (en) * | 1992-09-28 | 1998-03-17 | Pfizer Inc. | Substituted pyridmidines for control of diabetic complications |
| DE69724941T2 (de) | 1996-03-21 | 2004-07-15 | Banyu Pharmaceutical Co., Ltd. | Aminopyridin-derivate |
| WO1998040356A1 (fr) * | 1997-03-12 | 1998-09-17 | Banyu Pharmaceutical Co., Ltd. | Medicaments contenant des derives d'aminopyridine comme ingredient actif |
-
2001
- 2001-11-06 AT AT01989438T patent/ATE340784T1/de not_active IP Right Cessation
- 2001-11-06 DE DE60123458T patent/DE60123458T2/de not_active Expired - Fee Related
- 2001-11-06 AU AU2790502A patent/AU2790502A/xx active Pending
- 2001-11-06 PT PT01989438T patent/PT1335906E/pt unknown
- 2001-11-06 CN CNA018186343A patent/CN1473156A/zh active Pending
- 2001-11-06 ES ES01989438T patent/ES2271100T3/es not_active Expired - Lifetime
- 2001-11-06 WO PCT/EP2001/012818 patent/WO2002038551A1/en active IP Right Grant
- 2001-11-06 BR BR0115045-6A patent/BR0115045A/pt not_active IP Right Cessation
- 2001-11-06 JP JP2002541086A patent/JP2004524279A/ja active Pending
- 2001-11-06 DK DK01989438T patent/DK1335906T3/da active
- 2001-11-06 CA CA002427350A patent/CA2427350A1/en not_active Abandoned
- 2001-11-06 EP EP01989438A patent/EP1335906B1/en not_active Expired - Lifetime
- 2001-11-06 KR KR1020037006306A patent/KR100611853B1/ko not_active IP Right Cessation
- 2001-11-06 AU AU2002227905A patent/AU2002227905B2/en not_active Ceased
- 2001-11-06 MX MXPA03004136A patent/MXPA03004136A/es active IP Right Grant
- 2001-11-07 PA PA20018531701A patent/PA8531701A1/es unknown
- 2001-11-08 PE PE2001001110A patent/PE20020603A1/es not_active Application Discontinuation
- 2001-11-08 US US10/008,166 patent/US6657060B2/en not_active Expired - Fee Related
- 2001-11-08 AR ARP010105229A patent/AR034700A1/es unknown
- 2001-11-09 UY UY27018A patent/UY27018A1/es not_active Application Discontinuation
-
2003
- 2003-04-15 ZA ZA200302970A patent/ZA200302970B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002038551A1 (en) | 2002-05-16 |
| US20020086858A1 (en) | 2002-07-04 |
| AU2790502A (en) | 2002-05-21 |
| DE60123458D1 (de) | 2006-11-09 |
| AR034700A1 (es) | 2004-03-17 |
| ZA200302970B (en) | 2004-07-15 |
| DK1335906T3 (da) | 2007-02-05 |
| DE60123458T2 (de) | 2007-08-02 |
| PA8531701A1 (es) | 2003-06-30 |
| EP1335906B1 (en) | 2006-09-27 |
| PT1335906E (pt) | 2007-01-31 |
| PE20020603A1 (es) | 2002-07-20 |
| BR0115045A (pt) | 2004-02-03 |
| ATE340784T1 (de) | 2006-10-15 |
| ES2271100T3 (es) | 2007-04-16 |
| AU2002227905B2 (en) | 2006-10-05 |
| CA2427350A1 (en) | 2002-05-16 |
| CN1473156A (zh) | 2004-02-04 |
| JP2004524279A (ja) | 2004-08-12 |
| KR100611853B1 (ko) | 2006-08-11 |
| EP1335906A1 (en) | 2003-08-20 |
| KR20040004432A (ko) | 2004-01-13 |
| US6657060B2 (en) | 2003-12-02 |
| UY27018A1 (es) | 2002-06-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant or registration |