MX9704824A - Adyuvantes para vacunas. - Google Patents

Adyuvantes para vacunas.

Info

Publication number
MX9704824A
MX9704824A MX9704824A MX9704824A MX9704824A MX 9704824 A MX9704824 A MX 9704824A MX 9704824 A MX9704824 A MX 9704824A MX 9704824 A MX9704824 A MX 9704824A MX 9704824 A MX9704824 A MX 9704824A
Authority
MX
Mexico
Prior art keywords
adjuvants
vaccine
vaccine adjuvants
sulpholipid
polysaccharide
Prior art date
Application number
MX9704824A
Other languages
English (en)
Other versions
MXPA97004824A (es
Inventor
Luuk Hilgers
Original Assignee
Dimminaco Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=3888560&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX9704824(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Dimminaco Ag filed Critical Dimminaco Ag
Publication of MX9704824A publication Critical patent/MX9704824A/es
Publication of MXPA97004824A publication Critical patent/MXPA97004824A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
    • C08B37/0012—Cyclodextrin [CD], e.g. cycle with 6 units (alpha), with 7 units (beta) and with 8 units (gamma), large-ring cyclodextrin or cycloamylose with 9 units or more; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55583—Polysaccharides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Mycology (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Los adyuvantes para vacunas comprenden un polisacárido sulfolipídico en combinacion con un constituyente que forma una interfase. La invencion también proporciona un método para preparar una vacuna emulsificando una solucion acuosa de un antígeno y un polisacárido sulfolipídico. Los adyuvantes son estables a altas temperaturas y son al menos tan efectivos como los adyuvantes convencionales. su toxicidad local, es decir su reactogenicidad es generalmente más baja que la de los adyuvantes convencionales.
MXPA/A/1997/004824A 1994-12-27 1997-06-26 Adyuvantes para vacunas MXPA97004824A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BE9401174A BE1008978A5 (fr) 1994-12-27 1994-12-27 Adjuvants pour vaccins.
BE9401174 1994-12-27

Publications (2)

Publication Number Publication Date
MX9704824A true MX9704824A (es) 1998-06-30
MXPA97004824A MXPA97004824A (es) 1998-10-30

Family

ID=

Also Published As

Publication number Publication date
WO1996020008A1 (fr) 1996-07-04
BR9510263A (pt) 1997-11-04
DK0814836T3 (da) 2001-04-17
JPH10511997A (ja) 1998-11-17
CA2208790A1 (en) 1996-07-04
EP0800539A1 (en) 1997-10-15
PT814836E (pt) 2001-07-31
ATE248863T1 (de) 2003-09-15
MX9704822A (es) 1998-05-31
EP0814836A1 (fr) 1998-01-07
CA2208849C (en) 2006-10-10
EP0800539B1 (en) 2003-09-03
BE1008978A5 (fr) 1996-10-01
JPH11502192A (ja) 1999-02-23
AU4324896A (en) 1996-07-19
JP4087900B2 (ja) 2008-05-21
DE69531699T2 (de) 2004-07-08
AU709104B2 (en) 1999-08-19
GR3035941T3 (en) 2001-08-31
EP0814836B1 (fr) 2001-03-14
BR9510223A (pt) 1997-12-30
CN1175264A (zh) 1998-03-04
CN1132630C (zh) 2003-12-31
DK0800539T3 (da) 2003-12-08
CA2208849A1 (en) 1996-07-04
WO1996020222A1 (en) 1996-07-04
CN1171052A (zh) 1998-01-21
ES2204969T3 (es) 2004-05-01
JP3927235B2 (ja) 2007-06-06
DE69520376T2 (de) 2001-08-09
AU4324996A (en) 1996-07-19
PT800539E (pt) 2004-01-30
SI0800539T1 (en) 2003-12-31
ES2155540T3 (es) 2001-05-16
CA2208790C (en) 2012-01-31
DE69520376D1 (de) 2001-04-19
ATE199644T1 (de) 2001-03-15
US6165995A (en) 2000-12-26
DE69531699D1 (de) 2003-10-09
US6328965B1 (en) 2001-12-11
AU713997B2 (en) 1999-12-16
CN1109049C (zh) 2003-05-21

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Legal Events

Date Code Title Description
FG Grant or registration
GB Transfer or rights
GB Transfer or rights
HC Change of company name or juridical status