MX370253B - Composiciones de compuestos de jasmonato y métodos de uso de las mismas. - Google Patents

Composiciones de compuestos de jasmonato y métodos de uso de las mismas.

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Publication number
MX370253B
MX370253B MX2014003301A MX2014003301A MX370253B MX 370253 B MX370253 B MX 370253B MX 2014003301 A MX2014003301 A MX 2014003301A MX 2014003301 A MX2014003301 A MX 2014003301A MX 370253 B MX370253 B MX 370253B
Authority
MX
Mexico
Prior art keywords
compositions
methods
compounds
jasmonate compounds
nanocarried
Prior art date
Application number
MX2014003301A
Other languages
English (en)
Other versions
MX2014003301A (es
Inventor
Pereira Lopes Jose E Fehr
Original Assignee
Nanocare Tech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/IB2012/000364 external-priority patent/WO2012114196A1/pt
Application filed by Nanocare Tech Inc filed Critical Nanocare Tech Inc
Publication of MX2014003301A publication Critical patent/MX2014003301A/es
Publication of MX370253B publication Critical patent/MX370253B/es

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    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L101/00—Compositions of unspecified macromolecular compounds
    • C08L101/005—Dendritic macromolecules
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2205/00—Polymer mixtures characterised by other features
    • C08L2205/14—Polymer mixtures characterised by other features containing polymeric additives characterised by shape
    • C08L2205/18—Spheres

Abstract

La invención describe compuestos de jasmonato nanotransportados y/o microtransportados y sus composiciones farmacéuticas, así como el uso de los mismos, para tratar o prevenir trastornos relacionados con la angiogénesis o trastornos relacionados con NF-?B; se describen también métodos para elaborar los compuestos nanoportados y/o microportados y sus composiciones.
MX2014003301A 2011-09-16 2012-09-17 Composiciones de compuestos de jasmonato y métodos de uso de las mismas. MX370253B (es)

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US201161535836P 2011-09-16 2011-09-16
US201161555690P 2011-11-04 2011-11-04
US201261603042P 2012-02-24 2012-02-24
PCT/IB2012/000364 WO2012114196A1 (pt) 2011-02-25 2012-02-27 Formulação farmacêutica compreendendo compostos da família dos jasmonatos
US201261607318P 2012-03-06 2012-03-06
US201261612774P 2012-03-19 2012-03-19
PCT/US2012/055757 WO2013040556A1 (en) 2011-09-16 2012-09-17 Compositions of jasmonate compounds and methods of use

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Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2012221877A1 (en) * 2011-02-25 2013-09-19 Nanocare Technologies, Inc. Pharmaceutical formulation comprising compounds of the jasmonate family
JP2014526519A (ja) 2011-09-16 2014-10-06 ナノケア テクノロジーズ，インコーポレイティド ジャスモネート化合物の組成物および使用方法
JP2014122191A (ja) * 2012-12-21 2014-07-03 L'oreal Sa 油、非イオン界面活性剤及びジャスモン酸誘導体を含む化粧品組成物
CN104902864B (zh) 2012-12-21 2020-09-01 莱雅公司 化妆品组合物
US20150230462A1 (en) * 2014-01-15 2015-08-20 New Biology, Inc. Methods for improving germination and stress tolerance characteristics with jasmonates
MX2017008655A (es) * 2014-12-31 2018-04-10 Nanocare Tech Inc Derivados de jasmonato y composiciones de los mismos.
CN108778263A (zh) * 2016-03-28 2018-11-09 维达克制药有限公司 用于局部用药的稳定药物组合物及其用途
US10410943B2 (en) 2016-10-13 2019-09-10 Asm Ip Holding B.V. Method for passivating a surface of a semiconductor and related systems
WO2018083705A1 (en) * 2016-11-07 2018-05-11 Vidac Pharma Ltd. Use of hexokinase 2/mitochondria-detaching compounds for treating hexokinase-2 (hk2)-expressing cancers
US10682346B2 (en) 2016-11-07 2020-06-16 Vidac Pharma Ltd. Use of hexokinase 2/mitochondria-detaching compounds for activating immune responses
KR102275801B1 (ko) * 2019-12-24 2021-07-09 경희대학교 산학협력단 시스-자스몬을 포함하는 바이오필름 형성 억제용 조성물

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2073507T3 (es) 1989-04-12 1995-08-16 Procter & Gamble Composiciones de productos solidos de consumo que contienen complejos con ciclodextrina en forma de pequeñas particulas.
CA2013485C (en) 1990-03-06 1997-04-22 John Michael Gardlik Solid consumer product compositions containing small particle cyclodextrin complexes
US5576016A (en) * 1993-05-18 1996-11-19 Pharmos Corporation Solid fat nanoemulsions as drug delivery vehicles
JP3568325B2 (ja) * 1996-07-12 2004-09-22 株式会社ノエビア 抗アンドロゲン剤及び養毛剤並びに毛髪用化粧料
JP3596835B2 (ja) 1996-08-13 2004-12-02 株式会社ノエビア 養毛剤
BR9810429A (pt) 1997-06-09 2000-09-19 Procter & Gamble Composições perfumadas e métodos para reprodução de odores do corpo e excesso de umidade
US6790815B1 (en) 1998-07-10 2004-09-14 Procter & Gamble Company Amine reaction compounds comprising one or more active ingredient
CA2274873A1 (en) 1999-07-06 2001-01-06 Satinder Gidda Methods and compositions for modulating flowering
AU2002245629A1 (en) 2001-03-08 2002-09-24 Targesome, Inc. Stabilized therapeutic and imaging agents
US6469061B1 (en) 2001-04-04 2002-10-22 Ramot University Authority For Applied Research And Industrial Development Limited Jasmonate pharmaceutical composition for treatment of cancer
US20030224024A1 (en) 2002-02-04 2003-12-04 Jean-Luc Leveque Compositions comprising cyclopentane derivatives and their use
US20040209795A1 (en) * 2003-04-21 2004-10-21 Vlad Florin Joseph VOC-free microemulsions
US7425651B2 (en) 2003-12-02 2008-09-16 Ramot At Tel-Aviv University Ltd. Jasmonate derivative compounds, pharmaceuticals compounds and methods of use thereof
KR100789343B1 (ko) 2004-09-07 2007-12-28 주식회사 엘지생활건강 화장용 분체, 그의 제조방법 및 이를 함유하는 메이컵화장품 조성물
US20080044364A1 (en) 2004-11-25 2008-02-21 Christophe Carola Flavonoid Complexes
US7258878B2 (en) 2004-12-20 2007-08-21 Kimberly-Clark Worldwide, Inc. Anti-microbial composition and methods of use thereof
ES2265291B1 (es) 2005-07-22 2008-03-01 Universidad De Alcala Nuevos dendrimeros carbosilanos, su preparacion y sus usos.
AU2006322845A1 (en) 2005-12-07 2007-06-14 Sepal Pharma Ltd. Jasmonate derivatives, pharmaceutical compositions and methods of use thereof
US20090291904A1 (en) 2005-12-07 2009-11-26 Yoel Kashman Chemical derivatives of jasmonate, pharmaceutical compositions and methods of use thereof
WO2007103336A2 (en) 2006-03-06 2007-09-13 The Board Of Trustees Operating Micro-encapsulation of volatile compounds into cyclodextrins
AU2006344479A1 (en) 2006-06-13 2007-12-21 Cargill, Incorporated Large-particle cyclodextrin inclusion complexes and methods of preparing same
BRPI0714046A2 (pt) 2006-07-10 2013-04-24 Univ Ramot mÉtodos de combinaÇço para tratar cÂncer
BRPI0604024A (pt) 2006-09-01 2008-04-22 Beyond Lifescience Pesquisa De alimentos para a prevenção do cáncer e composições farmacêuticas à base do jasmonato
US20100160623A1 (en) 2006-12-27 2010-06-24 Cargill, Incorporated Cyclodextrin inclusion complexes and methods of preparing same
WO2009019693A2 (en) * 2007-08-07 2009-02-12 Sepal Pharma Sa Analgesic effect of jasmonate derivatives
AU2008303129B2 (en) 2007-09-25 2013-08-01 Formulex Pharma Innovations Ltd. Compositions comprising lipophilic active compounds and method for their preparation
GB0721761D0 (en) 2007-11-06 2007-12-19 Plant Bioscience Ltd Compositions and methods for synergistic manipulation of plant and insect defences
WO2009067404A2 (en) * 2007-11-19 2009-05-28 New Biology, Inc. Methods for improving flowering characteristics using methyl dihydrojasmonate
US20090197939A1 (en) * 2008-02-01 2009-08-06 Mary Kay Inc. Methods of treating skin with aromatic skin-active ingredients
ES2328002B2 (es) 2008-02-29 2010-03-29 Universidad De Alicante Uso combinado de metil-jasmonato y ciclodextrinas para la produccion de resveratrol.
BRPI0804172A2 (pt) * 2008-07-15 2010-07-06 Pereira Lopes Jose Emilio Fehr compostos quìmicos formados a partir de nanoencapsulamentos e complexação de elementos
WO2010143180A1 (en) * 2009-06-09 2010-12-16 Sepal Pharma Ltd. Use of jasmonate ester derivatives for treating benign hyperproliferative skin disorders
CN101818100B (zh) * 2010-04-15 2012-06-06 上海应用技术学院 聚氰基丙烯酸丁酯包覆大花茉莉香精胶囊的制备方法
CN103168018B (zh) 2010-08-27 2015-10-21 尼昂克技术公司 包含poh衍生物的药物组合物
AU2012221877A1 (en) 2011-02-25 2013-09-19 Nanocare Technologies, Inc. Pharmaceutical formulation comprising compounds of the jasmonate family
JP2014526519A (ja) 2011-09-16 2014-10-06 ナノケア テクノロジーズ，インコーポレイティド ジャスモネート化合物の組成物および使用方法
EP2583998B1 (en) 2011-10-21 2018-02-28 Borealis AG Polyethylene composition with high rapid crack propagation resistance and pressure resistance
US9187402B2 (en) 2012-06-14 2015-11-17 North Carolina Agricultural And Technical State University Aspirin derivatives and uses thereof
CN104540525A (zh) 2012-07-10 2015-04-22 贝瑟克里科有限公司 ***素修饰的核酸分子
MX2017008655A (es) 2014-12-31 2018-04-10 Nanocare Tech Inc Derivados de jasmonato y composiciones de los mismos.

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RU2014114931A (ru) 2015-10-27
CN107970213A (zh) 2018-05-01
WO2013040556A1 (en) 2013-03-21
BR112014006153A2 (pt) 2020-12-01
KR20190108189A (ko) 2019-09-23
US10328155B2 (en) 2019-06-25
HK1254825A1 (zh) 2019-07-26
CN104203222A (zh) 2014-12-10
KR102023132B1 (ko) 2019-09-19
US20180000958A1 (en) 2018-01-04
JP2014526519A (ja) 2014-10-06
US9592305B2 (en) 2017-03-14
EP2755643B1 (en) 2019-05-08
EP2755643A4 (en) 2015-09-23
CA2848219A1 (en) 2013-03-21
US8883220B2 (en) 2014-11-11
JP2017222659A (ja) 2017-12-21
US20130089615A1 (en) 2013-04-11
KR20140090602A (ko) 2014-07-17
MX2014003301A (es) 2014-10-14
US20150140110A1 (en) 2015-05-21
JP2019077702A (ja) 2019-05-23

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